Investigating hypothetical products from noncoding frames (HyPNoFs).

abstract：:The accuracies and efficiencies of three different methods of making phylogenetic trees from gene frequency data were examined by using computer simulation. The methods examined are UPGMA, Farris' (1972) method, and Tateno et al.'s (1982) modified Farris method. In the computer simulation eight species (or populations...

journal_title：Journal of molecular evolution

authors： Nei M,Tajima F,Tateno Y

更新日期：1983-01-01 00:00:00

abstract：:Recent experience with molecular phylogeny has shown that all molecular markers have strengths and weaknesses. Nonetheless, despite several notable discrepancies with phylogenies obtained from protein data, the merits of the small subunit ribosomal RNA (SSU rRNA) as a molecular phylogenetic marker remain indisputable....

journal_title：Journal of molecular evolution

authors： Van de Peer Y,Baldauf SL,Doolittle WF,Meyer A

更新日期：2000-12-01 00:00:00

abstract：:It is known that globin genes contain three exons with the middle exon coding for a four-helical supersecondary structure responsible for heme binding. Since this portion of the globin peptide chain can be structurally superimposed onto the cytochrome c and cytochrome b5 chains (Argos and Rossmann 1979), it can be inf...

journal_title：Journal of molecular evolution

authors： Argos P,Rossmann MG

更新日期：1980-12-01 00:00:00

abstract：:This study investigated the evolution of a transition metal ion-binding cluster ([H--X--X--X--H](n); Tx) in the alternatively spliced NH(2)-terminal variable region of avian pectoral muscle troponin T (TnT). Encoded by avian fast skeletal muscle TnT-specific P exons, Tx-like structures were expressed in the breast mus...

journal_title：Journal of molecular evolution

authors： Jin JP,Samanez RA

更新日期：2001-02-01 00:00:00

abstract：:The circadian clock regulates a multitude of plant developmental and metabolic processes. In crop species, it contributes significantly to plant performance and productivity and to the adaptation and geographical range over which crops can be grown. To understand the clock in barley and how it relates to the component...

journal_title：Journal of molecular evolution

authors： Calixto CP,Waugh R,Brown JW

更新日期：2015-02-01 00:00:00

abstract：:Antibody binding site are formed by six hypervariable regions or complementarity determining regions (CDRs). The CDRs, three from the heavy chain and three from the light chain, are known as hypervariable segments and provide a surface complementary to that of the epitope. In recent work it was found that the amino ac...

journal_title：Journal of molecular evolution

authors： Vargas-Madrazo E,Lara-Ochoa F,Jiménez-Montaño M

更新日期：1994-01-01 00:00:00

abstract：:Here we report DNA sequences from mitochondrial cytochrome b gene segments (1,005 base pairs per species) for the extinct woolly mammoth (Mammuthus primigenius) and Steller's sea cow (Hydrodamalis gigas) and the extant Asian elephant (Elephas maximus), the Western Indian manatee (Trichechus manatus), and the hyrax (Pr...

journal_title：Journal of molecular evolution

authors： Ozawa T,Hayashi S,Mikhelson VM

更新日期：1997-04-01 00:00:00

abstract：:The transposable element mariner occurs widely in the melanogaster species group of Drosophila. However, in drosophilids outside of the melanogaster species group, sequences showing strong DNA hybridization with mariner are found only in the genus Zaprionus. The mariner sequence obtained from Zaprionus tuberculatus is...

journal_title：Journal of molecular evolution

authors： Maruyama K,Hartl DL

更新日期：1991-12-01 00:00:00

abstract：:The 5S ribosomal RNA sequences have been determined for the rhodoplast of the red alga Porphyra umbilicalis and the chloroplast of the conifer Juniperus media. The 5S RNA sequence of the Vicia faba chloroplast is corrected with respect to a previous report. A survey of the known sequences and secondary structures of 5...

journal_title：Journal of molecular evolution

authors： Van den Eynde H,De Baere R,De Roeck E,Van de Peer Y,Vandenberghe A,Willekens P,De Wachter R

更新日期：1988-01-01 00:00:00

abstract：:Quantitative immunological comparisons of three avian proteins, transferrin, ovalbumin, and penalbumin, indicate that penguins are phylogenetically most closely related to loons, albatrosses, herons, and grebes. These data support the theory that the ancestors of penguins were flying oceanic birds and that flightlessn...

