The paradox of MHC-DRB exon/intron evolution: alpha-helix and beta-sheet encoding regions diverge while hypervariable intronic simple repeats coevolve with beta-sheet codons.

abstract：:DNA clones have been isolated that span the complete mitochondrial (mt) genome of the dolphin, Cephalorhynchus commersonii. Hybridization experiments with purified primate mtDNA probes have established that there is close resemblance in the general organization of the dolphin mt genome and the terrestrial mammalian mt...

journal_title：Journal of molecular evolution

authors： Southern SO,Southern PJ,Dizon AE

更新日期：1988-12-01 00:00:00

abstract：:Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnSOD2, were found to be organized in a tandem array within the Nosema bombycis ge...

journal_title：Journal of molecular evolution

authors： Xiang H,Pan G,Vossbrinck CR,Zhang R,Xu J,Li T,Zhou Z,Lu C,Xiang Z

更新日期：2010-12-01 00:00:00

abstract：:The diversity of functional genes and the related processes are important issues for conservation biology. This is especially relevant for populations that have suffered from demographic reduction as a consequence of the processes of postglacial colonization. In this perspective, the aims of the present study are (1) ...

journal_title：Journal of molecular evolution

authors： Girard P,Angers B

更新日期：2011-08-01 00:00:00

abstract：:We have studied the metal-ion catalysis of a number of reactions of the isomers of ImpGpG on a poly(C) template. In the absence of a catalytic metal ion, oligomers at least up to (pG)20 are obtained from the ImpGpG isomers in a 1-methylimidazole buffer. The Pb2+ ion improves the yield of longer oligomers and changes s...

journal_title：Journal of molecular evolution

authors： Lohrmann R,Bridson PK,Orgel LE

更新日期：1981-01-01 00:00:00

abstract：:Nucleotide polymorphisms in two North American balsam poplars (Populus trichocarpa Torr. & Gray and P. balsamifera L.; section Tacamahaca), and one Eurasian aspen (P. tremula L.; section Populus) were compared using nine loci involved in defense, stress response, photoperiodism, freezing tolerance, and housekeeping. N...

journal_title：Journal of molecular evolution

authors： Ismail M,Soolanayakanahally RY,Ingvarsson PK,Guy RD,Jansson S,Silim SN,El-Kassaby YA

更新日期：2012-06-01 00:00:00

abstract：:Proteins are commonly used as molecular targets against pathogens such as viruses and bacteria. However, pathogens can evolve rapidly permitting their populations to increase in protein diversity over time and thus escape to the activity of a molecular therapy. Subsequently, in order to design more durable and robust ...

journal_title：Journal of molecular evolution

authors： Arenas M

更新日期：2020-08-01 00:00:00

abstract：:The accuracies and efficiencies of three different methods of making phylogenetic trees from gene frequency data were examined by using computer simulation. The methods examined are UPGMA, Farris' (1972) method, and Tateno et al.'s (1982) modified Farris method. In the computer simulation eight species (or populations...

journal_title：Journal of molecular evolution

authors： Nei M,Tajima F,Tateno Y

更新日期：1983-01-01 00:00:00

abstract：:Actin is a highly conserved protein although many isoforms exist. In vertebrates and insects the different actin isoforms can be grouped by their amino acid sequence and tissue-specific gene expression into muscle and nonmuscle actins, suggesting that the different actins may have a functional significance. We ask her...

journal_title：Journal of molecular evolution

authors： Mounier N,Sparrow JC

更新日期：1997-01-01 00:00:00

abstract：:The usage of synonymous codons and the frequencies of amino acids were investigated in the complete genome of the bacterium Thermotoga maritima using a multivariate statistical approach. The GC3 content of each gene was the most prominent source of variation of codon usage. Surprisingly the usage of UGU and UGC (synon...

journal_title：Journal of molecular evolution

authors： Zavala A,Naya H,Romero H,Musto H

更新日期：2002-05-01 00:00:00

abstract：:The study of genetic evolution within the context of adaptive radiations offers insights to genes and selection pressures that result in rapid morphological change. Cichlid fishes are very species-rich and variable in coloration, behavior, and morphology, and so provide a classical model system for studying the geneti...

