Abstract：
:Substance P like immunoreactivity (SPLI) and total protein (TP) concentrations in plasma and saliva were measured in 80 healthy female patients divided into the following four groups: women in group 1 were not pregnant and they were awaiting tubal ligation; women in group 2 were not pregnant but they experienced acute postoperative pain following hysterectomy; women in group 3 were pregnant and were awaiting elective cesarean section; and women in group 4 were in active labor and experienced acute labor pain. Pain intensity was assessed using verbal Likert pain scores. The absolute measured concentration of SPLI (SPLIabs) was divided by the TP concentration to obtain corrected SPLI (SPLIcorr) concentration. Results were expressed mean +/- 1 SE and analyzed using analysis of variance with 95% confidence (P < 0.05). SPLIcorr concentrations were 1.8 +/- 0.1, 1.8 +/- 0.2, 1.1 +/- 0.1 1.1 +/- 0.1 pg/mg protein in groups 1, 2, 3 and 4, respectively. Patients in both pregnant groups had significantly lower plasma SPLIcorr concentrations compared to the non-pregnant groups. However, the presence of acute postoperative pain or labor pain did not significantly alter plasma SPLIcorr concentrations. Saliva SPLI concentrations were not significantly different among the four groups.
journal_name
Painjournal_title
Painauthors
Dalby PL,Ramanathan S,Rudy TE,Roy L,Amenta JS,Aber Adoi
10.1016/S0304-3959(96)03258-7subject
Has Abstractpub_date
1997-02-01 00:00:00pages
263-267issue
3eissn
0304-3959issn
1872-6623pii
00006396-199702000-00007journal_volume
69pub_type
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