Metabolic responses following isoproterenol-induced myocardial infarction in arteriosclerotic breeder vs. non-arteriosclerotic virgin and ovariectomized female rats.

abstract：BACKGROUND AND AIMS:Diet and smoking expose the general population to cadmium (Cd), which is a toxic metal that accumulates in the arterial wall. In experimental studies, Cd causes reductions in proliferation of smooth muscle cells and cellular synthesis of procollagen. The aim of this study was to examine whether bloo...

journal_title：Atherosclerosis

authors： Fagerberg B,Borné Y,Sallsten G,Smith JG,Acosta S,Persson M,Melander O,Forsgard N,Gottsäter A,Hedblad B,Barregard L,Engström G

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Lowering low-density lipoprotein cholesterol (LDL-C) with statins reduces cardiovascular events and slows plaque progression. While this therapeutic approach has been reported to favorably modify plaque composition, this is not well characterized in humans. Also, the benefit of achieving LDL-C levels below cu...

journal_title：Atherosclerosis

authors： Kataoka Y,Hammadah M,Puri R,Duggal B,Uno K,Kapadia SR,Murat Tuzcu E,Nissen SE,Nicholls SJ

更新日期：2015-10-01 00:00:00

abstract：:Human aortic aneurysm is commonly characterized by the presence of advanced atherosclerosis associated with variable chronic adventitial inflammation. Histological examination of human aortic aneurysmal specimens revealed the presence of plasma cells and lymphoid aggregates in media and adventitia of the vessels. Immu...

journal_title：Atherosclerosis

authors： Yen HC,Lee FY,Chau LY

更新日期：1997-11-01 00:00:00

abstract：:It has been shown that triglyceride levels are one of the determinants of factor VII levels. In this study we have simultaneously evaluated, in a group of 102 healthy individuals, the different forms of factor VII, namely factor VII mass, factor VII coagulant activity, activated factor VII double-chain form and factor...

journal_title：Atherosclerosis

authors： Negri M,Arigliano PL,Talamini G,Carlini S,Manzato F,Bonadonna G

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Chronic ethanol consumption is associated with hypertension and atherosclerosis. Vascular oxidative stress is described as an important mechanism whereby ethanol predisposes to atherosclerosis. We hypothesized that nebivolol would prevent ethanol-induced hypertension and vascular oxidative stress. ...

journal_title：Atherosclerosis

authors： do Vale GT,Simplicio JA,Gonzaga NA,Yokota R,Ribeiro AA,Casarini DE,de Martinis BS,Tirapelli CR

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Diabetic patients are characterised by poorer prognosis and more cardiovascular complications compared with non-diabetic patients, which may be due to metabolic abnormalities and atherosclerotic plaque characteristics. METHODS:Patients with unstable angina pectoris were enrolled in the study and divided int...

journal_title：Atherosclerosis

authors： Feng T,Yundai C,Lian C,Zhijun S,Changfu L,Jun G,Hongbin L

更新日期：2010-12-01 00:00:00

abstract：:A Japanese group comprising 53 hyperlipidemic and 54 normolipidemic subjects was genotyped for DNA restriction fragment length polymorphisms (RFLPs) at the apo B gene locus. The polymorphisms with XbaI and PvuII were present at allelic frequencies of 0.04 (X1 allele) and 0.96 (X2 allele), 0.94 (P1 allele) and 0.06 (P2...

journal_title：Atherosclerosis

authors： Aburatani H,Matsumoto A,Itoh H,Yamada N,Murase T,Takaku F,Itakura H

更新日期：1988-07-01 00:00:00

abstract：:Extracellular-superoxide dismutase (EC-SOD) is the major SOD isozyme in the arterial wall and may be important for antioxidation capability of the vascular wall and normal vascular function. EC-SOD is expressed in various cell types in the vascular wall such as fibroblasts, smooth muscle cells and macrophages, and the...

journal_title：Atherosclerosis

authors： Adachi T,Hara H,Yamada H,Yamazaki N,Yamamoto M,Sugiyama T,Futenma A,Katagiri Y

更新日期：2001-12-01 00:00:00

abstract：:Five homozygous patients with familial hypercholesterolemia (FH) are described. Their serum cholesterol levels were between 603 and 907 mg/dl, with an average of 714 mg/dl. The mean value of serum cholesterol levels of the obligate heterozygous parents was 270 mg/dl. In the patient group, 87% of the serum cholesterol ...

journal_title：Atherosclerosis

authors： Cai HJ,Fan LM,Huang MG,Chen XY,Liu GQ,Chen Q

更新日期：1985-11-01 00:00:00

abstract：:Previous studies from this laboratory have shown that degradation of heparan sulphate proteoglycan by both living macrophages and macrophage lysosomal heparanase induces phenotypic change of vascular smooth muscle cells (SMC) from a high volume fraction of myofilaments (V(v)myo) to a low V(v)myo [Campbell et al. Exp C...

