Abstract:
:The goal of the present investigation was to study whether periodic use of fluoride-gel treatments resulted in an increased prevalence of dental fluorosis. 269 children, from 14 to 16 years of age, who had received semi-annual or quarterly fluoride-gel treatments were examined for possible fluoride-induced enamel changes. Further, in order to determine the amount of fluoride retained during the gel treatment, the expectorate was analyzed in 18 younger children presently participating in the prophylaxis program. It was found that the retention of fluoride averaged 7.3 mg per treatment (up to 0.5 mg fluoride per kg body weight). An increased prevalence of dental fluorosis was not observed, even after up to five yearly treatments were given during tooth formation periods. The background prevalence of dental fluorosis in a low-fluoride area in Denmark is described.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Larsen MJ,Kirkegård E,Fejerskov O,Poulsen Sdoi
10.1177/00220345850640081101subject
Has Abstractpub_date
1985-08-01 00:00:00pages
1076-9issue
8eissn
0022-0345issn
1544-0591journal_volume
64pub_type
杂志文章abstract::Phosphorylated extracellular matrix proteins, including matrix extracellular phosphoprotein (MEPE), are involved in the formation and mineralization of dental tissues. In this study, we evaluated the potential of Dentonin, a synthetic peptide derived from MEPE, to promote the formation of reparative dentin. Agarose be...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600818
更新日期:2007-08-01 00:00:00
abstract::Cytotoxicity of fine cut amalgam was persistent until 24 hours after trituration in vitro, whereas cytotoxicity of spherical amalgam diminished more quickly. Increasing mercury content in spherical amalgam increased cytotoxicity. Possible reactions for the diminution of cytotoxicity of amalgams with time are discussed...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Previous studies show that both activin and Bmp4 act as crucial mesenchymal odontogenic signals during early tooth development. Remarkably, mice lacking activin-βA ( Inhba-/-) and mice with neural crest-specific inactivation of Bmp4 ( Bmp4ncko/ncko) both exhibit bud-stage developmental arrest of the mandibular molar t...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517713710
更新日期:2017-09-01 00:00:00
abstract::1. A method has been developed and described for obtaining accurate thermal diffusivity values for dental cements and other restorative materials. This method employs specimens of a short cylindrical geometry which are readily fabricated from simply-constructed molds. 2. Results obtained for polycarboxylate and glass-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600120801
更新日期:1981-12-01 00:00:00
abstract::Stem cells are remarkable, and stem cell-based tissue engineering is an emerging field of biomedical science aiming to restore damaged tissue or organs. In dentistry and reconstructive facial surgery, it is of great interest to restore lost teeth or craniofacial bone defects using stem cell-mediated therapy. In the cr...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034515603972
更新日期:2015-11-01 00:00:00
abstract::Changes in stimulated and non-stimulated whole saliva flow rates were measured in 11 Hodgkin's disease patients who received therapeutic doses of radiation to a mantle field at the M. D. Anderson Hospital in Houston, Texas. Salivary flow rates were examined before, during, and after radiotherapy. Mean flow rate reduct...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670021801
更新日期:1988-02-01 00:00:00
abstract::Fluid transudation through simplified dentin adhesives can occur in bonded vital crown dentin, since these adhesives behave as permeable membranes after polymerization. The effect of adhesive permeability in endodontically treated teeth is unknown. This study examined the hypothesis that in vivo fluid movement through...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/154405910508400303
更新日期:2005-03-01 00:00:00
abstract::In this study, we investigated whether selective activation of nociceptive primary afferent fibers by capsaicin would induce modulations on tooth-pulp-evoked sensory or inhibitory masseter reflex responses in healthy human subjects. The contribution of central N-methyl-D-aspartate (NMDA) receptor mechanisms in capsaic...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760090801
更新日期:1997-09-01 00:00:00
abstract::Thermal diffusivity, a property related to the thermal insulative efficiency of a material, was measured in nine glass-ionomer cements and compared with results from a silicate and a polycarboxylate cement. Each cement was mixed at various powder-liquid ratios (P/L) and moulded into a rectangular prism of approximate ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660051001
更新日期:1987-05-01 00:00:00
abstract::The tooth resistance measuring instrument was compared to the traditional method of the explorer examination for the detection of occlusal carious lesions. The findings of the instrument were more sensitive as compared to the traditional method when verified by a histological examination. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570020801
更新日期:1978-02-01 00:00:00
abstract::Fibroblast growth factor (FGF) signaling has been implicated in the regulation of osteogenesis in both intramembranous and endochondral ossifications. In the developing palate, the anterior bony palate forms by direct differentiation of cranial neural crest (CNC)-derived mesenchymal cells, but the signals that regulat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517750141
更新日期:2018-05-01 00:00:00
abstract::Six subjects wore intra-oral devices carrying eight bovine enamel blocks which were covered with a layer of S. mutans. They rinsed their mouths for five sec, one min, or multiples of one min with a 5 or 10% glucose (G) solution. Demineralization was measured after 45 min by determining the change in iodide permeabilit...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650021001
更新日期:1986-02-01 00:00:00
abstract::The treatment of periodontitis/peri-implantitis involves the reduction/eradication of periopathogens. After therapy, beneficial and pathogenic species recolonize the subgingival area. The dynamics of recolonization and especially the role of the supragingival environment in this process are still not well-understood. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400409
更新日期:2005-04-01 00:00:00
