ApA dinucleotide periodicity in prokaryote, eukaryote, and organelle genomes.

abstract：:Evaporation of a solution of thymidine plus either the exo or the endo diastereomer of uridine cyclic 2',3'-O, O-phosphorothioate (U greater than p(S) in 1,2-diaminoethane hydrochloride buffer gave the 2',5' and 3',5' isomers of (P-thio) uridylylthymidine (Up(S)dT) in a ratio of 1:2 with a combined yield of about 20%....

journal_title：Journal of molecular evolution

authors： Usher DA,Yee D

更新日期：1979-11-01 00:00:00

abstract：:Cyclooxygenase (COX) enzymatically converts arachidonic acid into prostaglandin G/H in animals and has importance during pregnancy, digestion, and other physiological functions in mammals. COX genes have mainly been described from vertebrates, where gene duplications are common, but few studies have examined COX in in...

journal_title：Journal of molecular evolution

authors： Havird JC,Kocot KM,Brannock PM,Cannon JT,Waits DS,Weese DA,Santos SR,Halanych KM

更新日期：2015-04-01 00:00:00

abstract：:A systematic way of inferring evolutionary relatedness of microbial organisms from the oligopeptide content, i.e., frequency of amino acid K-strings in their complete proteomes, is proposed. The new method circumvents the ambiguity of choosing the genes for phylogenetic reconstruction and avoids the necessity of align...

journal_title：Journal of molecular evolution

authors： Qi J,Wang B,Hao BI

更新日期：2004-01-01 00:00:00

abstract：:This report describes the distribution of P-element sequences among members of the closely related willistoni and saltans species groups of the subgenus Sophophora. Gel-blotting analyses showed that many, but not all, species from each of these groups possess sequences with homology to the P transposable element of Dr...

journal_title：Journal of molecular evolution

authors： Daniels SB,Strausbaugh LD

更新日期：1986-01-01 00:00:00

abstract：:Nuclear DNA contents were estimated by microdensitometry in five species of Akodon rodents: Arodon molinae, A. dolores, A. mollis, A. azarae, Bolomys obscurus) and in three chromosomal varieties of A. molinae (2n = 42; 2n = 43, 2n = 22). The data obtained showed that the species with the highest DNA content was B. obs...

journal_title：Journal of molecular evolution

authors： Bianchi NO,Redi C,Garagna C,Capanna E,Manfredi-Romanini MG

更新日期：1983-01-01 00:00:00

abstract：:In Trypanoplasma borelli, a representative of the Bodonina within the Kinetoplastida, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity was detected in both the cytosol and glycosomes. This situation is similar to that previously found in Trypanosomatidae, belonging to a different Kinetoplastida suborder. In T...

journal_title：Journal of molecular evolution

authors： Wiemer EA,Hannaert V,van den IJssel PR,Van Roy J,Opperdoes FR,Michels PA

更新日期：1995-04-01 00:00:00

abstract：:From the cloned mitochondrial DNAs (mtDNAs) isolated from two bisexual species, one Mediterranean, Artemia salina, and one American, Artemia franciscana, and two parthenogenetic (diploid and tetraploid) strains of Artemia parthenogenetica collected in Spain, physical maps have been constructed and compared. They are e...

journal_title：Journal of molecular evolution

authors： Perez ML,Valverde JR,Batuecas B,Amat F,Marco R,Garesse R

更新日期：1994-02-01 00:00:00

abstract：:We have implemented a routine procedure for screening protein sequences for evidence of intragenic duplications. We tested 163 protein sequences representing 116 superfamilies of unrelated proteins. Twenty superfamilies contain proteins with internal gene duplications. The intragenic duplications detected can be divid...

journal_title：Journal of molecular evolution

authors： Barker WC,Ketcham LK,Dayhoff MO

更新日期：1978-02-21 00:00:00

abstract：:We have performed DNA-DNA hybridization experiments among several species of Drosophila using the evolutionarily conserved portion of the genome representing sequences coding for amino acids of proteins. This was done by using as tracer, radioactively labeled complementary DNA that was reverse transcribed from adult m...

journal_title：Journal of molecular evolution

authors： Caccone A,Gleason JM,Powell JR

更新日期：1992-02-01 00:00:00

abstract：:We have studied the metal-ion catalysis of a number of reactions of the isomers of ImpGpG on a poly(C) template. In the absence of a catalytic metal ion, oligomers at least up to (pG)20 are obtained from the ImpGpG isomers in a 1-methylimidazole buffer. The Pb2+ ion improves the yield of longer oligomers and changes s...

