Role of everlasting triplet expansions in protein evolution.

abstract：:HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1. Since then, numerous sequences of HMG-box-containing HMG proteins and other DNA-binding proteins from several species have become avai...

journal_title：Journal of molecular evolution

authors： Griess EA,Rensing SA,Grasser KD,Maier UG,Feix G

更新日期：1993-08-01 00:00:00

abstract：:The phylogeny of the creatine kinase (CK, EC 2.7.3.2) isozyme loci and their differential tissue expressions were determined for representatives of 65 families of vertebrates, with emphasis on the fishes. The transition from the single creatine kinase locus, characteristic of certain echinoderms, to the two creatine k...

journal_title：Journal of molecular evolution

authors： Fisher SE,Whitt GS

更新日期：1978-10-27 00:00:00

abstract：:Seven new Italian and two new British HTLV-II isolates were obtained from injecting drug users and the entire long terminal repeat (LTR) region was sequenced. Restriction analysis showed that all the Italian isolates are of the IIb subtype, whereas the British isolates are of the IIa subtype. To understand whether the...

journal_title：Journal of molecular evolution

authors： Salemi M,Vandamme AM,Gradozzi C,Van Laethem K,Cattaneo E,Taylor G,Casoli C,Goubau P,Desmyter J,Bertazzoni U

更新日期：1998-05-01 00:00:00

abstract：:A systematic way of inferring evolutionary relatedness of microbial organisms from the oligopeptide content, i.e., frequency of amino acid K-strings in their complete proteomes, is proposed. The new method circumvents the ambiguity of choosing the genes for phylogenetic reconstruction and avoids the necessity of align...

journal_title：Journal of molecular evolution

authors： Qi J,Wang B,Hao BI

更新日期：2004-01-01 00:00:00

abstract：:Protamine P1 genes have been sequenced following PCR amplification from 11 mammals representing five major mammalian orders: Rodentia (rat and guinea pig), Carnivora (cat and bear), Proboscidea (elephant), Perissodactyla (horse), and Artiodactyla (camel, deer, elk, moose, and gazelle). The predicted amino acid sequenc...

journal_title：Journal of molecular evolution

authors： Queralt R,Adroer R,Oliva R,Winkfein RJ,Retief JD,Dixon GH

更新日期：1995-06-01 00:00:00

abstract：:Adenosine 5'-phosphoramidates form when solutions containing adenosine 5'-polyphosphates pnA (n greater than or equal to 3) or P1, P2-diadenosine 5'-diphosphate and amines are allowed to dry out. Mg ions catalyze these reactions. We have studied systems containing ammonia, imidazole, glycine, ethylenediamine and hista...

journal_title：Journal of molecular evolution

authors： Lohrmann R

更新日期：1977-11-25 00:00:00

abstract：:Orphan genes, lacking detectable homologs in outgroup species, typically represent 10-30% of eukaryotic genomes. Efforts to find the source of these young genes indicate that de novo emergence from non-coding DNA may in part explain their prevalence. Here, we investigate the roots of orphan gene emergence in the Droso...

journal_title：Journal of molecular evolution

authors： Heames B,Schmitz J,Bornberg-Bauer E

更新日期：2020-05-01 00:00:00

abstract：:Copia is a retrotransposon that appears to be distributed widely among the Drosophilidae subfamily. Evolutionary analyses of regulatory regions have indicated that the Copia retrotransposon evolved through both positive and purifying selection, and that horizontal transfer (HT) could also explain its patchy distributi...

journal_title：Journal of molecular evolution

authors： de Setta N,Van Sluys MA,Capy P,Carareto CM

更新日期：2011-03-01 00:00:00

abstract：:The attachment site (attlambda) of bacteriophage lambda was examined in wild strains of Escherichia coli. Although the att region is non-coding, the DNA sequence was invariant in the 13 strains examined. Two other non-coding regions showed nine changes, all associated with a single strain. In four of 33 strains, seque...

journal_title：Journal of molecular evolution

authors： Kuhn J,Campbell A

更新日期：2001-12-01 00:00:00

abstract：:This study investigated the evolution of a transition metal ion-binding cluster ([H--X--X--X--H](n); Tx) in the alternatively spliced NH(2)-terminal variable region of avian pectoral muscle troponin T (TnT). Encoded by avian fast skeletal muscle TnT-specific P exons, Tx-like structures were expressed in the breast mus...

