Abstract：
:In order to compare the functional state of the anterior pituitary of spontaneously hypertensive rats (SHR) with that of nonmotensive Wistar Kyoto rats (WKR), the anterior pituitary was examined by morphometry and autoradiography at the level of electron microscopy. The relative number and the relative volume of thyrotrophs in the anterior pituitary were significantly greater in SHR compared with age-matched WKR at 0, 7, 30-33 days and 10 months of age, while the relative number of somatotrophs in SHR was significantly smaller at 1 and 10 months of age. Electron microscope autoradiographic analysis of uptake of 3H-lysine by thyrotrophs of both strains at the age of approximately one month showed that 3H-lysine was incorporated into protein and transported finally to secretory granules which migrated to near the cell membrane to be discharged. Silver grains were significantly more numerous over the thyrotrophs of SHR than over those of WKR at 30 min, 1 h, and 4 h after the injection of 3H-lysine. The present study has ascertained morphologically than a congenital hypersynthesis of TSH by the anterior pituitary occurs in SHR.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Fujiwara Tdoi
10.1007/BF00237005subject
Has Abstractpub_date
1979-10-01 00:00:00pages
467-77issue
3eissn
0302-766Xissn
1432-0878journal_volume
201pub_type
杂志文章abstract：:The globiferous pedicellariae of Psammechinus miliaris are described. Two fixation methods giving minimal distortion and rapid tissue hardening were adapted for soft tissue preparation for scanning electron microscopy. The pedicellarial valves are covered by a microvillous epithelium. The outer valve epithelial microv...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220184
更新日期：1975-10-13 00:00:00
abstract：:Electron-microscopic autoradiography of rat neurohypophyses treated with [3H] clonidine, an alpha 2-agonist, showed that binding apparently occurred preferentially at the neurosecretory endings and blood vessels rather than on the pituicytes. Since it is known that clonidine has a high affinity for plasma proteins, th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219223
更新日期：1986-01-01 00:00:00
abstract：:alpha-Smooth muscle (alpha SM) actin of endothermic vertebrates is selectively recognized by the monoclonal antibody anti-alpha SM-1. Immunoreactivity to this antibody has been shown to be localized in the NH2-terminal sequence Ac-EEED (Chaponnier et al. 1994). Among terrestrial ectothermic vertebrates, two amphibian ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00417867
更新日期：1995-09-01 00:00:00
abstract：:The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the principal molecular units for fast excitatory synaptic transmission in the central nervous system. The glutamate-mediated transmission efficiency of synaptic AMPA receptors is influenced by their subunit composition (GluR-A to GluR-D...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-006-0275-4
更新日期：2006-11-01 00:00:00
abstract：:The dental follicle is an ectomesenchymal tissue that surrounds developing tooth germ and that contains osteoblastic-lineage-committed stem/progenitor cells. We examined the osteogenic potential of human dental follicle cells (hDFC) by microarray analysis. We first compared the characteristics of hDFC with those of hu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1477-6
更新日期：2012-11-01 00:00:00
abstract：:Experimental autoimmune orchitis (EAO) in the rat is the primary chronic animal model for the investigation of one of the main causes of male infertility, viz., testicular inflammation. Dendritic cells (DC) are potent antigen-presenting cells that play a fundamental role in autoimmune disease. We investigated the numb...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0129-5
更新日期：2006-05-01 00:00:00
abstract：:Iron loading of hepatocytes was followed through the stages (1-7) of metamorphosis in lamprey (Petromyzon marinus L.) using light- and electron-microscopic histochemistry. Iron is present in ferric and ferrous forms in the hepatocytes of larval lampreys in levels that can only be detected in the electron microscope. D...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217405
更新日期：1983-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-020-03327-1
更新日期：2021-01-06 00:00:00
abstract：:In the developing mammalian nervous system, common progenitors integrate both cell extrinsic and intrinsic regulatory programs to produce distinct neuronal and glial cell types as development proceeds. This spatiotemporal restriction of neural progenitor differentiation is enforced, in part, by the dynamic reorganizat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-2011-9
更新日期：2015-01-01 00:00:00
abstract：:Cells binding anti-bovine TASH beta serum were found exclusively in the rostral lobe of the adenohypophysis of the drake using the peroxidase-antiperoxidase complex unlabelled antibody method. The specificity of the binding of the anti-serum to TSH cells was established by relating the morphology and relative abundanc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234834
更新日期：1979-04-30 00:00:00
abstract：:The fine structure and primary sensory projections of sensilla located in the labial-palp pit organ of the cotton bollworm Helicoverpa armigera (Insecta, Lepidoptera) are investigated by scanning electron and transmission electron microscopy combined with confocal laser scanning microscopy. The pit organ located on th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1657-z
更新日期：2013-09-01 00:00:00
abstract：:Neurons displaying FMRFamide(Phe - Met - Arg - Phe - NH2)-like immunoreactivity have recently been implicated in neural plasticity in salmon. We now extend these findings by describing the extent of the FMRF-like immunoreactive (FMRF-IR) system in the brain, retina and olfactory system of sockeye salmon parr using the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00313518
更新日期：1990-09-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00319144
更新日期：1995-10-01 00:00:00
