Immunological visualization of 5-methylcytosine-rich regions in Indian Muntjac metaphase chromosomes.

abstract：:Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardioprotective efficacy of hispidin has not yet been investigated. In the present study, we investigated the protective ef...

journal_title：Experimental cell research

authors： Kim DE,Kim B,Shin HS,Kwon HJ,Park ES

更新日期：2014-10-01 00:00:00

abstract：:At the onset of mitosis in higher eukaryotic cells, the nuclear envelope and its components including subunits of the nuclear pore complexes are disassembled, and these are reassembled toward the end of mitosis. We have studied the role of protein phosphorylation in this process, by investigating the phosphorylation s...

journal_title：Experimental cell research

authors： Ganeshan R,Parnaik VK

更新日期：2000-11-25 00:00:00

abstract：:In order to test the existence of mechanical coupling between the rotational movements of two adjacent nuclei, we prepared binucleate 3T3 cells and observed their nuclear movements by near infrared microscopy and recorded them with time-lapse video techniques. We found that 49 out of 110 (44%) of the selected binuclea...

journal_title：Experimental cell research

authors： Paddock SW,Albrecht-Buehler G

更新日期：1986-09-01 00:00:00

abstract：:In many animals, the germ line develops from a distinct mitochondria-rich region of embryonic cytoplasm called the germ plasm. However, the protein composition of germ plasm and its formation remain poorly understood, except in Drosophila. Here, we show that Xpat, a recently identified protein component of Xenopus ger...

journal_title：Experimental cell research

authors： Hames RS,Hames R,Prosser SL,Euteneuer U,Lopes CA,Moore W,Woodland HR,Fry AM

更新日期：2008-02-01 00:00:00

abstract：:Mps-one-binder (Mob) proteins play a crucial role in yeast cytokinesis. After cloning two Mob1-like genes, MsMob1-A and MsMob1-B from alfalfa (Medicago sativa L.) we show that, although they are constitutively expressed in roots, stems, leaves, flowers and pods, their transcripts and proteins are mostly produced in ac...

journal_title：Experimental cell research

authors： Citterio S,Piatti S,Albertini E,Aina R,Varotto S,Barcaccia G

更新日期：2006-04-15 00:00:00

abstract：:Hypoxic conditions are common in solid tumors and have a significant effect on tumor progression, therapeutic and prognosis. Long noncoding RNAs (lncRNAs) are longer than 200 nucleotides and cannot be translated into proteins, which play important roles in some diseases including cancer. Although previous analysis hav...

journal_title：Experimental cell research

authors： Shen Y,Liu Y,Sun T,Yang W

更新日期：2017-09-15 00:00:00

abstract：:In multiple myeloma, which commonly depends on interleukin 6, IL-6, survival signaling induced by this cytokine is largely mediated by activation of STAT3. Interferon alpha (IFNalpha) treatment of cell lines derived from multiple myeloma or of myeloma tumor cells ex vivo leads to apoptosis. In this study we demonstrat...

journal_title：Experimental cell research

authors： Thyrell L,Arulampalam V,Hjortsberg L,Farnebo M,Grandér D,Pokrovskaja Tamm K

更新日期：2007-11-15 00:00:00

abstract：:HALF1 (human activator of liver function 1) is a closed DNA duplex implicated in reversion of rat dedifferentiated C2 hepatoma cells to a well-differentiated state. A copy of HALF1 is found in high-molecular-weight DNA in the human genome. The genomic equivalent of HALF1 and its flanking sequences [gH(5'-3') fragment]...

journal_title：Experimental cell research

authors： Boccaccio C,Meunier-Rotival M,Deschatrette J

更新日期：1994-07-01 00:00:00

abstract：:Expression of the metastasis suppressor NME1 in melanoma is associated with reduced cellular motility, invasion, and metastasis, but mechanisms underlying these activities are not completely understood. Herein we report a novel mechanism through which NME1 drives formation of large, stable focal adhesions (FAs) in mel...

journal_title：Experimental cell research

authors： Leonard MK,Novak M,Snyder D,Snow G,Pamidimukkala N,McCorkle JR,Yang XH,Kaetzel DM

更新日期：2019-01-01 00:00:00

abstract：:Autophagy is a major catabolic process allowing the renewal of intracellular organelles by which cells maintain their homeostasis. We have previously shown that autophagy is controlled by two transduction pathways mediated by a heterotrimeric Gi3 protein and phosphatidylinositol 3-kinase activities in the human colon ...

