Gene frequency analysis of chromosomal initiation sites in Bacillus subtilis after ultraviolet light or x-ray exposure.

Abstract:

:Bacillus subtilis was exposed to ultraviolet light (UV) or X rays, and gene frequency analysis was used to study the location of initiation sites of postirradiation deoxyribonucleic acid (DNA) synthesis. It was found that DNA synthesis resumes primarily from the origin after UV exposure. With X irradiation, the origin is not selectively replicated. Elevated origin-to-terminal marker ratios observed after UV exposure of exponentially growing cells were interpreted as evidence for selective UV resistance of the replicative origin region of the bacterial chromosome.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Billen D,Hellerman G,Carreira L

doi

10.1128/JB.109.1.379-384.1972

subject

Has Abstract

pub_date

1972-01-01 00:00:00

pages

379-84

issue

1

eissn

0021-9193

issn

1098-5530

journal_volume

109

pub_type

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