Abstract：
:The SOS response can be induced indirectly in Escherichia coli by infection with UV irradiated bacteriophage P1, lambda or M13. Induction, monitored quantitatively by means of a sfiA::lac operon fusion, was stronger with the plasmid phage P1 than with lambda, but the kinetics were similar, showing that plasmid and non-plasmid phages are not fundamentally different in their ability to produce indirect induction. In the absence of lambda DNA replication the level of induction was strongly reduced, indicating that the attempt to replicate damaged DNA results in induction of the SOS response. The slight residual induction observed in the absence of DNA replication suggests the existence of a second pathway leading from DNA lesions to induction of the SOS response.
journal_name
Biochimiejournal_title
Biochimieauthors
D'Ari R,Huisman Odoi
10.1016/s0300-9084(82)80100-4subject
Has Abstractpub_date
1982-08-01 00:00:00pages
623-7issue
8-9eissn
0300-9084issn
1638-6183pii
S0300-9084(82)80100-4journal_volume
64pub_type
杂志文章相关文献
BIOCHIMIE文献大全abstract：:The vasoactive hormone bradykinin, its N-and C-terminal fragments and some structural analogues were studied by Circular Dichroism. Conformational features of the peptide can be detected by comparative analysis of the various CD spectra recorded as a function of aqueous pH, solvent and temperature. It is shown that th...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(79)80316-8
更新日期：1979-01-01 00:00:00
abstract：:The measurement and potential technological significance of in vivo missense errors are briefly reviewed. A recently developed approach is described in which reporter enzyme activity is generated by mistranslation of a gene coding for an inactive mutant form of the enzyme. Initial results obtained using the alpha subu...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/0300-9084(91)90192-4
更新日期：1991-12-01 00:00:00
abstract：:Stereospecific hydrogenations according to the general scheme [formula: see text] are of interest from a preparative and mechanistic point of view. Proteus mirabilis is suitable for the hydrogenation of a-keto-acids to R-hydroxy-acids, and a Clostridium strain for the reduction of enoates. Both have been immobilized i...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(80)80162-3
更新日期：1980-01-01 00:00:00
abstract：:In the bacterium Escherichia coli, H-NS-(H1, H1a) is a heat-stable protein with a molecular mass of 15.5 kDa involved in nucleoid organisation and gene regulation linked to certain signal transduction pathways. We have shown that, following addition of preparations of everted inner membrane vesicles, heat-stable cleav...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(97)80025-9
更新日期：1997-06-01 00:00:00
abstract：:A thrombin-like enzyme, named BjussuSP-I, isolated from Bothrops jararacussu snake venom, is an acidic single-chain glycoprotein with M(r)=61,000, pI approximately 3.8 and 6% sugar. BjussuSP-I shows high proteolytic activity upon synthetic substrates, such as S-2238 and S-2288. It also shows procoagulant and kallikrei...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2007.10.005
更新日期：2008-03-01 00:00:00
abstract：:Laccases, blue copper-containing oxidases, ≿ an play an important role in a variety of natural processes. The majority of fungal laccases are encoded by multigene families that express closely related proteins with distinct functions. Currently, only the properties of major gene products of the fungal laccase families...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2015.07.015
更新日期：2015-09-01 00:00:00
abstract：:We previously reported that the rRNA methyltransferases RsmI and RsmH, which are responsible for cytidine dimethylation at position 1402 of 16S rRNA in the decoding center of the ribosome, contribute to Staphylococcus aureus virulence. Here we evaluated other 16S rRNA methyltransferases, including KsgA (RsmA), RsmB/F,...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2015.10.027
更新日期：2015-12-01 00:00:00
abstract：:After treatment of L929 cells, a murine fibrosarcoma line, with tumor necrosis factor (TNF), a nuclear kappa B-like transcription factor is rapidly induced as identified by gel shift mobility assays using the kappa B-responsive sequence of the immunoglobulin or interleukin-6 (IL-6) genes as a DNA probe. When induction...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(93)90153-j
更新日期：1993-01-01 00:00:00
