Abstract:
:The assessment and development of pain in children is reviewed in the first part of a two-part series. Assessment of pain in children has relied on self-report measures that have included visual analogue procedures using concrete stimuli for ratings. Behavioral assessment procedures are more sophisticated, but research on behavioral assessment of pediatric pain has begun to emergy only recently. There has been very little research on the developmental aspects of pain tolerance and pain threshold in children. There are preliminary indications that children's thoughts and attitudes about pain may change with age in a manner that contributes to more intense feelings of pain in adolescence than childhood. Children undergoing painful medical procedures show declining emotional outbursts with age and increasing signs of self-control and muscular rigidity. Possibilities for integrating the study of the developmental aspects of pain with social learning theory, cognitive developmental theory, and the psychology of physical symptom perception are discussed.
journal_name
Painjournal_title
Painauthors
Lavigne JV,Schulein MJ,Hahn YSdoi
10.1016/0304-3959(86)90206-Xsubject
Has Abstractpub_date
1986-11-01 00:00:00pages
133-146issue
2eissn
0304-3959issn
1872-6623pii
00006396-198611000-00001journal_volume
27pub_type
杂志文章,评审相关文献
PAIN文献大全abstract::Plastic changes in the anterior cingulate cortex (ACC) are critical in pain hypersensitivity caused by peripheral nerves injury. The Notch signaling pathway has been shown to regulate synaptic differentiation and transmission. Therefore, this study was to investigate the function of the Notch signaling pathway in the ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000002014
更新日期:2021-01-01 00:00:00
abstract::Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish pop...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2012.07.023
更新日期:2012-12-01 00:00:00
abstract::Intense stress and fear have long been known to give rise to a suppression of pain termed "stress-induced analgesia", mediated by brainstem pain-modulating circuitry, including pain-inhibiting neurons of the rostral ventromedial medulla. However, stress does not invariably suppress pain, and indeed, may exacerbate it....
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2009.01.011
更新日期:2009-04-01 00:00:00
abstract::Our objectives were to determine whether procedural pain and glucose exposure are associated with altered structural and functional brain development differently in preterm males and females, and neurodevelopment at 18-month corrected age. Fifty-one very preterm neonates (22 males; median [interquartile range] gestati...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001123
更新日期:2018-03-01 00:00:00
abstract::This study was designed to investigate the relative efficacy of cognitive-behavioral group treatment, including relaxation training, in comparison with a control condition in a sample of 20 outpatients with chronic low back pain. Subjects in both conditions also received the same physiotherapy back-education and exerc...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(92)90082-M
更新日期:1992-03-01 00:00:00
abstract::Contrary to a clinical aphorism that early head and neck cancer is painless, we show that patients who develop head and neck cancer experience significant pain at the time of initial diagnosis. We compared orofacial pain sensitivity in groups of patients with normal oral mucosa, oral precancer, and newly diagnosed ora...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2011.02.009
更新日期:2011-05-01 00:00:00
abstract::Moderate to severe chronic pain affects 1 in 5 adults and its impact increases with age. People with chronic pain that interferes with their lives have an increased risk of mortality. Identifying how interfering chronic pain can lead to mortality may highlight potential intervention strategies. This study uses a novel...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001193
更新日期:2018-06-01 00:00:00
abstract::Chronic posttraumatic headache (PTH) is among the most common and disabling sequelae of traumatic brain injury (TBI). Current PTH treatments are often only partially effective and have problematic side effects. We previously showed in a small randomized trial of patients with chronic nontraumatic headaches that manipu...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001983
更新日期:2020-12-01 00:00:00
abstract::The efficacy of amitriptyline was evaluated in 28 patients with chronic oral-facial pain. Most of the patients had evidence of musculoskeletal pain while some had a history suggesting pain of neurogenic origin. Two patients had mixed elements of neurogenic and musculoskeletal pain. Amitriptyline was more effective tha...
