Pain related sexual dysfunction after inguinal herniorrhaphy.

abstract：:Multidimensional models of pain processing distinguish the sensory, motivational, and affective components of the pain experience. Efforts to understand underlying mechanisms have focused on isolating the roles of specific brain structures, including both limbic and non-limbic cortical areas, in the processing of noci...

journal_title：Pain

authors： Uhelski ML,Davis MA,Fuchs PN

更新日期：2012-04-01 00:00:00

abstract：:A controlled trial of diamorphine (diacetylmorphine, heroin) and morphine is reported in which the two drugs were administered regularly by mouth in individually determined effective analgesic doses. Elixirs contained cocaine hydrochloride 10 mg/dose; other drugs were prescribed when indicated clinically. 699 patients...

journal_title：Pain

authors： Twycross RG

更新日期：1977-04-01 00:00:00

abstract：:The perception of pain is highly variable. It depends on bottom-up-mediated factors like stimulus intensity and top-down-mediated factors like expectations. In the brain, pain is associated with a complex pattern of neuronal responses including evoked potentials and induced responses at alpha and gamma frequencies. Al...

journal_title：Pain

authors： Tiemann L,May ES,Postorino M,Schulz E,Nickel MM,Bingel U,Ploner M

更新日期：2015-02-01 00:00:00

abstract：:Topically applied norepinephrine, dopamine, serotonin, GABA and glycine, and systemically administered clonidine, L-DOPA (plus carbidopa) and 5-hydroxytryptophan completely suppressed the cutaneous hyper-irritability produced in the trigeminal sensory distribution by picrotoxin overlying the caudal medulla. Cholinergi...

journal_title：Pain

authors： Sakai Y,Nishijima Y,Mikuni N,Iwata N

更新日期：1981-08-01 00:00:00

abstract：:TNFalpha plays a pivotal role in rheumatoid arthritis (RA) but little is known of the mechanisms that link the inflammatory and nociceptive effects of TNFalpha. We have established a murine model of TNFalpha-induced TRPV1-dependent bilateral thermal hyperalgesia that then allowed us to identify distinct peripheral mec...

journal_title：Pain

authors： Russell FA,Fernandes ES,Courade JP,Keeble JE,Brain SD

更新日期：2009-04-01 00:00:00

abstract：:Substance P like immunoreactivity (SPLI) and total protein (TP) concentrations in plasma and saliva were measured in 80 healthy female patients divided into the following four groups: women in group 1 were not pregnant and they were awaiting tubal ligation; women in group 2 were not pregnant but they experienced acute...

journal_title：Pain

authors： Dalby PL,Ramanathan S,Rudy TE,Roy L,Amenta JS,Aber A

更新日期：1997-02-01 00:00:00

abstract：:Neuropathic pain behaviour is not observed in neonatal rats and tactile allodynia does not develop in the spared nerve injury (SNI) model until rats are 4 weeks of age at the time of surgery. Since activated spinal microglia are known to play a key role in neuropathic pain, we have investigated whether the microglial ...

journal_title：Pain

authors： Moss A,Beggs S,Vega-Avelaira D,Costigan M,Hathway GJ,Salter MW,Fitzgerald M

更新日期：2007-04-01 00:00:00

abstract：:Although several studies have shown that spouses of chronic pain patients may experience clinically significant depressive symptoms few studies have comprehensively examined the role of both patient and spouse-related factors in the development and maintenance of this emotional distress. Twenty-nine married male chron...

journal_title：Pain

authors： Schwartz L,Slater MA,Birchler GR,Atkinson HJ

更新日期：1991-01-01 00:00:00

abstract：:Increased blood pressure and sweet taste are often associated with decreased pain sensitivity. Animal research suggests that endogenous opioids are involved in both these relationships. Fifty-eight healthy young adults (36 male, 22 female) participated in two sessions receiving a placebo tablet or 50mg of naltrexone o...

journal_title：Pain

authors： Lewkowski MD,Young SN,Ghosh S,Ditto B

更新日期：2008-03-01 00:00:00

abstract：:Ketanserin, a selective S2 serotonergic antagonist, was assessed against placebo in a double-blind cross-over study of 16 patients with chronic peripheral burning pain. Nine of these had signs of reflex sympathetic dystrophy (RSD). All patients underwent 4 intravenous regional treatments, 2 with ketanserin (10 mg for ...

