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Mitochondrial DNA is synthesized during meiosis and spermiogenesis in the mouse.

Abstract：

:Following intratesticular injection of [3H]thymidine, spermatozoa were isolated from the caput and cauda epididymis of CD-1 mice. Quantitation of the amount of radiolabelled DNA in whole spermatozoa, sperm heads (nuclei) and sperm midpiece-tails (mitochondria) at time intervals 3-36 days postinjection demonstrated mitochondrial DNA (mtDNA) is synthesized during meiosis and early spermiogenesis. mtDNA synthesis terminates in mid-spermiogenesis suggesting that the mitochondrial genome in spermatozoa has a half-life of at least 15 days.

journal_name

Exp Cell Res

journal_title

Experimental cell research

authors

Hecht NB,Liem H

doi

10.1016/0014-4827(84)90688-8

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

293-8

issue

1

eissn

0014-4827

issn

1090-2422

pii

0014-4827(84)90688-8

journal_volume

154

pub_type

杂志文章

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