Evolution of spliceosomal snRNA genes in metazoan animals.

abstract：:The beta-globin gene cluster of Wistar rat was extensively cloned and the embryonic genes were mapped and sequenced. Four overlapping lambda Dash recombinant clones cover about 31 kb and contain four nonadult beta-globin genes, 5'-epsilon1-gamma1-gamma2-psigamma3-3'. The epsilon1 and gamma2 are active genes, since the...

journal_title：Journal of molecular evolution

authors： Satoh H,Inokuchi N,Nagae Y,Okazaki T

更新日期：1999-07-01 00:00:00

abstract：:We have continued our program aimed at understanding the origin and evolution of the genetic code and the process of protein synthesis by comparing the rates of esterification of 5'-AMP by a series of hydrophobic N-acetylamino acids. The reaction clearly shows differences in reaction rate (AcPhe greater than AcLeu gre...

journal_title：Journal of molecular evolution

authors： Mullins DW Jr,Lacey JC Jr

更新日期：1986-01-01 00:00:00

abstract：:Two families of high-cysteine chorion proteins in Bombyx mori are encoded in 15 tandemly arranged nonidentical gene pairs. It is assumed that this locus arose by duplication with subsequent sequence divergence. We have compared DNA sequences from two such neighboring pairs of genes in an attempt to understand the mann...

journal_title：Journal of molecular evolution

authors： Rodakis GC,Lecanidou R,Eickbush TH

更新日期：1984-01-01 00:00:00

abstract：:Lake Malawi is home to more than 450 species of endemic cichlids, which provide a spectacular example of adaptive radiation. To clarify the phylogenetic relationships among these fish, we examined the presence and absence of SINEs (short interspersed repetitive elements) at orthologous loci. We identified six loci at ...

journal_title：Journal of molecular evolution

authors： Takahashi K,Nishida M,Yuma M,Okada N

更新日期：2001-10-01 00:00:00

abstract：:One of the pupal cuticle protein (PCP) genes has been found within an intron of a Drosophila housekeeping gene (the Gart locus) that encodes three enzymes involved in the purine pathway. This intronic gene has been described as a gene within a gene, and the gene is now called a "nested" gene. Because the intronic PCP ...

journal_title：Journal of molecular evolution

authors： Moriyama EN,Gojobori T

更新日期：1989-05-01 00:00:00

abstract：:The entire mitochondrial DNA control region (mtDNA D-loop) was sequenced in the seven extant species of Alectoris partridges. The D-loop length is very conserved (1155 +/- 2 nucleotides), and substitution rates are lower than for the mitochondrial cytochrome b gene of the same species, on average. Comparative analyses...

journal_title：Journal of molecular evolution

authors： Randi E,Lucchini V

更新日期：1998-10-01 00:00:00

abstract：:Microsatellite DNA sequences have become the dominant source of nuclear genetic markers for most applications. It is important to investigate the basis of variation between alleles and to know if current assumptions about the mechanisms of microsatellite mutation (that is to say, variations involving simple changes in...

journal_title：Journal of molecular evolution

authors： Grimaldi MC,Crouau-Roy B

更新日期：1997-03-01 00:00:00

abstract：:All complete retrovirus sequences in the GenEMBL database were examined with the goal of assessing possible relationships between the nucleotide composition of retroviral genomes, the amino acid composition of retroviral proteins, and evolutionary strategies used by retroviruses. The results demonstrated that the geno...

journal_title：Journal of molecular evolution

authors： Bronson EC,Anderson JN

更新日期：1994-05-01 00:00:00

abstract：:Here we report DNA sequences from mitochondrial cytochrome b gene segments (1,005 base pairs per species) for the extinct woolly mammoth (Mammuthus primigenius) and Steller's sea cow (Hydrodamalis gigas) and the extant Asian elephant (Elephas maximus), the Western Indian manatee (Trichechus manatus), and the hyrax (Pr...

journal_title：Journal of molecular evolution

authors： Ozawa T,Hayashi S,Mikhelson VM

更新日期：1997-04-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small noncoding RNA molecules which are processed into ~20-24 nt molecules that can regulate the gene expression post-transcriptionally. MiRNA gene clusters have been identified in a range of species, where in miRNAs are often processed from polycistronic transcripts. In this study, a computatio...

