MgtC as a horizontally-acquired virulence factor of intracellular bacterial pathogens: evidence from molecular phylogeny and comparative genomics.

abstract：:Transbilayer diffusion of Mn2+ ions occurred in liposomes formed from dipalmitoyl-phosphatidylcholine or egg-yolk phosphatidylcholine and egg-yolk phosphatidate (molar ratio 2:1) containing DNA and DNase I within their aqueous compartments. Cation diffusion was demonstrated by the hydrolytic activity of DNase I, activ...

journal_title：Journal of molecular evolution

authors： Baeza I,Ibáñez M,Santiago JC,Argüello C,Wong C,Oró J

更新日期：1990-12-01 00:00:00

abstract：:Universal scale of the sequence conservation has been recently introduced based on omnipresence of the protein sequence motifs across species. A large spectrum of short sequences, up to eight residues has been found to reside in all or almost all prokaryotic organisms. By this discovery a principally novel quantitativ...

journal_title：Journal of molecular evolution

authors： Sobolevsky Y,Trifonov EN

更新日期：2006-11-01 00:00:00

abstract：:The transposable element mariner occurs widely in the melanogaster species group of Drosophila. However, in drosophilids outside of the melanogaster species group, sequences showing strong DNA hybridization with mariner are found only in the genus Zaprionus. The mariner sequence obtained from Zaprionus tuberculatus is...

journal_title：Journal of molecular evolution

authors： Maruyama K,Hartl DL

更新日期：1991-12-01 00:00:00

abstract：:Processes exhibiting diversity and selection would have been necessary to promote chemical evolution on early Earth. In this work, a model process was developed using non-kinetic selection to synthesize and isolate small molecule imidazolium catalysts. These catalysts were purified by affinity chromatography and recyc...

journal_title：Journal of molecular evolution

authors： Clairmont RM,Bommarius AS,Weber AL

更新日期：2015-08-01 00:00:00

abstract：:Genes encoding the olfactory receptors of the "OR37" subfamily of the mouse are characterized by special features including a clustered expression pattern, assembly in two distinct gene clusters, and highly conserved putative promoter motifs. Mining the rat and dog databases revealed that these two species possess hig...

journal_title：Journal of molecular evolution

authors： Hoppe R,Lambert TD,Samollow PB,Breer H,Strotmann J

更新日期：2006-04-01 00:00:00

abstract：:Adenosine 5'-phosphoramidates form when solutions containing adenosine 5'-polyphosphates pnA (n greater than or equal to 3) or P1, P2-diadenosine 5'-diphosphate and amines are allowed to dry out. Mg ions catalyze these reactions. We have studied systems containing ammonia, imidazole, glycine, ethylenediamine and hista...

journal_title：Journal of molecular evolution

authors： Lohrmann R

更新日期：1977-11-25 00:00:00

abstract：:The codons in four mammalian messenger RNAs (rabbit beta hemoglobin, rat pre-proinsulin, rat pre-growth hormone and human chorionic somatomammotropin) show a predominance of C and G in third nucleotide positions. The C:U ratio is about 2 to 1, and the G:A ratio is about 4 to 1. The possibility is discussed that this d...

journal_title：Journal of molecular evolution

authors： Jukes TH

更新日期：1978-06-20 00:00:00

abstract：:Selection pressures on proteins are usually measured by comparing homologous nucleotide sequences (Zuckerkandl and Pauling 1965). Recently we introduced a novel method, termed volatility, to estimate selection pressures on proteins on the basis of their synonymous codon usage (Plotkin and Dushoff 2003; Plotkin et al. ...

journal_title：Journal of molecular evolution

authors： Plotkin JB,Dushoff J,Desai MM,Fraser HB

更新日期：2006-11-01 00:00:00

abstract：:Males of three inbred lines of Drosophila melanogaster were heat-shocked 90 min at 37 degrees C. The progenies from treated and untreated males mated with untreated females of the same line were checked for their chromosomal insertion patterns of various mobile elements by either in situ hybridization or Southern blot...

journal_title：Journal of molecular evolution

authors： Arnault C,Biémont C

更新日期：1989-05-01 00:00:00

abstract：:The relaxin (RLN) and insulin-like (INSL) gene family is a group of genes involved in a variety of physiological roles that includes bone formation, testicular descent, trophoblast development, and cell differentiation. This family appears to have expanded in vertebrates relative to non-vertebrate chordates, but the r...