journal_title：Experimental cell research

authors： Bauvy C,Gane P,Arico S,Codogno P,Ogier-Denis E

更新日期：2001-08-15 00:00:00

abstract：:Recent reports suggest that several viruses, besides human immunodeficiency virus, induce apoptosis in infected cells. We report here that Sendai virus or Herpes simplex virus type 1 (HSV-1), two potent inducers of interferon-alpha, caused cell death in a consistent number of human peripheral blood mononuclear cells. ...

journal_title：Experimental cell research

authors： Tropea F,Troiano L,Monti D,Lovato E,Malorni W,Rainaldi G,Mattana P,Viscomi G,Ingletti MC,Portolani M

更新日期：1995-05-01 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) are needed for white matter repair after various brain injury. Means that promote OPC functions could benefit white matter recovery after injury. Chemokine CXCL12 and endothelial progenitor cells (EPCs) both have been shown to promote remyelination. We hypothesize that the benefi...

journal_title：Experimental cell research

authors： Yuan F,Chang S,Luo L,Li Y,Wang L,Song Y,Qu M,Zhang Z,Yang GY,Wang Y

更新日期：2018-06-15 00:00:00

abstract：:The development of hepatocellular carcinoma (HCC) is strongly associated with chronic inflammation. p66Shc is an oxidase previously shown to promote androgen-independent cell growth through generation of reactive oxygen species. However, the importance and biologic functions of p66Shc in HCC are unclear. The clinical ...

journal_title：Experimental cell research

authors： Huang P,Feng X,Zhao Z,Yang B,Fang T,Guo M,Xia J

更新日期：2019-10-15 00:00:00

abstract：:CIN85 is a multidomain protein that associates with receptors carrying tyrosine kinase domains. Here we report that it is also a component of the signaling complex associated with tumor necrosis factor receptor 1 (TNFR1), which lacks a tyrosine kinase domain. This was established by showing that CIN85 was co-precipita...

journal_title：Experimental cell research

authors： Narita T,Nishimura T,Yoshizaki K,Taniyama T

更新日期：2005-03-10 00:00:00

abstract：:This paper describes the preparation of lung acellular alveolar matrix fragments and culture of rat type II pneumocytes directly on the alveolar epithelial basement membrane, thereby permitting study of the effect of lung basement membrane on the morphology and function of type II cells. Collagen types I, III, IV and ...

journal_title：Experimental cell research

authors： Lwebuga-Mukasa JS,Ingbar DH,Madri JA

更新日期：1986-02-01 00:00:00

abstract：:Hydrogen peroxide is more toxic to mammalian cells at 37 degrees C than 0 degree C at all concentrations studied. Histone-free nuclei (nucleoids) extracted from treated cells have a reduced ability to maintain positive DNA supercoiling, with the maximum effect at the higher temperature. Prior exposure of cells to sodi...

journal_title：Experimental cell research

authors： Vaughan AT,Gordon DJ

更新日期：1992-10-01 00:00:00

abstract：:As a widely used anti-bacterial agent and a metabolic inhibitor as well as AMP-activated protein kinase (AMPK) activator, berberine (BBR) has been shown to cross the blood-brain barrier. Its efficacy has been investigated in various disease models of the central nervous system. Neurite outgrowth is critical for nervou...

journal_title：Experimental cell research

authors： Lu J,Cao Y,Cheng K,Xu B,Wang T,Yang Q,Yang Q,Feng X,Xia Q

更新日期：2015-06-10 00:00:00

abstract：:Total epidermal keratinocytes are a heterogeneous population of cells, including undifferentiated stem/progenitor cells (EpSPs) and their more differentiated progeny (Non-SP cells). Our previous in vivo data showed that EpSPs enhanced blood flow restoration when injected into an ischemic limb, whereas Non-SP cells had...

journal_title：Experimental cell research

authors： Oberley CC,Gourronc F,Hakimi S,Riordan M,Bronner S,Jiao C,Dunnwald M

更新日期：2008-02-15 00:00:00

abstract：:Increased protein aggregation and altered cell signaling accompany many neurodegenerative diseases including Huntington's disease (HD). Cell stress is counterbalanced by signals mediating cell repair but the identity of these are not fully understood. We show here that the mammalian target of rapamycin (mTOR) pathway ...

journal_title：Experimental cell research

authors： Hyrskyluoto A,Reijonen S,Kivinen J,Lindholm D,Korhonen L

更新日期：2012-01-01 00:00:00

abstract：:In this study, we examined the role(s) of syndecan-4 in regulating the formation of an actin geodesic dome structure called a cross-linked actin network (CLAN) in which syndecan-4 has previously been localized. CLANs have been described in several different cell types, but they have been most widely studied in human t...