abstract：:Alteration of the epigenome is associated with a wide range of human diseases. Therefore, deciphering the pathways that regulate the epigenetic modulation of gene expression is a major milestone for the understanding of diverse biological mechanisms and subsequently human pathologies. Although often evoked, little is ...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2007.07.022
更新日期：2008-01-01 00:00:00
abstract：:The systems involving folate and cobalamin have several features in common: 1) their dietary forms require luminal digestion for absorption; 2) intestinal bacteria in the upper intestine synthesize and utilize both vitamins, creating possible competition for the nutrients; 3) there is one major intestinal brush border...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2015.11.006
更新日期：2016-07-01 00:00:00
abstract：:Explants from 7, 8, 9, 11, 13-day chick embryonic skin incorporating (3H) Uridine for different periods 1 hr, 3 or 4 hr and a chase with actinomycin) are studied with respect to free (F) or membrane bound (B) cytoplasmic polysomes and to RNA extracted from them. Polysome specific activity decreases at older stages but...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(76)80226-x
更新日期：1976-01-01 00:00:00
abstract：:Nitroxyl (HNO) is a molecule of significant interest due to its unique pharmacological properties, particularly within the cardiovascular system. A large portion of HNO biological effects can be attributed to its reactivity with protein thiols, where it can generate disulfide bonds. Evidence from studies in erythrocyt...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2011.12.005
更新日期：2012-03-01 00:00:00
abstract：:The issue of whether histone H1 possesses specificity of binding to certain nucleotide sequences in DNA is of fundamental importance to the suggested role of the linker histone in the regulation of gene transcription. The purpose of the present study was to reinvestigate the specificity of binding of histone H1 to the...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(93)90116-a
更新日期：1993-01-01 00:00:00
abstract：:Trypsin and pronase treatment of purified human neutral bronchial mucins released small fragments from the C-terminal end of these molecules and resulted in slight increases in their sedimentation coefficient presumably reflecting conformational changes. The antigenic determinant of neutral bronchial mucins which appe...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(76)80444-0
更新日期：1976-01-01 00:00:00
abstract：:Cell walls of flocculent strains (0006) and non flocculent strains (0019) of Saccharomyces uvarum (Carlsbergensis), grown in different media and taken in both growth and stationary phases, were treated with water and with 2 per cent (W/V) potassium hydroxide. This treatment yielded four fractions (FI, FII, FIII and FR...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(81)80055-7
更新日期：1981-07-01 00:00:00
abstract：:Cryptogein, a 98 amino acid protein secreted by the fungus Phytophthora cryptogea, induces a hypersensitive response and systemic acquired resistance in tobacco plants (Nicotiana tabacum var Xanthi). The mode of action of cryptogein has been studied using tobacco cell suspensions. The recognition of this elicitor by a...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/s0300-9084(99)80123-0
更新日期：1999-06-01 00:00:00
abstract：:Mouse brain myelin consists of a continuum of particles of different densities, as shown by sucrose density gradient centrifugation. In normal animals most of the material (65 per cent) is concentrated between 0.6 and 0.7 M sucrose (the maximum being found at 0.66 M sucrose, corresponding to 23 per cent). The density ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(77)80213-7
更新日期：1977-01-01 00:00:00
abstract：:Hypertension is the leading cause of preventable mortality worldwide, contributing to over 9 million deaths per annum, predominantly owing to cardiovascular disease. The association of obesity, physical inactivity and alcohol with elevated blood pressure (BP) is firmly established. Weight loss or other dietary strateg...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2020.03.016
更新日期：2020-06-01 00:00:00
abstract：:We present here, a new method for coupling sulfhydryl groups (SH) to low-density lipoprotein (LDL) surface. This method uses homocysteine thiolactone (HCTL) which reacts with lysine residues in a very mild manner, and permits the selection of the number of SH bound per LDL. Under our experimental conditions (8 SH/LDL)...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(86)80166-3
更新日期：1986-05-01 00:00:00