abstract::Clinical studies have shown that metabolic syndrome (MetS) is associated with increased risk of developing periodontitis. However, the underlying mechanisms remain largely unknown. Since it is known that lipopolysaccharide (LPS)-activated toll-like receptor 4 signaling pathways play a crucial role in periodontitis, we...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514561658
更新日期:2015-02-01 00:00:00
abstract::Molar teeth of four groups of Osborne-Mendel rats, kept on a cariogenic diet, were treated once per day for 48 days with either distilled water (solution C), a solution containing 0.05% chlorhexidine gluconate and 0.04% NaF, pH 5.8 (solution CXF), CXF plus 1000 ppm Sr (solution CXFS), or CXFS plus 1000 ppm Zn (solutio...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630100401
更新日期:1984-10-01 00:00:00
abstract::Enamel crystals in the demineralized zones in early caries lesions of human teeth were observed by high-resolution electron microscopy. The enamel crystals frequently exhibited perforations in their centers and defects of various sizes on their lateral surfaces. There were a number of small electron-lucent spots, sugg...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660110901
更新日期:1987-11-01 00:00:00
abstract::Acute or chronic inflammation comprises a highly prevalent type of orofacial pain and is mediated by the generation of endogenous agonists that activate numerous receptors expressed on terminals of trigeminal (TG) nociceptive afferent neurons. One such studied receptor is transient receptor potential vanilloid subtype...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034516653751
更新日期:2016-09-01 00:00:00
abstract::Alendronate (ALN) is an antiresorptive agent widely used for the treatment of osteoporosis. Its suppressive effect on osteoclasts has been extensively studied. However, the effect of ALN on bone formation is not as clear as its effect on resorption. The objective was to determine the effect of short-term ALN on bone f...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515592867
更新日期:2015-09-01 00:00:00
abstract::Synovial hyperplasia is a feature of degenerative temporomandibular joint (TMJ) disease. However, the mechanism by which hyperplasia progresses in the TMJ is unknown. Based on the hypothesis that the oxidative stress generated by mechanical loading causes degenerative changes in the TMJ synovium, we investigated the g...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300807
更新日期:2004-08-01 00:00:00
abstract::Knoop hardness measurements of UV-polymerized dental composites showed that, at a certain depth below the surface, the degree of cure rapidly decreases. The depth of cure was found to be critically dependent on the UV source and exposure time used. A theoretical model was derived which was in quantitative accord with ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590050901
更新日期:1980-05-01 00:00:00
abstract::Gingival overgrowth is a common side-effect of the administration of cyclosporin A (CSA), phenytoin, and calcium blockers. To identify the signaling mechanisms possibly involved in the overgrowth, we examined how CSA affects the activities of MAP kinases and transcription factors in human gingival fibroblasts (HGF). T...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400609
更新日期:2005-06-01 00:00:00
abstract::Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this release was related to alloy composition, alloy microstructure, and alloy cytotoxicity (previously determined). Cell-culture medium was analyzed for alloy elements by flame atomic absorption. Concentrations of elements i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700060301
更新日期:1991-06-01 00:00:00
abstract::Cleidocranial dysplasia (CCD) is a skeletal dysplasia caused by heterozygous mutations of RUNX2, a gene that is essential for the mineralization of bone and tooth. We isolated primary dental pulp cells from a 10-y-old patient and tested their proliferative capacity, alkaline phosphatase activity, and ability to form m...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514566655
更新日期:2015-04-01 00:00:00
abstract::Dimensional alterations of the facial bone wall following tooth extractions in the esthetic zone have a profound effect on treatment outcomes. This prospective study in 39 patients is the first to investigate three-dimensional (3D) alterations of facial bone in the esthetic zone during the initial 8 wks following flap...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/0022034513506713
更新日期:2013-12-01 00:00:00
abstract::Samples of a base mental alloy were cast and welded together using a conventional welding procedure. The joints were loaded and placed either in a corrosive environment or in air for varying time periods. The tensile and shear strength of the joints was unaffected by the corrosive environment, and the joints, despite ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600021101
更新日期:1981-02-01 00:00:00
abstract::The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces and could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640030301
更新日期:1985-03-01 00:00:00
abstract::To date, the precise etiology of molar-incisor hypomineralization (MIH) is uncertain. Vitamin D plays a key role in hard tissue formation. Therefore, this study aimed to analyze the relationship between serum 25-hydroxy-vitamin D (25(OH)D) status and dental health data obtained from 1,048 children in a 10-year follow-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514561657
更新日期:2015-02-01 00:00:00
abstract::Heterozygous mutations in the RUNX2 (CBFA1) gene cause cleidocranial dysplasia, characterized by multiple supernumerary teeth. This suggests that Runx2 inhibits successional tooth formation. However, in Runx2 knockout mice, molar development arrests at the late bud stage, and lower molars are more severely affected th...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400206
更新日期:2005-02-01 00:00:00
abstract::Improved mechanical properties of resin composites have been reported to be a consequence of the addition of aldehyde to the resins. The objective of the present study was to examine whether this improvement could be attributed to an increased degree of conversion of double bonds. For this purpose, propanal was added ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730101101
更新日期:1994-10-01 00:00:00
abstract::Dental caries is a microbially mediated disease that can result in significant tooth structure degradation. Although the preponderance of lesions is treated by surgical intervention, various strategies have been developed for its noninvasive management. Here, we use a novel approach for noninvasive treatment based on ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515619370
更新日期:2016-03-01 00:00:00