beta 2-Microglobulin is bound to streptococcal M protein.

abstract：:Six synthetic peptides of the MHC class I molecule corresponding to individual H-2Kb participants in amino acid sequences of domains alpha 1 (peptide 1 and 2) and alpha 2 (peptides 3, 4, 5, 6) were selected. Kb-specific suppressor T cells (Ts) were induced in vivo in mice, then pretreated with a set of peptides and as...

journal_title：Scandinavian journal of immunology

authors： Brondz BD,Anfalova TV,Pavlova LS,Pankratova EV,Kojich AG,Moshnikov SA

更新日期：1993-06-01 00:00:00

abstract：:An antigen-specific T-cell line which transforms into T-lymphoma cells in vitro but apparently not in vivo is described. Membrane markers, tumorigenicity and T-cell receptor (TcR) V alpha and V beta-gene usage of the in vitro transformed T-cell line were analysed to investigate whether the transformation event was pol...

journal_title：Scandinavian journal of immunology

authors： Wegener AM,Holm B,Geisler C,Rubin B

更新日期：1990-05-01 00:00:00

abstract：:In a previous study we observed that after in vitro treatment with indomethacin, lymphocyte response to phytohaemagglutinin (PHA) in primary biliary cirrhosis (PBC) patients was higher than that of controls. We know that indomethacin also inhibits prostanoid production, and thus in the present work we directly measure...

journal_title：Scandinavian journal of immunology

authors： Chiricolo M,Lenzi M,Bianchi F,Franceschi C,Bartolini G,Orlandi M,Tomasi V,Licastro F

更新日期：1989-09-01 00:00:00

abstract：:Chromosomally marked cells from the 7-day intraembryonic mesenchyme were transplanted into 14-day-old irradiated chick embryos. At the age of 6 weeks donor-derived T and B lymphocytes were shown to be present in the thymus, spleen and bone marrow, indicating that cells in the 7-day intraembryonic mesenchyme are capabl...

journal_title：Scandinavian journal of immunology

authors： Lassila O,Eskola J,Toivanen P,Dieterlen-Lièvre F

更新日期：1980-01-01 00:00:00

abstract：:Spleen cells from C3H/HeJ mice fail to develop both proliferative responses and increased polyclonal antibody secretion in the presence of concentrations of the B-cell mitogen lipopolysaccharide that are optimal for the induction of B-cell responses in conventional strains. This unresponsiveness is selective for lipop...

journal_title：Scandinavian journal of immunology

authors： Coutinho A,Gronowicz E,Sultzer BM

更新日期：1975-01-01 00:00:00

abstract：:Administration of D-penicillamine (50 mg/kg/day orally) to rats with adjuvant arthritis for up to 42 days significantly modified the incorporation of 3H-thymidine (3H-TdR) in concanavalin A (Con A)-stimulated lymph node cells. Treatment with D-penicillamine abolished the ability of macrophages from arthritic rats to i...

journal_title：Scandinavian journal of immunology

authors： Binderup L,Bramm E,Arrigoni-Martelli E

更新日期：1980-01-01 00:00:00

abstract：:A twofold increase in lymphocyte adherence to rat microvascular endothelial cells (EC) was achieved by incubating EC for 4 h with IL-1 alpha or dibutyryl-cAMP (stimulators of protein kinase A, PKA) and PMA (stimulator of protein kinase C, PKC). Monoclonal antibodies anti-CD11a, anti-CD18 (LFA-1) and anti-CD49d (VLA-4 ...

journal_title：Scandinavian journal of immunology

authors： Turunen JP,Ustinov J,Renkonen R

更新日期：1993-03-01 00:00:00

abstract：:Saliva was collected from 57 infants aged 6 weeks to 2.5 years and the molecular form of IgA was studied by centrifugation on sucrose density gradients. Two distinct populations were identified. Seventy-two per cent of the children had secretory IgA in their salivary secretions, while 28% had a molecular form correspo...

journal_title：Scandinavian journal of immunology

authors： Cripps AW,Gleeson M,Clancy RL

更新日期：1989-03-01 00:00:00

abstract：:Antigen-specific lymphocyte hybridomas have been produced by a simple in vitro immunization procedure. Non-immune spleen cells have been activated in vitro, and the B-cell blasts have subsequently been used for somatic cell hybridization. Hybrids secreting monoclonal antibodies to human myoglobin, pig insulin, and ben...

journal_title：Scandinavian journal of immunology

authors： Borrebaeck CA

更新日期：1983-07-01 00:00:00

abstract：:Persistent humoral immunity depends on the follicular B cell response and on the generation of somatically mutated high-affinity plasma cells and memory B cells. Upon activation by an antigen, cognately activated follicular B cells and follicular T helper (TFH ) cells initiate germinal centre (GC) reaction during whic...