journal_title:Pain
pub_type: 临床试验,杂志文章
doi:10.1016/0304-3959(87)90036-4
更新日期:1987-11-01 00:00:00
abstract::The blockade of spinal glycine receptors with intrathecal (i.t.) strychnine produces segmentally-localized allodynia in the rat; a reversible and highly reproducible effect that is attained without peripheral or central nerve injury. We investigated the effect of i.v. mexiletine, an orally active congener of lidocaine...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/s0304-3959(97)00021-3
更新日期:1997-09-01 00:00:00
abstract::The left dorsolateral prefrontal cortex (DLPFC) is involved in the experience and modulation of pain, and may be an important node linking pain and cognition. Repetitive transcranial magnetic stimulation (rTMS) to the left DLPFC can reduce chronic and experimental pain. However, whether left DLPFC rTMS can influence t...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001350
更新日期:2018-12-01 00:00:00
abstract::Sendide is a selective and extremely potent antagonist of neurokinin-1 (NK1) receptors in the mouse spinal cord. The antinociceptive activities of sendide, an antagonist of NK1 receptors, and its analogue, [D-Trp7]sendide have been examined after intrathecal (i.t.) administrations in the mouse paw formalin test. Intra...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(94)00107-P
更新日期:1995-02-01 00:00:00
abstract::Tissue acidosis due to ischemia occurs under several pathological conditions and is believed to contribute to pain in these circumstances. TRPV1, TRPA1, and ASICs are known to be sensitive to acidic pH. Addressing their possible role in acidosis perception, the respective antagonists BCTC, A-967079, and amiloride were...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001848
更新日期:2020-07-01 00:00:00
abstract::Fourteen patients whose post-herpetic neuralgia could not be alleviated by conventional methods were treated with cryocautery using a stick of solid carbon dioxide (dry ice) applied directly to the hyperesthetic skin areas of the cutaneous scars. Follow-up evaluation revealed that 5 of 14 subjects maintained excellent...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(80)90049-4
更新日期:1980-12-01 00:00:00
abstract::The spinal gray matter region around the central canal, lamina X, is critically involved in somatosensory processing and visceral nociception. Although several classes of primary afferent fibers terminate or decussate in this area, little is known about organization and functional significance of the afferent supply o...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001586
更新日期:2019-09-01 00:00:00
abstract::The effects of intrathecal administration of substance P and N-methyl-D-aspartate (NMDA) were studied in the formalin test in mice. Both substances were administered 5 min before injection of formalin into the hind paw. Co-administration of substance P and NMDA intensified the response in both the 1st (0-10 min) and t...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(92)90260-I
更新日期:1992-11-01 00:00:00
abstract::In the skin surrounding a site of injury, hyperalgesia develops to mechanical stimuli. Two types of secondary hyperalgesia (to light touch and punctate stimuli) have recently been differentiated, based on different durations and sizes of the area involved. We studied secondary hyperalgesia in a subject who had a loss ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(93)90077-3
更新日期:1993-05-01 00:00:00
abstract::Exacerbation of pain by chronic stress and comorbidity of pain with stress-related psychiatric disorders, including anxiety and depression, represent significant clinical challenges. However, the underlying mechanisms still remain unclear. Here, we investigated whether chronic forced swim stress (CFSS)-induced exacerb...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000000827
更新日期:2017-04-01 00:00:00
abstract::This experiment had three goals: 1. To identify the basis of sucking-induced analgesia in healthy, term, newborn humans undergoing the painful, routine, procedure of heel lance and blood collection. 2. To evaluate how taste-induced and sucking-induced analgesias combine to combat pain. 3. To determine whether facial g...
