The bacteriophage lambda attachment site in wild strains of Escherichia coli.

abstract：:The Pten gene was initially identified in humans as a tumor suppressor. It has since been shown to play important roles in the control of cell size, cell motility, apoptosis, and organ size, and it has also been implicated in aging. Pten is highly conserved among organisms as diverse as nematodes, insects, and vertebr...

journal_title：Journal of molecular evolution

authors： Baudry E,Desmadril M,Werren JH

更新日期：2006-06-01 00:00:00

abstract：:Bacterial family C DNA polymerases (DNA pol IIIs), the major chromosomal replicative enzymes, have been provisionally classified based on primary sequences and domain structures into three classes: class I (Escherichia coli DNA pol C-type), class II (Bacillus subtilis DNA pol C-type), and class III (cyanobacterial DNA...

journal_title：Journal of molecular evolution

authors： Huang YP,Ito J

更新日期：1999-06-01 00:00:00

abstract：:Eight human short tandem repeat polymorphisms (STRs) also known as microsatellites-DYS19, DYS388, DYS390, DYS391, DYS392, DYS393, DYS389I, and DYS389II, mapping in the Y chromosome-were analyzed in two Iberian samples (Basques and Catalans). Allele frequency distributions showed significant differences only for DYS392...

journal_title：Journal of molecular evolution

authors： Pérez-Lezaun A,Calafell F,Seielstad M,Mateu E,Comas D,Bosch E,Bertranpetit J

更新日期：1997-09-01 00:00:00

abstract：:Analysis of occurrence of simple amino acid repeats in large ensemble of prokaryotic and eukaryotic sequences reveals that nearly all amino acids found in the repeats belong to those which have in their codon repertoires aggressively expanding triplets, all of three known pathologically expanding classes GCU (GCU, CUG...

journal_title：Journal of molecular evolution

authors： Koren Z,Trifonov EN

更新日期：2011-02-01 00:00:00

abstract：:Heterokonts are evolutionarily important as the most nutritionally diverse eukaryote supergroup and the most species-rich branch of the eukaryotic kingdom Chromista. Ancestrally photosynthetic/phagotrophic algae (mixotrophs), they include several ecologically important purely heterotrophic lineages, all grossly unders...

journal_title：Journal of molecular evolution

authors： Cavalier-Smith T,Chao EE

更新日期：2006-04-01 00:00:00

abstract：:Compared with the X chromosome, the mammalian Y chromosome is considerably diminished in size and has lost most of its ancestral genes during evolution. Interestingly, for the X-degenerate region on the Y chromosome, human has retained all 16 genes, while chimpanzee has lost 4 of the 16 genes since the divergence of t...

journal_title：Journal of molecular evolution

authors： Goto H,Peng L,Makova KD

更新日期：2009-02-01 00:00:00

abstract：:We report the sequence of A/B.L1, a tightly linked pair of genes from the A and B chorion families in Bombyx mori. Comparison with the previously characterized A/B.L11 and A/B.L12 pairs from the same species reveals moderate sequence divergence, which is clearly nonuniform. Although the average divergence of A/B.L12 f...

journal_title：Journal of molecular evolution

authors： Tsitilou SG,Kafatos FC

更新日期：1989-11-01 00:00:00

abstract：:EcoRI restriction of the B. nigra rDNA recombinants, isolated from a lambda genomic library, showed that the 3.9-kb fragment corresponded to the Intergenic Spacer (IGS), which was sequenced and found to be 3,928 bp in size. Sequence and dot-matrix analyses showed that the organization of the B. nigra rDNA IGS was typi...

journal_title：Journal of molecular evolution

authors： Bhatia S,Singh Negi M,Lakshmikumaran M

更新日期：1996-11-01 00:00:00

abstract：:This study investigated the evolution of a transition metal ion-binding cluster ([H--X--X--X--H](n); Tx) in the alternatively spliced NH(2)-terminal variable region of avian pectoral muscle troponin T (TnT). Encoded by avian fast skeletal muscle TnT-specific P exons, Tx-like structures were expressed in the breast mus...

journal_title：Journal of molecular evolution

authors： Jin JP,Samanez RA

更新日期：2001-02-01 00:00:00

abstract：:Selection pressures on proteins are usually measured by comparing homologous nucleotide sequences (Zuckerkandl and Pauling 1965). Recently we introduced a novel method, termed volatility, to estimate selection pressures on proteins on the basis of their synonymous codon usage (Plotkin and Dushoff 2003; Plotkin et al. ...

