Identification of neck-shoulder disorders in a 1 year follow-up study. Validation Of a questionnaire-based method.

abstract：:Occupational activities such as lifting loads, working in constrained spaces, and training increase the risk of pain-related musculoskeletal disorders (MSDs) in military veterans. Few studies have investigated MSD and psychological disorder in veterans, and previous studies had limitations. This cross-sectional study ...

journal_title：Pain

authors： Kelsall HL,McKenzie DP,Forbes AB,Roberts MH,Urquhart DM,Sim MR

更新日期：2014-04-01 00:00:00

abstract：:In the present study 366 patients suffering acute or chronic musculoskeletal pain of different origin were given vibratory stimulation for the pain. Many of the patients had previously had treatments of various kinds without satisfactory relief. The effect of vibratory stimulation was assessed during and after stimula...

journal_title：Pain

authors： Lundeberg T,Nordemar R,Ottoson D

更新日期：1984-09-01 00:00:00

abstract：:Thirty subjects were given a placebo (intravenous saline), which was described as a known pain killer, once a week for 3 consecutive weeks. Experimental ischemic arm pain was produced prior to the placebo and again 1 h later. In a double blind procedure, half of the subjects received 10 mg of naloxone after placebo; t...

journal_title：Pain

authors： Grevert P,Albert LH,Goldstein A

更新日期：1983-06-01 00:00:00

abstract：:Forty patients with chronic pain below the waist level not amenable to conventional medical and/or surgical treatment were randomly assigned to one or two different methods of acupuncture, after studying the underlying pain mechanisms using a Multidisciplinary Pain Clinic approach and the differential spinal block (DS...

journal_title：Pain

authors： Ghia JN,Mao W,Toomey TC,Gregg JM

更新日期：1976-09-01 00:00:00

abstract：:The antinociception effect of clomipramine and the combination of clomipramine and morphine was evaluated using the constant temperature hot plate test, the increasing temperature hot plate test and the formalin test in mice. Both a single dose of clomipramine (10 mg/kg) given intraperitoneally (i.p.) and chronic clom...

journal_title：Pain

authors： Rosland JH,Hunskaar S,Hole K

更新日期：1988-06-01 00:00:00

abstract：:The effects of lateral reticular nucleus (LRN) stimulation on the responses to tooth pulp (TP) stimulation of neurons located in the trigeminal (V) sensory (39 units) and motor (33 units) nuclei were assessed in anesthetized rats. Only neurons which responded to TP stimulation with bursts of spikes that were in a cons...

journal_title：Pain

authors： Sotgiu ML,Bellinzona M

更新日期：1991-07-01 00:00:00

abstract：:Since many people with chronic fatigue present with pain and many people with chronic pain present with fatigue, we tested if fatigue would enhance the response to pain in male and female mice. We further tested for the activation of brainstem nuclei by the fatigue task using c-fos as a marker. Fatigue was induced by ...

journal_title：Pain

authors： Sluka KA,Rasmussen LA

更新日期：2010-02-01 00:00:00

abstract：:In knee osteoarthritis (OA), pain sensitization has been linked to a more severe symptomatology, but the prognostic implications of pain sensitivity in people undergoing conservative treatment such as physiotherapy are not established. This study aimed to prospectively investigate the association between features of p...

journal_title：Pain

authors： OʼLeary H,Smart KM,Moloney NA,Blake C,Doody CM

更新日期：2018-09-01 00:00:00

abstract：:A large sample of staff physicians and residents (n = 193) responded to a questionnaire in which they were asked to rate 10 pain descriptors for level of applicability to 4 common acute and chronic pain syndromes. The purpose of the study was to examine the extent to which physicians would agree on the ratings, and wh...

journal_title：Pain

authors： Tearnan BH,Dar R

更新日期：1986-07-01 00:00:00

abstract：:Chronic pain is more common in the elderly and impairs functioning and quality of life. Though obesity, defined by body mass index (BMI), has been associated with pain prevalence among older adults, the mechanism of this association remains unclear. We examined components of the metabolic syndrome, insulin resistance,...

journal_title：Pain

authors： Ray L,Lipton RB,Zimmerman ME,Katz MJ,Derby CA

更新日期：2011-01-01 00:00:00

abstract：:An experimental mononeuropathy was produced in rats by unilateral loose ligation of the sciatic nerve, with a contralateral sham surgery. Repeated bilateral sensory testing was performed over time to investigate any threshold differences between the loose ligature side and the contralateral control side. A prolonged r...

