Evolution of microsatellites in the yeast Saccharomyces cerevisiae: role of length and number of repeated units.

abstract：:Analysis of mitochondrial DNAs (mtDNAs) from parthenogenetic lizards of the Heteronotia binoei complex with restriction enzymes revealed an approximately 5-kb addition present in all 77 individuals. Cleavage site mapping suggested the presence of a direct tandem duplication spanning the 16S and 12S rRNA genes, the con...

journal_title：Journal of molecular evolution

authors： Zevering CE,Moritz C,Heideman A,Sturm RA

更新日期：1991-11-01 00:00:00

abstract：:The evolution of ligand specificity underlies many important problems in biology, from the appearance of drug resistant pathogens to the re-engineering of substrate specificity in enzymes. In studying biomolecules, however, the contributions of macromolecular sequence to binding specificity can be obscured by other se...

journal_title：Journal of molecular evolution

authors： Held DM,Greathouse ST,Agrawal A,Burke DH

更新日期：2003-09-01 00:00:00

abstract：:Low oxygen and fluctuant ambient temperature pose serious challenges to mammalian survival. Physiological adaptations in mammals to hypoxia and low temperatures have been intensively investigated, yet their underlying molecular mechanisms need further exploration. Independent invasions of high-altitude plateaus, subte...

journal_title：Journal of molecular evolution

authors： Zhu K,Ge D,Wen Z,Xia L,Yang Q

更新日期：2018-12-01 00:00:00

abstract：:Human endogenous retroviruses (HERVs) are the remnants of ancient germ cell infection by exogenous retroviruses and occupy up to 8% of the human genome. It has been suggested that HERV sequences have contributed to primate evolution by regulating the expression of cellular genes and mediating chromosome rearrangements...

journal_title：Journal of molecular evolution

authors： Macfarlane C,Simmonds P

更新日期：2004-11-01 00:00:00

abstract：:A cDNA encoding a new member of the gene family of major royal jelly proteins (MRJPs) from the honeybee, Apis mellifera, was isolated and sequenced. Royal jelly (RJ) is a secretion of the cephalic glands of nurse bees. The origin and biological function of the protein component (12.5%, w/w) of RJ is unknown. We show t...

journal_title：Journal of molecular evolution

authors： Albert S,Bhattacharya D,Klaudiny J,Schmitzová J,Simúth J

更新日期：1999-08-01 00:00:00

abstract：:In this article, we investigated the structural and dynamical evolutionary behaviour of a set of ten thioredoxin proteins as formed by three extant forms and seven resurrected ones in laboratory. Starting from the crystallographic structures, we performed all-atom molecular dynamics simulations and compare the traject...

journal_title：Journal of molecular evolution

authors： Del Galdo S,Alba J,Amadei A,D'Abramo M

更新日期：2019-07-01 00:00:00

abstract：:Fish protamines are highly specialized molecules which are responsible for chromatin condensation during the last stages of spermatogenesis (spermiogenesis). However, not all fish contain protamines in their sperm nuclei; rather, there seems to be a random distribution of protamines within this group. The origin of th...

journal_title：Journal of molecular evolution

authors： Saperas N,Ausio J,Lloris D,Chiva M

更新日期：1994-09-01 00:00:00

abstract：:Catalyzed by a family of enzymes called glycosyltransferases, glycosylation reactions are essential for the bioactivities of secondary metabolites such as antibiotics. Due to the special characters of antibiotic glycosyltransferases (AGts), antibiotics can function by attaching some unusual deoxy-sugars to their aglyc...

journal_title：Journal of molecular evolution

authors： Liang D,Qiao J

更新日期：2007-03-01 00:00:00

abstract：:Males of three inbred lines of Drosophila melanogaster were heat-shocked 90 min at 37 degrees C. The progenies from treated and untreated males mated with untreated females of the same line were checked for their chromosomal insertion patterns of various mobile elements by either in situ hybridization or Southern blot...

journal_title：Journal of molecular evolution

authors： Arnault C,Biémont C

更新日期：1989-05-01 00:00:00

abstract：:cDNA encoding the adhesive protein of the mussel Mytilus coruscus (Mcfp1) was isolated. The coding region encoded 848 amino acids (a.a.) comprising the 20-a.a. signal peptide, the 21-a.a. nonrepetitive linker, and the 805-a.a. repetitive domain. Although the first 204 nucleotides and the 3'-untranslated region of Mcfp...

