Gene conversions may obscure actin gene family relationships.

abstract：:A comparison of mitochondrial DNA sequences was undertaken for two genes among orangutans from Borneo and Sumatra. The distribution of haplotypes among 42 individuals for NADH dehydrogenease subunit 3 and 39 individuals for cytochrome B was used to infer population structure. The haplotypes among all Bornean orangutan...

journal_title：Journal of molecular evolution

authors： Muir CC,Galdikas BM,Beckenbach AT

更新日期：2000-11-01 00:00:00

abstract：:The mitochondrial genome of yeast (S. cerevisiae or S. carlsbergensis) appears to be formed by 60-70 genetic units, each one of which is formed by (1) a GC-rich sequence, possibly having a regulatory role; (2) a gene, and (3) an AT-rich spacer, which probably is not transcribed. Recombination in this genome appears to...

journal_title：Journal of molecular evolution

authors： Bernardi G

更新日期：1976-12-31 00:00:00

abstract：:The neutral theory of molecular evolution states that most mutations are deleterious or neutral. It results that the evolutionary rate of a given position in an alignment is a function of the level of constraint acting on this position. Inferring evolutionary rates from a set of aligned sequences is hence a powerful m...

journal_title：Journal of molecular evolution

authors： Dutheil J

更新日期：2008-09-01 00:00:00

abstract：:An emergent problem in the study of pathogen evolution is our ability to determine the extent to which their rapidly evolving genomes recombine. Such information is necessary and essential for locating pathogenicity loci using association studies, and it also directs future screening, therapeutic and vaccination strat...

journal_title：Journal of molecular evolution

authors： Greenspan G,Geiger D,Gotch F,Bower M,Patterson S,Nelson M,Gazzard B,Stebbing J

更新日期：2004-03-01 00:00:00

abstract：:The alpha-esterase cluster of D. melanogaster contains 11 esterase genes dispersed over 60 kb. Embedded in the cluster are two unrelated open reading frames that have sequence similarity with genes encoding ubiquitin-conjugating enzyme and tropomyosin. The esterase amino acid sequences show 37-66% identity with one an...

journal_title：Journal of molecular evolution

authors： Robin C,Russell RJ,Medveczky KM,Oakeshott JG

更新日期：1996-09-01 00:00:00

abstract：:Sequence comparisons of 14 distinct MHC class I cDNA clones isolated from species representing the three major taxonomic lineages of Felidae (domestic cat lineage, ocelot lineage, and pantherine lineage) revealed that feline MHC class I alleles have highly mosaic structures with short polymorphic sequence motifs that ...

journal_title：Journal of molecular evolution

authors： Yuhki N,O'Brien SJ

更新日期：1994-07-01 00:00:00

abstract：:Computational analysis of the hypothetical open reading frame MJ0236 from Methanococcus jannaschii reveals its membership to a family of bacterial and eukaryotic proteins, predicted to be the HMP-P kinases involved in thiamin biosyntheis (ThiD). The eukaryotic members of this family contain a C-terminal extension simi...

journal_title：Journal of molecular evolution

authors： Ouzounis CA,Kyrpides NC

更新日期：1997-12-01 00:00:00

abstract：:The entire mitochondrial DNA control region (mtDNA D-loop) was sequenced in the seven extant species of Alectoris partridges. The D-loop length is very conserved (1155 +/- 2 nucleotides), and substitution rates are lower than for the mitochondrial cytochrome b gene of the same species, on average. Comparative analyses...

journal_title：Journal of molecular evolution

authors： Randi E,Lucchini V

更新日期：1998-10-01 00:00:00

abstract：:Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnSOD2, were found to be organized in a tandem array within the Nosema bombycis ge...

journal_title：Journal of molecular evolution

authors： Xiang H,Pan G,Vossbrinck CR,Zhang R,Xu J,Li T,Zhou Z,Lu C,Xiang Z

更新日期：2010-12-01 00:00:00

abstract：:Evaporation of a solution of thymidine plus either the exo or the endo diastereomer of uridine cyclic 2',3'-O, O-phosphorothioate (U greater than p(S) in 1,2-diaminoethane hydrochloride buffer gave the 2',5' and 3',5' isomers of (P-thio) uridylylthymidine (Up(S)dT) in a ratio of 1:2 with a combined yield of about 20%....