journal_title：Journal of molecular evolution

authors： Hoffmann FG,Opazo JC

更新日期：2011-01-01 00:00:00

abstract：:TT virus (TTV) has a remarkable genetic heterogeneity. To study TTV evolution, phylogenetic analyses were performed on 739 DNA sequences mapping in the N22 region of ORF1. Analysis of neighbor-joining consensus trees shows significant differences between DNA and protein phylogeny. Median joining networks phylogenetic ...

journal_title：Journal of molecular evolution

authors： Manni F,Rotola A,Caselli E,Bertorelle G,Di Luca D

更新日期：2002-11-01 00:00:00

abstract：:Cytochrome proteins perform a broad spectrum of biological functions ranging from oxidative metabolism to electron transport and are thus essential to all organisms. The b-type cytochrome proteins bind heme noncovalently, are expressed in many different forms and are localized to various cellular compartments. We repo...

journal_title：Journal of molecular evolution

authors： Kula ME,Allay ER,Rozek CE

更新日期：1995-10-01 00:00:00

abstract：:Hypothetical Products from Noncoding Frames (i.e., HyPNoFs) are hypothetical, not-coded proteins, translated from alternate reading frames (i.e., coding + 1 and coding + 2) of cDNAs. HyPNoFs of CD4, PKC, oncostatin, bcl-2 proto-oncogene, tumor suppressor p53, cystic fibrosis transmembrane regulator (CFTR), and tumor n...

journal_title：Journal of molecular evolution

authors： Facchiano A

更新日期：1995-06-01 00:00:00

abstract：:It is generally considered that if an RNA World ever existed that it would be driven by an RNA capable of RNA replication. Whether such a catalytic RNA could emerge in an RNA World or not, there would need to be prior routes to increasing complexity in order to produce it. It is hypothesized here that increasing seque...

journal_title：Journal of molecular evolution

authors： Tirumalai MR,Tran Q,Paci M,Chavan D,Marathe A,Fox GE

更新日期：2018-06-01 00:00:00

abstract：:The circadian clock regulates a multitude of plant developmental and metabolic processes. In crop species, it contributes significantly to plant performance and productivity and to the adaptation and geographical range over which crops can be grown. To understand the clock in barley and how it relates to the component...

journal_title：Journal of molecular evolution

authors： Calixto CP,Waugh R,Brown JW

更新日期：2015-02-01 00:00:00

abstract：:Human endogenous retroviruses (HERVs) are the remnants of ancient germ cell infection by exogenous retroviruses and occupy up to 8% of the human genome. It has been suggested that HERV sequences have contributed to primate evolution by regulating the expression of cellular genes and mediating chromosome rearrangements...

journal_title：Journal of molecular evolution

authors： Macfarlane C,Simmonds P

更新日期：2004-11-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small noncoding RNA molecules which are processed into ~20-24 nt molecules that can regulate the gene expression post-transcriptionally. MiRNA gene clusters have been identified in a range of species, where in miRNAs are often processed from polycistronic transcripts. In this study, a computatio...

journal_title：Journal of molecular evolution

authors： de Souza Gomes M,Donoghue MT,Muniyappa M,Pereira RV,Guerra-Sá R,Spillane C

更新日期：2013-06-01 00:00:00

abstract：:Heat induces a number of premutational lesions (for example, the deamination of cytosine to uracil) in DNA and RNA. These kinds of errors occur in resting as well as replicating polynucleotides. However, an increase in temperature also raises the probability of copying error occurring in nucleic acids because of incre...

journal_title：Journal of molecular evolution

authors： Reanney DC,Pressing J

更新日期：1984-01-01 00:00:00

abstract：:A long-standing hypothesis posits that morphological changes may be more likely to result from changes in regulation of gene expression than from changes in the protein coding sequences of genes. We have compared the expression pattern of the twisted gastrulation (tsg) gene among five Drosophila species: D. melanogast...

journal_title：Journal of molecular evolution

authors： Mason ED,Marsh JL

更新日期：1998-02-01 00:00:00

abstract：:This study was designed to characterize further the nontranscribed intergenic spacers (NTSs) of the 5S rRNA genes of fish and evaluate this marker as a tool for comparative studies. Two members of the closely related North American Great Lakes cisco species complex (Coregonus artedi and C. zenithicus) were chosen for ...

