Abstract：
:Short interspersed DNA elements (SINEs) amplify by retroposition either by (i) successive waves of amplification from one or a few evolving master genes or by (ii) the generation of new master genes that coexist with their progenitors. Individual, highly conserved, elements of the B1 SINE family were identified from the GenBank nucleotide database using various B1 subfamily consensus query sequences to determine their integration times into the mouse genome. A comparison of orthologous loci in various species of the genus Mus demonstrated that four subfamilies of B1 elements have been amplifying within the last 1-3 million years. Therefore, B1 sequences are generated by coexisting source genes. Additionally, three B1 subfamilies have been concurrently propagated during subspecies divergence and strain formation in Mus, indicating very recent activity of this retroposon family. The patterns of intra- and interspecies variations of orthologous loci demonstrate the usefulness of B1 integrations as a phylogenetic tool. A single inconsistency in the phylogenetic trends was depicted by the presence of a B1 insert in an orthologous locus exclusively in M. musculus and M. pahari. However, DNA sequence analysis revealed that these were independent integrations at the same genomic site. One highly conserved B1 element that integrated at least 4-6 million years ago suggests the possibility of occasional function for B1 integrations.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Kass DH,Raynor ME,Williams TMdoi
10.1007/s002390010087keywords:
subject
Has Abstractpub_date
2000-09-01 00:00:00pages
256-64issue
3eissn
0022-2844issn
1432-1432pii
10.1007/s002390010087journal_volume
51pub_type
杂志文章abstract：:We have identified and completely sequenced a novel plasmid isolated from the aphid Rhopalosiphum padi. Evidence which suggests that the plasmid occurs localized within the bacterial endosymbionts is presented. The plasmid contains the four genes that constitute the entire leucine operon. This fact makes it really uni...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
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journal_title：Journal of molecular evolution
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006474
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pub_type： 杂志文章
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journal_title：Journal of molecular evolution
pub_type： 评论,杂志文章
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journal_title：Journal of molecular evolution
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journal_title：Journal of molecular evolution
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
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更新日期：1996-06-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00182743
更新日期：1993-12-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-004-2640-9
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pub_type： 杂志文章
doi：10.1007/s00239-012-9504-5
更新日期：2012-06-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-005-0196-y
更新日期：2006-08-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-004-0240-3
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