abstract：:Human delta-aminolevulinic acid dehydratase (ALA-D) was purified 9 000-fold by salt precipitation, ion-exchange chromatography and gel filtration. These methods resulted into an electrophoretically and immunologically pure protein. The optimum pH of the enzyme is 6.6 and its Km with ALA : 4.8 X 10(-4) M. The enzymatic...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(80)80256-2
更新日期：1979-01-01 00:00:00
abstract：:The effects of DNA oligonucleotides complementary to potato spindle tuber viroid (PSTVd) on viroid infection were investigated. The oligonucleotides were used to form hybrids with PSTVd in the infection mixture. A 75% reduction of viroid infection was found when an oligonucleotide complementary to nucleotides 79-110 o...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(93)90026-o
更新日期：1993-01-01 00:00:00
abstract：:Isopentenyl adenosine derivatives can be found next to the anticodon (position 37) in tRNA from both the Bacteria and Eucarya domains. These modified nucleosides improve the efficiency of tRNA in translation, can increase and decrease translational fidelity, and make the tRNA less codon context sensitive. In bacteria ...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/0300-9084(94)90044-2
更新日期：1994-01-01 00:00:00
abstract：:Unspliced human immunodeficiency virus-1 (HIV-1) mRNA is capped and therefore can be translated via conventional scanning mechanism. In addition, its 5' untranslated region (5'UTR) is thought to function as an internal ribosome entry site (IRES) during G2/M-phase of cell cycle or when cap-dependent translation is inhi...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2015.12.004
更新日期：2016-02-01 00:00:00
abstract：:We isolated and purified the main lipids of the rat sciatic nerve. After methanolysis, fatty acids were isolated and purified by thin layer chromatography, and studied by gas chromatography. C 16 and C 18 fatty acids are the most abundant. Among the long-chain fatty acids, arachidonic acid (20:4) is present in some li...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(78)80202-8
更新日期：1978-01-01 00:00:00
abstract：:The regulation of transcription of the pckA gene coding for phosphoenolpyruvate carboxykinase in Escherichia coli was analysed by site-directed mutagenesis of the promoter region and measurement of in vitro transcription initiation. Mutation of the guanine residue at position -14 to either cytosine or thymine was foun...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(99)80052-2
更新日期：1999-03-01 00:00:00
abstract：:NADH cytochrome b5 oxidoreductase (Ncb5or) protects β-cells against oxidative stress and lipotoxicity. The predominant phenotype of lean Ncb5or-null mouse is insulin-dependent diabetes due to β-cell death. This suggests the putative role of NCB5OR polymorphism in human diabetes. Therefore, we aimed to investigate the ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2013.03.004
更新日期：2013-07-01 00:00:00
abstract：:A 3-D model of the tyrosylable tRNA-like domain of the genomic brome mosaic virus RNAs was built by computer modelling based on solution probing of the molecule with different chemical and enzymatic reagents. This model encompasses four major structural domains, including two peculiar substructures oriented perpendicu...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/0300-9084(93)90014-j
更新日期：1993-01-01 00:00:00
abstract：:The eukaryotic ribosomal protein S15 is a key component of the decoding site in contrast to its prokaryotic counterpart, S19p, which is located away from the mRNA binding track on the ribosome. Here, we determined the oligopeptide of S15 neighboring the A site mRNA codon on the human 80S ribosome with the use of mRNA ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2010.02.031
更新日期：2010-07-01 00:00:00
abstract：:Regeneration is an adaptive phenomenon with wide biological implications spread heterogeneously in almost all the organism including human beings. The ability of regeneration varies from species to species for its complexity. Epimorphic regeneration of zebrafish caudal fin tissue is the most widely studied regeneratio...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2020.05.014
更新日期：2020-08-01 00:00:00
abstract：:Poly(ADP-ribosyl)ation is a posttranslational protein modification significant for genomic stability and cell survival in response to DNA damage. Poly(ADP-ribosyl)ation is catalyzed by poly(ADP-ribose)polymerases (PARPs). Among the 17 members of the PARP family, PARP-1 and PARP-2 are described as enzymes whose catalyt...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2013.01.007
更新日期：2013-06-01 00:00:00