journal_title：Journal of molecular evolution

authors： Sajdak SL,Reed KM,Phillips RB

更新日期：1998-06-01 00:00:00

abstract：:Sequence data from regions of five vertebrate vitellogenin genes were used to examine the frequency, distribution, and mutability of the dinucleotide CpG, the preferred modification site for eukaryotic DNA methyltransferases. The observed level of the CpG dinucleotide in all five genes was markedly lower than that exp...

journal_title：Journal of molecular evolution

authors： Cooper DN,Gerber-Huber S,Nardelli D,Schubiger JL,Wahli W

更新日期：1987-01-01 00:00:00

abstract：:A model of nucleotide substitution that allows the transition/transversion rate bias to vary across sites was constructed. We examined the fit of this model using likelihood-ratio tests by analyzing 13 protein coding genes and 1 pseudogene. Likelihood-ratio testing indicated that a model that allows variation in the t...

journal_title：Journal of molecular evolution

authors： Huelsenbeck JP,Nielsen R

更新日期：1999-01-01 00:00:00

abstract：:The core histone genes of Saccharomyces cerevisiae are arranged as duplicate nonallelic sets of specifically paired genes. The identity of structural organization between the duplicated gene pairs would have its simplest evolutionary origin in the duplication of a complete locus in a single event. In such a case, the ...

journal_title：Journal of molecular evolution

authors： Smith MM

更新日期：1987-01-01 00:00:00

abstract：:We have implemented a routine procedure for screening protein sequences for evidence of intragenic duplications. We tested 163 protein sequences representing 116 superfamilies of unrelated proteins. Twenty superfamilies contain proteins with internal gene duplications. The intragenic duplications detected can be divid...

journal_title：Journal of molecular evolution

authors： Barker WC,Ketcham LK,Dayhoff MO

更新日期：1978-02-21 00:00:00

abstract：:DEAD-box proteins are found in all domains of life and participate in almost all cellular processes that involve RNA. The presence of DEAD and Helicase_C conserved domains distinguish these proteins. DEAD-box proteins exhibit RNA-dependent ATPase activity in vitro, and several also show RNA helicase activity. In this ...

journal_title：Journal of molecular evolution

authors： López-Ramírez V,Alcaraz LD,Moreno-Hagelsieb G,Olmedo-Álvarez G

更新日期：2011-04-01 00:00:00

abstract：:The beta-globin gene cluster of Wistar rat was extensively cloned and the embryonic genes were mapped and sequenced. Four overlapping lambda Dash recombinant clones cover about 31 kb and contain four nonadult beta-globin genes, 5'-epsilon1-gamma1-gamma2-psigamma3-3'. The epsilon1 and gamma2 are active genes, since the...

journal_title：Journal of molecular evolution

authors： Satoh H,Inokuchi N,Nagae Y,Okazaki T

更新日期：1999-07-01 00:00:00

abstract：:Members of the serpin (serine protease inhibitor) superfamily of genes are well represented in both human and murine genomes. In many cases it is possible to identify a definite ortholog on the basis of sequence similarity and by examining the surrounding genes at syntenic loci. We have recently examined the murine se...

journal_title：Journal of molecular evolution

authors： Horvath AJ,Forsyth SL,Coughlin PB

更新日期：2004-10-01 00:00:00

abstract：:The codon assignment of the quasi-universal genetic code can be assumed to have resulted from the evolutionary pressures that prevailed when the code was still evolving. Here, we review studies of the structure of the genetic code based on optimization models. We also review studies that, from the structure of the cod...

journal_title：Journal of molecular evolution

authors： Jestin JL,Kempf A

更新日期：2009-11-01 00:00:00

abstract：:In the present study we focus on the nucleotide and the inferred amino acid variation occurring in humans and other primate species for mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase, a gene recently supposed to contribute to cognitive performance in humans. We determined 2527 bp of coding, introni...

journal_title：Journal of molecular evolution

authors： Blasi P,Palmerio F,Aiello A,Rocchi M,Malaspina P,Novelletto A

更新日期：2006-07-01 00:00:00

abstract：:Glaucocystophyte algae (sensu Kies, Berl. Deutsch. Bot. Ges. 92, 1979) contain plastids (cyanelles) that retain the peptidoglycan wall of the putative cyano-bacterial endosymbiont; this and other ultrastructural characters (e.g., unstacked thylakoids, phycobilisomes) have suggested that cyanelles are "primitive" plast...

journal_title：Journal of molecular evolution

authors： Helmchen TA,Bhattacharya D,Melkonian M

更新日期：1995-08-01 00:00:00