Plasma proprotein convertase subtilisin-kexin type 9 does not change during 24h insulin infusion in healthy subjects and type 2 diabetic patients.

abstract：:The effect of cage population density on plasma lipids and the development of atherosclerosis was examined in female C57BL/6 mice. Mice were housed at a density of one, two or five animals per cage and fed an atherogenic diet for 28 weeks. Subsequently, the animals were bled, sacrificed, the hearts removed and the ext...

journal_title：Atherosclerosis

authors： Lin AH,Castle CK,Melchior GW,Marotti KR

更新日期：1995-05-01 00:00:00

abstract：:Microsomal triglyceride transfer protein (MTP) is a lipid transfer protein that is required for the assembly and secretion of very low density lipoproteins (VLDL) by the liver and chylomicrons by the intestine. The common G-493T polymorphism of the MTP promoter has been shown to be associated with decreased plasma LDL...

journal_title：Atherosclerosis

authors： Couture P,Otvos JD,Cupples LA,Wilson PW,Schaefer EJ,Ordovas JM

更新日期：2000-02-01 00:00:00

abstract：:This study assessed the efficacy of rosuvastatin for reducing plasma low-density lipoprotein (LDL) cholesterol after 18 weeks of open-label, forced titration in patients with homozygous familial hypercholesterolaemia (hoFH) and compared the efficacy of rosuvastatin 80 mg and atorvastatin 80 mg. Forty-four patients age...

journal_title：Atherosclerosis

authors： Marais AD,Raal FJ,Stein EA,Rader DJ,Blasetto J,Palmer M,Wilpshaar W

更新日期：2008-03-01 00:00:00

abstract：:Genome-wide association studies (GWASs) have identified several risk loci for coronary artery calcification. Four single-nucleotide polymorphisms (SNPs, rs1537370, rs1333049, rs2026458 and rs9349379) were associated with coronary artery calcification with P values less than 5 × 10(-8) in GWASs. It is unclear if these ...

journal_title：Atherosclerosis

authors： Zhang Y,Wang L,Zhang Z,Zhang Z,Zhou S,Cao L,Cai B,Liu K,Bai W,Xie X,Fan W,Liu X,Lu G,Xu G

更新日期：2015-08-01 00:00:00

abstract：INTRODUCTION:Emerging data suggests that 3-dimensional (D) ultrasound (US) may provide us with a new tool for the identification of the vulnerable carotid plaque. METHODS:A systematic review of the PubMed, Scopus and Cochrane databases regarding the reproducibility and effectiveness of 3D US in evaluation of carotid p...

journal_title：Atherosclerosis

authors： Makris GC,Lavida A,Griffin M,Geroulakos G,Nicolaides AN

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiovascular disease (CVD), including coronary artery disease and stroke/peripheral artery disease, is less commonly reported than venous thromboembolism in subjects with antiphospholipid antibodies (aPLs) and little is known about the association of CVD with adjusted Global AntiphosPholipid Syndr...

journal_title：Atherosclerosis

authors： Di Minno MND,Scalera A,Tufano A,Ambrosino P,Bettiol A,Silvestri E,Emmi G,Prisco D

更新日期：2018-11-01 00:00:00

abstract：:The ability of triglyceride (TG)-rich lipoproteins from apolipoprotein (apo) E2 heterozygote, apo E3/2 which is relatively common, to stimulate cholesteryl ester synthesis in human monocyte-derived macrophages was studied to clarify the atherogenicity of apo E3/2. Twenty-three subjects were randomly sampled from our h...

journal_title：Atherosclerosis

authors： Saito M,Eto M,Makino I

更新日期：1997-02-28 00:00:00

abstract：BACKGROUND AND AIMS:Atherosclerosis is a chronic inflammatory disease of medium and large vessels and is typically characterized by the predominant accumulation of low-density lipoprotein (LDL)-cholesterol inside macrophages that reside in the vessel walls. Previous studies clearly demonstrated an association specifica...

journal_title：Atherosclerosis

authors： Jeurissen MLJ,Walenbergh SMA,Houben T,Gijbels MJJ,Li J,Hendrikx T,Oligschlaeger Y,van Gorp PJ,Binder CJ,Donners MMPC,Shiri-Sverdlov R

更新日期：2016-12-01 00:00:00

abstract：:To asses the relationship between fibrinogen, factor VII coagulant (VIIc) activity and extent of coronary artery disease, we studied 43 white males shown to have greater than 50% stenosis of at least one major coronary artery. Thirty six had a definite history of myocardial infarction at least 3 months earlier and wer...

journal_title：Atherosclerosis

authors： Broadhurst P,Kelleher C,Hughes L,Imeson JD,Raftery EB

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:The prolactin regulatory element binding (PREB) protein is a transcriptional factor that regulates prolactin promoter activity in rat anterior pituitary. It is expressed not only in the anterior pituitary but also in the cardiovascular system, including in human umbilical vascular endothelial cells (HUVECs). ...

