Haem derivatives in the cerebrospinal fluid after intracranial haemorrhage.

Abstract:

:During the first 5 days after an intracranial haemorrhage, the red blood cells slowly haemolyse. Most of the oxyhaemoglobin, released in the cerebrospinal fluid, is transformed into bilirubin by an enzyme-dependent process. After 5 days, the haemolysis increases without a corresponding enhancement in the formation of bilirubin. Consequently, the oxyhaemoglobin concentration also increases. A spontaneous oxidation of the haem group follows and after about 10 days the proportions of oxy- and methaemoglobin are about the same. This process occurs independently of the cause of the haemorrhage.

journal_name

Eur Neurol

journal_title

European neurology

authors

Wahlgren NG,Lindquist C

doi

10.1159/000116339

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

216-21

issue

4

eissn

0014-3022

issn

1421-9913

journal_volume

26

pub_type

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