Mo-MuLV nucleotide sequence exhibits three levels of oligomeric repetitions, suggesting a stepwise molecular evolution.

abstract：:This study dealt with the ability of non-denaturing gel electrophoresis to separate iso-1-cytochrome c with single amino acid replacements isolated from revertants of various cyc1 nonsense mutants of the yeast Saccharomyces cerevisiae. A total of 28 different iso-1-cytochromes c with single amino acid substitutions of...

journal_title：Journal of molecular evolution

authors： McLellan T,Sherman F

更新日期：1991-10-01 00:00:00

abstract：:Evolutionary divergence times can be inferred from molecular distances if a molecular clock can be assumed and if the substitution rate can be estimated. We present new evidence from relative rate tests that the rate of substitution at fourfold degenerate sites of nuclear genome-coding DNA is uniform in primate and ro...

journal_title：Journal of molecular evolution

authors： Easteal S,Herbert G

更新日期：1997-01-01 00:00:00

abstract：:The semen of many primate species coagulates into a mating plug believed to prevent the sperm of subsequent mating events from accessing the ova. The texture of the coagulum varies among species: from a semisoft mass in humans to a firm plug in chimpanzees. In humans, a component of the coagulum, semenogelin I, also i...

journal_title：Journal of molecular evolution

authors： Kingan SB,Tatar M,Rand DM

更新日期：2003-08-01 00:00:00

abstract：:The mitochondrial cytochrome b (cyt-b) gene is widely used in systematic studies to resolve divergences at many taxonomic levels. The present study focuses mainly on the utility of cyt-b as a molecular marker for inferring phylogenetic relationship at various levels within the fish family Cichlidae. A total of 78 taxa...

journal_title：Journal of molecular evolution

authors： Farias IP,Ortí G,Sampaio I,Schneider H,Meyer A

更新日期：2001-08-01 00:00:00

abstract：:Heterokonts are evolutionarily important as the most nutritionally diverse eukaryote supergroup and the most species-rich branch of the eukaryotic kingdom Chromista. Ancestrally photosynthetic/phagotrophic algae (mixotrophs), they include several ecologically important purely heterotrophic lineages, all grossly unders...

journal_title：Journal of molecular evolution

authors： Cavalier-Smith T,Chao EE

更新日期：2006-04-01 00:00:00

abstract：:Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnSOD2, were found to be organized in a tandem array within the Nosema bombycis ge...

journal_title：Journal of molecular evolution

authors： Xiang H,Pan G,Vossbrinck CR,Zhang R,Xu J,Li T,Zhou Z,Lu C,Xiang Z

更新日期：2010-12-01 00:00:00

abstract：:We present sequences of five novel RNase A superfamily ribonuclease genes of the bullfrog, Rana catesbeiana. All five genes encode ribonucleases that are similar to Onconase, a cytotoxic ribonuclease isolated from oocytes of R. pipiens. With amino acid sequence data from 14 ribonucleases from three Rana species (R. ca...

journal_title：Journal of molecular evolution

authors： Rosenberg HF,Zhang J,Liao YD,Dyer KD

更新日期：2001-07-01 00:00:00

abstract：:DNA methylation is one of the many hypotheses proposed to explain the observed deficiency in CpG dinucleotides in a variety of genomes covering a wide taxonomic distribution. Recent studies challenged the methylation hypothesis on empirical grounds. First, it cannot explain why the Mycoplasma genitalium genome exhibit...

journal_title：Journal of molecular evolution

authors： Xia X

更新日期：2003-01-01 00:00:00

abstract：:Intron-encoded U17 RNA is a member of the H/ACA box class of small nucleolar RNAs (snoRNAs) involved in ribosomal RNA (rRNA) maturation. U17 snoRNA shows typical characteristics of guide RNAs, which specify sites of pseudouridylation on the precursor rRNA (pre-rRNA). However, in spite of the presence of H and ACA boxe...

journal_title：Journal of molecular evolution

authors： Cervelli M,Cecconi F,Giorgi M,Annesi F,Oliverio M,Mariottini P

更新日期：2002-02-01 00:00:00

abstract：:A reaction which oligomerizes nucleotides under possible prebiotic conditions has been characterized. Nucleoside monophosphate in the presence of cyanamide at acid pH condenses to form dithymideine pyrophosphate and phosphodiester bonded compounds. Imidazole compounds and activated precursors such as nucleoside tripho...