journal_title：Journal of molecular evolution

authors： Lohrmann R,Bridson PK,Orgel LE

更新日期：1981-01-01 00:00:00

abstract：:The helix-turn-helix domain-containing family of transcriptional regulators is of ancient origin and has been incorporated into numerous disparate biological processes. As a consequence, the forces shaping its early evolution have been difficult to reconstruct. Herein, we analyze this large and diverse family with a c...

journal_title：Journal of molecular evolution

authors： Rosinski JA,Atchley WR

更新日期：1999-09-01 00:00:00

abstract：:Many proteins exhibit sequence periodicity, often correlated with a visible structural periodicity. The statistical significance of such periodicity can be assessed by means of a chi-squared-based test, with significance thresholds being calculated from shuffled sequences. Comparison of the complete proteomes of 45 sp...

journal_title：Journal of molecular evolution

authors： Gatherer D,McEwan NR

更新日期：2005-04-01 00:00:00

abstract：:A reaction which oligomerizes nucleotides under possible prebiotic conditions has been characterized. Nucleoside monophosphate in the presence of cyanamide at acid pH condenses to form dithymideine pyrophosphate and phosphodiester bonded compounds. Imidazole compounds and activated precursors such as nucleoside tripho...

journal_title：Journal of molecular evolution

authors： Odom DG,Brady JT

更新日期：1975-11-04 00:00:00

abstract：:One of the pupal cuticle protein (PCP) genes has been found within an intron of a Drosophila housekeeping gene (the Gart locus) that encodes three enzymes involved in the purine pathway. This intronic gene has been described as a gene within a gene, and the gene is now called a "nested" gene. Because the intronic PCP ...

journal_title：Journal of molecular evolution

authors： Moriyama EN,Gojobori T

更新日期：1989-05-01 00:00:00

abstract：:Single-fly polymerase chain reaction amplification and direct DNA sequencing revealed high levels of length polymorphism in the threonine-glycine encoding repeat region of the period (per) gene in natural populations of Drosophila melanogaster. DNA comparison of two alleles of identical lengths gave a high number of s...

journal_title：Journal of molecular evolution

authors： Costa R,Peixoto AA,Thackeray JR,Dalgleish R,Kyriacou CP

更新日期：1991-03-01 00:00:00

abstract：:We characterized the organization of mitochondrial genes from a diverse range of hymenopterans. Of the 21 taxa characterized, 12 had distinct, derived organizations. Some rearrangements were consistent with the duplication-random loss mechanism, while others were not. Local inversions were relatively common, i.e., rea...

journal_title：Journal of molecular evolution

authors： Dowton M,Castro LR,Campbell SL,Bargon SD,Austin AD

更新日期：2003-05-01 00:00:00

abstract：:The sequence of the mitochondrial DNA (mtDNA) molecule of the European hedgehog (Erinaceus europaeus) was determined. The length of the sequence presented is 17,442 nucleotides (nt). The molecule is thus the largest eutherian mtDNA molecule so far reported. The organization of the molecule conforms with that of other ...

journal_title：Journal of molecular evolution

authors： Krettek A,Gullberg A,Arnason U

更新日期：1995-12-01 00:00:00

abstract：:Since their discovery in Metazoa, the three nuclear RNA polymerases (RNAPs) have been found in fungi, plants, and diverse protists. In all eukaryotes studied to date, RNAPs I, II, and III collectively transcribe all major RNAs made in the nucleus. We have found genes for the largest subunit (RPD1/RPE1) of a new DNA-de...

journal_title：Journal of molecular evolution

authors： Luo J,Hall BD

更新日期：2007-01-01 00:00:00

abstract：:An exhaustive computer-assisted analysis of the Moloney murine leukemia virus nucleotide sequence shows numerous deviations in the oligomeric distribution, suggesting three overlapping levels of a stepwise duplicative evolution. (1) The sequence fits the universal rule of TG/CT excess which has been proposed as the co...

journal_title：Journal of molecular evolution

authors： Laprevotte I

更新日期：1992-11-01 00:00:00

abstract：:The 70-kDa heat-shock protein (HSP70) constitutes the most conserved protein present in all organisms that is known to date. Based on global alignment of HSP70 sequences from organisms representing all three domains, numerous sequence signatures that are specific for prokaryotic and eukaryotic homologs have been ident...