journal_title：Atherosclerosis

authors： Fitzgerald M,Hayward IP,Thomas AC,Campbell GR,Campbell JH

更新日期：1999-07-01 00:00:00

abstract：:The ultrastructure of the aortic intima and serum lipid levels in Fischer 344 rats were examined at the ages of 12, 18 and 24 months after feeding the animals an atherogenic diet (2% cholesterol, 0.25% sodium cholate, 5% beef fat) for 6 months. Structural changes in the intima were noticeable only at the age of 24 mon...

journal_title：Atherosclerosis

authors： Nakamura H,Izumiyama N,Nakamura K,Ohtsubo K

更新日期：1989-10-01 00:00:00

abstract：:The association between cigarette smoking and atherogenesis is well established. Inflammatory cells may participate in atherogenesis via activation of the NADPH oxidase and the subsequent production of reactive oxygen species (ROS), which exacerbates endothelial injury. However, little is known about the ability of ci...

journal_title：Atherosclerosis

authors： Dunn JS,Freed BM,Gustafson DL,Stringer KA

更新日期：2005-04-01 00:00:00

abstract：:Studies on carotid artery atherosclerosis have been performed in order to understand the high risk for cardiovascular disease in chronic renal failure (CRF). The purpose of this study was to evaluate the extent and nature of carotid artery atherosclerosis in patients with CRF. Of the 135 patients with CRF (52 +/- 11 y...

journal_title：Atherosclerosis

authors： Leskinen Y,Lehtimäki T,Loimaala A,Lautamatti V,Kallio T,Huhtala H,Salenius JP,Saha H

更新日期：2003-12-01 00:00:00

abstract：:We have previously demonstrated great benefit from anti-monocyte chemoattractant protein-1 (MCP-1) gene therapy by "systemic" transfer of an N-terminal deletion mutant of human MCP-1 (called 7ND) gene into skeletal muscle for treatment of restenosis and atherosclerosis. However, recent evidence suggests that "local" g...

journal_title：Atherosclerosis

authors： Nakano K,Egashira K,Ohtani K,Zhao G,Funakoshi K,Ihara Y,Sunagawa K

更新日期：2007-10-01 00:00:00

abstract：:The lecithin:cholesterol acyltransferase (LCAT) enzyme is responsible for the synthesis of cholesteryl esters in human plasma and plays a critical role in high density lipoprotein (HDL) metabolism. Genetic LCAT deficiency is a rare metabolic disorder characterized by low HDL cholesterol levels. This paper reviews the ...

journal_title：Atherosclerosis

authors： Calabresi L,Simonelli S,Gomaraschi M,Franceschini G

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that sleep duration is associated with total mortality in a U-shaped fashion. The purpose of the current study was to examine the relationship between self-reported sleep duration and carotid artery atherosclerosis in a Japanese population. METHODS:In 2009-2010, a total of 24...

journal_title：Atherosclerosis

authors： Abe T,Aoki T,Yata S,Okada M

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Using a nationwide epidemiological database, we aimed to clarify the association of fasting plasma glucose (FPG) with subsequent cardiovascular disease (CVD) risk among young adults. METHODS AND RESULTS:Medical records of 1,180,062 young adults (20-49 years old) without a prior history of CVD and w...

journal_title：Atherosclerosis

authors： Kaneko H,Itoh H,Kiriyama H,Kamon T,Fujiu K,Morita K,Michihata N,Jo T,Takeda N,Morita H,Yasunaga H,Komuro I

更新日期：2021-01-16 00:00:00

abstract：OBJECTIVE:Blood glucose fluctuations have been found to be relevant to the progression of atherosclerosis in patients with type 2 diabetes and to be more detrimental for the development of atherosclerosis than the sustained hyperglycemia. We aim at evaluating the effect of blunted daily acute glucose fluctuations by DP...

journal_title：Atherosclerosis

authors： Barbieri M,Rizzo MR,Marfella R,Boccardi V,Esposito A,Pansini A,Paolisso G

更新日期：2013-04-01 00:00:00

abstract：:Consumption of oily fish and fish oils is associated with protection against cardiovascular disease. Paradoxically, long-chain polyunsaturated fatty acids present in low-density lipoprotein (LDL) are suggested to be susceptible to oxidation. It is not clear whether eicosapentaenoic acid (EPA) and docosahexaenoic acid ...

journal_title：Atherosclerosis

authors： Mesa MD,Buckley R,Minihane AM,Yaqoob P

更新日期：2004-08-01 00:00:00

abstract：:In animal model studies, the uptake of chylomicron remnants after entering in the space of Disse occurs mainly by low-density lipoprotein (LDL) receptor and LDL receptor-related protein (LRP). In subjects, the relative importance of each one of these receptors for the clearance of chylomicron remnants is not fully und...

journal_title：Atherosclerosis

authors： Sposito AC,Santos RD,Hueb W,Ventura LI,Vinagre CC,Ramires JA,Maranhão RC

