Multiple forms of male-specific simple repetitive sequences in the genus Mus.

Abstract:

:Previous reports indicate that in laboratory strains of mice, males are distinct from females in possession of repetitive DNA, notably devoid of Eco RI and Hae III sites and rich in the simple tetranucleotides GATA/GACA. We report here that such sequences originated in an ancestor common to laboratory mice, Mus hortulanus, M. spretus, and possibly also M. cookii. Interestingly, other male-specific satellite sequences were detected in M. caroli, M. cookii, M. saxicola, and M. minutoides. This novel satellite is also likely to be composed of simple repetitious sequences, but does not contain GATA and GACA. Thus, the Y chromosome appears to contain a disproportionately large amount of simple repetitious DNA. An attractive explanation for these results is that long tandem arrays of simple repeated sequences are generated at high frequency throughout the genome and that they are retained for a longer time on the Y chromosome due to the absence of homologous pairing at meiosis.

journal_name

J Mol Evol

authors

Platt TH,Dewey MJ

doi

10.1007/BF02100013

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

201-6

issue

3

eissn

0022-2844

issn

1432-1432

journal_volume

25

pub_type

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