journal_title：Experimental cell research

authors： Filla MS,Clark R,Peters DM

更新日期：2014-10-01 00:00:00

abstract：:The coxsackie- and adenovirus receptor (CAR) is a transmembrane protein belonging to the immunoglobulin superfamily. The function of CAR as a virus receptor has been extensively analyzed, while its physiological role and expression pattern in adult tissues have remained less clear. CAR associates with epithelial tight...

journal_title：Experimental cell research

authors： Raschperger E,Thyberg J,Pettersson S,Philipson L,Fuxe J,Pettersson RF

更新日期：2006-05-15 00:00:00

abstract：:Germ cells were isolated from mouse fetal gonads 11 1/2-16 1/2 days post coitum (dpc), and exposed to various methods of in vitro culture. From 13 1/2 dpc onwards, both male and female germ cells survived well at 37 degrees C for several days. During the culture period the proportion of female germ cells in meiosis in...

journal_title：Experimental cell research

authors： De Felici M,McLaren A

更新日期：1983-04-01 00:00:00

abstract：:Blood vessels are one of the major routes for the dissemination of cancer cells. Malignant tumors release growth factors such as vascular endothelial growth factor(VEGF) to induce angiogenesis, thereby promoting metastasis. Here, we report that The Drosophila Eyes Absent Homologue 1 (EYA1), which is overexpressed in c...

journal_title：Experimental cell research

authors： Cai S,Cheng X,Liu Y,Lin Z,Zeng W,Yang C,Liu L,Chukwuebuka OA,Li W

更新日期：2018-06-01 00:00:00

abstract：:Previous studies have shown that ascorbic acid increases both the total surface acetylcholine receptor (AChR) expression and the mRNA for the alpha-subunit of this receptor in myotubes of cloned L5 muscle cultures. Since ascorbic acid increases collagen synthesis in fibroblasts, we studied the effect of ascorbic acid ...

journal_title：Experimental cell research

authors： Liu E,Minor RR,Horovitz O,Wootton JA,Podleski TR,Salpeter MM

更新日期：1993-11-01 00:00:00

abstract：:A two-site radio-immunoassay for beta NGF demonstrated 5-10 pg of NGF in the normal, adult rat iris. Ciliarectomy or sympathectomy did not significantly alter the amount of NGF after 10 days. However, denervation including all sensory axons (stereotactic lesion distal to the trigeminal ganglion) increased the level to...

journal_title：Experimental cell research

authors： Ebendal T,Olson L,Seiger A

更新日期：1983-10-15 00:00:00

abstract：:The biosynthesis of type XI and type II collagens was examined using a stable rat chondrocyte cell line established by W. E. Horton et al. (1988, Exp. Cell Res. 178, 457-468.). These cells (IRC; immortalized rat chondrocytes) were created by transformation with a murine retrovirus carrying the v-myc and v-raf oncogene...

journal_title：Experimental cell research

authors： Oxford JT,Doege KJ,Horton WE Jr,Morris NP

更新日期：1994-07-01 00:00:00

abstract：:Following intratesticular injection of [3H]thymidine, spermatozoa were isolated from the caput and cauda epididymis of CD-1 mice. Quantitation of the amount of radiolabelled DNA in whole spermatozoa, sperm heads (nuclei) and sperm midpiece-tails (mitochondria) at time intervals 3-36 days postinjection demonstrated mit...

journal_title：Experimental cell research

authors： Hecht NB,Liem H

更新日期：1984-09-01 00:00:00

abstract：:Rat pheochromocytoma cells, PC12 cells, undergo differentiation in response to nerve growth factor (NGF). Although the Ras-MAP kinase signaling pathway has been shown to play a central role in the response to NGF, the precise mechanism which induces differentiation remains unclarified. Recently, several gamma-lactam-r...

journal_title：Experimental cell research

authors： Yao R,Osada H

更新日期：1997-08-01 00:00:00

abstract：:Formation of the neural tube is the morphological hallmark for development of the embryonic central nervous system (CNS). Therefore, neural tube development is a crucial step in the neurulation process. Slit/Robo signaling was initially identified as a chemo-repellent that regulated axon growth cone elongation, but it...

journal_title：Experimental cell research

authors： Wang G,Li Y,Wang XY,Han Z,Chuai M,Wang LJ,Ho Lee KK,Geng JG,Yang X

更新日期：2013-05-01 00:00:00

abstract：:Ataxia-telangiectasia mutated (ATM) and RAD3-related (ATR) are widely known as being central players in the mitotic DNA damage response (DDR), mounting responses to DNA double-strand breaks (DSBs) and single-stranded DNA (ssDNA) respectively. The DDR signalling cascade couples cell cycle control to damage-sensing and ...

journal_title：Experimental cell research

authors： Cooper TJ,Wardell K,Garcia V,Neale MJ

更新日期：2014-11-15 00:00:00