Abstract:
:The 250-kDa sialoglycoprotein of bovine erythrocyte membranes, GP-2, has been found to be an exceptionally rich source of branched sialo-oligosaccharides of poly-N-acetyllactosamine (I antigen) type with receptor activity for the human pathogen Mycoplasma pneumoniae. Desialylated GP-2 is the most potent I-active substance thus far tested. Since this glycoprotein is hydrophobic and can be readily re-incorporated into cell membranes, it should be useful in future studies of the mechanism of production of autoantibodies to the I antigen which commonly arise following human infection with M. pneumoniae.
journal_name
Biosci Repjournal_title
Bioscience reportsauthors
Feizi T,Gooi HC,Loomes LM,Suzuki Y,Suzuki T,Matsumoto Mdoi
10.1007/BF01128815subject
Has Abstractpub_date
1984-09-01 00:00:00pages
743-9issue
9eissn
0144-8463issn
1573-4935journal_volume
4pub_type
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journal_title:Bioscience reports
pub_type: 杂志文章,评审
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更新日期:2015-04-16 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2007-06-01 00:00:00
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pub_type: 杂志文章,meta分析
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journal_title:Bioscience reports
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