journal_title：Scandinavian journal of immunology

authors： Nera KP,Kyläniemi MK,Lassila O

更新日期：2015-09-01 00:00:00

abstract：:Systemic autoimmune diseases are characterized by the development of antinuclear autoantibodies. In order to understand the immunologic events leading to the development of such antibodies, knowledge of mechanisms of immune tolerance to nuclear antigens is required. By utilizing adoptive T-cell transfer strategies wit...

journal_title：Scandinavian journal of immunology

authors： Nakken B,Davis KE,Pan ZJ,Bachmann M,Farris AD

更新日期：2003-11-01 00:00:00

abstract：:Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo-embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occurrence of the arrh...

journal_title：Scandinavian journal of immunology

authors： Lappegård KT,Hovland A,Pop GA,Mollnes TE

更新日期：2013-08-01 00:00:00

abstract：:The aim of this study was to describe the kinetics of the cytokine release and the expression of activation markers on lymphocytes after stimulation of peripheral blood mononuclear cells (PBMC) with whole killed Streptococcus pneumoniae. The cytokine release and the expression of CD25 and HLA-DR on T cells, and CD69 o...

journal_title：Scandinavian journal of immunology

authors： Arvå E,Andersson B

更新日期：1999-03-01 00:00:00

abstract：:In these case reports, we investigated pandemic influenza 2009 vaccination of primary hypogammaglobulinaemic patients. Three combined variable immunodeficiency (CVID) patients and one X-linked agammaglobulinaemia (XLA) patient were vaccinated with the pandemic vaccine A/California/7/2009 (H1N1)-like split virus (X179a...

journal_title：Scandinavian journal of immunology

authors： Pedersen G,Halstensen A,Sjursen H,Naess A,Kristoffersen EK,Cox RJ

更新日期：2011-08-01 00:00:00

abstract：:The tumour necrosis factor-α (TNF-α) promoter -308 A/G polymorphism plays an important role in the aetiology of systemic lupus erythematosus (SLE). Several studies have estimated the association between TNF-α -308 A/G and SLE risk. However, results were inconsistent. A case-control study was carried out to explore the...

journal_title：Scandinavian journal of immunology

authors： Yang ZC,Xu F,Tang M,Xiong X

更新日期：2017-03-01 00:00:00

abstract：:Anti-inflammation strategy is one of the proposed therapeutic approaches to hepatic fibrosis. T helper (Th) 17 cells, which play a detrimental role in experimental murine models of inflammatory diseases, have been demonstrated to participate in the pathogenesis of liver damage. The inhibitory effect of halofuginone (H...

journal_title：Scandinavian journal of immunology

authors： Liang J,Zhang B,Shen RW,Liu JB,Gao MH,Geng X,Li Y,Li YY,Zhang W

更新日期：2014-03-01 00:00:00

abstract：:The identification of a herd of goats with tuberculosis let us test a new treatment regimen against latent tuberculosis infection (LTBI). Using large animal experimental models allows a better approach to understanding human tuberculosis according to immunopathological parameters. Based on an initial study showing a c...

journal_title：Scandinavian journal of immunology

authors： Domingo M,Gil O,Serrano E,Guirado E,Nofrarias M,Grassa M,Cáceres N,Pérez B,Vilaplana C,Cardona PJ

更新日期：2009-06-01 00:00:00

abstract：:Cellular immune response and delayed-type hypersensitivity reactions are considered to play a major role in the immunopathogenesis of pulmonary tuberculosis (PTB). But the exact mechanism is still to be clarified. Th1 cells are mainly involved in cellular immune responses in PTB and provide a normal healing process wi...

journal_title：Scandinavian journal of immunology

authors： Aktas E,Ciftci F,Bilgic S,Sezer O,Bozkanat E,Deniz O,Citici U,Deniz G

更新日期：2009-09-01 00:00:00

abstract：:Mouse macrophages were cultured on chemically modified plastic dishes. On dishes covered with immobilized glycans, the macrophages were stimulated as judged by increased 14C-glucosamine incorporation, increased cytostatic and cytolytic capacities and by morphology as seen by scanning electron microscopy. The correspon...

journal_title：Scandinavian journal of immunology

authors： Bøgwald J,Gouda I,Hoffman J,Larm O,Larsson R,Seljelid R

更新日期：1984-10-01 00:00:00

abstract：:The murine primed lymphocyte typing (mPLT) assay, based on the sequential reactivation of specific immunocompetent, alloantigen-reactive T blast cells in secondary mixed leucocyte culture (MLC), has been utilized to define the class II I-EC-subregion-associated lymphocyte-stimulating (LS) determinants of the major his...