journal_title：Journal of molecular evolution

authors： de Souza Gomes M,Donoghue MT,Muniyappa M,Pereira RV,Guerra-Sá R,Spillane C

更新日期：2013-06-01 00:00:00

abstract：:LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamar...

journal_title：Journal of molecular evolution

authors： Boissinot S,Roos C,Furano AV

更新日期：2004-01-01 00:00:00

abstract：:In this work detailed statistics on ancestral gene duplication and gene conservation in completely sequenced cellular genomes are presented. Analysis of open reading frame (ORF) products having simultaneous matches in several distinct organisms showed a significant correlation between duplication and conservation. Sys...

journal_title：Journal of molecular evolution

authors： Tekaia F,Dujon B

更新日期：1999-11-01 00:00:00

abstract：:The stability of helical structures formed by polyuridylic acid with nucleosides and nucleotides derived from adenosine is not significantly affected by replacing hydroxyl groups by hydrogen, amino, or azido functions. Stability is affected by the position of the phosphate group. ...

journal_title：Journal of molecular evolution

authors： Gibbs DE,Orgel LE

更新日期：1976-06-23 00:00:00

abstract：:The question of whether natural selection favors genetic stability or genetic variability is a fundamental problem in evolutionary biology. Bioinformatic analyses demonstrate that selection favors genetic stability by avoiding unstable nucleotide sequences in protein encoding DNA. Yet, such unstable sequences are main...

journal_title：Journal of molecular evolution

authors： Falster DS,Nakken S,Bergem-Ohr M,Rødland EA,Breivik J

更新日期：2010-03-01 00:00:00

abstract：:Human endogenous retroviruses (HERVs) are the remnants of ancient germ cell infection by exogenous retroviruses and occupy up to 8% of the human genome. It has been suggested that HERV sequences have contributed to primate evolution by regulating the expression of cellular genes and mediating chromosome rearrangements...

journal_title：Journal of molecular evolution

authors： Macfarlane C,Simmonds P

更新日期：2004-11-01 00:00:00

abstract：:Synonymous codon usage in yeast appears to be influenced by natural selection on gene expression, as well as regional variation in compositional bias. Because of the large number of potential targets of selection (i.e., most of the codons in the genome) and presumed small selection coefficients, codon usage is an exce...

journal_title：Journal of molecular evolution

authors： Kliman RM,Irving N,Santiago M

更新日期：2003-07-01 00:00:00

abstract：:The circadian clock regulates a multitude of plant developmental and metabolic processes. In crop species, it contributes significantly to plant performance and productivity and to the adaptation and geographical range over which crops can be grown. To understand the clock in barley and how it relates to the component...

journal_title：Journal of molecular evolution

authors： Calixto CP,Waugh R,Brown JW

更新日期：2015-02-01 00:00:00

abstract：:Bacterial family C DNA polymerases (DNA pol IIIs), the major chromosomal replicative enzymes, have been provisionally classified based on primary sequences and domain structures into three classes: class I (Escherichia coli DNA pol C-type), class II (Bacillus subtilis DNA pol C-type), and class III (cyanobacterial DNA...

journal_title：Journal of molecular evolution

authors： Huang YP,Ito J

更新日期：1999-06-01 00:00:00

abstract：:Life is based on biopolymers that have the ability to replicate themselves. Here we consider how a self-replicating RNA system may have originated. We consider a reaction system in which polymerization is possible by the addition of an activated monomer to the end of a chain. We suppose that a small fraction of polyme...

journal_title：Journal of molecular evolution

authors： Wu M,Higgs PG

更新日期：2009-11-01 00:00:00

abstract：:The observed and expected frequencies of occurrence of microsatellites in the yeast Saccharomyces cerevisiae were investigated. In all cases, the observed frequencies exceeded the expected ones. In contrast to predictions by Messier et al. (1996), there is no critical number of repeats beyond which the observed freque...

journal_title：Journal of molecular evolution

authors： Pupko T,Graur D

更新日期：1999-03-01 00:00:00

abstract：:A fundamental paradox motivates the study of plant mitochondrial genomics: the mutation rate is very low (lower than in the nucleus) but the rearrangement rate is high. A landmark paper published in Journal of Molecular Evolution in 1988 established these facts and revealed the paradox. Jeffrey Palmer and Laura Herbon...

