Abstract：
:Human female lymphocytes were exposed to X-rays in vitro at 7 different doses between 40-280 R. In 830 metaphases chromosome analyses were carried out with either conventional staining or G-banding, respectively. 486 breakpoints are non-randomly distributed between chromosomes and chromosome arms. An excess of lesions was present in chromosomes 1 and 5 or in 1p. 85% of the lesions were located in G-negative bands (pale G-bands). 29% of all lesions appeared in either the last terminal pale band (21%) or in the centromere region (8%). With regard to an application of G-banding for a biological dose-estimation, the dose-response relations of dic and ace were analysed. Although G-banding enables detailed analysis of the whole karyotype it cannot be recommended for cytogenetic routine analyses in medical radioprotection monitoring, without suitable automated scoring techniques. Dose estimations based on the frequency of dic and carried out with conventional staining cannot be essentially improved at present with banding. Nevertheless, by banding criteria for a correct evaluation of other aberration types, e.g. ace, can be provided. This is a prerequisite for the calculation of representative dose-effect curves.
journal_name
Radiat Environ Biophysjournal_title
Radiation and environmental biophysicsauthors
Bauchinger M,Götz Gdoi
10.1007/BF01340573subject
Has Abstractpub_date
1979-01-01 00:00:00pages
355-66issue
4eissn
0301-634Xissn
1432-2099journal_volume
16pub_type
杂志文章abstract：:The results of a study in which groups of sheep were given single oral administrations of 14C, 3H and 35S and then slaughtered over a period of 1 year are reported. The experimental data were used to investigate the potential of metabolically based models for describing the transfer of the three radionuclides to sheep...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s004110050078
更新日期：1998-02-01 00:00:00
abstract：:The potential of naturally occurring antioxidants to reduce the cellular oxidative damage induced by ionizing radiation has been studied for more than a decade for their pharmacological application during cancer treatment. It is already known that radioprotective efficacy of phytochemicals might influence various end ...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-014-0551-8
更新日期：2014-11-01 00:00:00
abstract：:One of the main purposes leading botanists to investigate the effects of ionizing radiations is to understand plant behaviour in space, where vegetal systems play an important role for nourishment, psychological support and functioning of life support systems. Ground-based experiments have been performed with particle...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章,评审
doi：10.1007/s00411-010-0343-8
更新日期：2011-03-01 00:00:00
abstract：:To explore the expression level and the role of peroxisome proliferator-activated receptor gamma (PPAR-γ) in radiation-induced heart injury in a rat model, thirty-two Sprague-Dawley rats were divided into three groups (the control group, the 15-Gy irradiation group and the 18-Gy irradiation group). Experimental animal...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-011-0390-9
更新日期：2012-03-01 00:00:00
abstract：:Non-linear mechanical response of viscoelastic strain responding media to high amplitude stress-strain is examined from a phenomenological point of view and found to lead to results compatible with empirical observations of high intensity ultrasound irradiation of brain, liver, and eye lens tissues. The proposed hyste...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01324230
更新日期：1981-01-01 00:00:00
abstract：:In this work, direct DNA damage induced by low-energy electrons (<5 keV) is simulated using Monte Carlo methods, and the resulting yield of various strand breaks and base damages in cellular environment is presented. The simulation is based on a new inelastic cross section for the production of electron track structur...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-009-0262-8
更新日期：2010-03-01 00:00:00
abstract：:Four different thiol reagents: p-chloromercuribenzoic acid (pCMB), mercuric chloride (HgCl2), N-ethylmaleimide (NEM), and 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) were employed as agents modifying the transport of a hydrophilic and hydrophobic non-electrolyte spin labels: 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-o...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01323760
更新日期：1983-01-01 00:00:00
abstract：:The root apex cells of Pisum sativum were irradiated in an U-240 isochronous cyclotron at the Institute for Nuclear Research of the Ukrainian National Academy of Sciences, Kyiv. Several types of micronuclei, differing in structural peculiarities, were observed in the 84 h following exposure to beams of accelerated 1H,...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01275215