journal_title：Journal of molecular evolution

authors： Inoue K,Takeuchi Y,Takeyama S,Yamaha E,Yamazaki F,Odo S,Harayama S

更新日期：1996-10-01 00:00:00

abstract：:Nucleotide sequences for the kappa-casein precursor proteins have been determined from the genomic DNAs or hair roots of the Ruminantia. The coding regions, exons 2, 3, and 4, were amplified separately via the three kinds of PCRs and then directly sequenced. The primers were designed from the sequence of bovine kappa-...

journal_title：Journal of molecular evolution

authors： Chikuni K,Mori Y,Tabata T,Saito M,Monma M,Kosugiyama M

更新日期：1995-12-01 00:00:00

abstract：:Two catalytic functions were required, minimally, for the appearance of DNA in evolution: a ribonucleotide reductase (RNR) and a reverse transcriptase (RT). If one accepts the explanatory strength of the RNA world model, it is clear that DNA molecules arose in the RNA world at some stage during the early evolution of ...

journal_title：Journal of molecular evolution

authors： León PE

更新日期：1998-08-01 00:00:00

abstract：:Calmodulin is a calcium-binding EF-hand protein that is an activator of many enzymes as well as ion pumps and channels. Due to its multiple targets and its central role in the cell, understanding the evolutionary history of calmodulin genes should provide insights into the origin of genetic complexity in eukaryotes. W...

journal_title：Journal of molecular evolution

authors： Karabinos A,Bhattacharya D

更新日期：2000-08-01 00:00:00

abstract：:Transbilayer diffusion of Mn2+ ions occurred in liposomes formed from dipalmitoyl-phosphatidylcholine or egg-yolk phosphatidylcholine and egg-yolk phosphatidate (molar ratio 2:1) containing DNA and DNase I within their aqueous compartments. Cation diffusion was demonstrated by the hydrolytic activity of DNase I, activ...

journal_title：Journal of molecular evolution

authors： Baeza I,Ibáñez M,Santiago JC,Argüello C,Wong C,Oró J

更新日期：1990-12-01 00:00:00

abstract：:The metabolic cycle of Saccharomyces cerevisiae consists of alternating oxidative (respiration) and reductive (glycolysis) energy-yielding reactions. The intracellular concentrations of amino acid precursors generated by these reactions oscillate accordingly, attaining maximal concentration during the middle of their ...

journal_title：Journal of molecular evolution

authors： de Bivort BL,Perlstein EO,Kunes S,Schreiber SL

更新日期：2009-05-01 00:00:00

abstract：:A general correlation between neural expression and negative charge in isozymes suggests charge represents an adaptation to the neural environment. Interestingly, a notable exception exists in teleost fish. Two cytosolic malate dehydrogenase (MDH) isozymes have different spatial expression patterns in certain fishes: ...

journal_title：Journal of molecular evolution

authors： Merrit TJ,Quattro M

更新日期：2003-03-01 00:00:00

abstract：:Catalyzed polymerization reactions represent a primary anabolic activity of all cells. It can be assumed that early cells carried out such reactions, in which macromolecular catalysts were encapsulated within some type of boundary membrane. In the experiments described here, we show that a template-independent RNA pol...

journal_title：Journal of molecular evolution

authors： Chakrabarti AC,Breaker RR,Joyce GF,Deamer DW

更新日期：1994-12-01 00:00:00

abstract：:Several distinct families of endogenous retroviruses exist in the genomes of primates. Most of them are remnants of ancient germ-line infections. The human endogenous retrovirus family HERV-K represents the unique known case of endogenous retrovirus that amplified in the human genome after the divergence of human and ...

journal_title：Journal of molecular evolution

authors： Costas J

更新日期：2001-09-01 00:00:00

abstract：:A systematic way of inferring evolutionary relatedness of microbial organisms from the oligopeptide content, i.e., frequency of amino acid K-strings in their complete proteomes, is proposed. The new method circumvents the ambiguity of choosing the genes for phylogenetic reconstruction and avoids the necessity of align...

journal_title：Journal of molecular evolution

authors： Qi J,Wang B,Hao BI

更新日期：2004-01-01 00:00:00

abstract：:LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamar...