journal_title：Pain

authors： Kingery WS,Castellote JM,Wang EE

更新日期：1993-12-01 00:00:00

abstract：:Noxious C-fibre stimulation produces increased sensitivity within the injured area (primary hyperalgesia), and a surrounding zone of secondary hyperalgesia. As significant changes in nociceptive processing occur during development, we compared C-fibre induced primary and secondary hyperalgesia in rat pups aged 3, 10 a...

journal_title：Pain

authors： Walker SM,Meredith-Middleton J,Lickiss T,Moss A,Fitzgerald M

更新日期：2007-03-01 00:00:00

abstract：:To date, patients with bony metastases were only a small fraction of the samples studied, or they were entirely excluded. Patients with metastatic cancers, such as bone metastases, are more likely to report pain, compared to patients without metastatic cancer (50-74% and 15%, respectively). Their cancer pain results i...

journal_title：Pain

authors： Jane SW,Chen SL,Wilkie DJ,Lin YC,Foreman SW,Beaton RD,Fan JY,Lu MY,Wang YY,Lin YH,Liao MN

更新日期：2011-10-01 00:00:00

abstract：:Behavioral studies have suggested that placebo analgesia is partly mediated by the endogenous opioid system. Expanding on these results we have shown that the opioid-receptor-rich rostral anterior cingulate cortex (rACC) is activated in both placebo and opioid analgesia. However, there are also differences between the...

journal_title：Pain

authors： Petrovic P,Kalso E,Petersson KM,Andersson J,Fransson P,Ingvar M

更新日期：2010-07-01 00:00:00

abstract：:Neuropathic pain (NP) in cancer patients lacks standards for diagnosis. This study is aimed at reaching consensus on the application of the International Association for the Study of Pain (IASP) special interest group for neuropathic pain (NeuPSIG) criteria to the diagnosis of NP in cancer patients and on the relevanc...

journal_title：Pain

authors： Brunelli C,Bennett MI,Kaasa S,Fainsinger R,Sjgren P,Mercadante S,Lhre ET,Caraceni A,European Association for Palliative Care (EAPC) Research Network and International Association for the Study of Pain (IASP) Cancer Pain Special Interest

更新日期：2014-12-01 00:00:00

abstract：:Fourteen patients whose post-herpetic neuralgia could not be alleviated by conventional methods were treated with cryocautery using a stick of solid carbon dioxide (dry ice) applied directly to the hyperesthetic skin areas of the cutaneous scars. Follow-up evaluation revealed that 5 of 14 subjects maintained excellent...

journal_title：Pain

authors： Suzuki H,Ogawa S,Nakagawa H,Kanayama T,Taj K,Saitoh H,Ohshima Y

更新日期：1980-12-01 00:00:00

abstract：:The chronic pain syndrome inherited erythromelalgia (IEM) is attributed to mutations in the voltage-gated sodium channel (NaV) 1.7. Still, recent studies targeting NaV1.7 in clinical trials have provided conflicting results. Here, we differentiated induced pluripotent stem cells from IEM patients with the NaV1.7/I848T...

journal_title：Pain

authors： Meents JE,Bressan E,Sontag S,Foerster A,Hautvast P,Rösseler C,Hampl M,Schüler H,Goetzke R,Le TKC,Kleggetveit IP,Le Cann K,Kerth C,Rush AM,Rogers M,Kohl Z,Schmelz M,Wagner W,Jørum E,Namer B,Winner B,Zenke M,Lam

更新日期：2019-06-01 00:00:00

abstract：:Intense stress and fear have long been known to give rise to a suppression of pain termed "stress-induced analgesia", mediated by brainstem pain-modulating circuitry, including pain-inhibiting neurons of the rostral ventromedial medulla. However, stress does not invariably suppress pain, and indeed, may exacerbate it....

journal_title：Pain

authors： Martenson ME,Cetas JS,Heinricher MM

更新日期：2009-04-01 00:00:00

abstract：:Tailored treatment based on individual risk factors is an area with promise to improve options for pain relief. Musculoskeletal pain has a biopsychosocial nature, and multiple factors should be considered when determining risk for chronic pain. This study investigated whether subgroups comprised genetic and psychologi...

journal_title：Pain

authors： George SZ,Wallace MR,Wu SS,Moser MW,Wright TW,Farmer KW,Borsa PA,Parr JJ,Greenfield WH 3rd,Dai Y,Li H,Fillingim RB

更新日期：2015-01-01 00:00:00

abstract：:Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the body. It has been suggested that such side bias results from corti...

