Presynaptic involvement in frequency facilitation in the hippocampal slice.

abstract：:CaCl2-induced myelopathy was produced in rats by the application of a solution of CaCl2 to exposed leptomeninges of lumbosacral spinal cord. Equal lengths of remote cervical and lumbar cord were removed at intervals following Ca2+ application. The total Ca2+ in tissue from lumbar cord was significantly elevated over a...

journal_title：Neuroscience letters

authors： Happel RD,Banik NL,Balentine JD,Hogan EL

更新日期：1984-08-31 00:00:00

abstract：:Deimination is a post-translational modification of proteins in which selected arginine amino acids are enzymatically converted to citrullines. Using dual-color immunofluorescence, the present study is the first to examine the frontal cortex of patients with Alzheimer's disease (AD) versus age-matched controls with an...

journal_title：Neuroscience letters

authors： Nicholas AP

更新日期：2013-06-17 00:00:00

abstract：:To clarify the possible role of in the in vivo toxic effects of 6-hydroxydopamine (6-OHDA), especially caspase activations, we examined its effects on striatal lipid peroxidation (LPO) and caspase activations in 6-OHDA-lesioned mice. Both dopamine (DA) levels and DA turnover were significantly changed by the 6-OHDA i....

journal_title：Neuroscience letters

authors： Tanaka K,Ogawa N,Asanuma M

更新日期：2006-12-20 00:00:00

abstract：:Eight male rats were deprived of rapid eye movement (REM) sleep for 6 days by means of a cuff pedestal which makes it possible to use the animal as its own control. In order to obtain access to food, the rat had to jump from its pedestal to a strip of wire mesh suspended from the ceiling of the deprivation chamber. Th...

journal_title：Neuroscience letters

authors： Elomaa E,Johansson GG

更新日期：1986-01-02 00:00:00

abstract：:The distribution of Purkinje cells projecting to the descending vestibular nucleus was studied in lobule IX (uvula) of the cat by the retrograde wheat germ agglutinin-horseradish peroxidase method. In the transverse plane labeled Purkinje cells were seen diffusely within 1.0 mm from the midline and densely for 250-500...

journal_title：Neuroscience letters

authors： Matsushita M,Wang CL

更新日期：1986-05-23 00:00:00

abstract：:Neuromuscular electrical stimulation (NMES) increases the excitability of corticospinal (CS) pathways by altering circuits in motor cortex (M1). How NMES affects circuits interposed between the ascending afferent volley and descending CS pathways is not known. Presently, we hypothesized that short-latency afferent inh...

journal_title：Neuroscience letters

authors： Mang CS,Bergquist AJ,Roshko SM,Collins DF

更新日期：2012-10-31 00:00:00

abstract：:Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patc...

journal_title：Neuroscience letters

authors： Bigiani A,Roper SD

更新日期：1994-08-01 00:00:00

abstract：:In the rat the response of suprachiasmatic nucleus neurons to steady retinal illumination at different adaptation luminances was studied. The results confirm that in this nucleus the discharge rate is more commonly increased than suppressed by light. Interval histograms indicate that a complex process underlies the di...

journal_title：Neuroscience letters

authors： Groos G,Mason R

更新日期：1978-04-01 00:00:00

abstract：:Periostin has dual roles as a multifunctional cytokine and an extracellular matrix protein that binds to several integrins on a variety of cells. This study evaluated whether the expression and cellular localization of periostin changes in the spinal cord of mice with experimental autoimmune encephalomyelitis (EAE), a...

journal_title：Neuroscience letters

authors： Choi Y,Kim J,Ahn M,Shin T

更新日期：2020-01-10 00:00:00

abstract：:Cortical spreading depression (SD) may produce some symptoms of the aura of classical migraine but it is less probable that it can account for the headache. The aversiveness of SD was examined in unanesthetized rats. In Exp. 1, rats with implanted cortical cannulae were confined in the dark compartment of the step-thr...

journal_title：Neuroscience letters

authors： Koroleva VI,Bures J

更新日期：1993-01-12 00:00:00

abstract：:Dopamine (DA) neurons in the ventral tegmental area and substantia nigra pars compacta were induced to fire in bursts with application of N-methyl-D-aspartate (NMDA, 20 microM) and apamin (100 nM) while recording intracellularly in the rat brain slice. L-Arginine (300 microM), a substrate for nitric oxide (NO) product...

