Psychological aspects of reflex sympathetic dystrophy: a review of the adult and paediatric literature.

abstract：:This study investigated the effects of a single administration of 6-(4-methoxyphenyl)-5-methyl-3-pyridinyl-4-isoxazolo[4,5-c]pyridin-4(5H)-one (MMPIP), a negative allosteric modulator (NAM) of metabotropic glutamate receptor 7 (mGluR7), on pain and on affective and cognitive behavior in neuropathic mice. The activity ...

journal_title：Pain

authors： Palazzo E,Romano R,Luongo L,Boccella S,De Gregorio D,Giordano ME,Rossi F,Marabese I,Scafuro MA,de Novellis V,Maione S

更新日期：2015-06-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) is a ubiquitous signal transduction regulator, and Hsp90 inhibitors are in clinical development as cancer therapeutics. However, there have been very few studies on the impact of Hsp90 inhibitors on pain or analgesia, a serious concern for cancer patients. We previously found that Hsp90 i...

journal_title：Pain

authors： Stine C,Coleman DL,Flohrschutz AT,Thompson AL,Mishra S,Blagg BS,Largent-Milnes TM,Lei W,Streicher JM

更新日期：2020-08-01 00:00:00

abstract：:This study analyzed the relationship between the density of intraepidermal nerve fibers (IENF) and the characteristics of either nociceptive laser-evoked potentials (LEPs) or contact heat-evoked potentials (CHEPs) in patients with painful sensory polyneuropathy with the aim to determine which parameters of LEPs and CH...

journal_title：Pain

authors： Casanova-Molla J,Grau-Junyent JM,Morales M,Valls-Solé J

更新日期：2011-02-01 00:00:00

abstract：:Morphine (M) and hydromorphone (HM) are commonly used opioid analgesics for cancer pain. Opioid rotation is often necessary in the event of toxicity and/or inadequate analgesia. Equianalgesic reference tables based on single dose comparisons are possibly inadequate for patients on chronic treatment and developing tole...

journal_title：Pain

authors： Lawlor P,Turner K,Hanson J,Bruera E

更新日期：1997-08-01 00:00:00

abstract：:The opiate antagonist naloxone has been reported to cause pain relief. Therefore, the effect was determined of naloxone, injected intravenously, on the activity in single neurones of the dorsomedial part of the ventral nucleus (VDM) in the thalamus of rats under urethane anaesthesia elicited by electrical stimulation ...

journal_title：Pain

authors： Jurna I

更新日期：1988-12-01 00:00:00

abstract：:The local anesthetic lidocaine was injected into the dentate gyrus (DG) of alert, unrestrained rats 10 min prior to investigation within the formalin test. Regional anesthesia of the DG resulted in a reduction of pain scores when administered contralateral to the site of subcutaneous formalin injection. The analgesic ...

journal_title：Pain

authors： McKenna JE,Melzack R

更新日期：1992-04-01 00:00:00

abstract：:Aquaporin 1 (AQP1) is the archetypal member of a family of water channel proteins that contribute to water homeostasis in kidney, lung, and other tissues. Although there is limited evidence that aquaporins are expressed in the nervous system, AQP4 is expressed in glia and AQP9 is present on some neuronal and glial mit...

journal_title：Pain

authors： Shields SD,Mazario J,Skinner K,Basbaum AI

更新日期：2007-09-01 00:00:00

abstract：:Protein kinase signal transduction pathways play critical roles in regulating nociception. Here we show that c-kit, a tyrosine kinase receptor, is expressed in lamina I and II layer of the dorsal horn. Moreover, the superficial c-kit(+) fibers originate from the dorsal root ganglion, and c-kit in lamina II inner layer...

journal_title：Pain

authors： Sun YG,Gracias NG,Drobish JK,Vasko MR,Gereau RW,Chen ZF

更新日期：2009-07-01 00:00:00

abstract：:Is a person's response to one noxious stimulus similar to his/her responses to other noxious stimuli? This long-investigated topic in pain research has provided inconclusive results. In the present study, 2 samples were studied: one using 60 healthy volunteers and the other using 29 patients with coronary artery disea...

journal_title：Pain

authors： Janal MN,Glusman M,Kuhl JP,Clark WC

更新日期：1994-09-01 00:00:00

abstract：:The processes of individual adaptation to chronic pain are complex and occur across multiple domains. We examined the social, cognitive, and affective context of daily pain adaptation in individuals with fibromyalgia and osteoarthritis. By using a sample of 260 women with fibromyalgia or osteoarthritis, we examined th...

