A multistep process gave rise to RNA polymerase IV of land plants.

Abstract:

:Since their discovery in Metazoa, the three nuclear RNA polymerases (RNAPs) have been found in fungi, plants, and diverse protists. In all eukaryotes studied to date, RNAPs I, II, and III collectively transcribe all major RNAs made in the nucleus. We have found genes for the largest subunit (RPD1/RPE1) of a new DNA-dependent RNAP, RNAP IV, in all major land plant taxa and in closely related green algae. Genes for the second-largest subunit (RPD2) of this enzyme were found in all land plants. Phylogenetic study indicates that RNAP IV genes are sister to the corresponding RNAP II genes. Our results show the genesis of RNAP IV to be a multistep process in which the largest and second-largest subunit genes evolved by independent duplication events in the ancestors of Charales and land plants. These findings provide insights into evolutionary mechanisms that can explain the origin of multiple RNAPs in the eukaryotic nucleus.

journal_name

J Mol Evol

authors

Luo J,Hall BD

doi

10.1007/s00239-006-0093-z

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

101-12

issue

1

eissn

0022-2844

issn

1432-1432

journal_volume

64

pub_type

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