journal_title：Neuroscience letters

authors： Cox BA,Johnson SW

更新日期：1998-10-23 00:00:00

abstract：:Intracellular recordings were used to study the contribution of nicotinic and P2X receptors to synaptic transmission to morphologically identified myenteric neurons of guinea-pig ileum. Hexamethonium (100 microM) abolished fast excitatory synaptic potentials (EPSPs) in all orally projecting neurons, but fast EPSPs in ...

journal_title：Neuroscience letters

authors： Johnson PJ,Shum OR,Thornton PD,Bornstein JC

更新日期：1999-05-14 00:00:00

abstract：:To investigate potential trophic actions of extracellular ATP in human astrocytes, we have examined mitogenic signaling by purinergic receptors in cultures prepared from first trimester rostral central nervous system tissue. We found that ATP and ATPgammaS, a hydrolysis-resistant analog, stimulated DNA synthesis, ther...

journal_title：Neuroscience letters

authors： Neary JT,McCarthy M,Kang Y,Zuniga S

更新日期：1998-02-20 00:00:00

abstract：:Treatment with acamprosate, a compound used for relapse prevention treatment of alcoholism, was recently shown to be associated with increased plasma concentration of beta-endorphin in rats selectively bred for high alcohol preference. The aim of our study was to prove this result in a comparative clinical study with ...

journal_title：Neuroscience letters

authors： Kiefer F,Jahn H,Otte C,Nakovics H,Wiedemann K

更新日期：2006-08-14 00:00:00

abstract：:Cholecystokinin octapeptide (CCK-8) is the most potent endogenous anti-opioid peptide and regulates a variety of physiological processes. In our previous study, we found that exogenous CCK-8 attenuated naloxone-induced withdrawal symptoms, but the possible regulative effects of CCK-8 on the rewarding effects of morphi...

journal_title：Neuroscience letters

authors： Wen D,Cong B,Ma C,Yang S,Yu H,Ni Z,Li S

更新日期：2012-02-21 00:00:00

abstract：:Nerve guide implants approved for human application in the peripheral nervous system generally fail to bridge lesion gaps longer than 2 cm and cannot match the clinical performance of autologous nerve transplants. Since current synthetic implants are simply hollow tubes, we aim to recreate the native microarchitecture...

journal_title：Neuroscience letters

authors： Nichterwitz S,Hoffmann N,Hajosch R,Oberhoffner S,Schlosshauer B

更新日期：2010-10-29 00:00:00

abstract：:The neuritogenic activity of human peripheral nerve myelin proteins in Lewis rats was examined. Experimental allergic neuritis (EAN) was induced by human myelin fraction in all Lewis rats examined. Purified human P2 protein induced mild but definite EAN. None of purified P0 protein, total myelin lipids, gangliosides a...

journal_title：Neuroscience letters

authors： Suzuki M,Kitamura K,Uyemura K,Ogawa Y,Ishihara Y,Matsuyama H

更新日期：1980-10-02 00:00:00

abstract：:Nuclear factor kappa B (NF(kappa)B) transcription factor plays a key role in the expression of many genes involved in the inflammatory process. We used the Freund's Complete Adjuvant (FCA)-induced model of peripheral inflammation to investigate the anti-inflammatory effects of double stranded oligodeoxynucleotides (OD...

journal_title：Neuroscience letters

authors： Igwe OJ

更新日期：2005-06-10 00:00:00

abstract：:Using collision tests of orthodromically and antidromically generated spikes, we studied the axonal pathways, axonal projection levels, and soma location of anterior semicircular canal (AC) nerve-activated vestibulospinal neurons in decerebrate cats. AC nerve-activated vestibulospinal neurons (n=74) were mainly locate...

journal_title：Neuroscience letters

authors： Kitajima N,Sugita-Kitajima A,Bai R,Sasaki M,Sato H,Imagawa M,Kawamoto E,Suzuki M,Uchino Y

更新日期：2006-10-02 00:00:00

abstract：:The input-output relation of a single neuron stands at the basis of every biologically oriented description of the brain. This report shows that the input-output relation of cultured cortical neurons is non-linearly tuned by the input frequency. Increasing the rate of stimulation results in the appearance of ordered t...

journal_title：Neuroscience letters

authors： Tal D,Jacobson E,Lyakhov V,Marom S

更新日期：2001-03-02 00:00:00

abstract：:Although the mechanisms of visual short term memory (VSTM) are extensively investigated in the recent decade, how we compare the representation stored in VSTM to the perceptual input to detect and process the mismatch information remains largely unclear. The current study explored whether there is an ERP component tra...