journal_title：Atherosclerosis

authors： Murao K,Imachi H,Yu X,Muraoka T,Hosami N,Dobashi H,Ishida T

更新日期：2009-11-01 00:00:00

abstract：:Oxidized low-density lipoproteins (LDL) impair endothelium-dependent dilation and constrict arteries. This study examined possible relation of the circulating plasma levels of Ox-LDL to coronary spastic angina (CSA). The plasma levels of Ox-LDL were measured by ELISA in 37 consecutive patients with CSA and normal coro...

journal_title：Atherosclerosis

authors： Kugiyama K,Sugiyama S,Soejima H,Kawano H,Sakamoto T,Takazoe K,Ogawa H,Doi H,Yasue H

更新日期：2001-02-01 00:00:00

abstract：:HMG-CoA reductase inhibitor drugs or 'statins' have been shown to effectively reduce plasma total cholesterol (CHOL), CHOL associated with low-density-lipoprotein (LDL), and triglycerides (TG). In addition, slight elevations in HDL-CHOL are also typically observed. Poloxamer 407 (P-407), a nonionic surfactant, effecti...

journal_title：Atherosclerosis

authors： Johnston TP,Baker JC,Hall D,Jamal S,Palmer WK,Emeson EE

更新日期：2000-04-01 00:00:00

abstract：:To study the association of alcohol consumption and lipid-based cardiovascular risk factors among middle-age women, cross-sectional analysis among 274 middle-aged healthy women with different drinking habits and a follow-up analysis of alcoholic women during abstinence was performed. Serum total cholesterol, low and h...

journal_title：Atherosclerosis

authors： Sillanaukee P,Koivula T,Jokela H,Pitkäjärvi T,Seppä K

更新日期：2000-10-01 00:00:00

abstract：:We previously demonstrated that hyperbaric oxygen (HBO) treatment inhibits diet-induced atherosclerosis in New Zealand White rabbits. In the present study we investigate the mechanisms that might be involved in the athero-protective effect of HBO treatment in a well-accepted model of atherosclerosis, the apoE knockout...

journal_title：Atherosclerosis

authors： Kudchodkar BJ,Pierce A,Dory L

更新日期：2007-07-01 00:00:00

abstract：:Increased oxidative stress (SOX), inflammation and prevalence of cardiovascular disease (CVD) have been reported in end-stage renal disease (ESRD), but their associations with kynurenine (KYN) pathway activation remain unknown. We determined the plasma concentrations of tryptophan (TRP), KYN, 3-hydroxykynurenine (3-HK...

journal_title：Atherosclerosis

authors： Pawlak K,Domaniewski T,Mysliwiec M,Pawlak D

更新日期：2009-05-01 00:00:00

abstract：:In previous works, it has been evidenced that lipoperoxidative injury to macrophages caused by oxidatively modified low-density lipoprotein (O-LDL) plays an important role in foam cell formation, and that PSK, a protein bound polysaccharide extracted from the class Basidiomycetes Coriolus Versicolor, can protect macro...

journal_title：Atherosclerosis

authors： Yuan C,Mei Z,Liu S,Yi L

更新日期：1996-08-02 00:00:00

abstract：:The effects of administration of pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on hepatic cholesterol 7 alpha-hydroxylase and acyl-coenzyme A: cholesterol acyltransferase (ACAT) activities and bile lipid secretion were investigated in Syrian golden hamsters. Continuous administrat...

journal_title：Atherosclerosis

authors： Hayashi K,Noshiro M,Kurushima H,Kuga Y,Nomura S,Ohkura Y,Ohtani H,Kurokawa J,Tanaka K,Yasunobu Y

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Increased arterial stiffness is associated with greater risk of cardiovascular events and mortality. However, in patients with peripheral arterial disease (PAD) who have severe atherosclerotic disorder or risk clustering, the major determinants of increased stiffness have been not clarified. METHODS:This st...

journal_title：Atherosclerosis

authors： Makita S,Matsui H,Naganuma Y,Abiko A,Tamada M,Nakamura M

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Statins inhibit cholesterol synthesis but can upregulate cholesterol absorption, with higher doses producing larger effects. Ezetimibe inhibits cholesterol absorption but also upregulates synthesis. We tested whether ezetimibe added to on-going statin therapy would be most effective in lowering LDL-cholestero...

journal_title：Atherosclerosis

authors： Thongtang N,Lin J,Schaefer EJ,Lowe RS,Tomassini JE,Shah AK,Tershakovec AM

更新日期：2012-12-01 00:00:00

abstract：:Hypothyroidism is associated with hypercholesterolemia and increased risk for atherosclerotic disease. The European badger exhibits large seasonal changes in thyroid activity and the annual minimum of plasma thyroxine level in this species occurs at the same period of the year (i.e. late fall) as a pronounced hypercho...

journal_title：Atherosclerosis

authors： Laplaud PM,Beaubatie L,Maurel D,Catanzano G

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysfunctional high-density lipoprotein (HDL) is a risk factor for cardiovascular disease (CVD) beyond HDL concentrations. Recently, a novel method has been introduced to measure LOX-1 ligand containing apolipoprotein AI (LAA), which is an indicator of various types of modified HDL with binding capac...

journal_title：Atherosclerosis

authors： Hirata A,Kakino A,Okamura T,Usami Y,Fujita Y,Kadota A,Fujiyoshi A,Hisamatsu T,Kondo K,Segawa H,Sawamura T,Miura K,Ueshima H,SESSA Research Group.