journal_title:Pain
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0304-3959(99)00166-9
更新日期:1999-12-01 00:00:00
abstract::Microglia-neuron signalling in the spinal cord is a key mediator of mechanical allodynia caused by peripheral nerve injury. We recently reported sex differences in microglia in pain signalling in mice: spinal mechanisms underlying nerve injury-induced allodynia are microglial dependent in male but not female mice. Whe...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001265
更新日期:2018-09-01 00:00:00
abstract::Thirty-eight patients maintained on opioid analgesics for non-malignant pain were retrospectively evaluated to determine the indications, course, safety and efficacy of this therapy. Oxycodone was used by 12 patients, methadone by 7, and levorphanol by 5; others were treated with propoxyphene, meperidine, codeine, pen...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(86)90091-6
更新日期:1986-05-01 00:00:00
abstract::High-quality information on the potential benefit and harm of a drug is required for patients and clinicians to make informed treatment decisions and to enable cost-effectiveness modeling to be undertaken. This systematic review describes the collection and reporting of adverse event data as presented in published cli...
journal_title:Pain
pub_type: 杂志文章,评审
doi:10.1016/j.pain.2012.08.012
更新日期:2013-02-01 00:00:00
abstract::The behavioural response of infant rats to intraplantar injection of formalin consists of specific directed behaviours (limb flexion, shaking and licking the injected paw) and non-specific behaviours that are also induced by non-nociceptive stimulation (squirming, hind limb kicks and whole body jerks), with specific i...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(94)00277-L
更新日期:1995-09-01 00:00:00
abstract::In 1864, W. Mitchell and colleagues first described the clinical syndrome which came to be known as 'causalgia'. Since that time, the concept of sympathetically related pain has evolved. There is general agreement that profound emotional and behavioural changes can follow these types of pain. Opinions have varied wide...
journal_title:Pain
pub_type: 杂志文章,评审
doi:10.1016/0304-3959(92)90241-3
更新日期:1992-06-01 00:00:00
abstract::Heterotopic noxious counterstimulation (HNCS) by the application of a sustained noxious stimulus has been shown to inhibit nociceptive processes and decrease pain induced by a competing noxious stimulus. However, it is still not clear how attentional processes contribute to these effects. The main objective of this st...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2012.05.019
更新日期:2012-08-01 00:00:00
abstract::A visual analog scale (VAS) method of assessing headache pain was compared with a standard categorical four-grade scale (4GS) in a randomized, placebo-controlled, double-blind, clinical trial involving 792 treated migraine outpatients who received oral rizatriptan 5 mg, sumatriptan 50 mg, or placebo for a moderate or ...
journal_title:Pain
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0304-3959(01)00315-3
更新日期:2001-08-01 00:00:00
abstract::Genetic polymorphisms result in absent enzyme activity of CYP2D6 (poor metabolizers, PM) in about 10% of the Caucasian population. This study investigates whether the PM genotype has an impact on the response to tramadol analgesia in postoperative patients. A prospective study design was used and 300 patients recoveri...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/s0304-3959(03)00212-4
更新日期:2003-09-01 00:00:00
abstract::The purpose of this study is to analyze cancer breakthrough pain (BP) characteristics and how BP responds to conventional cancer pain management. Seventy-four cancer pain patients with worst pain severity >or=4 out of 10 completed the Brief Pain Inventory (BPI), Memorial Symptom Assessment Scale-Short Form, Functional...
journal_title:Pain
pub_type: 临床试验,杂志文章
doi:10.1016/s0304-3959(02)00293-2
更新日期:2003-01-01 00:00:00
abstract::The neurochemical effects of adenosine signaling in small-fiber neuropathy leading to neuropathic pain are yet to be explored in a direct manner. This study examined this system at the level of ligand (through the ectonucleotidase activity of prostatic acid phosphatase [PAP]) and adenosine A1 receptors (A1Rs) in resin...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001246
更新日期:2018-08-01 00:00:00
abstract::We investigated the effects of acute and of chronic morphine treatment on T-lymphocyte function and natural killer (NK) cell activity in rats receiving chronic constriction injury (CCI) of the sciatic nerve. T-Lymphocyte function was evaluated based on concanavalin-A (ConA)- and phytohemagglutinin (PHA)-induced spleno...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/S0304-3959(00)00323-7
更新日期:2000-11-01 00:00:00