DNA polymerase C of the thermophilic bacterium Thermus aquaticus: classification and phylogenetic analysis of the family C DNA polymerases.

abstract：:Throughout history, remote archipelagos have repeatedly been designated natural laboratories to study evolutionary processes. The extensive, geographically structured, morphological variation within Galápagos' Opuntia cacti has been presumed to be another example of how such processes shape diversity. However, recent ...

journal_title：Journal of molecular evolution

authors： Helsen P,Verdyck P,Van Dongen S

更新日期：2011-03-01 00:00:00

abstract：:All modern mammals contain a distinctive, highly repeated (> or = 50,000 members) family of long interspersed repeated DNA called the L1 (LINE 1) family. While the modern L1 families were derived from a common ancestor that predated the mammalian radiation approximately 80 million years ago, most of the members of the...

journal_title：Journal of molecular evolution

authors： Pascale E,Liu C,Valle E,Usdin K,Furano AV

更新日期：1993-01-01 00:00:00

abstract：:Rooted phylogenetic trees for a total of 34 genes encoding the stimulatory (s alpha), inhibitory (i alpha), transducin (t alpha), Gx (x alpha), Gz (z alpha), G11 (alpha 11), G12 (alpha 12), G13 (alpha 13), G16 (alpha 16), Gq (q alpha), and other (o alpha) G protein alpha subunits have been constructed. The analysis sh...

journal_title：Journal of molecular evolution

authors： Yokoyama S,Starmer WT

更新日期：1992-09-01 00:00:00

abstract：:Hypothetical Products from Noncoding Frames (i.e., HyPNoFs) are hypothetical, not-coded proteins, translated from alternate reading frames (i.e., coding + 1 and coding + 2) of cDNAs. HyPNoFs of CD4, PKC, oncostatin, bcl-2 proto-oncogene, tumor suppressor p53, cystic fibrosis transmembrane regulator (CFTR), and tumor n...

journal_title：Journal of molecular evolution

authors： Facchiano A

更新日期：1995-06-01 00:00:00

abstract：:Analysis of mitochondrial DNAs (mtDNAs) from parthenogenetic lizards of the Heteronotia binoei complex with restriction enzymes revealed an approximately 5-kb addition present in all 77 individuals. Cleavage site mapping suggested the presence of a direct tandem duplication spanning the 16S and 12S rRNA genes, the con...

journal_title：Journal of molecular evolution

authors： Zevering CE,Moritz C,Heideman A,Sturm RA

更新日期：1991-11-01 00:00:00

abstract：:Group I introns are mobile RNA enzymes (ribozymes) that encode conserved primary and secondary structures required for autocatalysis. The group I intron that interrupts the tRNA-Leu gene in cyanobacteria and plastids is remarkable because it is the oldest known intervening sequence and may have been present in the com...

journal_title：Journal of molecular evolution

authors： Simon D,Fewer D,Friedl T,Bhattacharya D

更新日期：2003-12-01 00:00:00

abstract：:Nucleotide polymorphisms in two North American balsam poplars (Populus trichocarpa Torr. & Gray and P. balsamifera L.; section Tacamahaca), and one Eurasian aspen (P. tremula L.; section Populus) were compared using nine loci involved in defense, stress response, photoperiodism, freezing tolerance, and housekeeping. N...

journal_title：Journal of molecular evolution

authors： Ismail M,Soolanayakanahally RY,Ingvarsson PK,Guy RD,Jansson S,Silim SN,El-Kassaby YA

更新日期：2012-06-01 00:00:00

abstract：:The kinetics of synonymous codon change and species divergence is described in a matrix formalism that is equally applicable to all levels of codon degeneracy and all levels of codon or nucleotide bias. Based on the formalism it is possible to calculate the sum of all synonymous substitution rate constants from the ob...

journal_title：Journal of molecular evolution

authors： Berg OG

更新日期：1995-09-01 00:00:00

abstract：:The study of genetic evolution within the context of adaptive radiations offers insights to genes and selection pressures that result in rapid morphological change. Cichlid fishes are very species-rich and variable in coloration, behavior, and morphology, and so provide a classical model system for studying the geneti...

journal_title：Journal of molecular evolution

authors： Fan S,Elmer KR,Meyer A

更新日期：2011-08-01 00:00:00

abstract：:We outline a method for estimating quantitatively the influence of point mutations and selection on the frequencies of codons and amino acids. We show how the mutation rate, i.e., the rate of amino acid replacement due to point mutation, can be affected by the codon usage as well as by the rates of the involved base e...

