Abstract:
:An interaction between heparin and circulating pregnancy-associated plasma protein A (PAPP-A) has been observed. This interaction could be reversed by the addition of the specific heparin antagonist protamine sulphate. In the presence of heparin, crossed immunoelectrophoretic analysis revealed an alteration in the electrophoretic mobility of PAPP-A, while a significant increase (22 to 64 per cent, P less than 0.02) in measured levels of PAPP-A was seen in electroimmunoassays. These findings are discussed in relation to the optimal conditions for the precise measurement of PAPP-A.
journal_name
Placentajournal_title
Placentaauthors
Westergaard JG,Hau J,Teisner B,Grudzinskas JGdoi
10.1016/s0143-4004(83)80013-7subject
Has Abstractpub_date
1983-01-01 00:00:00pages
13-8issue
1eissn
0143-4004issn
1532-3102pii
S0143-4004(83)80013-7journal_volume
4pub_type
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