journal_title：Journal of molecular evolution

authors： Plotkin JB,Dushoff J,Desai MM,Fraser HB

更新日期：2006-11-01 00:00:00

abstract：:It has been suggested that inorganic membranes were forerunners of organic membranes at the origin of life. Such membranes, interposed between alkaline fluid in submarine vents and the more acidic Hadean ocean, were thought to house inorganic molecular machines. H+ flowed down the pH gradient (ΔpH) from ocean to vent ...

journal_title：Journal of molecular evolution

authors： Jackson JB

更新日期：2017-08-01 00:00:00

abstract：:The codon assignment of the quasi-universal genetic code can be assumed to have resulted from the evolutionary pressures that prevailed when the code was still evolving. Here, we review studies of the structure of the genetic code based on optimization models. We also review studies that, from the structure of the cod...

journal_title：Journal of molecular evolution

authors： Jestin JL,Kempf A

更新日期：2009-11-01 00:00:00

abstract：:We have performed DNA-DNA hybridization experiments among several species of Drosophila using the evolutionarily conserved portion of the genome representing sequences coding for amino acids of proteins. This was done by using as tracer, radioactively labeled complementary DNA that was reverse transcribed from adult m...

journal_title：Journal of molecular evolution

authors： Caccone A,Gleason JM,Powell JR

更新日期：1992-02-01 00:00:00

abstract：:The metabolic cycle of Saccharomyces cerevisiae consists of alternating oxidative (respiration) and reductive (glycolysis) energy-yielding reactions. The intracellular concentrations of amino acid precursors generated by these reactions oscillate accordingly, attaining maximal concentration during the middle of their ...

journal_title：Journal of molecular evolution

authors： de Bivort BL,Perlstein EO,Kunes S,Schreiber SL

更新日期：2009-05-01 00:00:00

abstract：:The evolutionary relationships among arthropod hemocyanins and insect hexamerins were investigated. A multiple sequence alignment of 12 hemocyanin and 31 hexamerin subunits was constructed and used for studying sequence conservation and protein phylogeny. Although hexamerins and hemocyanins belong to a highly divergen...

journal_title：Journal of molecular evolution

authors： Burmester T,Massey HC Jr,Zakharkin SO,Benes H

更新日期：1998-07-01 00:00:00

abstract：:Phylogenetic hypotheses of muscle actin evolution are significantly different when a sea urchin is used as a representative echinoderm than when a sea star is used. While sea urchin muscle actins support an echinoderm-chordate sister relationship, sea star sequences suggest that echinoderm muscle actins are convergent...

journal_title：Journal of molecular evolution

authors： White ME,Crother BI

更新日期：2000-02-01 00:00:00

abstract：:Langley and Fitch (1974, 1976) have shown that the pattern of nucleotide substitutions in proteins is inconsistent with a Poisson process with constant rate. From this they conclude that the rate is temporally heterogeneous. It is pointed out in this note that a process which is temporally homogeneous but not a Poisso...

journal_title：Journal of molecular evolution

authors： Gillespie JH,Langley CH

更新日期：1979-06-08 00:00:00

abstract：:Darwinian theory requires that mutations be produced in a nonanticipatory manner; it is nonetheless consistent to suggest that mutations that have repeatedly led to nonviable phenotypes would be introduced less frequently than others-if under appropriate genetic control. Immunoglobulins produced during infection acqui...

journal_title：Journal of molecular evolution

authors： Cowell LG,Kim HJ,Humaljoki T,Berek C,Kepler TB

更新日期：1999-07-01 00:00:00

abstract：:Drosophilidae is a large, widely distributed family of Diptera including 61 genera, of which Drosophila is the most representative. Drosophila feeding is part of the saprophytic trophic chain, because of its dependence upon decomposing organic matter. Many species have adapted to fermenting fruit feeding or to artific...

journal_title：Journal of molecular evolution

authors： Atrian S,Sánchez-Pulido L,Gonzàlez-Duarte R,Valencia A

更新日期：1998-08-01 00:00:00

abstract：:Phylogenetic relationships among eight species of the Drosophila buzzatii species complex (D. mulleri subgroup; D. repleta species group) and D. hamatofila were determined by sequencing the mitochondrial cytochrome oxidase subunit I, II, and III genes. The species examined included members of the martensis cluster (D....