journal_title：Journal of molecular evolution

authors： Usher DA,Yee D

更新日期：1979-11-01 00:00:00

abstract：:Domains are folded structures and evolutionary building blocks of protein molecules. Their three-dimensional atomic conformations, which define biological functions, can be coarse-grained into levels of a hierarchy. Here we build global dynamical models for the evolution of domains at fold and fold superfamily (FSF) l...

journal_title：Journal of molecular evolution

authors： Tal G,Boca SM,Mittenthal J,Caetano-Anollés G

更新日期：2016-05-01 00:00:00

abstract：:Insertions and deletions of entire codons have recently been discovered as a mechanism by which B cells, in addition to conventional base substitution, evolve the antibodies produced by their immunoglobulin genes. These events frequently seem to involve repetitive sequence motifs in the antibody-encoding genes, and it...

journal_title：Journal of molecular evolution

authors： Lantto J,Ohlin M

更新日期：2002-03-01 00:00:00

abstract：:Adenosine 5'-phosphoramidates form when solutions containing adenosine 5'-polyphosphates pnA (n greater than or equal to 3) or P1, P2-diadenosine 5'-diphosphate and amines are allowed to dry out. Mg ions catalyze these reactions. We have studied systems containing ammonia, imidazole, glycine, ethylenediamine and hista...

journal_title：Journal of molecular evolution

authors： Lohrmann R

更新日期：1977-11-25 00:00:00

abstract：:A 6.0-kb DNA fragment from Gorilla gorilla including the 5' part of the beta-globin gene and about 4.5 kb of its upstream flanking region was cloned and sequenced. The sequence was compared to the human, chimpanzee, and macaque delta-beta intergenic region. This analysis reveals four tandemly repeated sequences (RS), ...

journal_title：Journal of molecular evolution

authors： Perrin-Pecontal P,Gouy M,Nigon VM,Trabuchet G

更新日期：1992-01-01 00:00:00

abstract：:It is known that globin genes contain three exons with the middle exon coding for a four-helical supersecondary structure responsible for heme binding. Since this portion of the globin peptide chain can be structurally superimposed onto the cytochrome c and cytochrome b5 chains (Argos and Rossmann 1979), it can be inf...

journal_title：Journal of molecular evolution

authors： Argos P,Rossmann MG

更新日期：1980-12-01 00:00:00

abstract：:Introns are generally believed to evolve too rapidly and too erratically to be of much use in phylogenetic reconstructions. Few phylogenetically informative intron sequences are available, however, to ascertain the validity of this supposition. In the present study the supposition was tested on the example of the mamm...

journal_title：Journal of molecular evolution

authors： Kupfermann H,Satta Y,Takahata N,Tichy H,Klein J

更新日期：1999-06-01 00:00:00

abstract：:At least two polymorphic Alu insertions have been previously identified and characterized within the class I region of the major histocompatibility complex (MHC). We have identified another two new polymorphic Alu insertions, AluyHJ and AluyHF, located near HLA-J and HLA-F, respectively, within the a block of the MHC....

journal_title：Journal of molecular evolution

authors： Dunn DS,Naruse T,Inoko H,Kulski JK

更新日期：2002-12-01 00:00:00

abstract：:A fundamental paradox motivates the study of plant mitochondrial genomics: the mutation rate is very low (lower than in the nucleus) but the rearrangement rate is high. A landmark paper published in Journal of Molecular Evolution in 1988 established these facts and revealed the paradox. Jeffrey Palmer and Laura Herbon...

journal_title：Journal of molecular evolution

authors： Christensen AC

更新日期：2021-01-24 00:00:00

abstract：:The human Rh blood group locus consists of two structurally related genes (D and CcEe) in Rh-positive haplotypes but a single gene (CcEe) in Rh-negative haplotypes. The genome of rhesus monkeys (Macaca mulatta), while not expressing any of the human Rh D, C, c, E, or e specificities, carries a Rh-like locus strongly r...

journal_title：Journal of molecular evolution

authors： Mouro I,Le Van Kim C,Cherif-Zahar B,Salvignol I,Blancher A,Cartron JP,Colin Y

更新日期：1994-02-01 00:00:00

abstract：:Phylogenetic relationships of 25 mammalian species representing 17 of the 18 eutherian orders were examined using DNA sequences from a 1.2-kb region of the 5' end of exon 1 of the single-copy nuclear gene known as interphotoreceptor retinoid binding protein (IRBP). A wide variety of methods of analysis of the DNA sequ...

