Abstract:
:The heterotrophic theory of the origin of life is the only proposal available with experimental support. This comes from the ease of prebiotic synthesis under strongly reducing conditions. The prebiotic synthesis of organic compounds by reduction of CO(2) to monomers used by the first organisms would also be considered an heterotrophic origin. Autotrophy means that the first organisms biosynthesized their cell constituents as well as assembling them. Prebiotic synthetic pathways are all different from the biosynthetic pathways of the last common ancestor (LCA). The steps leading to the origin of the metabolic pathways are closer to prebiotic chemistry than to those in the LCA. There may have been different biosynthetic routes between the prebiotic and the LCAs that played an early role in metabolism but have disappeared from extant organisms. The semienzymatic theory of the origin of metabolism proposed here is similar to the Horowitz hypothesis but includes the use of compounds leaking from preexisting pathways as well as prebiotic compounds from the environment.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Lazcano A,Miller SLkeywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
424-31issue
4eissn
0022-2844issn
1432-1432pii
JMES99-111journal_volume
49pub_type
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:1975-08-05 00:00:00
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
pub_type: 杂志文章,评审
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:Journal of molecular evolution
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更新日期:2002-03-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:1995-10-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF01731583
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更新日期:2001-12-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF01732473
更新日期:1976-03-29 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:1999-04-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:1999-12-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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