journal_title：Journal of molecular evolution

authors： Odom DG,Brady JT

更新日期：1975-11-04 00:00:00

abstract：:In vitro selection of Zn(2+)-dependent RNA-cleaving DNAzymes with activity at 90 degrees C has yielded a diverse spool of selected sequences. The RNA cleavage efficiency was found in all cases to be specific for Zn(2+) over Pb(2+), Ca(2+), Cd(2+), Co(2+), Hg(2+), and Mg(2+). The Zn(2+)-dependent activity assay of the ...

journal_title：Journal of molecular evolution

authors： Nelson KE,Bruesehoff PJ,Lu Y

更新日期：2005-08-01 00:00:00

abstract：:To clarify the phylogenetic position of Vestimentifera (tube worms), 346-bp fragments of the elongation factor-1 alpha (EF-1 alpha) gene (939-1286 according to the numbering of the human gene) of a vestimentiferan, Lamellibrachia sp., a sternaspid polychaete, Sternaspis scutata, an earthworm, Pheretima sp., and a gast...

journal_title：Journal of molecular evolution

authors： Kojima S,Hashimoto T,Hasegawa M,Murata S,Ohta S,Seki H,Okada N

更新日期：1993-07-01 00:00:00

abstract：:In vitro run-off transcription by T7 RNA polymerase generates heterogeneous 3'-ends because the enzyme tends to add untemplated adenylates. To generate homogeneous 3'-termini, HDV ribozymes have been used widely. Their sequences are added to the 3'-terminus such that co-transcriptional self-cleavage generates homogene...

journal_title：Journal of molecular evolution

authors： Akoopie A,Müller UF

更新日期：2018-08-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) is the first enzyme in the polyamine biosynthetic pathway. We have studied the evolutionary history of the mammalian ODC mRNA, focusing on the rate of accumulation of sequence divergence within specific subregions of the molecule. The phylogenetic relationships among the mRNAs from severa...

journal_title：Journal of molecular evolution

authors： Johannes GJ,Berger FG

更新日期：1993-06-01 00:00:00

abstract：:The specificity of interaction of amino acids with triplets in the acceptor helix stem of tRNA was investigated by means of a statistical analysis of 1400 tRNA sequences. The imprint of a prototypic genetic code at position 3-5 of the acceptor helix was detected, but only for those major amino acids, glycine, alanine,...

journal_title：Journal of molecular evolution

authors： Möller W,Janssen GM

更新日期：1992-06-01 00:00:00

abstract：:The metabolic cycle of Saccharomyces cerevisiae consists of alternating oxidative (respiration) and reductive (glycolysis) energy-yielding reactions. The intracellular concentrations of amino acid precursors generated by these reactions oscillate accordingly, attaining maximal concentration during the middle of their ...

journal_title：Journal of molecular evolution

authors： de Bivort BL,Perlstein EO,Kunes S,Schreiber SL

更新日期：2009-05-01 00:00:00

abstract：:Twenty-seven protein sequence elements, six to nine amino acids long, were extracted from 15 phylogenetically diverse complete prokaryotic proteomes. The elements are present in all of these proteomes, with at least one copy each (omnipresent elements), and have presumably been conserved since the last universal commo...

journal_title：Journal of molecular evolution

authors： Sobolevsky Y,Frenkel ZM,Trifonov EN

更新日期：2007-12-01 00:00:00

abstract：:Protamine P1 genes have been sequenced by PCR amplification and direct DNA sequencing from 9 primates representing 5 major families, Cebidae (new world monkeys), Cercopithecidae (old world monkeys), Hylobatidae (gibbons), Pongidae (gorilla, orangutan, and chimpanzee), and Hominidae (human). In this recently diverged g...

journal_title：Journal of molecular evolution

authors： Retief JD,Winkfein RJ,Dixon GH,Adroer R,Queralt R,Ballabriga J,Oliva R

更新日期：1993-10-01 00:00:00

abstract：:Prediction of the thermodynamic behaviors of biomolecules at high temperature and pressure is fundamental to understanding the role of hydrothermal systems in the origin and evolution of life on the primitive Earth. However, available thermodynamic dataset for amino acids, essential components for life, cannot represe...