journal_title：Pain

authors： Sturgeon JA,Zautra AJ,Arewasikporn A

更新日期：2014-02-01 00:00:00

abstract：:This study examined the adaptational classification stability of the multidimensional pain inventory (MPI) in two samples of female fibromyalgia syndrome patients. Retest resulted in one-third of patients being assigned to a different classification. Twenty patients had four repeated MPI assessments over a 10-month pe...

journal_title：Pain

authors： Broderick JE,Junghaenel DU,Turk DC

更新日期：2004-05-01 00:00:00

abstract：:Combined oral administration of morphine sulfate (MS) and the over-the-counter antitussive drug and N-methyl-D-aspartate receptor antagonist dextromethorphan (DM) prevented the development of tolerance to the antinociceptive effects of MS (15, 24, or 32 mg/kg) in rats. This combined oral treatment regimen also attenua...

journal_title：Pain

authors： Mao J,Price DD,Caruso FS,Mayer DJ

更新日期：1996-10-01 00:00:00

abstract：ABSTRACT:Efficacy of treatment is heavily dependent on experience and expectations. Moreover, humans can generalize from one experience to a perceptually similar but novel situation. We investigated whether and how this applies to pain relief, using ecologically valid tonic pain stimuli treated by surreptitiously lower...

journal_title：Pain

authors： Kampermann L,Tinnermann A,Büchel C

更新日期：2020-12-15 00:00:00

abstract：:Tactile, proprioceptive, and nociceptive information, including also chemosensory functions are expressed in the trigeminal nerve sensory response. To study differences in the processing of different stimulus qualities, we performed a study based on functional magnetic resonance imaging. The first trigeminal branch (o...

journal_title：Pain

authors： Iannilli E,Del Gratta C,Gerber JC,Romani GL,Hummel T

更新日期：2008-10-15 00:00:00

abstract：:The purpose of this study was to determine if some commonly used admission variables could predict treatment outcome on a multidisciplinary pain center. Specifically, it was designed as a prospective study of an index proposed by Maruta et al. The subjects were 104 patients. The 4 outcome measures used were staff judg...

journal_title：Pain

authors： Aronoff GM,Evans WO

更新日期：1982-09-01 00:00:00

abstract：:We have previously reported a novel method for producing chronic nociceptive behavior in rats following compression of the trigeminal ganglion. In the present study, we have further studied the role of demyelination in the development of prolonged nociceptive behavior in the trigeminal territory. For this purpose, lys...

journal_title：Pain

authors： Ahn DK,Lee SY,Han SR,Ju JS,Yang GY,Lee MK,Youn DH,Bae YC

更新日期：2009-11-01 00:00:00

abstract：:Individuals diagnosed with fibromyalgia syndrome (FMS) report chronic pain that is frequently worsened by physical activity and improved by rest. Palpation of muscle and tendinous structures suggests that nociceptors in deep tissues are abnormally sensitive in FMS, but methods of controlled mechanical stimulation of m...

journal_title：Pain

authors： Staud R,Cannon RC,Mauderli AP,Robinson ME,Price DD,Vierck CJ Jr

更新日期：2003-03-01 00:00:00

abstract：:Painful neuromas can cause severe loss of function and have great impact on the daily life of patients. Surgical management remains challenging; despite improving techniques, success rates are low. To accurately study the success of surgical neuroma treatment and factors predictive of outcome, a prospective follow-up ...

journal_title：Pain

authors： Stokvis A,van der Avoort DJC,van Neck JW,Hovius SER,Coert HJ

更新日期：2010-12-01 00:00:00

abstract：:Chronic complications of traumatic brain injury represent one of the greatest financial burdens and sources of suffering in the society today. A substantial number of these patients suffer from posttraumatic headache (PTH), which is typically associated with tactile allodynia. Unfortunately, this phenomenon has been u...

journal_title：Pain

authors： Wattiez AS,Castonguay WC,Gaul OJ,Waite JS,Schmidt CM,Reis AS,Rea BJ,Sowers LP,Cintrón-Pérez CJ,Vázquez-Rosa E,Pieper AA,Russo AF

更新日期：2020-10-02 00:00:00

abstract：:Ninety-two knees in 46 patients were evaluated with regard to pain: in 51 of these knees, implantation of a hinged endoprosthesis had been performed. The reliability and validity of 2 pain evaluation methods were assessed: the knee-pain questionnaire method (standard version including 10 questions and modified version...

journal_title：Pain

authors： Boeckstyns MEH,Backer M

更新日期：1989-07-01 00:00:00

abstract：ABSTRACT:Mobile health (mHealth) apps have the potential to enhance pain management through the use of daily diaries, medication and appointment reminders, education, and facilitating communication between patients and providers. Although many pain management apps exist, the extent to which these apps use evidence-base...