journal_title：Journal of molecular evolution

authors： Ho CY,Prager EM,Wilson AC,Osuga DT,Feeney RE

更新日期：1976-10-27 00:00:00

abstract：:Eight human short tandem repeat polymorphisms (STRs) also known as microsatellites-DYS19, DYS388, DYS390, DYS391, DYS392, DYS393, DYS389I, and DYS389II, mapping in the Y chromosome-were analyzed in two Iberian samples (Basques and Catalans). Allele frequency distributions showed significant differences only for DYS392...

journal_title：Journal of molecular evolution

authors： Pérez-Lezaun A,Calafell F,Seielstad M,Mateu E,Comas D,Bosch E,Bertranpetit J

更新日期：1997-09-01 00:00:00

abstract：:Horizontal gene transfer (HGT) has a major impact on the evolution of prokaryotic genomes, as it allows genes evolved in different contexts to be combined in a single genome, greatly enhancing the ways evolving organisms can explore the gene content space and adapt to the environment. A systematic analysis of HGT in a...

journal_title：Journal of molecular evolution

authors： Paquola ACM,Asif H,Pereira CAB,Feltes BC,Bonatto D,Lima WC,Menck CFM

更新日期：2018-04-01 00:00:00

abstract：:We have used three reference sequences representative of bacterial drug resistance pumps and sugar transport proteins to collect the 91 most closely related sequences from a composite, nonredundant protein sequence database. Having eliminated certain very close relatives, the remainder were subjected to analysis and a...

journal_title：Journal of molecular evolution

authors： Parish JH,Bentley J

更新日期：1996-02-01 00:00:00

abstract：:Autosomal chorion genes s18, s15, and s19 are shown to diverge at extremely rapid rates in closely related taxa of Hawaiian Drosophila. Their nucleotide divergence rates are at least as fast as those of intergenic regions that are known to evolve more extensively between distantly related species. Their amino acid div...

journal_title：Journal of molecular evolution

authors： Martínez-Cruzado JC

更新日期：1990-11-01 00:00:00

abstract：:Since their discovery in Metazoa, the three nuclear RNA polymerases (RNAPs) have been found in fungi, plants, and diverse protists. In all eukaryotes studied to date, RNAPs I, II, and III collectively transcribe all major RNAs made in the nucleus. We have found genes for the largest subunit (RPD1/RPE1) of a new DNA-de...

journal_title：Journal of molecular evolution

authors： Luo J,Hall BD

更新日期：2007-01-01 00:00:00

abstract：:The core histone genes of Saccharomyces cerevisiae are arranged as duplicate nonallelic sets of specifically paired genes. The identity of structural organization between the duplicated gene pairs would have its simplest evolutionary origin in the duplication of a complete locus in a single event. In such a case, the ...

journal_title：Journal of molecular evolution

authors： Smith MM

更新日期：1987-01-01 00:00:00

abstract：:Rooted phylogenetic trees for a total of 34 genes encoding the stimulatory (s alpha), inhibitory (i alpha), transducin (t alpha), Gx (x alpha), Gz (z alpha), G11 (alpha 11), G12 (alpha 12), G13 (alpha 13), G16 (alpha 16), Gq (q alpha), and other (o alpha) G protein alpha subunits have been constructed. The analysis sh...

journal_title：Journal of molecular evolution

authors： Yokoyama S,Starmer WT

更新日期：1992-09-01 00:00:00

abstract：:Scorpion venom toxins were systematically classified according to amino acid composition, insertion/deletion events and sequence. The significance of each comparison method and its outcome is discussed in relation to known immunological and structural properties. A general classification of the toxins is proposed that...

journal_title：Journal of molecular evolution

authors： Dufton MJ,Rochat H

更新日期：1984-01-01 00:00:00

abstract：:Protamine P1 genes have been sequenced following PCR amplification from 11 mammals representing five major mammalian orders: Rodentia (rat and guinea pig), Carnivora (cat and bear), Proboscidea (elephant), Perissodactyla (horse), and Artiodactyla (camel, deer, elk, moose, and gazelle). The predicted amino acid sequenc...

journal_title：Journal of molecular evolution

authors： Queralt R,Adroer R,Oliva R,Winkfein RJ,Retief JD,Dixon GH

更新日期：1995-06-01 00:00:00

abstract：:Previous observations have indicated that Drosophila DNA contains a component that evolves so rapidly that it fails to hybridize between the DNAs of sibling species. To establish the reality of this component and study its properties, the fraction (about 20%) of Drosophila simulans (Dsim) DNA that fails to hybridize t...