更新日期：2002-04-01 00:00:00

abstract：AIMS:The purpose of this study was to determine the relationship between higher-risk features of coronary plaque and serum levels of matrix metalloproteinase (MMP) family enzymes in the stable angina patients. METHODS AND RESULTS:In 36 patients, 75 coronary lesions were assessed by intravascular ultrasound. For each o...

journal_title：Atherosclerosis

authors： Kruk M,Kalińczuk L,Pregowski J,Przyłuski J,Janas J,Chmielak Z,Demkow M,Debski A,Ciszewski A,Otto B,Witkowski A,Ruzyłło W

更新日期：2007-10-01 00:00:00

abstract：:Methodological differences and variations in health care regulations among countries often preclude direct comparisons of cost-effectiveness studies. A projected risk model was applied, designed to determine the economic value in the United States of pravastatin in the secondary prevention of coronary heart disease (C...

journal_title：Atherosclerosis

authors： Muls E,Van Ganse E,Closon MC

更新日期：1998-04-01 00:00:00

abstract：:Chronic renal failure markedly accelerates atherogenesis in apolipoprotein E-deficient (apoE(-/-)) mice. To study the putative role of receptor for advanced glycation end products (RAGE) in development of uremic atherosclerosis, apoE(-/-) mice received intraperitoneal injections thrice weekly of a neutralizing murine ...

journal_title：Atherosclerosis

authors： Bro S,Flyvbjerg A,Binder CJ,Bang CA,Denner L,Olgaard K,Nielsen LB

更新日期：2008-12-01 00:00:00

abstract：:Ultrasound measurements are both surrogate markers and risk factors for atherosclerosis end points. Carotid intima-media thickness (IMT) is most commonly used, but ultrasound can also define structures in higher spatial dimensions, such as total plaque area (TPA) and total plaque volume (TPV). Because there are minima...

journal_title：Atherosclerosis

authors： Al-Shali K,House AA,Hanley AJ,Khan HM,Harris SB,Mamakeesick M,Zinman B,Fenster A,Spence JD,Hegele RA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Bisphenol A (BPA) levels have previously been associated with coronary heart disease (CHD). Since CHD is an atherosclerotic disease, we investigated if circulating levels of BPA and phthalate metabolites are related to atherosclerosis in a cross-sectional study. METHODS:In the population-based...

journal_title：Atherosclerosis

authors： Lind PM,Lind L

更新日期：2011-09-01 00:00:00

abstract：:The involvement of endothelium-derived hyperpolarizing factor (EDHF) in the protective effect of 17beta-estradiol was investigated on the phenylephrine-precontracted carotid artery from cholesterol fed rabbits. Animals were fed for 8 weeks as follows: control group, standard chow; (control+estradiol) group, standard c...

journal_title：Atherosclerosis

authors： Ghanam K,Ea-Kim L,Javellaud J,Oudart N

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To determine the association of circulating P-selectin with prevalent and incident peripheral artery disease (PAD), the ankle brachial index (ABI), and change in the ABI. METHODS:The Multi-Ethnic Study of Atherosclerosis (MESA) is a prospective population-based cohort study including 6814 European descent, A...

journal_title：Atherosclerosis

authors： Wassel CL,Berardi C,Pankow JS,Larson NB,Decker PA,Hanson NQ,Tsai MY,Criqui MH,Allison MA,Bielinski SJ

更新日期：2015-04-01 00:00:00

abstract：:The possible role of four candidate genes in lipid and lipoprotein response to diet was examined in 214 members of two large kibbutz settlements in Israel. Four site polymorphisms (signal peptide insertion/deletion, XbaI, EcoRI and MspI) of the apo B gene, the common apo E genotypes, three common mutations (T-93G, S44...

journal_title：Atherosclerosis

authors： Friedlander Y,Leitersdorf E,Vecsler R,Funke H,Kark J

更新日期：2000-09-01 00:00:00

abstract：:To investigate the association between time from diagnosis of type 2 diabetes to initiation of insulin therapy (pre-exogenous insulin period) and intima-media thickness (IMT) of the common carotid artery (CCA), a cross-sectional analysis was conducted among 98 males and 193 females (90% Hispanic) with type 2 diabetes,...

journal_title：Atherosclerosis

authors： Zheng L,Buchanan TA,Hodis HN,Li Y,Torres M,Mack WJ

更新日期：2003-10-01 00:00:00

abstract：RATIONALE:Obstructive sleep apnea results in nocturnal intermittent hypoxia (IH) as a main trigger for cardiovascular morbidity, including atherosclerosis. IH induces hemodynamic, hormono-metabolic and also immuno-inflammatory alterations that could differentially contribute to atherosclerosis. Our study aimed at exami...

journal_title：Atherosclerosis

authors： Arnaud C,Poulain L,Lévy P,Dematteis M

更新日期：2011-12-01 00:00:00