Abstract：
:The effects of lindane on alpha-aminoisobutyric acid and uridine uptake were studied in the rat line C-6 of glial origin. Different levels of modifications could be distinguished by use of 2 modes of investigation. One study, carried out within minutes of contact with lindane, has shown that the inhibition of alpha-aminoisobutyric acid and uridine uptake was rapid and immediately reversible. The other study, carried out after several hours of treatment followed by a 15-min triple washing, has allowed to attribute the non-reversible decrease in uridine uptake induced by a 20-h treatment to an inhibition of protein synthesis, and the increase in alpha-aminoisobutyric acid uptake to the derepression of synthesis of transport proteins.
journal_name
Toxicologyjournal_title
Toxicologyauthors
Roux F,Treich I,Fournier Edoi
10.1016/0300-483x(80)90103-1subject
Has Abstractpub_date
1980-01-01 00:00:00pages
261-4issue
2eissn
0300-483Xissn
1879-3185pii
0300-483X(80)90103-1journal_volume
17pub_type
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