journal_title：Journal of molecular evolution

authors： Stanhope MJ,Smith MR,Waddell VG,Porter CA,Shivji MS,Goodman M

更新日期：1996-08-01 00:00:00

abstract：:Oligonucleotide cataloguing has been used to characterize a number of 5S RNA species from various Procaryotes. Such catalogs can be used to establish certain and detailed phylogenetic relationships among organisms. Confining attention at present to four Families of Procaryotes, theEnterobacteriaceae, theBacillaceae, t...

journal_title：Journal of molecular evolution

authors： Sogin SJ,Sogin ML,Woese CR

更新日期：1972-06-01 00:00:00

abstract：:A general correlation between neural expression and negative charge in isozymes suggests charge represents an adaptation to the neural environment. Interestingly, a notable exception exists in teleost fish. Two cytosolic malate dehydrogenase (MDH) isozymes have different spatial expression patterns in certain fishes: ...

journal_title：Journal of molecular evolution

authors： Merrit TJ,Quattro M

更新日期：2003-03-01 00:00:00

abstract：:Pituitary prolactin, like growth hormone (GH) and several other protein hormones, shows an episodic pattern of molecular evolution in which sustained bursts of rapid change contrast with long periods of slow evolution. A period of rapid change occurred in the evolution of prolactin in primates, leading to marked seque...

journal_title：Journal of molecular evolution

authors： Wallis OC,Mac-Kwashie AO,Makri G,Wallis M

更新日期：2005-05-01 00:00:00

abstract：:It has recently been argued that living metazoans diverged over 800 million years ago, based on evidence from 22 nuclear genes for such a deep divergence between vertebrates and arthropods (Gu 1998). Two "internal" calibration points were used. However, only one fossil divergence date (the mammal-bird split) was direc...

journal_title：Journal of molecular evolution

authors： Lee MS

更新日期：1999-09-01 00:00:00

abstract：:Energised by the protonmotive force and with the intervention of inorganic catalysts, at base Life reacts hydrogen from a variety of sources with atmospheric carbon dioxide. It seems inescapable that life emerged to fulfil the same role (i.e., to hydrogenate CO(2)) on the early Earth, thus outcompeting the slow geoche...

journal_title：Journal of molecular evolution

authors： Nitschke W,Russell MJ

更新日期：2009-11-01 00:00:00

abstract：:Many proteins exhibit sequence periodicity, often correlated with a visible structural periodicity. The statistical significance of such periodicity can be assessed by means of a chi-squared-based test, with significance thresholds being calculated from shuffled sequences. Comparison of the complete proteomes of 45 sp...

journal_title：Journal of molecular evolution

authors： Gatherer D,McEwan NR

更新日期：2005-04-01 00:00:00

abstract：:With the aim of elucidating the evolutionary processes of the kringle and protease domains in serine proteases which are involved with the system of blood coagulation and fibrinolysis, we constructed phylogenetic trees for the kringle and protease domains, separately, by use of amino acid sequence data. The phylogenet...

journal_title：Journal of molecular evolution

authors： Ikeo K,Takahashi K,Gojobori T

更新日期：1995-03-01 00:00:00

abstract：:In mammals, chicken-type (c-type) lysozymes are part of the innate immune system, killing bacteria by degrading peptidoglycan in their cell walls. Many of the studies on the evolution of c-type lysozymes have focused on its new digestive function, including the duplicated stomach lysozymes in ruminants. Similarly, in ...

journal_title：Journal of molecular evolution

authors： He C,Wei Y,Zhu Y,Xia Y,Irwin DM,Liu Y

更新日期：2019-12-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) is the first enzyme in the polyamine biosynthetic pathway. We have studied the evolutionary history of the mammalian ODC mRNA, focusing on the rate of accumulation of sequence divergence within specific subregions of the molecule. The phylogenetic relationships among the mRNAs from severa...

journal_title：Journal of molecular evolution

authors： Johannes GJ,Berger FG

更新日期：1993-06-01 00:00:00

abstract：:Orphan genes, lacking detectable homologs in outgroup species, typically represent 10-30% of eukaryotic genomes. Efforts to find the source of these young genes indicate that de novo emergence from non-coding DNA may in part explain their prevalence. Here, we investigate the roots of orphan gene emergence in the Droso...

journal_title：Journal of molecular evolution

authors： Heames B,Schmitz J,Bornberg-Bauer E

更新日期：2020-05-01 00:00:00