journal_title：Journal of molecular evolution

authors： Boissinot S,Roos C,Furano AV

更新日期：2004-01-01 00:00:00

abstract：:Small heat shock proteins (sHSPs), as one subclass of molecular chaperones, are important for cells to protect proteins under stress conditions. Unlike the large HSPs (represented by Hsp60 and Hsp70), sHSPs are highly divergent in both primary sequences and oligomeric status, with their evolutionary relationships bein...

journal_title：Journal of molecular evolution

authors： Fu X,Jiao W,Chang Z

更新日期：2006-03-01 00:00:00

abstract：:In vitro selection of Zn(2+)-dependent RNA-cleaving DNAzymes with activity at 90 degrees C has yielded a diverse spool of selected sequences. The RNA cleavage efficiency was found in all cases to be specific for Zn(2+) over Pb(2+), Ca(2+), Cd(2+), Co(2+), Hg(2+), and Mg(2+). The Zn(2+)-dependent activity assay of the ...

journal_title：Journal of molecular evolution

authors： Nelson KE,Bruesehoff PJ,Lu Y

更新日期：2005-08-01 00:00:00

abstract：:Molecular domestication of a transposable element is defined as its functional recruitment by the host genome. To date, two independent events of molecular domestication of the P transposable element have been described: in the Drosophila obscura species group and in the Drosophila montium species subgroup. These P ne...

journal_title：Journal of molecular evolution

authors： Reiss D,Nouaud D,Ronsseray S,Anxolabéhère D

更新日期：2005-10-01 00:00:00

abstract：:Rooted phylogenetic trees for a total of 34 genes encoding the stimulatory (s alpha), inhibitory (i alpha), transducin (t alpha), Gx (x alpha), Gz (z alpha), G11 (alpha 11), G12 (alpha 12), G13 (alpha 13), G16 (alpha 16), Gq (q alpha), and other (o alpha) G protein alpha subunits have been constructed. The analysis sh...

journal_title：Journal of molecular evolution

authors： Yokoyama S,Starmer WT

更新日期：1992-09-01 00:00:00

abstract：:We present a new approach for analyzing directional mutation pressure and nucleotide content in protein-coding genes. Directional mutation pressure, the heterogenicity in the likelihood of different nucleotide substitutions, is used to explain the increasing or decreasing guanine-cytosine content (GC%) in DNA and is r...

journal_title：Journal of molecular evolution

authors： Jermiin LS,Graur D,Lowe RM,Crozier RH

更新日期：1994-08-01 00:00:00

abstract：:Recombination has been suggested to be an important factor for the genetic variation of bacterial genes, but few studies have dealt with intragenic recombination between the same or closely related species of cyanobacteria. Here we provide strong evidence for recombination in the microcystin synthetase (mcy) gene clus...

journal_title：Journal of molecular evolution

authors： Tanabe Y,Kaya K,Watanabe MM

更新日期：2004-06-01 00:00:00

abstract：:The activated dimonophosphate of 3'-deoxyadenosine (cordycepin) undergoes oligomerization to produce a new family of pyrophosphate-linked oligomers in which the average repeating unit involves a nine-atom structural group. The presence of a poly(U) template increases the relative yields of higher oligomers, although t...

journal_title：Journal of molecular evolution

authors： Visscher J,Schwartz AW

更新日期：1987-01-01 00:00:00

abstract：:An exhaustive computer-assisted analysis of the Moloney murine leukemia virus nucleotide sequence shows numerous deviations in the oligomeric distribution, suggesting three overlapping levels of a stepwise duplicative evolution. (1) The sequence fits the universal rule of TG/CT excess which has been proposed as the co...

journal_title：Journal of molecular evolution

authors： Laprevotte I

更新日期：1992-11-01 00:00:00

abstract：:The human S100 gene family encodes the EF-hand superfamily of calcium-binding proteins, with at least 14 family members clustered relatively closely together on chromosome 1q21. We have analyzed the most recently available genomic sequence of the human S100 gene cluster for evidence of tandem gene duplications during ...

journal_title：Journal of molecular evolution

authors： Kulski JK,Lim CP,Dunn DS,Bellgard M

更新日期：2003-04-01 00:00:00

abstract：:Introns are generally believed to evolve too rapidly and too erratically to be of much use in phylogenetic reconstructions. Few phylogenetically informative intron sequences are available, however, to ascertain the validity of this supposition. In the present study the supposition was tested on the example of the mamm...

journal_title：Journal of molecular evolution

authors： Kupfermann H,Satta Y,Takahata N,Tichy H,Klein J

更新日期：1999-06-01 00:00:00