Classification of scorpion toxins according to amino acid composition and sequence.

abstract：:The human Rh blood group locus consists of two structurally related genes (D and CcEe) in Rh-positive haplotypes but a single gene (CcEe) in Rh-negative haplotypes. The genome of rhesus monkeys (Macaca mulatta), while not expressing any of the human Rh D, C, c, E, or e specificities, carries a Rh-like locus strongly r...

journal_title：Journal of molecular evolution

authors： Mouro I,Le Van Kim C,Cherif-Zahar B,Salvignol I,Blancher A,Cartron JP,Colin Y

更新日期：1994-02-01 00:00:00

abstract：:Friedreich ataxia is an autosomal recessive neurodegenerative disorder associated with a GAA repeat expansion in the first intron of the gene (FRDA) encoding a novel, highly conserved, 210 amino acid protein known as frataxin. Normal variation in repeat size was determined by analysis of more than 600 DNA samples from...

journal_title：Journal of molecular evolution

authors： Justice CM,Den Z,Nguyen SV,Stoneking M,Deininger PL,Batzer MA,Keats BJ

更新日期：2001-03-01 00:00:00

abstract：:Twenty-one different caprine and 13 ovine MHC-DRB exon 2 sequences were determined including part of the adjacent introns containing simple repetitive (gt)n(ga)m elements. The positions for highly polymorphic DRB amino acids vary slightly among ungulates and other mammals. From man and mouse to ungulates the basic (gt...

journal_title：Journal of molecular evolution

authors： Schwaiger FW,Weyers E,Epplen C,Brün J,Ruff G,Crawford A,Epplen JT

更新日期：1993-09-01 00:00:00

abstract：:MgtC is a virulence factor required for intramacrophage survival and growth in low Mg2+ medium in two pathogens that are not phylogenetically related, Salmonella typhimurium and Mycobacterium tuberculosis. In S. typhimurium, mgtC is carried by the SPI-3 pathogenicity island and hybridization studies have suggested tha...

journal_title：Journal of molecular evolution

authors： Blanc-Potard AB,Lafay B

更新日期：2003-10-01 00:00:00

abstract：:In this study, a new strategy for the selection of aptamers against small-molecule target was established using gold nanoparticles (AuNPs) as the separation matrix and Zinc(II)-Protoporphyrin IX (ZnPPIX) as the target molecule without the immobilization step due to the absorption of ssDNA on AuNPs. The progress of the...

journal_title：Journal of molecular evolution

authors： Li W,Luo Y,Gao T,Yang L,Wang J,Pei R

更新日期：2019-09-01 00:00:00

abstract：:Minerals may have played a significant role in chemical evolution. In the course of investigating the chemistry of phosphonoacetaldehyde (PAL), an analogue of glycolaldehyde phosphate, we have observed a striking case of catalysis by the layered hydroxide mineral hydrotalcite ([Mg2Al(OH)6][Cl.nH2O]). In neutral or mod...

journal_title：Journal of molecular evolution

authors： De Graaf RM,Visscher J,Xu Y,Arrhenius G,Schwartz AW

更新日期：1998-11-01 00:00:00

abstract：:We examined the nucleotide and amino acid sequence variation of the cytochrome c oxidase subunit II (COII) gene from 25 primates (4 hominoids, 8 Old World monkeys, 2 New World monkeys, 2 tarsiers, 7 lemuriforms, 2 lorisiforms). Marginal support was found for three phylogenetic conclusions: (1) sister-group relationshi...

journal_title：Journal of molecular evolution

authors： Adkins RM,Honeycutt RL

更新日期：1994-03-01 00:00:00

abstract：:Multiple phospholipase A2 (PLA2) isoenzymes found in a single snake venom induce a variety of pharmacological effects. These multiple forms are formed by gene duplication and accelerated evolution of exons. We examined the amino acid sequences of 127 snake venom PLA2 enzymes and their homologues to study in which loca...

journal_title：Journal of molecular evolution

authors： Kini RM,Chan YM

更新日期：1999-02-01 00:00:00

abstract：:The heterotrophic theory of the origin of life is the only proposal available with experimental support. This comes from the ease of prebiotic synthesis under strongly reducing conditions. The prebiotic synthesis of organic compounds by reduction of CO(2) to monomers used by the first organisms would also be considere...