journal_title：Pain

authors： Hanna MH,Peat SJ

更新日期：1989-08-01 00:00:00

abstract：:Expectations modulate the subjective experience of pain by increasing sensitivity to nociceptive inputs, an effect mediated by brain regions such as the insula. However, it is still unknown whether the neural structures underlying pain expectancy hold sensory-specific information or, alternatively, code for modality-i...

journal_title：Pain

authors： Sharvit G,Corradi-DellʼAcqua C,Vuilleumier P

更新日期：2018-08-01 00:00:00

abstract：ABSTRACT:Mobile health (mHealth) apps have the potential to enhance pain management through the use of daily diaries, medication and appointment reminders, education, and facilitating communication between patients and providers. Although many pain management apps exist, the extent to which these apps use evidence-base...

journal_title：Pain

authors： Gamwell KL,Kollin SR,Gibler RC,Bedree H,Bieniak KH,Jagpal A,Tran ST,Hommel KA,Ramsey RR

更新日期：2020-09-22 00:00:00

abstract：:We aimed to investigate whether small-fibre pathology, a common skin biopsy finding in patients with fibromyalgia, implies clinically important abnormalities of somatosensory system function and verify whether it is associated with voltage-gated sodium channel variants. In 57 consecutively enrolled patients with fibro...

journal_title：Pain

authors： Fasolino A,Di Stefano G,Leone C,Galosi E,Gioia C,Lucchino B,Terracciano A,Di Franco M,Cruccu G,Truini A

更新日期：2020-10-01 00:00:00

abstract：:Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular venous blood of adult migraineurs during acute migraine attacks, it remains unknown whether CGRP is increased outside of attacks in jugular or cubital venous blood. The aim of the present study was to compare interictal plasma lev...

journal_title：Pain

authors： Ashina M,Bendtsen L,Jensen R,Schifter S,Olesen J

更新日期：2000-05-01 00:00:00

abstract：:In order to understand how nociceptive information is processed in the spinal dorsal horn we need to unravel the complex synaptic circuits involving interneurons, which constitute the vast majority of the neurons in laminae I-III. The main limitation has been the difficulty in defining functional populations among the...

journal_title：Pain

authors： Polgár E,Sardella TCP,Tiong SYX,Locke S,Watanabe M,Todd AJ

更新日期：2013-12-01 00:00:00

abstract：:Pain and thermal sensitivity thresholds in healthy volunteers were examined for diurnal variations. The subjects were 11 men aged between 22 and 27 years (means = 23.5, S.D. = 1.5). Data were collected for 2 days, with 7 measurements per day. To ensure the pain specificity of the results the subliminal modality, i.e.,...

journal_title：Pain

authors： Strian F,Lautenbacher S,Galfe G,Hölzl R

更新日期：1989-01-01 00:00:00

abstract：:Acute zoster infection may be followed by a chronic pain syndrome, i.e., postherpetic neuralgia (PHN). Besides older age, the intensity of pain and neuronal damage within the acutely affected body region are regarded as predictors or risk factors for PHN. As an alternative approach an underlying peripheral polyneuropa...

journal_title：Pain

authors： Baron R,Haendler G,Schulte H

更新日期：1997-11-01 00:00:00

abstract：:The analgesic effect of systemic ibuprofen was investigated with two human experimental pain models: (i) static mechanical stimulation of the inter digital web between the 2nd and 3rd finger and (ii) primary and secondary hyperalgesia induced by a 7-min burn injury on the calf. In each double-blind, randomized, two-wa...

journal_title：Pain

authors： Petersen KL,Brennum J,Dahl JB

更新日期：1997-04-01 00:00:00

abstract：:Analgesic response, incidental pain and pain mechanism were evaluated in order to predict the chances of pain relief in advanced cancer patients. In an observation period of about 2 months, 130 patients were followed at home until death using only a pharmacological approach to control pain according to the WHO ladders...

journal_title：Pain

authors： Mercadante S,Maddaloni S,Roccella S,Salvaggio L

更新日期：1992-08-01 00:00:00

abstract：:Both physicians and nurses are responsible for adequate pain management. The aim of this study was to assess pain management behavior of physicians and nurses, and to evaluate the effects of a Pain Monitoring Program for nurses on the extent to which nurses administer analgesics. The Pain Monitoring Program consisted ...

journal_title：Pain

authors： de Rond MEJ,de Wit R,van Dam FSAM,Muller MJ

更新日期：2000-12-15 00:00:00

abstract：:Patients with chronic pain often report being sensitive to pain at night before falling asleep, a time when the synchronization of cortical activity is initiated. However, how cortical activity relates to pain sensitivity is still unclear. Because sleep is characterized by enhanced cortical delta power, we hypothesize...

