Abstract:
:Eukaryotic structural gene mutations occurring spontaneously in a mouse myeloma cell line offer the opportunity to study somatic mutation in animal cells at the molecular level. Studies on the myeloma protein and on mRNA have enabled us to characterise four such mutants representing four different mutation mechanisms. The results may have some bearing on the origin of antibody diversity.
journal_name
Naturejournal_title
Natureauthors
Adetugbo K,Milstein C,Secher DSdoi
10.1038/265299a0subject
Has Abstractpub_date
1977-01-27 00:00:00pages
299-304issue
5592eissn
0028-0836issn
1476-4687journal_volume
265pub_type
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