journal_title：Journal of molecular evolution

authors： Lazcano A,Miller SL

更新日期：1999-10-01 00:00:00

abstract：:Fimbrial adhesins allow bacteria to interact with and attach to their environment. The bacteria possibly benefit from these interactions, but all external structures including adhesins also allow bacteria to be identified by other organisms. Thus adhesion molecules might be under multiple forms of selection including ...

journal_title：Journal of molecular evolution

authors： Peek AS,Souza V,Eguiarte LE,Gaut BS

更新日期：2001-02-01 00:00:00

abstract：:The transposable element mariner occurs widely in the melanogaster species group of Drosophila. However, in drosophilids outside of the melanogaster species group, sequences showing strong DNA hybridization with mariner are found only in the genus Zaprionus. The mariner sequence obtained from Zaprionus tuberculatus is...

journal_title：Journal of molecular evolution

authors： Maruyama K,Hartl DL

更新日期：1991-12-01 00:00:00

abstract：:Previous observations have indicated that Drosophila DNA contains a component that evolves so rapidly that it fails to hybridize between the DNAs of sibling species. To establish the reality of this component and study its properties, the fraction (about 20%) of Drosophila simulans (Dsim) DNA that fails to hybridize t...

journal_title：Journal of molecular evolution

authors： Werman SD,Davidson EH,Britten RJ

更新日期：1990-03-01 00:00:00

abstract：:Lepidoptera (comprised of butterflies and moths) is one of the largest groups of insects, including more than 160,000 described species. Chemoreception plays important roles in the adaptation of these species to a wide range of niches, e.g., plant hosts, egg-laying sites, and mates. This study investigated the molecul...

journal_title：Journal of molecular evolution

authors： Engsontia P,Sangket U,Chotigeat W,Satasook C

更新日期：2014-08-01 00:00:00

abstract：:Life is based on biopolymers that have the ability to replicate themselves. Here we consider how a self-replicating RNA system may have originated. We consider a reaction system in which polymerization is possible by the addition of an activated monomer to the end of a chain. We suppose that a small fraction of polyme...

journal_title：Journal of molecular evolution

authors： Wu M,Higgs PG

更新日期：2009-11-01 00:00:00

abstract：:Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...

journal_title：Journal of molecular evolution

authors： Wallis M

更新日期：2000-05-01 00:00:00

abstract：:Comparisons of the sequence divergence of three species of Hawaiian Drosophila have been made by hybridization of single-copy tracer DNA of each of the species with driver DNA from each species, and measurement of the average melting temperature (Tma) in a chaotropic solvent (2.4 M tetraethylammonium chloride) which m...

journal_title：Journal of molecular evolution

authors： Hunt JA,Hall TJ,Britten RJ

更新日期：1981-01-01 00:00:00

abstract：:Protamine P1 genes have been sequenced following PCR amplification from 11 mammals representing five major mammalian orders: Rodentia (rat and guinea pig), Carnivora (cat and bear), Proboscidea (elephant), Perissodactyla (horse), and Artiodactyla (camel, deer, elk, moose, and gazelle). The predicted amino acid sequenc...

journal_title：Journal of molecular evolution

authors： Queralt R,Adroer R,Oliva R,Winkfein RJ,Retief JD,Dixon GH

更新日期：1995-06-01 00:00:00

abstract：:Cosmochemical considerations suggest various potential sources for the accumulation of organic matter on Mars. However the Viking Molecular Analysis did not indicate any indigenous organic compounds on the surface of Mars. Their disappearance from the top layer is most likely caused by the combined action of the high ...

journal_title：Journal of molecular evolution

authors： Oró J,Holzer G

更新日期：1979-12-01 00:00:00

abstract：:We have identified and completely sequenced a novel plasmid isolated from the aphid Rhopalosiphum padi. Evidence which suggests that the plasmid occurs localized within the bacterial endosymbionts is presented. The plasmid contains the four genes that constitute the entire leucine operon. This fact makes it really uni...

journal_title：Journal of molecular evolution

authors： Bracho AM,Martínez-Torres D,Moya A,Latorre A

更新日期：1995-07-01 00:00:00

abstract：:Hydrophobins are small proteins, characterised by the presence of eight positionally conserved cysteine residues, and are present in all filamentous asco- and basidiomycetes. They are found on the outer surfaces of cell walls of hyphae and conidia, where they mediate interactions between the fungus and the environment...

journal_title：Journal of molecular evolution

authors： Seidl-Seiboth V,Gruber S,Sezerman U,Schwecke T,Albayrak A,Neuhof T,von Döhren H,Baker SE,Kubicek CP