journal_title：Neuroscience letters

authors： Yin J,Gao Z,Jin X,Ye L,Shen M,Shui R

更新日期：2011-03-10 00:00:00

abstract：:The effect of calcium on the biogenic amine level and distribution in the mouse brain was investigated by a histochemical method using a microscopic photometer (Pl, Nikon). Histochemical fluorescence intensities in the corpus striatum and cortex cerebri regions were significantly increased by the intraventricular admi...

journal_title：Neuroscience letters

authors： Sutoo D,Akiyama K

更新日期：1986-08-15 00:00:00

abstract：:Oxidative stress has been projected as a promising mechanism involved in lead exposure. The lead predisposition catalyzes oxidative reactions and generates reactive oxygen species. The present study was carried out to investigate the effect of oral administration of tannic acid (TA) on behavioral deficit, antioxidativ...

journal_title：Neuroscience letters

authors： Ashafaq M,Tabassum H,Vishnoi S,Salman M,Raisuddin S,Parvez S

更新日期：2016-03-23 00:00:00

abstract：:Recently, we reported that a centrally acting non-narcotic antitussive (cough suppressant drug), tipepidine produces an antidepressant-like effect in the forced swimming test in rats. Because pharmacological properties of tipepidine apparently differ from those of typical antidepressants developed to date, we speculat...

journal_title：Neuroscience letters

authors： Kawaura K,Miki R,Shima E,Honda S,Soeda F,Shirasaki T,Takahama K

更新日期：2010-09-13 00:00:00

abstract：:The mesencephalic trigeminal nucleus contains cell bodies of primary somatic sensory neurons that innervate the head region. The neurons resemble dorsal root ganglion cells but a striking difference is the presence of synaptic boutons in the nucleus. The present report demonstrates with anterograde tracers, the existe...

journal_title：Neuroscience letters

authors： Buisseret-Delmas C,Pinganaud G,Compoint C,Buisseret P

更新日期：1997-07-04 00:00:00

abstract：:To study the neuronal mechanism of a conditioned taste-aversion (CTA) learning in the pond snail Lymnaea stagnalis, we examined the synaptic connection between the neuron 1 medial (N1M) cell and the cerebral giant cell (CGC), the former is an interneuron in central pattern generator for the feeding response and the la...

journal_title：Neuroscience letters

authors： Kojima S,Nanakamura H,Nagayama S,Fujito Y,Ito E

更新日期：1997-07-25 00:00:00

abstract：:The effects of several Ca2+ channel blockers were evaluated on inhibitory junction potential (IJP) evoked in rat colonic circular muscle by electrical field stimulation (EFS). Glass microelecrodes were used to record membrane potential of smooth muscle cells. IJPs were tetrodotoxin-sensitive (1 microM) and disappeared...

journal_title：Neuroscience letters

authors： Borderies JR,Jiménez M,Angel F

更新日期：1996-05-31 00:00:00

abstract：:The in vivo effects of the alpha 2-adrenoceptor idazoxan, rauwolscine and phentolamine on alpha 2-auto/heteroreceptors and 5-HT1A autoreceptors modulating the synthesis of dopa/noradrenaline and 5-HTP/serotonin were assessed in rats, using the accumulation of dopa and 5-HTP after decarboxylase inhibition as a measure ...

journal_title：Neuroscience letters

authors： Lladó J,Esteban S,García-Sevilla JA

更新日期：1996-11-01 00:00:00

abstract：:A paired-pulse stimulus protocol was used to measure angular bundle to dentate gyrus paired-pulse inhibition in rats before and after the occurrence of 36 or 72 seizures elicited from the contralateral CA3 region. The seizures showed progressive lengthening. There was a moderate increase in paired-pulse depression 1 h...

journal_title：Neuroscience letters

authors： Stringer JL,Lothman EW

更新日期：1989-10-23 00:00:00

abstract：:We immunohistochemically investigated the degeneration processes of the nigro-striatal and nigro-amygdaloid pathways and the relationship between the loss of dopaminergic neurons and Lewy bodies (LB) formation in the substantia nigra using 15 autopsied cases of dementia with Lewy bodies (DLB). The number of tyrosine h...

journal_title：Neuroscience letters

authors： Iseki E,Marui W,Yamamoto R,Togo T,Katsuse O,Kato M,Iwatsubo T,Kosaka K,Arai H

更新日期：2005-05-20 00:00:00