Abstract：
:The effect of a fish lipid concentrate rich in eicosapentaenoic acid was studied in 107 subjects for periods up to 2 years. Ninety-two had heart disease or hyper-lipidaemia and 15 had no history of heart disease. Serum triglyceride levels were rapidly reduced, cholesterol fell more slowly but high density lipoprotein (HDL) cholesterol was increased. Bleeding time increased significantly and the consumption of glyceryl trinitrate (GTN) tablets decreased together with a reduction in anginal attacks. The data are consistent with a reduction in hepatic triglyceride synthesis rather than an increased rate of triglyceride clearance. Total and HDL cholesterol changes are suggestive of an enhanced removal of cholesterol from the tissues. Increased bleeding time and changes in GTN consumption are consistent with decreased platelet aggregation.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Saynor R,Verel D,Gillott Tdoi
10.1016/0021-9150(84)90003-0subject
Has Abstractpub_date
1984-01-01 00:00:00pages
3-10issue
1eissn
0021-9150issn
1879-1484pii
0021-9150(84)90003-0journal_volume
50pub_type
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