journal_title：Journal of molecular evolution

authors： Kitadai N

更新日期：2014-04-01 00:00:00

abstract：:Catalyzed by a family of enzymes called glycosyltransferases, glycosylation reactions are essential for the bioactivities of secondary metabolites such as antibiotics. Due to the special characters of antibiotic glycosyltransferases (AGts), antibiotics can function by attaching some unusual deoxy-sugars to their aglyc...

journal_title：Journal of molecular evolution

authors： Liang D,Qiao J

更新日期：2007-03-01 00:00:00

abstract：:The size and diversity of bacteriophage populations require methodologies to quantitatively study the landscape of phage differences. Statistical approaches are confronted with small genome sizes forbidding significant single-phage analysis, and comparative methods analyzing full phage genomes represent an alternative...

journal_title：Journal of molecular evolution

authors： Carbone A

更新日期：2008-03-01 00:00:00

abstract：:Alu elements are not distributed homogeneously throughout the human genome: old elements are preferentially found in the GC-rich parts of the genome, while young Alus are more often found in the GC-poor parts of the genome. The process giving rise to this differential distribution remains poorly understood. Here we in...

journal_title：Journal of molecular evolution

authors： Belle EM,Webster MT,Eyre-Walker A

更新日期：2005-03-01 00:00:00

abstract：:The finding that ribozymes can catalyze RNA chain elongation has led to the proposal that an early self-replicating system could have consisted of RNA alone. In such a chain elongation reaction, the Tetrahymena ribozyme was found to select 3',5'-linked substrates from a pool that contained a large molar excess of 2',5...

journal_title：Journal of molecular evolution

authors： Young B,Cech TR

更新日期：1989-12-01 00:00:00

abstract：:Characterization of sequences homologous to the Drosophila melanogaster gypsy transposable element was carried out in Drosophila subobscura (gypsyDS). They were found to be widely distributed among natural populations of this species. From Southern blot and in situ analyses, these sequences appear to be mobile in this...

journal_title：Journal of molecular evolution

authors： Alberola TM,de Frutos R

更新日期：1993-02-01 00:00:00

abstract：:Runs of identical amino acids encoded by triplet repeats (homopolymers) are components of numerous proteins, yet their role is poorly understood. Large numbers of homopolymers are present in the Drosophila melanogaster mastermind (mam) protein surrounding several unique charged amino acid clusters. Comparison of mam s...

journal_title：Journal of molecular evolution

authors： Newfeld SJ,Schmid AT,Yedvobnick B

更新日期：1993-11-01 00:00:00

abstract：:The DNA sequences of three members of the Alu family of repeated sequences located 5' to the chimpanzee alpha 2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimp...

journal_title：Journal of molecular evolution

authors： Sawada I,Willard C,Shen CK,Chapman B,Wilson AC,Schmid CW

更新日期：1985-01-01 00:00:00

abstract：:The complete or partial sequences of 47 E. coli ribosomal proteins described in the literature have been examined by computerized search and matching programs. In contrast to results previously reported by other investigators, sequence homologies were uncovered among some of these ribosomal proteins that are well beyo...

journal_title：Journal of molecular evolution

authors： Jue RA,Woodbury NW,Doolittle RF

更新日期：1980-05-01 00:00:00

abstract：:Drosophilidae is a large, widely distributed family of Diptera including 61 genera, of which Drosophila is the most representative. Drosophila feeding is part of the saprophytic trophic chain, because of its dependence upon decomposing organic matter. Many species have adapted to fermenting fruit feeding or to artific...

journal_title：Journal of molecular evolution

authors： Atrian S,Sánchez-Pulido L,Gonzàlez-Duarte R,Valencia A

更新日期：1998-08-01 00:00:00

abstract：:Since the genetic code first was determined, many have claimed that it is organized adaptively, so as to assign similar codons to similar amino acids. This claim has proved difficult to establish due to the absence of relevant comparative data on alternative primordial codes and of objective measures of amino acid exc...

journal_title：Journal of molecular evolution

authors： Stoltzfus A,Yampolsky LY

更新日期：2007-10-01 00:00:00

abstract：:Gamete-recognition proteins have been shown to evolve by positive selection in diverse organism groups, such as marine invertebrates and mammals, although underlying evolutionary mechanisms driving this rapid divergence are poorly understood. However, several hypotheses have been put forward to explain the observed pa...

journal_title：Journal of molecular evolution

authors： Berlin S,Qu L,Ellegren H

更新日期：2008-11-01 00:00:00