更新日期：2020-11-01 00:00:00

abstract：:Cholesteryl ester transfer from solid-phase bound HDL to endogenous plasma HDL or VLDL/LDL was determined in 50 patients with primary disorders of lipid metabolism and 27 normolipidemic subjects. Transfer to the plasma HDL pool was significantly reduced in familial hypercholesterolemia, familial combined hyperlipidemi...

journal_title：Atherosclerosis

authors： Sparks DL,Frohlich J,Lacko AG,Pritchard PH

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Micro-particles (MP) are secreted by various cells. Their biological roles in health and in disease remain unknown. Here we describe formation of MP in the process of ABCA1-dependent cholesterol efflux in different cell types. METHODS:The ATP-binding cassette transporter, subfamily A, member 1 (ABC...

journal_title：Atherosclerosis

authors： Hafiane A,Genest J

更新日期：2017-02-01 00:00:00

abstract：:Atherosclerosis causing cardiovascular disease is the most common cause of death in the developed world. Early precursors of vascular changes - subclinical atherosclerosis - warrant special attention as this process can be stabilized or even reversed if treated in time. Sonographic Intima Media Thickness measurement o...

journal_title：Atherosclerosis

authors： Dalla Pozza R,Ehringer-Schetitska D,Fritsch P,Jokinen E,Petropoulos A,Oberhoffer R,Association for European Paediatric Cardiology Working Group Cardiovascular Prevention.

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Genetic variation in CC-chemokine receptor-2 (CCR2) and -5 (CCR5), and their common haplotypes, acting through inflammatory responses, may affect atherosclerosis and risk of coronary heart disease (CHD). METHOD AND RESULTS:We examined seven common variants in the CCR2 and CCR5 loci and risk of CHD among wome...

journal_title：Atherosclerosis

authors： Pai JK,Kraft P,Cannuscio CC,Manson JE,Rexrode KM,Albert CM,Hunter D,Rimm EB

更新日期：2006-05-01 00:00:00

abstract：INTRODUCTION:The possible cause of accelerated atherosclerosis in NAFLD may be the relationship with the MetS and its components. Our primary goal was to evaluate the relationship between NAFLD and subclinical atherosclerosis in adult male patients between 20 and 40 years of age. Moreover, we aimed to investigate the c...

journal_title：Atherosclerosis

authors： Ozturk K,Uygun A,Guler AK,Demirci H,Ozdemir C,Cakir M,Sakin YS,Turker T,Sari S,Demirbas S,Karslıoğlu Y,Saglam M

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Common variants at the 2q36.3-IRS1 locus are associated with insulin resistance (IR), type 2 diabetes (T2D) and coronary artery disease (CAD) in large-scale association studies. We tested the hypothesis that variants at this locus are associated with subclinical atherosclerosis traits. METHODS:We studied 274...

journal_title：Atherosclerosis

authors： Lim S,Hong J,Liu CT,Hivert MF,White CC,Murabito JM,O'Donnell CJ,Dupuis J,Florez JC,Meigs JB

更新日期：2013-07-01 00:00:00

abstract：:Pressure recordings in 120 patients, aged 0-35 years, undergoing operation for coarctation of the aorta, show a slow but steady rise in both systolic and diastolic peak pressures, the highest peak registered being in patients aged 16-18 years. The finding of significant morphological changes in the aorta in this age g...

journal_title：Atherosclerosis

authors： Anyanwu E,Dittrich H,Jelesijević V,Drüen B,Krefting ER,Höhling H

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Mitochondrial damage and augmented production of reactive oxygen species (ROS) may represent an intermediate step by which hypercholesterolemia exacerbates atherosclerotic lesion formation. METHODS:To test this hypothesis, in mice with severe but genetically reversible hypercholesterolemia (i.e. th...

journal_title：Atherosclerosis

authors： Vilne B,Skogsberg J,Foroughi Asl H,Talukdar HA,Kessler T,Björkegren JLM,Schunkert H

更新日期：2017-12-01 00:00:00

abstract：:Lipoprotein dynamics are complex during the postprandial state. A significant rise in chylomicron concentration is associated with increased competition for LPL with VLDL particles. This results in an increased concentration of large VLDL. The concentration of small VLDL is reduced as a result of diminished conversion...

journal_title：Atherosclerosis

authors： Hugh P,Barrett R

更新日期：1998-12-01 00:00:00