journal_title：Pain

authors： Gamwell KL,Kollin SR,Gibler RC,Bedree H,Bieniak KH,Jagpal A,Tran ST,Hommel KA,Ramsey RR

更新日期：2020-09-22 00:00:00

abstract：:A variety of molecules released by inflammatory reactions in the dorsal root and dorsal root ganglion (DRG) may play important roles in the pathology of neuronal abnormalities in lumbar disc herniation. In order to elucidate the pathophysiological mechanisms of painful radiculopathy, secondary to lumbar disc herniatio...

journal_title：Pain

authors： Obata K,Tsujino H,Yamanaka H,Yi D,Fukuoka T,Hashimoto N,Yonenobu K,Yoshikawa H,Noguchi K

更新日期：2002-09-01 00:00:00

abstract：:The objective of this study was to examine pain as a predictor of frailty over 18 years of follow-up among older Mexican Americans who were nonfrail at baseline. Data were from a prospective cohort study of 1545 community-dwelling Mexican Americans aged ≥67 years from the Hispanic Established Populations for the Epide...

journal_title：Pain

authors： Sodhi JK,Karmarkar A,Raji M,Markides KS,Ottenbacher KJ,Al Snih S

更新日期：2020-01-01 00:00:00

abstract：:A descriptive, longitudinal design was used to examine changes in current, worst, and least pain intensity during hospitalization for a vaso-occlusive episode in children with sickle cell disease. Other dimensions of the pain experience including location and quality were also evaluated. Children reported severe pain ...

journal_title：Pain

authors： Jacob E,Miaskowski C,Savedra M,Beyer JE,Treadwell M,Styles L

更新日期：2003-03-01 00:00:00

abstract：:There is considerable evidence to implicate N-methyl-D-aspartate (NMDA) receptor activation in the mechanisms that underly thermal hyperalgesia in the spinal cord. As many of the effects of NMDA receptor activation appear to be ultimately mediated through production of nitric oxide (NO), recent reports have begun to d...

journal_title：Pain

authors： Meller ST,Gebhart GF

更新日期：1993-02-01 00:00:00

abstract：:A double-blind placebo-controlled crossover trial was used to determine the effects of topical ketamine, an N-methyl-d-aspartate (NMDA) receptor antagonist, on the sensory disturbances in 20 patients with complex regional pain syndrome (CRPS). On two occasions separated by at least one week, sensory tests to light tou...

journal_title：Pain

authors： Finch PM,Knudsen L,Drummond PD

更新日期：2009-11-01 00:00:00

abstract：:The role of prostanoids in nociception is well established. The headache eliciting effects of prostacyclin (prostaglandin I(2), (PGI(2))) and its possible mechanisms had previously not been systematically studied in man. We hypothesized that infusion of PGI(2) might induce headache and vasodilatation of cranial vessel...

journal_title：Pain

authors： Wienecke T,Olesen J,Oturai PS,Ashina M

更新日期：2008-09-30 00:00:00

abstract：:Regular physical activity in healthy individuals prevents development of chronic musculoskeletal pain; however, the mechanisms underlying this exercise-induced analgesia are not well understood. Interleukin-10 (IL-10), an antiinflammatory cytokine that can reduce nociceptor sensitization, increases during regular phys...

journal_title：Pain

authors： Leung A,Gregory NS,Allen LH,Sluka KA

更新日期：2016-01-01 00:00:00

abstract：:For genetic research to contribute more fully to furthering our knowledge of neuropathic pain, we require an agreed, valid, and feasible approach to phenotyping, to allow collaboration and replication in samples of sufficient size. Results from genetic studies on neuropathic pain have been inconsistent and have met wi...

journal_title：Pain

authors： van Hecke O,Kamerman PR,Attal N,Baron R,Bjornsdottir G,Bennett DLH,Bennett MI,Bouhassira D,Diatchenko L,Freeman R,Freynhagen R,Haanpää M,Jensen TS,Raja SN,Rice ASC,Seltzer Z,Thorgeirsson TE,Yarnitsky D,Smith BH

更新日期：2015-11-01 00:00:00

abstract：:To determine the incidence of pain related sexual dysfunction 1 year after inguinal herniorrhaphy and to assess the impact pain has on sexual function. In contrast to the well-described about 10% risk of chronic wound related pain after inguinal herniorrhaphy, chronic genital pain, dysejaculation, and sexual dysfuncti...

journal_title：Pain

authors： Aasvang EK,Møhl B,Bay-Nielsen M,Kehlet H

更新日期：2006-06-01 00:00:00