journal_title：Journal of molecular evolution

authors： Spicer GS

更新日期：1995-12-01 00:00:00

abstract：:We characterized the organization of mitochondrial genes from a diverse range of hymenopterans. Of the 21 taxa characterized, 12 had distinct, derived organizations. Some rearrangements were consistent with the duplication-random loss mechanism, while others were not. Local inversions were relatively common, i.e., rea...

journal_title：Journal of molecular evolution

authors： Dowton M,Castro LR,Campbell SL,Bargon SD,Austin AD

更新日期：2003-05-01 00:00:00

abstract：:We examined the codon usages in well-conserved and less-well-conserved regions of vertebrate protein genes and found them to be similar. Despite this similarity, there is a statistically significant decrease in codon bias in the less-well-conserved regions. Our analysis suggests that although those codon changes initi...

journal_title：Journal of molecular evolution

authors： Lipman DJ,Wilbur WJ

更新日期：1984-01-01 00:00:00

abstract：:Many proteins exhibit sequence periodicity, often correlated with a visible structural periodicity. The statistical significance of such periodicity can be assessed by means of a chi-squared-based test, with significance thresholds being calculated from shuffled sequences. Comparison of the complete proteomes of 45 sp...

journal_title：Journal of molecular evolution

authors： Gatherer D,McEwan NR

更新日期：2005-04-01 00:00:00

abstract：:We studied the genomic organization of Hox genes in Atlantic salmon (Salmo salar) and made comparisons to that in rainbow trout (Oncorhynchus mykiss), another member of the family Salmonidae. We used these two species to test the hypothesis that the Hox genes would provide evidence for a fourth round of duplication (4...

journal_title：Journal of molecular evolution

authors： Moghadam HK,Ferguson MM,Danzmann RG

更新日期：2005-11-01 00:00:00

abstract：:Heat induces a number of premutational lesions (for example, the deamination of cytosine to uracil) in DNA and RNA. These kinds of errors occur in resting as well as replicating polynucleotides. However, an increase in temperature also raises the probability of copying error occurring in nucleic acids because of incre...

journal_title：Journal of molecular evolution

authors： Reanney DC,Pressing J

更新日期：1984-01-01 00:00:00

abstract：:Fish protamines are highly specialized molecules which are responsible for chromatin condensation during the last stages of spermatogenesis (spermiogenesis). However, not all fish contain protamines in their sperm nuclei; rather, there seems to be a random distribution of protamines within this group. The origin of th...

journal_title：Journal of molecular evolution

authors： Saperas N,Ausio J,Lloris D,Chiva M

更新日期：1994-09-01 00:00:00

abstract：:Tests for positive selection have mostly been developed to look for diversifying selection where change away from the current amino acid is often favorable. However, in many cases we are interested in directional selection where there is a shift toward specific amino acids, resulting in increased fitness in the specie...

journal_title：Journal of molecular evolution

authors： Thiltgen G,Dos Reis M,Goldstein RA

更新日期：2017-01-01 00:00:00

abstract：:An exhaustive computer-assisted analysis of the Moloney murine leukemia virus nucleotide sequence shows numerous deviations in the oligomeric distribution, suggesting three overlapping levels of a stepwise duplicative evolution. (1) The sequence fits the universal rule of TG/CT excess which has been proposed as the co...

journal_title：Journal of molecular evolution

authors： Laprevotte I

更新日期：1992-11-01 00:00:00

abstract：:Molecular domestication of a transposable element is defined as its functional recruitment by the host genome. To date, two independent events of molecular domestication of the P transposable element have been described: in the Drosophila obscura species group and in the Drosophila montium species subgroup. These P ne...

journal_title：Journal of molecular evolution

authors： Reiss D,Nouaud D,Ronsseray S,Anxolabéhère D

更新日期：2005-10-01 00:00:00

abstract：:We have cloned and sequenced a protamine gene from the chum salmon (Oncorhynchus keta). This gene sequence is highly homologous to one found in the rainbow trout (Salmo gairdneri), including the conservation of two structurally different repetitive elements. One of these repeats resembles a nonviral retroposon and the...

journal_title：Journal of molecular evolution

authors： Moir RD,Dixon GH

更新日期：1988-01-01 00:00:00