journal_title：Pain

authors： Li YD,Ge J,Luo YJ,Xu W,Wang J,Lazarus M,Hong ZY,Qu WM,Huang ZL

更新日期：2020-02-01 00:00:00

abstract：:Few surveys have been performed to define the characteristics and impact of breakthrough pain in the cancer population. In this cross-sectional survey of inpatients with cancer, patients responded to a structured interview (the Breakthrough Pain Questionnaire) designed to characterize breakthrough pain, and also compl...

journal_title：Pain

authors： Portenoy RK,Payne D,Jacobsen P

更新日期：1999-05-01 00:00:00

abstract：:Pain evoked potentials (EPs) have been used in the last two decades as means of obtaining objective measures of pain, in clinical and experimental setups. The possibility that the pain EP wave contains elements of the endogenous P300 potential rather than being a neurophysiological correlate of pain has been raised by...

journal_title：Pain

authors： Zaslansky R,Sprecher E,Tenke EC,Hemli AJ,Yarnitsky D

更新日期：1996-07-01 00:00:00

abstract：:Bone is one of the leading sites of metastasis for frequently diagnosed malignancies, including those arising in the breast, prostate and lung. Although these cancers develop unnoticed and are painless in their primary sites, bone metastases result in debilitating pain. Deeper investigation of this pain may reveal eti...

journal_title：Pain

authors： Slosky LM,BassiriRad NM,Symons AM,Thompson M,Doyle T,Forte BL,Staatz WD,Bui L,Neumann WL,Mantyh PW,Salvemini D,Largent-Milnes TM,Vanderah TW

更新日期：2016-11-01 00:00:00

abstract：:Monoclonal antibodies against GD(2) ganglioside, such as ch14.18, the human-mouse chimeric antibody, have been shown to be effective for the treatment of neuroblastoma. However, treatment is associated with generalized, relatively opiate-resistant pain. We investigated if a point mutation in ch14.18 antibody (hu14.18K...

journal_title：Pain

authors： Sorkin LS,Otto M,Baldwin WM 3rd,Vail E,Gillies SD,Handgretinger R,Barfield RC,Yu HM,Yu AL

更新日期：2010-04-01 00:00:00

abstract：:The present study observed the expression of the 5-hydroxytryptamine (5-HT) (1A) receptor mRNA in the lumbar spinal dorsal horn neurons following carrageenan inflammation using in situ hybridization (ISH). We also studied the co-localization of 5-HT(1A) receptor mRNA and gamma-amino butyric acid (GABA) or enkephalin (...

journal_title：Pain

authors： Zhang YQ,Gao X,Ji GC,Huang YL,Wu GC,Zhao ZQ

更新日期：2002-08-01 00:00:00

abstract：:Neuropathic pain affects millions of people worldwide, causing substantial disability and greatly impairing quality of life. Commonly used analgesics or antihyperalgesic compounds are generally characterized by limited therapeutic outcomes. Thus, there is a compelling need for novel therapeutic strategies able to prev...

journal_title：Pain

authors： Di Cesare Mannelli L,Cinci L,Micheli L,Zanardelli M,Pacini A,McIntosh JM,Ghelardini C

更新日期：2014-10-01 00:00:00

abstract：:Effective assessment and management of pain in patients with cancer is strengthened by the patient's report of how much pain interferes with daily functioning. This requires a clear delineation of different levels of pain interference. We derived optimal cutpoints for differentiating between mild, moderate, and severe...

journal_title：Pain

authors： Shi Q,Mendoza TR,Dueck AC,Ma H,Zhang J,Qian Y,Bhowmik D,Cleeland CS

更新日期：2017-06-01 00:00:00

abstract：:The discTRODE probe applies radiofrequency (RF) current, heating the annulus to treat chronic discogenic low back pain. Randomized controlled studies have not been published. We assessed the long-term effect and safety aspects of percutaneous intradiscal radiofrequency thermocoagulation (PIRFT) with the discTRODE prob...

journal_title：Pain

authors： Kvarstein G,Måwe L,Indahl A,Hol PK,Tennøe B,Digernes R,Stubhaug A,Tønnessen TI,Beivik H

更新日期：2009-10-01 00:00:00

abstract：:The literature on cognitive and cognitive-behavioral methods for pain control is selectively reviewed, with particular focus on controlled studies. Such methods include the provision of preparatory information, cognitive coping skills or strategies, the provision of preparatory information plus some form of coping ski...

journal_title：Pain

authors： Tan SY

更新日期：1982-03-01 00:00:00