journal_title：Journal of molecular evolution

authors： Jin JP,Samanez RA

更新日期：2001-02-01 00:00:00

abstract：:Two catalytic functions were required, minimally, for the appearance of DNA in evolution: a ribonucleotide reductase (RNR) and a reverse transcriptase (RT). If one accepts the explanatory strength of the RNA world model, it is clear that DNA molecules arose in the RNA world at some stage during the early evolution of ...

journal_title：Journal of molecular evolution

authors： León PE

更新日期：1998-08-01 00:00:00

abstract：:Phylogenetic relationships among eight species of the Drosophila buzzatii species complex (D. mulleri subgroup; D. repleta species group) and D. hamatofila were determined by sequencing the mitochondrial cytochrome oxidase subunit I, II, and III genes. The species examined included members of the martensis cluster (D....

journal_title：Journal of molecular evolution

authors： Spicer GS

更新日期：1995-12-01 00:00:00

abstract：:In the plant chloroplast genome the codon usage of the highly expressed psbA gene is unique and is adapted to the tRNA population, probably due to selection for translation efficiency. In this study the role of selection on codon usage in each of the fully sequenced chloroplast genomes, in addition to Chlamydomonas re...

journal_title：Journal of molecular evolution

authors： Morton BR

更新日期：1998-04-01 00:00:00

abstract：:Several studies in Drosophila have shown a paucity of male-biased genes (i.e., genes that express higher in males than in females) on the X chromosome. Dosage compensation (DC) is a regulatory mechanism of gene expression triggered in males that hypertranscribes the X-linked genes to the level of transcription in fema...

journal_title：Journal of molecular evolution

authors： Gallach M,Betrán E

更新日期：2016-05-01 00:00:00

abstract：:Previously we suggested that four proteins including aldolase and triose phosphate isomerase (TPI) evolved with approximately constant rates over long periods covering the whole animal phyla. The constant rates of aldolase and TPI evolution were reexamined based on three different models for estimating evolutionary di...

journal_title：Journal of molecular evolution

authors： Nikoh N,Iwabe N,Kuma K,Ohno M,Sugiyama T,Watanabe Y,Yasui K,Shi-cui Z,Hori K,Shimura Y,Miyata T

更新日期：1997-07-01 00:00:00

abstract：:At least two polymorphic Alu insertions have been previously identified and characterized within the class I region of the major histocompatibility complex (MHC). We have identified another two new polymorphic Alu insertions, AluyHJ and AluyHF, located near HLA-J and HLA-F, respectively, within the a block of the MHC....

journal_title：Journal of molecular evolution

authors： Dunn DS,Naruse T,Inoko H,Kulski JK

更新日期：2002-12-01 00:00:00

abstract：:RNA editing affecting chloroplast and mitochondrial genomes has been identified in all major clades of land plants. The frequency of edited sites varies greatly between lineages but hornworts represent an extreme in propensity for editing in both their chloroplast and mitochondrial genomes. cDNA sequences from seven t...

journal_title：Journal of molecular evolution

authors： Duff RJ,Moore FB

更新日期：2005-11-01 00:00:00

abstract：:Antibody binding site are formed by six hypervariable regions or complementarity determining regions (CDRs). The CDRs, three from the heavy chain and three from the light chain, are known as hypervariable segments and provide a surface complementary to that of the epitope. In recent work it was found that the amino ac...

journal_title：Journal of molecular evolution

authors： Vargas-Madrazo E,Lara-Ochoa F,Jiménez-Montaño M

更新日期：1994-01-01 00:00:00

abstract：:Using all currently predicted coding regions in the honeybee genome, a novel form of synonymous codon bias is presented that affects the usage of particular codons dependent on the surrounding nucleotides in the coding region. Nucleotides at the third codon site are correlated, dependent on their weak (adenine [A] or ...

journal_title：Journal of molecular evolution

authors： Cutler RW,Chantawannakul P

更新日期：2007-06-01 00:00:00

abstract：:We described previously a family of dispersed palindromic sequences highly repeated in Escherichia coli and Salmonella typhimurium genomes. These sequences, called PU (palindromic units), are located outside structural genes. We report here observations suggesting that PU may have a role in bacterial speciation. ...

journal_title：Journal of molecular evolution

authors： Gilson E,Perrin D,Saurin W,Hofnung M

更新日期：1987-01-01 00:00:00

abstract：:The observed and expected frequencies of occurrence of microsatellites in the yeast Saccharomyces cerevisiae were investigated. In all cases, the observed frequencies exceeded the expected ones. In contrast to predictions by Messier et al. (1996), there is no critical number of repeats beyond which the observed freque...