journal_title：Journal of molecular evolution

authors： Werman SD,Davidson EH,Britten RJ

更新日期：1990-03-01 00:00:00

abstract：:This study dealt with the ability of non-denaturing gel electrophoresis to separate iso-1-cytochrome c with single amino acid replacements isolated from revertants of various cyc1 nonsense mutants of the yeast Saccharomyces cerevisiae. A total of 28 different iso-1-cytochromes c with single amino acid substitutions of...

journal_title：Journal of molecular evolution

authors： McLellan T,Sherman F

更新日期：1991-10-01 00:00:00

abstract：:The usage of synonymous codons and the frequencies of amino acids were investigated in the complete genome of the bacterium Thermotoga maritima using a multivariate statistical approach. The GC3 content of each gene was the most prominent source of variation of codon usage. Surprisingly the usage of UGU and UGC (synon...

journal_title：Journal of molecular evolution

authors： Zavala A,Naya H,Romero H,Musto H

更新日期：2002-05-01 00:00:00

abstract：:The mutation and selection of regulatory DNA sequences are presented as an ideal model system of molecular evolution where genotype, phenotype, and fitness can be explicitly and independently characterized. In this theoretical study, we construct an explicit model for the evolution of regulatory sequences, making use ...

journal_title：Journal of molecular evolution

authors： Gerland U,Hwa T

更新日期：2002-10-01 00:00:00

abstract：:To get a better understanding of the effect of interelement selection on the variation of long terminal repeat retrotransposon families, we have investigated the evolutionary history of blood in the Drosophila melanogaster species complex. We carried out a PCR approach to amplify the 5' untranslated region from blood ...

journal_title：Journal of molecular evolution

authors： Costas J,Valadé E,Naveira H

更新日期：2001-04-01 00:00:00

abstract：:Covarion processes allow changes in evolutionary rates at sites along the branches of a phylogenetic tree. Covarion-like evolution is increasingly recognized as an important mode of protein evolution. Several recent reports suggest that maximum likelihood estimation employing covarion models may support different opti...

journal_title：Journal of molecular evolution

authors： Wang HC,Susko E,Spencer M,Roger AJ

更新日期：2008-01-01 00:00:00

abstract：:Gene duplication by retrotransposition duplicates only the coding and untranslated regions of a gene and, thus, biases retroduplicated genes toward having different expression patterns from their parental genes. As such, genes duplicated by retrotransposition are more likely to develop novel expression domains. To exp...

journal_title：Journal of molecular evolution

authors： Penney J,Bossé J,Clark DV

更新日期：2008-05-01 00:00:00

abstract：:51 polypeptides of known 3-dimensional structures have been submitted to a search for internal similarities. It is shown that the frequency of proteins displaying significant amounts of internal similarities is higher than predicted by chance. A non-negligible part of those similarities probably occurs in connection w...

journal_title：Journal of molecular evolution

authors： Wuilmart C,Delhaise P

更新日期：1983-01-01 00:00:00

abstract：:The neutral theory of molecular evolution states that most mutations are deleterious or neutral. It results that the evolutionary rate of a given position in an alignment is a function of the level of constraint acting on this position. Inferring evolutionary rates from a set of aligned sequences is hence a powerful m...

journal_title：Journal of molecular evolution

authors： Dutheil J

更新日期：2008-09-01 00:00:00

abstract：:The semen of many primate species coagulates into a mating plug believed to prevent the sperm of subsequent mating events from accessing the ova. The texture of the coagulum varies among species: from a semisoft mass in humans to a firm plug in chimpanzees. In humans, a component of the coagulum, semenogelin I, also i...

journal_title：Journal of molecular evolution

authors： Kingan SB,Tatar M,Rand DM

更新日期：2003-08-01 00:00:00

abstract：:The Pten gene was initially identified in humans as a tumor suppressor. It has since been shown to play important roles in the control of cell size, cell motility, apoptosis, and organ size, and it has also been implicated in aging. Pten is highly conserved among organisms as diverse as nematodes, insects, and vertebr...

journal_title：Journal of molecular evolution

authors： Baudry E,Desmadril M,Werren JH

更新日期：2006-06-01 00:00:00