更新日期：2011-04-01 00:00:00

abstract：:Domains are folded structures and evolutionary building blocks of protein molecules. Their three-dimensional atomic conformations, which define biological functions, can be coarse-grained into levels of a hierarchy. Here we build global dynamical models for the evolution of domains at fold and fold superfamily (FSF) l...

journal_title：Journal of molecular evolution

authors： Tal G,Boca SM,Mittenthal J,Caetano-Anollés G

更新日期：2016-05-01 00:00:00

abstract：:The problem of determining the minimal phylogenetic tree is discussed in relation to graph theory. It is shown that this problem is an example of the Steiner problem in graphs which is to connect a set of points by a minimal length network where new points can be added. There is no reported method of solving realistic...

journal_title：Journal of molecular evolution

authors： Foulds LR,Hendy MD,Penny D

更新日期：1979-07-18 00:00:00

abstract：:We report the nucleotide sequence of the single muscle actin gene of the sea urchin Strongylocentrotus purpuratus. Comparison of the protein-coding sequence of this muscle actin gene (pSpG28) with that of two linked sea urchin cytoskeletal actin genes (pSpG17 and CyIIa) reveals a region of exceptional sequence conserv...

journal_title：Journal of molecular evolution

authors： Crain WR Jr,Boshar MF,Cooper AD,Durica DS,Nagy A,Steffen D

更新日期：1987-01-01 00:00:00

abstract：:Using all currently predicted coding regions in the honeybee genome, a novel form of synonymous codon bias is presented that affects the usage of particular codons dependent on the surrounding nucleotides in the coding region. Nucleotides at the third codon site are correlated, dependent on their weak (adenine [A] or ...

journal_title：Journal of molecular evolution

authors： Cutler RW,Chantawannakul P

更新日期：2007-06-01 00:00:00

abstract：:Cot and chemical analysis show that the haploid genome size of Thermobia domestica is 3-4x10(9) nucleotide pairs. Of this DNA 33% is single copy sequences and 67% is repetitive sequences. The repetitive sequences are predominantly 300 nucleotides in length and are interspersed among the single copy sequences in a shor...

journal_title：Journal of molecular evolution

authors： French CK,Manning JE

更新日期：1980-08-01 00:00:00

abstract：:The evolution of ligand specificity underlies many important problems in biology, from the appearance of drug resistant pathogens to the re-engineering of substrate specificity in enzymes. In studying biomolecules, however, the contributions of macromolecular sequence to binding specificity can be obscured by other se...

journal_title：Journal of molecular evolution

authors： Held DM,Greathouse ST,Agrawal A,Burke DH

更新日期：2003-09-01 00:00:00

abstract：:We examined the cis- vs. trans-splicing status of the mitochondrial group II intron nad1i728 in 439 species (427 genera) of land plants, using both Southern hybridization results (for 416 species) and intron sequence data from the literature. A total of 164 species (157 genera), all angiosperms, was found to have a tr...

journal_title：Journal of molecular evolution

authors： Qiu YL,Palmer JD

更新日期：2004-07-01 00:00:00

abstract：:In order to assess the roles of gene conversion followed by natural selection and balancing selection for point mutations in polymorphisms at major histocompatibility complex (MHC) loci, DNA sequences of several mammalian taxa were analyzed. Synonymous and nonsynonymous diversities were estimated separately for the an...

journal_title：Journal of molecular evolution

authors： Ohta T

更新日期：1995-08-01 00:00:00

abstract：:The sequence of a cloned Anopheles stephensi gene showed 72% inferred amino acid identity with Drosophila melanogaster Dox-A2 and 93% with its putative ortholog in Anopheles gambiae. Dox-A2 is the reported but herein disputed structural locus for diphenol oxidase A2. Database searches identified Dox-A2 related gene se...

journal_title：Journal of molecular evolution

authors： Garvey CF,Malcolm CA

更新日期：2000-06-01 00:00:00

abstract：:Wild-type Escherichia coli utilizes glycerol aerobically through an inducible pathway mediated by an ATP-dependent kinase and a glycerol 3-phosphate dehydrogenase which is a flavoprotein. A mutant, strain ECL424, employing a novel pathway for glycerol utilization was isolated. The novel pathway is mediated by an NAD-l...

journal_title：Journal of molecular evolution

authors： Jin RZ,Tang JC,Lin EC

更新日期：1983-01-01 00:00:00