journal_title：Journal of molecular evolution

authors： Fan S,Elmer KR,Meyer A

更新日期：2011-08-01 00:00:00

abstract：:Gamete-recognition proteins have been shown to evolve by positive selection in diverse organism groups, such as marine invertebrates and mammals, although underlying evolutionary mechanisms driving this rapid divergence are poorly understood. However, several hypotheses have been put forward to explain the observed pa...

journal_title：Journal of molecular evolution

authors： Berlin S,Qu L,Ellegren H

更新日期：2008-11-01 00:00:00

abstract：:Marine mussels of the genus Mytilus have two types of mitochondrial DNA with separate paternal and maternal inheritance. Females are homoplasmic for an F genome that is transmitted to all offspring, whereas males are heteroplasmic for this F genome and for a highly diverged (> 20%) M genome that is transmitted only to...

journal_title：Journal of molecular evolution

authors： Quesada H,Stuckas H,Skibinski DO

更新日期：2003-01-01 00:00:00

abstract：:The efficiency of obtaining the correct tree by the maximum likelihood method (Felsenstein 1981) for inferring trees from DNA sequence data was compared with trees obtained by distance methods. It was shown that the maximum likelihood method is superior to distance methods in the efficiency particularly when the evolu...

journal_title：Journal of molecular evolution

authors： Hasegawa M,Kishino H,Saitou N

更新日期：1991-05-01 00:00:00

abstract：:This study investigated the evolution of a transition metal ion-binding cluster ([H--X--X--X--H](n); Tx) in the alternatively spliced NH(2)-terminal variable region of avian pectoral muscle troponin T (TnT). Encoded by avian fast skeletal muscle TnT-specific P exons, Tx-like structures were expressed in the breast mus...

journal_title：Journal of molecular evolution

authors： Jin JP,Samanez RA

更新日期：2001-02-01 00:00:00

abstract：:A+T content, phylogenetic relationships, codon usage, evolutionary rates, and ratio of synonymous versus non-synonymous substitutions have been studied in partial sequences of the atpD and aroQ/pheA genes of primary ( Buchnera) and secondary symbionts of aphids and a set of selected non-symbiotic bacteria, belonging t...

journal_title：Journal of molecular evolution

authors： Moya A,Latorre A,Sabater-Muñoz B,Silva FJ

更新日期：2002-08-01 00:00:00

abstract：:In this study, the molecular population genetics of the orangutan's alpha-2 globin (HBA2) gene were investigated in order to test for the action of natural selection. Haplotypes from 28 orangutan chromosomes were collected from a 1.46-kilobase region of the alpha-2 globin locus. While many aspects of the data were con...

journal_title：Journal of molecular evolution

authors： Steiper ME,Wolfe ND,Karesh WB,Kilbourn AM,Bosi EJ,Ruvolo M

更新日期：2005-03-01 00:00:00

abstract：:RNA has a myriad of biological roles in contemporary life. We use the RNA paradigm for genotype-phenotype mappings to study the evolution of multiple coding in dependence to mutation rates. We study three different one-to-many genotype-phenotype mappings which have the potential to encode the information for multiple ...

journal_title：Journal of molecular evolution

authors： de Boer FK,Hogeweg P

更新日期：2014-12-01 00:00:00

abstract：:A reaction which oligomerizes nucleotides under possible prebiotic conditions has been characterized. Nucleoside monophosphate in the presence of cyanamide at acid pH condenses to form dithymideine pyrophosphate and phosphodiester bonded compounds. Imidazole compounds and activated precursors such as nucleoside tripho...

journal_title：Journal of molecular evolution

authors： Odom DG,Brady JT

更新日期：1975-11-04 00:00:00

abstract：:A cDNA encoding a new member of the gene family of major royal jelly proteins (MRJPs) from the honeybee, Apis mellifera, was isolated and sequenced. Royal jelly (RJ) is a secretion of the cephalic glands of nurse bees. The origin and biological function of the protein component (12.5%, w/w) of RJ is unknown. We show t...

journal_title：Journal of molecular evolution

authors： Albert S,Bhattacharya D,Klaudiny J,Schmitzová J,Simúth J

更新日期：1999-08-01 00:00:00

abstract：:The relaxin (RLN) and insulin-like (INSL) gene family is a group of genes involved in a variety of physiological roles that includes bone formation, testicular descent, trophoblast development, and cell differentiation. This family appears to have expanded in vertebrates relative to non-vertebrate chordates, but the r...