journal_title：Journal of molecular evolution

authors： Pupko T,Graur D

更新日期：1999-03-01 00:00:00

abstract：:DNA methylation is one of the many hypotheses proposed to explain the observed deficiency in CpG dinucleotides in a variety of genomes covering a wide taxonomic distribution. Recent studies challenged the methylation hypothesis on empirical grounds. First, it cannot explain why the Mycoplasma genitalium genome exhibit...

journal_title：Journal of molecular evolution

authors： Xia X

更新日期：2003-01-01 00:00:00

abstract：:Analysis of cDNAs from Macrovipera lebetina transmediterranea (Mlt) and Echis ocellatus (Eo) venom gland libraries encoding disintegrins argued strongly for a common ancestry of the messengers of short disintegrins and those for precursors of dimeric disintegrin chains. We now report the sequence analysis of disintegr...

journal_title：Journal of molecular evolution

authors： Bazaa A,Juárez P,Marrakchi N,Bel Lasfer Z,El Ayeb M,Harrison RA,Calvete JJ,Sanz L

更新日期：2007-02-01 00:00:00

abstract：:The present work deals with the processes involved in the abiogenic polycondensation of nucleotides adsorbed on the clay mineral kaolinite under the action of ultraviolet (UV) radiation. The dependence of the yield of synthesis products on irradiation dose was studied. The maximum yield corresponds to a 6-h exposure. ...

journal_title：Journal of molecular evolution

authors： Strigunkova TF,Lavrentiev GA,Otroshchenko VA

更新日期：1986-01-01 00:00:00

abstract：:We have determined the genomic structure of an integrin beta-subunit gene from the coral, Acropora millepora. The coding region of the gene contains 26 introns, spaced relatively uniformly, and this is significantly more than have been found in any integrin beta-subunit genes from higher animals. Twenty-five of the 26...

journal_title：Journal of molecular evolution

authors： Schmitt DM,Brower DL

更新日期：2001-12-01 00:00:00

abstract：:Nucleotide sequences for the kappa-casein precursor proteins have been determined from the genomic DNAs or hair roots of the Ruminantia. The coding regions, exons 2, 3, and 4, were amplified separately via the three kinds of PCRs and then directly sequenced. The primers were designed from the sequence of bovine kappa-...

journal_title：Journal of molecular evolution

authors： Chikuni K,Mori Y,Tabata T,Saito M,Monma M,Kosugiyama M

更新日期：1995-12-01 00:00:00

abstract：:Microsatellite DNA sequences have become the dominant source of nuclear genetic markers for most applications. It is important to investigate the basis of variation between alleles and to know if current assumptions about the mechanisms of microsatellite mutation (that is to say, variations involving simple changes in...

journal_title：Journal of molecular evolution

authors： Grimaldi MC,Crouau-Roy B

更新日期：1997-03-01 00:00:00

abstract：:To clarify the phylogenetic position of Vestimentifera (tube worms), 346-bp fragments of the elongation factor-1 alpha (EF-1 alpha) gene (939-1286 according to the numbering of the human gene) of a vestimentiferan, Lamellibrachia sp., a sternaspid polychaete, Sternaspis scutata, an earthworm, Pheretima sp., and a gast...

journal_title：Journal of molecular evolution

authors： Kojima S,Hashimoto T,Hasegawa M,Murata S,Ohta S,Seki H,Okada N

更新日期：1993-07-01 00:00:00

abstract：:There has been considerable discussion in recent years on the evolution of the tandemly repeated multigene families, since some organisms show a concerted model whereas others show a birth-and-death model. This controversial subject extends to several species of fish. In this study, three species of the Sparidae famil...

journal_title：Journal of molecular evolution

authors： Merlo MA,Cross I,Manchado M,Cárdenas S,Rebordinos L

更新日期：2013-03-01 00:00:00

abstract：:In this study, the molecular population genetics of the orangutan's alpha-2 globin (HBA2) gene were investigated in order to test for the action of natural selection. Haplotypes from 28 orangutan chromosomes were collected from a 1.46-kilobase region of the alpha-2 globin locus. While many aspects of the data were con...

journal_title：Journal of molecular evolution

authors： Steiper ME,Wolfe ND,Karesh WB,Kilbourn AM,Bosi EJ,Ruvolo M

更新日期：2005-03-01 00:00:00