journal_title：Journal of molecular evolution

authors： Gupta RS,Golding GB

更新日期：1993-12-01 00:00:00

abstract：:Short interspersed DNA elements (SINEs) amplify by retroposition either by (i) successive waves of amplification from one or a few evolving master genes or by (ii) the generation of new master genes that coexist with their progenitors. Individual, highly conserved, elements of the B1 SINE family were identified from t...

journal_title：Journal of molecular evolution

authors： Kass DH,Raynor ME,Williams TM

更新日期：2000-09-01 00:00:00

abstract：:We have investigated the evolvability of an insoluble random polypeptide, RP3-34, to a soluble form through iterative mutation and selection with the aid of the green fluorescent protein (GFP) folding reporter. To assess the solubility of the polypeptides in the selected clones of each generation, the polypeptide gene...

journal_title：Journal of molecular evolution

authors： Ito Y,Kawama T,Urabe I,Yomo T

更新日期：2004-02-01 00:00:00

abstract：:The evolution of ligand specificity underlies many important problems in biology, from the appearance of drug resistant pathogens to the re-engineering of substrate specificity in enzymes. In studying biomolecules, however, the contributions of macromolecular sequence to binding specificity can be obscured by other se...

journal_title：Journal of molecular evolution

authors： Held DM,Greathouse ST,Agrawal A,Burke DH

更新日期：2003-09-01 00:00:00

abstract：:This paper presents an essentially new method used to construct phylogenetic trees from related amino acid sequences. The method is based on a new distance measure which describes sequence relationships by means of typical steric and physicochemical properties of the amino acids and is advantageous in some essential p...

journal_title：Journal of molecular evolution

authors： Schmidt W

更新日期：1995-10-01 00:00:00

abstract：:The accuracies and efficiencies of three different methods of making phylogenetic trees from gene frequency data were examined by using computer simulation. The methods examined are UPGMA, Farris' (1972) method, and Tateno et al.'s (1982) modified Farris method. In the computer simulation eight species (or populations...

journal_title：Journal of molecular evolution

authors： Nei M,Tajima F,Tateno Y

更新日期：1983-01-01 00:00:00

abstract：:Restriction modification (RM) systems serve to protect bacteria against bacteriophages. They comprise a restriction endonuclease activity that specifically cleaves DNA and a corresponding methyltransferase activity that specifically methylates the DNA, thereby protecting it from cleavage. Such systems are very common ...

journal_title：Journal of molecular evolution

authors： Jeltsch A,Pingoud A

更新日期：1996-02-01 00:00:00

abstract：:Sequence divergence among orthologous proteins was characterized with 34 amino acid replacement matrices, sequence context analysis, and a phylogenetic tree. The model was trained on very large datasets of aligned protein sequences drawn from 15 organisms including protists, plants, Dictyostelium, fungi, and animals. ...

journal_title：Journal of molecular evolution

authors： Olsen R,Loomis WF

更新日期：2005-11-01 00:00:00

abstract：:Available molecular and biochemical data offer conflicting evidence for the origin of the cyanelle of Cyanophora paradoxa. We show that the similarity of cyanelle and green chloroplast sequences is probably a result of these two lineages independently developing the same pattern of directional nucleotide change (subst...

journal_title：Journal of molecular evolution

authors： Lockhart PJ,Howe CJ,Bryant DA,Beanland TJ,Larkum AW

更新日期：1992-02-01 00:00:00

abstract：:In the present study we focus on the nucleotide and the inferred amino acid variation occurring in humans and other primate species for mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase, a gene recently supposed to contribute to cognitive performance in humans. We determined 2527 bp of coding, introni...

journal_title：Journal of molecular evolution

authors： Blasi P,Palmerio F,Aiello A,Rocchi M,Malaspina P,Novelletto A

更新日期：2006-07-01 00:00:00

abstract：:The relationships of genome organization among elongated (rod-shaped and filamentous) plant viruses have been analyzed. Sequences in coding and noncoding regions of barley stripe mosaic virus (BSMV) RNAs 1, 2, and 3 were compared with those of the monopartite RNA genomes of potato virus X (PVX), white clover mosaic vi...

journal_title：Journal of molecular evolution

authors： Morozov SYu,Dolja VV,Atabekov JG

更新日期：1989-07-01 00:00:00