journal_title：Journal of molecular evolution

authors： Christensen AC

更新日期：2021-01-24 00:00:00

abstract：:We analyzed precursor messenger RNAs (pre-mRNAs) of 12 eukaryotic species. In each species, three groups of highly expressed genes, ribosomal proteins, heat shock proteins, and amino-acyl tRNA synthetases, were compared with a control group (randomly selected genes). The purine-pyrimidine (R-Y) composition of pre-mRNA...

journal_title：Journal of molecular evolution

authors： Paz A,Mester D,Nevo E,Korol A

更新日期：2007-02-01 00:00:00

abstract：:An exhaustive computer-assisted analysis of the Moloney murine leukemia virus nucleotide sequence shows numerous deviations in the oligomeric distribution, suggesting three overlapping levels of a stepwise duplicative evolution. (1) The sequence fits the universal rule of TG/CT excess which has been proposed as the co...

journal_title：Journal of molecular evolution

authors： Laprevotte I

更新日期：1992-11-01 00:00:00

abstract：:The C-terminal domain of methionyl-tRNA synthetase (MetRS-C) from Nanoarchaeum equitans is homologous to a tRNA-binding protein consisting of 111 amino acids (Trbp111) from Aquifex aeolicus. The crystal structure of MetRS-C showed that it existed as a homodimer, and that each monomer possessed an oligonucleotide/oligo...

journal_title：Journal of molecular evolution

authors： Suzuki H,Kaneko A,Yamamoto T,Nambo M,Hirasawa I,Umehara T,Yoshida H,Park SY,Tamura K

更新日期：2017-06-01 00:00:00

abstract：:We describe the structure of a gene expressed in the salivary gland cells of the dipteran Chironomus tentans and show that it encodes 1 of the approximately 15 secretory proteins exported by the gland cells. This sp115,140 gene consists of approximately 65 copies of a 42-bp sequence in a central uninterrupted core blo...

journal_title：Journal of molecular evolution

authors： Galli J,Lendahl U,Paulsson G,Ericsson C,Bergman T,Carlquist M,Wieslander L

更新日期：1990-07-01 00:00:00

abstract：:We have studied the metal-ion catalysis of a number of reactions of the isomers of ImpGpG on a poly(C) template. In the absence of a catalytic metal ion, oligomers at least up to (pG)20 are obtained from the ImpGpG isomers in a 1-methylimidazole buffer. The Pb2+ ion improves the yield of longer oligomers and changes s...

journal_title：Journal of molecular evolution

authors： Lohrmann R,Bridson PK,Orgel LE

更新日期：1981-01-01 00:00:00

abstract：:Cot and chemical analysis show that the haploid genome size of Thermobia domestica is 3-4x10(9) nucleotide pairs. Of this DNA 33% is single copy sequences and 67% is repetitive sequences. The repetitive sequences are predominantly 300 nucleotides in length and are interspersed among the single copy sequences in a shor...

journal_title：Journal of molecular evolution

authors： French CK,Manning JE

更新日期：1980-08-01 00:00:00

abstract：:In bacteria, synonymous codon usage can be considerably affected by base composition at neighboring sites. Such context-dependent biases may be caused by either selection against specific nucleotide motifs or context-dependent mutation biases. Here we consider the evolutionary conservation of context-dependent codon b...

journal_title：Journal of molecular evolution

authors： McVean GA,Hurst GD

更新日期：2000-03-01 00:00:00

abstract：:HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1. Since then, numerous sequences of HMG-box-containing HMG proteins and other DNA-binding proteins from several species have become avai...

journal_title：Journal of molecular evolution

authors： Griess EA,Rensing SA,Grasser KD,Maier UG,Feix G

更新日期：1993-08-01 00:00:00

abstract：:It is generally considered that if an RNA World ever existed that it would be driven by an RNA capable of RNA replication. Whether such a catalytic RNA could emerge in an RNA World or not, there would need to be prior routes to increasing complexity in order to produce it. It is hypothesized here that increasing seque...

journal_title：Journal of molecular evolution

authors： Tirumalai MR,Tran Q,Paci M,Chavan D,Marathe A,Fox GE

更新日期：2018-06-01 00:00:00