更新日期：1995-06-01 00:00:00
abstract：:The potential of proton microchannel radiotherapy to reduce radiation effects in the healthy tissue but to keep tumor control the same as in conventional proton therapy is further elucidated. The microchannels spread on their way to the tumor tissue resulting in different fractions of the healthy tissue covered with d...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-015-0600-y
更新日期：2015-08-01 00:00:00
abstract：:Growing hair follicles with their rapid cell proliferation would be expected to be sensitive organs to cytotoxic agents such as radiation. Various abnormalities in the hair and hair follicles have been reported in the past. Changes in the number of cells in the newly forming hair cortex have been shown in the mouse to...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF02434035
更新日期：1996-05-01 00:00:00
abstract：:Ionizing radiation can produce adverse biological effects in astronauts during space travel. Of particular concern are the types of radiation from highly energetic, heavy, charged particles known as HZE particles. The aims of our studies are to characterize HZE particle radiation induced biological effects and evaluat...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-006-0089-5
更新日期：2007-06-01 00:00:00
abstract：:Microcalorimetric experiments on growth and maintenance metabolism of Saccharomyces strains ranging from haploid to hexaploid are described. During growth, the mean dry weight, the mean volume and the maximum heat flux of the cells are nearly linear functions of ploidy. These parameters are correlated with the cell co...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01323624
更新日期：1976-03-30 00:00:00
abstract：:Frequently knowledge of elemental content of human organs and tissues is required for a variety of applications. These can include brachytherapy and radiotherapy planning, radiation dosimetry and radiation protection. Revised reference values of chemical element mass fractions in normal and cancerous prostate tissues ...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-020-00884-5
更新日期：2021-01-02 00:00:00
abstract：:Microcalorimetry, in combination with conventional methods for determining metabolic activity, opens the possibility to study the efficiency with which ATP, produced as a result of metabolic activity, is utilized by the cell for energy-requiring synthetic reactions. Using commercial baker's yeast as a test organism an...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01323416
更新日期：1975-12-04 00:00:00
abstract：:Heavy charged particle therapy, started at research institutes three decades ago, is now on the verge of entering a clinical phase. This phase has resulted from the evolution and development of various beam delivery systems and techniques with existing research accelerators and with newly built accelerators. For the f...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章,评审
doi：10.1007/BF01214829
更新日期：1992-01-01 00:00:00
abstract：:The sulphur-containing radioprotectors mercaptoethylamine (MEA), aminoethylisothiourea (AET), 2- aminothiazoline , 4-oxo-2- aminothiazoline , and S-S-3- oxapentane -1,5- diisothiourea , and the radioprotective biogenic amines serotonin, histamine, and dopamine, caused the elevation of cAMP content and intensified the ...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01213732
更新日期：1984-01-01 00:00:00
abstract：:Indoor exposure to natural radon is a factor that influences lung cancer risk worldwide. The present study includes a meta-analysis of epidemiological data on the relationship between lung cancer and indoor radon. Altogether, 31 case-control studies with 20,703 cases, 34,518 controls and 140 individual odds ratio (OR)...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章,meta分析
doi：10.1007/s00411-018-0770-5
更新日期：2019-03-01 00:00:00
abstract：:Mass attenuation coefficient, μm, atomic cross-section, σi, electronic cross-section, σe, effective atomic number, Zeff and effective electron density, Nel, were determined experimentally and theoretically for some vitamins (retinol, beta-carotene, thiamine, riboflavin, niacinamide, pantothenic acid, pyridoxine, bioti...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-012-0427-8
更新日期：2012-11-01 00:00:00
abstract：:The main aim of this study was to investigate the dosimetric characteristics of the INTRABEAM ® system in the presence of air gaps between the surface of applicators (APs) and tumor bed. Additionally, the effect of tissue heterogeneities was another focus. Investigating the dosimetric characteristics of the INTRABEAM®...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-020-00835-0