abstract：:The development of the egg envelope and its incorporation into the larval cuticle of the polychaete Phragmatopoma lapidosa, was studied by correlative scanning and transmission electron microscopy. The mature egg possesses an envelope composed of five zones including an outer granular zone formed by the tips of the eg...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00225530
更新日期：1978-01-17 00:00:00
abstract：:During tooth development, the inner and outer enamel epithelia fuse by mitotic activity to produce a bilayered epithelial sheath termed Hertwig's epithelial root sheath (HERS). The epithelial rests of Malassez (ERM) are the developmental residues of HERS and remain in the adult periodontal ligament (PDL). Although the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-1076-3
更新日期：2010-12-01 00:00:00
abstract：:The brood pouch of the male pipefish (Syngnathus schlegeli) is a ventral organ located on the tail, with the anterior region closely associated with the genital pore. The embryos in the pouch are attached to highly vascularized placenta-like tissue which seals the pouch folds from inside during incubation. The epithel...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051220
更新日期：1999-01-01 00:00:00
abstract：:Membrane-coating granules of the epithelium of the hamster cheek pouch displayed a lamellated internal structure consisting of alternating thick and thin electron dense bands separated by translucent bands of equal width. The repeat distance of the contents was 8.5 nm +/- sd. 0.7 nm and the thickness of the major elec...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224374
更新日期：1978-02-24 00:00:00
abstract：:Central projections of the nervus terminalis (n.t.) in the goldfish were investigated using cobalt- and horseradish peroxidase-tracing techniques. Single n.t. fibers were identified after unilateral application of cobalt chloride-lysine to the rostral olfactory bulb. The central course and branching patterns of indivi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218095
更新日期：1986-01-01 00:00:00
abstract：:Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors. It then attempts to outline the gene...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-006-0265-6
更新日期：2006-11-01 00:00:00
abstract：:The present review describes several lines of recent evidence providing new insights into the basic principles and mechanisms of axon projection from the olfactory epithelium to the olfactory bulb. Olfactory sensory neurons are classified into approximately 1000 subtypes according to the expression of specific odorant...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410050953
更新日期：1997-11-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03201-0
更新日期：2020-09-01 00:00:00
abstract：:Neural stem cells (NSCs) are a subtype of tissue-specific progenitor cells capable of extended self-renewal and the ability to generate all major cell types of nervous tissue, such as neurons, astroglia and oligodendroglial cells. Recent studies suggest that salient patterning in anterior-posterior and dorsal-ventral ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-004-0923-5
更新日期：2004-10-01 00:00:00
abstract：:Mole rat bone marrow cells and peritoneal eosinophils are used to study granule morphological maturation by quantitative microscopy. The bulk eosinophil granule content is pre-stored in unique granular structures known as crystalloid or secondary granules. Mole rat eosinophil granules exhibit the basic structure of an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2189-5
更新日期：2015-10-01 00:00:00
abstract：:The reduced-folate carrier (Rfc-1), previously also called methotrexate carrier-1 (MTX-1), was recently identified as accounting for approximately 30% of the methotrexate (Mtx) uptake into rat kidney slices. The localization of the carrier and its contribution to secretory or reabsorptive flux of the drug was therefor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1092-x
更新日期：2005-06-01 00:00:00
abstract：:Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2593-0
更新日期：2017-07-01 00:00:00
abstract：:Cyclooxygenase-2 (COX-2) is a recently discovered isoform of cyclooxygenase that is inducible by various types of inflammatory stimuli. Although this enzyme is considered to play a major role in inflammation processes by catalyzing the production of prostaglandins, the precise location, distribution, and regulation of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000296
更新日期：2001-02-01 00:00:00
abstract：:Whether environmental exposure to bisphenol A (BPA) may induce reproductive disorders is still controversial but certain studies have reported that BPA may cause meiotic abnormalities in C. elegans and female mice. However, little is known about the effect of BPA on meiosis in adult males. To determine whether BPA exp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1723-6
更新日期：2014-01-01 00:00:00
abstract：:Complex intracellular inclusion bodies of the Biondi type were observed in the choroidal epithelium (choroid plexus of the lateral ventricle) of a 43-year-old male chimpanzee. The specific components of these inclusions are bundles of filaments 8-15 nm in diameter, which are associated with lipid droplets and a wide v...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217876
更新日期：1984-01-01 00:00:00
abstract：:The distribution of the molluscan cardioexcitatory tetrapeptide FMRFamide (Phe-Met-Arg-Phe-NH2) in the brain of the cloudy dogfish, Scyliorhinus torazame, was examined by immunocytochemistry. FMRFamide-like immunoreactivity was demonstrated to occur extensively in various regions of the dogfish brain, except for the c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00398072
更新日期：1991-08-01 00:00:00
abstract：:The submandibular gland (SMG) is a tissue that can be regenerated in a tissue injury model and that has adult stem cells capable of self-renewal and differentiation into functional cells. We have analyzed the localization of label-retaining cells (LRCs), which are putative progenitor cells, by using the BrdU-labeling ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0667-8
更新日期：2008-10-01 00:00:00