journal_title：Journal of molecular evolution

authors： Hoffmann FG,Opazo JC

更新日期：2011-01-01 00:00:00

abstract：:At least two polymorphic Alu insertions have been previously identified and characterized within the class I region of the major histocompatibility complex (MHC). We have identified another two new polymorphic Alu insertions, AluyHJ and AluyHF, located near HLA-J and HLA-F, respectively, within the a block of the MHC....

journal_title：Journal of molecular evolution

authors： Dunn DS,Naruse T,Inoko H,Kulski JK

更新日期：2002-12-01 00:00:00

abstract：:We examined the cis- vs. trans-splicing status of the mitochondrial group II intron nad1i728 in 439 species (427 genera) of land plants, using both Southern hybridization results (for 416 species) and intron sequence data from the literature. A total of 164 species (157 genera), all angiosperms, was found to have a tr...

journal_title：Journal of molecular evolution

authors： Qiu YL,Palmer JD

更新日期：2004-07-01 00:00:00

abstract：:Recombination has been suggested to be an important factor for the genetic variation of bacterial genes, but few studies have dealt with intragenic recombination between the same or closely related species of cyanobacteria. Here we provide strong evidence for recombination in the microcystin synthetase (mcy) gene clus...

journal_title：Journal of molecular evolution

authors： Tanabe Y,Kaya K,Watanabe MM

更新日期：2004-06-01 00:00:00

abstract：:Heterokonts are evolutionarily important as the most nutritionally diverse eukaryote supergroup and the most species-rich branch of the eukaryotic kingdom Chromista. Ancestrally photosynthetic/phagotrophic algae (mixotrophs), they include several ecologically important purely heterotrophic lineages, all grossly unders...

journal_title：Journal of molecular evolution

authors： Cavalier-Smith T,Chao EE

更新日期：2006-04-01 00:00:00

abstract：:Throughout history, remote archipelagos have repeatedly been designated natural laboratories to study evolutionary processes. The extensive, geographically structured, morphological variation within Galápagos' Opuntia cacti has been presumed to be another example of how such processes shape diversity. However, recent ...

journal_title：Journal of molecular evolution

authors： Helsen P,Verdyck P,Van Dongen S

更新日期：2011-03-01 00:00:00

abstract：:Characterization of sequences homologous to the Drosophila melanogaster gypsy transposable element was carried out in Drosophila subobscura (gypsyDS). They were found to be widely distributed among natural populations of this species. From Southern blot and in situ analyses, these sequences appear to be mobile in this...

journal_title：Journal of molecular evolution

authors： Alberola TM,de Frutos R

更新日期：1993-02-01 00:00:00

abstract：:Cytochrome proteins perform a broad spectrum of biological functions ranging from oxidative metabolism to electron transport and are thus essential to all organisms. The b-type cytochrome proteins bind heme noncovalently, are expressed in many different forms and are localized to various cellular compartments. We repo...

journal_title：Journal of molecular evolution

authors： Kula ME,Allay ER,Rozek CE

更新日期：1995-10-01 00:00:00

abstract：:Amino acid substitution models represent substitution rates among amino acids during the evolution. The models play an important role in analyzing protein sequences, especially inferring phylogenies. The rapid evolution of flaviviruses is expanding the threat in public health. A number of models have been estimated fo...

journal_title：Journal of molecular evolution

authors： Le TK,Vinh LS

更新日期：2020-07-01 00:00:00

abstract：:We have determined the nucleotide sequence of the 26S large subunit (LSU) rRNA genes for two Tetrahymena species, T. thermophila and T. pyriformis. The inferred rRNA sequences are presented in their most probable secondary structures based on compensatory mutations, energy, and conservation criteria. The majority of t...

journal_title：Journal of molecular evolution

authors： Engberg J,Nielsen H,Lenaers G,Murayama O,Fujitani H,Higashinakagawa T

更新日期：1990-06-01 00:00:00

abstract：:The major histocompatibility complex (MHC) consists of polymorphic frozen blocks (PFBs) that are linked to form megabase haplotypes. These blocks consist of polymorphic sequences and define regions where recombination appears to be inhibited. We have been able to show, using a highly polymorphic sequence centromeric o...

journal_title：Journal of molecular evolution

authors： Gaudieri S,Leelayuwat C,Tay GK,Townend DC,Dawkins RL

更新日期：1997-07-01 00:00:00