journal_title：Journal of molecular evolution

authors： Frömmel C,Holzhütter HG

更新日期：1984-01-01 00:00:00

abstract：:The evolution of ligand specificity underlies many important problems in biology, from the appearance of drug resistant pathogens to the re-engineering of substrate specificity in enzymes. In studying biomolecules, however, the contributions of macromolecular sequence to binding specificity can be obscured by other se...

journal_title：Journal of molecular evolution

authors： Held DM,Greathouse ST,Agrawal A,Burke DH

更新日期：2003-09-01 00:00:00

abstract：:The mammalian defensin molecule is a short, highly cationic peptide cytotoxic to both microbial and mammalian cells which is cleaved from a precursor including a signal peptide and a highly anionic propiece. A phylogenetic analysis of 28 complete sequences from five mammalian species (mouse, rat, guinea pig, rabbit, a...

journal_title：Journal of molecular evolution

authors： Hughes AL,Yeager M

更新日期：1997-06-01 00:00:00

abstract：:Characterization of sequences homologous to the Drosophila melanogaster gypsy transposable element was carried out in Drosophila subobscura (gypsyDS). They were found to be widely distributed among natural populations of this species. From Southern blot and in situ analyses, these sequences appear to be mobile in this...

journal_title：Journal of molecular evolution

authors： Alberola TM,de Frutos R

更新日期：1993-02-01 00:00:00

abstract：:Recombination has been suggested to be an important factor for the genetic variation of bacterial genes, but few studies have dealt with intragenic recombination between the same or closely related species of cyanobacteria. Here we provide strong evidence for recombination in the microcystin synthetase (mcy) gene clus...

journal_title：Journal of molecular evolution

authors： Tanabe Y,Kaya K,Watanabe MM

更新日期：2004-06-01 00:00:00

abstract：:The metabolic cycle of Saccharomyces cerevisiae consists of alternating oxidative (respiration) and reductive (glycolysis) energy-yielding reactions. The intracellular concentrations of amino acid precursors generated by these reactions oscillate accordingly, attaining maximal concentration during the middle of their ...

journal_title：Journal of molecular evolution

authors： de Bivort BL,Perlstein EO,Kunes S,Schreiber SL

更新日期：2009-05-01 00:00:00

abstract：:Several algae that were previously classified in the phylum Xanthophyta (yellow-green algae) were assigned in 1971 to a new phylum, Eustigmatophyta. It was anticipated that the number of algae reclassified to Eustigmatophyta would increase. However, due to the fact that the morphological characteristics that segregate...

journal_title：Journal of molecular evolution

authors： Ehara M,Hayashi-Ishimaru Y,Inagaki Y,Ohama T

更新日期：1997-08-01 00:00:00

abstract：:Explicit evaluation of the accuracy and power of maximum likelihood and Bayesian methods for detecting site-specific positive Darwinian selection presents a challenge because selective consequences of single amino acid changes are generally unknown. We exploited extensive molecular and functional characterization of a...

journal_title：Journal of molecular evolution

authors： Cavatorta JR,Savage AE,Yeam I,Gray SM,Jahn MM

更新日期：2008-11-01 00:00:00

abstract：:The relaxin (RLN) and insulin-like (INSL) gene family is a group of genes involved in a variety of physiological roles that includes bone formation, testicular descent, trophoblast development, and cell differentiation. This family appears to have expanded in vertebrates relative to non-vertebrate chordates, but the r...

journal_title：Journal of molecular evolution

authors： Hoffmann FG,Opazo JC

更新日期：2011-01-01 00:00:00

abstract：:The pentose phosphate cycle is considered as a major source of NADPH and pentose needed for nucleic acid biosynthesis. 6-Phosphogluconate dehydrogenase (6PGD), an enzyme participating in this cycle, catalyzes the oxidative decarboxylation of 6PGD to ribulose 5-phosphate with the subsequent release of CO2 and the reduc...

journal_title：Journal of molecular evolution

authors： Goulielmos GN,Eliopoulos E,Loukas M,Tsakas S

更新日期：2004-09-01 00:00:00

abstract：:The mitochondrial cytochrome b (cyt-b) gene is widely used in systematic studies to resolve divergences at many taxonomic levels. The present study focuses mainly on the utility of cyt-b as a molecular marker for inferring phylogenetic relationship at various levels within the fish family Cichlidae. A total of 78 taxa...