更新日期：2020-05-01 00:00:00
abstract：:Stem cells surviving radiation injury may carry defects which contribute to long-term effects. The ratio of 125-iododeoxyuridine (IUdR) uptake into spleens of lethally irradiated recipient mice between day 3 and day 5 after cell transfusion revealed reduced proliferative ability (PF) of spleen seeding cells in paralle...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01211733
更新日期：1986-01-01 00:00:00
abstract：:It is shown by UV absorption and absolute fluorescence spectroscopy of solutions containing both DNA and quinacrine that the components experience mutual radio-protection due to scavenging of water radicals. From measurements at different ionic strengths it is inferred that quinacrine bound to DNA is more efficiently ...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF02339804
更新日期：1975-06-13 00:00:00
abstract：:The rate constants for the photodynamic inactivation of hen egg-white lysozyme at different temperatures were studied. Arrhenius plots of the methylene blue sensitized photo-inactivation of lysozyme gave an experimental activation energy of 7.5 kcal/mol. The rate constants for the photodynamic inactivation of lysozyme...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01326898
更新日期：1979-02-23 00:00:00
abstract：:Radiation-related risks of cancer can be transported from one population to another population at risk, for the purpose of calculating lifetime risks from radiation exposure. Transfer via excess relative risks (ERR) or excess absolute risks (EAR) or a mixture of both (i.e., from the life span study (LSS) of Japanese a...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-012-0441-x
更新日期：2013-03-01 00:00:00
abstract：:To investigate whether residual radiation damage in hematopoietic tissue is measurable in situ by a change in cell turnover, the retention of the thymidine analogue 5-(125-I)iodo-2'-deoxyuridine (125-IUdR) following incorporation into DNA of cells in bone marrow and spleen of mice was measured 35 days after 0-500 rad ...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01325468
更新日期：1982-01-01 00:00:00
abstract：:Radiocaesium absorption and retention in reindeer (Rangifer tarandus) calves was compared in groups fed diets containing different proportions of lichen and concentrates, and different chemical forms of radiocaesium ((134)CsCl in solution or fallout from the Chernobyl accident). Daily intakes of fallout radiocaesium w...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-004-0257-4
更新日期：2004-12-01 00:00:00
abstract：:Simple, ellipsoidal geometries have long been the standard for estimating radiation dose rates in non-human biota (NHB). With the introduction of a regulatory protection standard that emphasizes protection of NHB as its own end point, there has been interest in improved models for the calculation of dose rates in NHB....
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-014-0546-5
更新日期：2014-08-01 00:00:00
abstract：:Activity concentrations of the selected radionuclides (40)K, (226)Ra and (232)Th were measured in surface soil samples collected from 38 cities in the southwest region of Nigeria by means of gamma spectroscopy with a high-purity germanium detector. Measured activity concentration values of (40)K varied from 34.9 +/- 4...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-009-0225-0
更新日期：2009-08-01 00:00:00
abstract：:The work reported here was originally motivated by a discussion of Monte Carlo computer codes for electron transport in water given in Report No. 130 by the National Council on Radiation Protection and Measurements (NCRP). It was pointed out (correctly) that a published depth-dose distribution calculated by the Oak Ri...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-003-0201-z
更新日期：2003-10-01 00:00:00
abstract：:In this study, temporal variations of indoor radon concentrations in Bulgaria were investigated. The radon concentrations were measured by nuclear track detectors as part of the Bulgarian National Survey, performed in the dwellings of 28 regional districts. The detectors were exposed through a year in two consecutive ...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/s00411-019-00789-y
更新日期：2019-08-01 00:00:00
abstract：:This study was undertaken to investigate the mechanism of chemical radiosensitization by halogenated bases incorporated into DNA. Radiation-induced base and sugar-phosphate backbone damage to 5-bromouridine-5'-monophosphate (5-BrUMP) was monitored using a flow system connected in series with a recording spectrophotome...
journal_title：Radiation and environmental biophysics
pub_type： 杂志文章
doi：10.1007/BF01211508
更新日期：1992-01-01 00:00:00