journal_title：Scandinavian journal of immunology

authors： Peck AB

更新日期：1980-01-01 00:00:00

abstract：:Factor B is an essential component of the complement cascade which forms the C3 and C5 convertase of the alternative pathway. Factor B cleavage products also function as cofactors in antibody-independent monocyte-mediated cytotoxicity, macrophage spreading, plasminogen activation and proliferation of B lymphocytes. Se...

journal_title：Scandinavian journal of immunology

authors： Pekna M,Hietala MA,Landin A,Nilsson AK,Lagerberg C,Betsholtz C,Pekny M

更新日期：1998-04-01 00:00:00

abstract：:Screening for B-cell-specific antibodies in unabsorbed pregnancy sera preselected for weak reactivity in regular HLA-A, -B, and -C screening yielded a relatively high proportion (35/81) of B-cell-specific antibodies. Most B-cell-specific antibodies react broadly, showing inclusion phenomena suggesting 'cross-reactivit...

journal_title：Scandinavian journal of immunology

authors： Albert ED,Andreas A,McNicholas A,Scholtz S,Kuntz B

更新日期：1977-01-01 00:00:00

abstract：:MTB12 protein, also called CFP-2, is a major and early secreted component of Mycobacterium tuberculosis. However, its role during mycobacterial infection has been poorly characterized. In this study, we purified the native MTB12 protein and investigated the profile of MTB12-induced cytokines [interferon (IFN)-gamma, t...

journal_title：Scandinavian journal of immunology

authors： Lee JS,Son JW,Jung SB,Kwon YM,Yang CS,Oh JH,Song CH,Kim HJ,Park JK,Paik TH,Jo EK

更新日期：2006-08-01 00:00:00

abstract：:The possible immunological relationship between the pattern of Th1/Th2 cytokine production and tuberculin reactivity was assessed in patients with active Mycobacterium tuberculosis infection. The production of the intracellular cytokines interferon (IFN)-gamma and interleukin-4 (IL-4) was measured in CD4(+) and CD8(+)...

journal_title：Scandinavian journal of immunology

authors： Boras Z,Juretić A,Gagro A,Pavelić Lj

更新日期：2007-03-01 00:00:00

abstract：:Immature monocytes residing in the spleens of newborn mice less than 6-7 days of age are known to suppress T-dependent and T-independent immune responses in vitro and in vivo. Suppression is mediated in part through products secreted by the newborn monocytes. In the present study, we have identified 3 monokines secret...

journal_title：Scandinavian journal of immunology

authors： Jadus MR,Peck AB

更新日期：1986-01-01 00:00:00

abstract：:To delineate accurately the IgG subclass distribution of thyroid auto-antibodies, sera from nine patients with Hashimoto's thyroiditis were fractionated into IgG subclasses by complete depletion of the other IgG subclasses on affinity columns. All IgG subclass fractions contained thyroglobulin and microsomal (or thyro...

journal_title：Scandinavian journal of immunology

authors： Weetman AP,Black CM,Cohen SB,Tomlinson R,Banga JP,Reimer CB

更新日期：1989-07-01 00:00:00

abstract：:γδ T cells are characterized by recognizing conserved endogenous and stress-induced antigens without antigen presentation. It has been show that γδ T cells play an important role in anti-tumour/microbe responses, but their function in autoimmune diseases is yet not clear. Here, we reported the quantity and phenotype o...

journal_title：Scandinavian journal of immunology

authors： Wang L,Kang N,Zhou J,Guo Y,Zhang X,Cui L,Ba D,He W

更新日期：2012-07-01 00:00:00

abstract：:Mycobacteria preferentially reside in resident macrophages whereas activated macrophages are presumed to eliminate the bacteria effectively. The aim of the present study was to determine the antibacterial activities of resident and activated murine peritoneal macrophages against Mycobacterium fortuitum and the intrace...

journal_title：Scandinavian journal of immunology

authors： Nibbering PH,Yoshida SI,van den Barselaar MT,van Furth R

更新日期：1994-08-01 00:00:00

abstract：:This paper describes a technique utilizing rosette formation with sheep red blood cells as a human T lymphocyte marker, and separation of T cells by rosette sedimentation. ...

journal_title：Scandinavian journal of immunology

authors： Jondal M

更新日期：1976-06-01 00:00:00

abstract：:With the aim of producing large quantities of mRNA-transfected monocyte-derived dendritic cells (DCs) to be used as cancer vaccines, a new clinical grade procedure has been developed. Peripheral blood mononuclear cells (PBMCs) obtained by leukapheresis were enriched for monocytes by immunomagnetic depletion of CD19+ B...

journal_title：Scandinavian journal of immunology

authors： Mu LJ,Gaudernack G,Saebøe-Larssen S,Hammerstad H,Tierens A,Kvalheim G

更新日期：2003-11-01 00:00:00