journal_title：Journal of molecular evolution

authors： Farias IP,Ortí G,Sampaio I,Schneider H,Meyer A

更新日期：2001-08-01 00:00:00

abstract：:Frugivorous and nectarivorous bats rely largely on hepatic glycogenesis and glycogenolysis for postprandial blood glucose disposal and maintenance of glucose homeostasis during short time starvation, respectively. The glycogen synthase 2 encoded by the Gys2 gene plays a critical role in liver glycogen synthesis. To te...

journal_title：Journal of molecular evolution

authors： Qian Y,Fang T,Shen B,Zhang S

更新日期：2014-01-01 00:00:00

abstract：:By a chromosome walking strategy the DNA region from Methanococcus vannielii flanking the genes for protein synthesis elongation factor (EF) 1 alpha and EF-2 was cloned and sequenced. A gene organization of 5' - beta' - open reading frame (ORF) 1 - ORF2 - S12 - S7 - EF-2 - EF-1 alpha - S10 - ORF3 - ORF4 - 3' was found...

journal_title：Journal of molecular evolution

authors： Lechner K,Heller G,Böck A

更新日期：1989-07-01 00:00:00

abstract：:The monotremes, the duck-billed platypus and the echidnas, are characterized by a number of unique morphological characteristics, which have led to the common belief that they represent the living survivors of an ancestral stock of mammals. Analysis of new data from the complete mitochondrial (mt) genomes of a second ...

journal_title：Journal of molecular evolution

authors： Janke A,Magnell O,Wieczorek G,Westerman M,Arnason U

更新日期：2002-01-01 00:00:00

abstract：:The nucleotide sequences of 5S rRNAs from three protozoa, Bresslaua vorax, Euplotes woodruffi and Chlamydomonas sp. have been determined and aligned together with the sequences of 12 protozoa species including unicellular green algae already reported by the authors and others. Using this alignment, a phylogenic tree o...

journal_title：Journal of molecular evolution

authors： Kumazaki T,Hori H,Osawa S

更新日期：1983-01-01 00:00:00

abstract：:Cytochrome proteins perform a broad spectrum of biological functions ranging from oxidative metabolism to electron transport and are thus essential to all organisms. The b-type cytochrome proteins bind heme noncovalently, are expressed in many different forms and are localized to various cellular compartments. We repo...

journal_title：Journal of molecular evolution

authors： Kula ME,Allay ER,Rozek CE

更新日期：1995-10-01 00:00:00

abstract：:The sequences of the adenylate kinase gene (adk) and the RecA gene (recA) were determined from the same isolates of Neisseria gonorrhoeae, N. meningitidis, N. lactamica, N. polysaccharea, N. cinerea, N. mucosa, N. pharyngis var. flava, N. flavescens, and N. animalis. The patterns of sequence divergence observed at adk...

journal_title：Journal of molecular evolution

authors： Feil E,Zhou J,Maynard Smith J,Spratt BG

更新日期：1996-12-01 00:00:00

abstract：:Several studies in Drosophila have shown a paucity of male-biased genes (i.e., genes that express higher in males than in females) on the X chromosome. Dosage compensation (DC) is a regulatory mechanism of gene expression triggered in males that hypertranscribes the X-linked genes to the level of transcription in fema...

journal_title：Journal of molecular evolution

authors： Gallach M,Betrán E

更新日期：2016-05-01 00:00:00

abstract：:Phylogenetic hypotheses of muscle actin evolution are significantly different when a sea urchin is used as a representative echinoderm than when a sea star is used. While sea urchin muscle actins support an echinoderm-chordate sister relationship, sea star sequences suggest that echinoderm muscle actins are convergent...

journal_title：Journal of molecular evolution

authors： White ME,Crother BI

更新日期：2000-02-01 00:00:00

abstract：:The core histone genes of Saccharomyces cerevisiae are arranged as duplicate nonallelic sets of specifically paired genes. The identity of structural organization between the duplicated gene pairs would have its simplest evolutionary origin in the duplication of a complete locus in a single event. In such a case, the ...

journal_title：Journal of molecular evolution

authors： Smith MM

更新日期：1987-01-01 00:00:00

abstract：:Many eubacteria contain an ATP-dependent protease complex, which is built by multiple copies of the HslV and HslU proteins and is therefore called HslVU. HslU proteins are AAA + ATPases, while HslV proteins are proteases that show highly significant similarity to beta subunits of proteasomes. Therefore, the HslVU comp...

journal_title：Journal of molecular evolution

authors： Ruiz-González MX,Marín I

更新日期：2006-10-01 00:00:00