journal_title：Pain

authors： Leite-Almeida H,Cerqueira JJ,Wei H,Ribeiro-Costa N,Anjos-Martins H,Sousa N,Pertovaara A,Almeida A

更新日期：2012-11-01 00:00:00

abstract：:The effects of nitrous oxide (N2O) are thought to be mediated by several pharmacological pathways at different levels of the central nervous system. Here, we focus on excitatory glutamatergic transmission in the superficial dorsal horn of the spinal cord with respect to its importance for the nociceptive processing. T...

journal_title：Pain

authors： Georgiev SK,Kohno T,Ikoma M,Yamakura T,Baba H

更新日期：2008-01-01 00:00:00

abstract：:We have constructed and validated the Elderly Pain Caring Assessment 2 (EPCA-2) an 8 items behavioural scale to rate the intensity of pain in non-verbally communicating older (age 65 years) patients (NVC-OP). It was postulated that the assessed pain had two dimensions (signs outside and during caregiving). The first v...

journal_title：Pain

authors： Morello R,Jean A,Alix M,Sellin-Peres D,Fermanian J

更新日期：2007-12-15 00:00:00

abstract：:The investigation of neurotransmitter systems in placebo and nocebo effects has improved our understanding of these phenomena. Yet, most studies involve healthy participants. Because the pain modulatory system may differ in healthy participants and patients with chronic pain, it is important to investigate the evidenc...

journal_title：Pain

authors： Skyt I,Lunde SJ,Baastrup C,Svensson P,Jensen TS,Vase L

更新日期：2020-01-01 00:00:00

abstract：:Substance P like immunoreactivity (SPLI) and total protein (TP) concentrations in plasma and saliva were measured in 80 healthy female patients divided into the following four groups: women in group 1 were not pregnant and they were awaiting tubal ligation; women in group 2 were not pregnant but they experienced acute...

journal_title：Pain

authors： Dalby PL,Ramanathan S,Rudy TE,Roy L,Amenta JS,Aber A

更新日期：1997-02-01 00:00:00

abstract：:Migraine headache is one of the most common neurological disorders. The pathological conditions that directly initiate afferent pain signaling are poorly understood. In trigeminal neurons retrogradely labeled from the cranial meninges, we have recorded pH-evoked currents using whole-cell patch-clamp electrophysiology....

journal_title：Pain

authors： Yan J,Edelmayer RM,Wei X,De Felice M,Porreca F,Dussor G

更新日期：2011-01-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) activity in the spinal cord plays a key role in sensitization to sensory stimuli during acute inflammation. In contrast, intrathecal administration of COX-2 specific inhibitors has minimal analgesic effects in an incisional model of postoperative pain. We investigated the role of COX isoforms ...

journal_title：Pain

authors： Zhu X,Conklin D,Eisenach JC

更新日期：2003-07-01 00:00:00

abstract：:Cross-sectional research in clinical samples, as well as experimental studies in healthy adults, suggests that the experiences of pain and sleep are bi-directionally connected. However, whether sleep and pain experiences are prospectively linked to one another on a day-to-day basis in the general population has not pr...

journal_title：Pain

authors： Edwards RR,Almeida DM,Klick B,Haythornthwaite JA,Smith MT

更新日期：2008-07-01 00:00:00

abstract：:Nitric oxide (NO), synthesised by different isoforms of nitric oxide synthase (NOS), has been linked with the development and maintenance of nociception. We studied the role of the inducible isoform, iNOS, in two different rat pain models with an inflammatory component. iNOS was immunohistochemically detected locally ...

journal_title：Pain

authors： De Alba J,Clayton NM,Collins SD,Colthup P,Chessell I,Knowles RG

更新日期：2006-01-01 00:00:00

abstract：:The effects of pretreatment with desipramine, a selective noradrenaline (NA) uptake blocker, on spinal antinociception by 5-hydroxytryptamine (5-HT), morphine and an adenosine analog (NECA) in the rat hot-plate test were examined to determine if endogenous NA is involved in the spinal action of these agents. Desiprami...

journal_title：Pain

authors： Sawynok J,Reid A

更新日期：1992-07-01 00:00:00

abstract：:Two models of the relationship between paraspinal EMG and low back pain have been proposed. Specific predictions arising from these are listed and the literature relating to them reviewed. Recent research on patterns of EMG rather than absolute levels is also discussed. It is concluded that there is no consistent evid...

journal_title：Pain

authors： Nouwen A,Bush C

更新日期：1984-10-01 00:00:00