Pain-related musculoskeletal disorders, psychological comorbidity, and the relationship with physical and mental well-being in Gulf War veterans.

abstract：:Pain scales using faces are commonly used tools for assessing pain in children capable of communicating. However, some children require other types of pain scales because they have difficulties in understanding faces pain scales. The goal of this study was to develop and validate the "Pain Block" concrete ordinal scal...

journal_title：Pain

authors： Jung JH,Lee JH,Kim DK,Jung JY,Chang I,Kwon H,Shin J,Paek SH,Oh S,Kwak YH

更新日期：2018-04-01 00:00:00

abstract：:Skin conductance and heart rate measures obtained from subjects previous to, during, and after their performance of the cold pressor task were correlated with their responses to the McGill Pain Questionnaire administered immediately after the completion of the cold pressor task. A reliable relationship between skin co...

journal_title：Pain

authors： Dowling J

更新日期：1982-01-01 00:00:00

abstract：:Behavioral studies have suggested that placebo analgesia is partly mediated by the endogenous opioid system. Expanding on these results we have shown that the opioid-receptor-rich rostral anterior cingulate cortex (rACC) is activated in both placebo and opioid analgesia. However, there are also differences between the...

journal_title：Pain

authors： Petrovic P,Kalso E,Petersson KM,Andersson J,Fransson P,Ingvar M

更新日期：2010-07-01 00:00:00

abstract：:Features of somatisation have been shown to predict the onset of widespread body pain. This study aims to determine to what extent persons with orofacial pain syndromes share these features and to what extent they are uniquely related to oral mechanical factors. We have conducted a population-based cross-sectional sur...

journal_title：Pain

authors： Macfarlane TV,Blinkhorn AS,Davies RM,Ryan P,Worthington HV,Macfarlane GJ

更新日期：2002-10-01 00:00:00

abstract：:Monoclonal antibodies against GD(2) ganglioside, such as ch14.18, the human-mouse chimeric antibody, have been shown to be effective for the treatment of neuroblastoma. However, treatment is associated with generalized, relatively opiate-resistant pain. We investigated if a point mutation in ch14.18 antibody (hu14.18K...

journal_title：Pain

authors： Sorkin LS,Otto M,Baldwin WM 3rd,Vail E,Gillies SD,Handgretinger R,Barfield RC,Yu HM,Yu AL

更新日期：2010-04-01 00:00:00

abstract：:Two hundred and sixty-three ambulatory patients older than 21 years of age who were attending clinics at an oncology hospital in San Juan, Puerto Rico, were studied. They completed a questionnaire (BQ-PR) that measures 8 concerns about reporting pain and using analgesics, such as fears of addiction and tolerance and t...

journal_title：Pain

authors： Ward SE,Hernandez L

更新日期：1994-08-01 00:00:00

abstract：:Tolerance to morphine-induced analgesia is an intractable phenomenon, often hindering its prolonged applications in the clinics. The enhanced pronociceptive actions of spinal pain-related molecules such as calcitonin gene-related peptide (CGRP) may underlie this phenomenon and could be a promising target for intervent...

journal_title：Pain

authors： Wang Z,Ma W,Chabot JG,Quirion R

更新日期：2010-10-01 00:00:00

abstract：:Cultures differ as to typical linguistic reports and classifications of pain. In some languages upwards of a dozen specific pain terms are in common use, each indicating a particular pain experience. In other languages a single inclusive term is the norm, perhaps with optional qualifiers added to make desired distinct...

journal_title：Pain

authors： Diller A

更新日期：1980-08-01 00:00:00

abstract：:Back pain is a leading cause of disability. Previous research suggests that modifiable risk factors influence recovery from back pain, and practice guidelines recommend integrating such factors within primary care management. Toward this goal, a brief, multidimensional questionnaire, the STarT Back Tool, was designed ...

journal_title：Pain

authors： Wideman TH,Hill JC,Main CJ,Lewis M,Sullivan MJL,Hay EM

更新日期：2012-11-01 00:00:00

abstract：:Spinal synaptic plasticity is believed to drive central sensitization that underlies the persistent nature of neuropathic pain. Our recent data showed that synaptic plasticity in the dorsal horn is cell type specific: intense afferent stimulation produced long-term potentiation (LTP) in excitatory spinothalamic tract ...

journal_title：Pain

authors： Bittar A,Jun J,La JH,Wang J,Leem JW,Chung JM

更新日期：2017-11-01 00:00:00

abstract：:We investigated the effects of acute and of chronic morphine treatment on T-lymphocyte function and natural killer (NK) cell activity in rats receiving chronic constriction injury (CCI) of the sciatic nerve. T-Lymphocyte function was evaluated based on concanavalin-A (ConA)- and phytohemagglutinin (PHA)-induced spleno...

journal_title：Pain

authors： Tsai YC,Won SJ,Lin MT

更新日期：2000-11-01 00:00:00

abstract：:The National Institutes of Health released the trial registry ClinicalTrials.gov in 2000 to increase public reporting and clinical trial transparency. This systematic review examined whether registered primary outcome specifications (POS; ie, definitions, timing, and analytic plans) in analgesic treatment trials corre...

journal_title：Pain

authors： Smith SM,Wang AT,Pereira A,Chang DR,McKeown A,Greene K,Rowbotham MC,Burke LB,Coplan P,Gilron I,Hertz SH,Katz NP,Lin AH,McDermott MP,Papadopoulos EJ,Rappaport BA,Sweeney M,Turk DC,Dworkin RH

更新日期：2013-12-01 00:00:00

abstract：:Two classes of neurons with distinct responses to opioids have been identified in the rostral ventromedial medulla (RVM), a region with a well-documented role in nociceptive modulation. 'On-cells' are directly inhibited by opioids, and opioids can thus gain access to the modulatory circuitry of the RVM by an action on...

journal_title：Pain

authors： Heinricher MM,McGaraughty S

更新日期：1998-04-01 00:00:00

abstract：:We evaluated the construct validity (including responsiveness), reliability, and feasibility of the Pain Squad multidimensional smartphone-based pain assessment application (app) in children and adolescents with cancer, using 2 descriptive studies with repeated measures. Participants (8-18 years) undergoing cancer tre...

journal_title：Pain

authors： Stinson JN,Jibb LA,Nguyen C,Nathan PC,Maloney AM,Dupuis LL,Gerstle JT,Hopyan S,Alman BA,Strahlendorf C,Portwine C,Johnston DL

更新日期：2015-12-01 00:00:00

abstract：:Serotonin is critically involved in neuropathic pain. However, its role is far from being understood owing to the number of cellular targets and receptor subtypes involved. In a rat model of neuropathic pain evoked by chronic constriction injury (CCI) of the sciatic nerve, we studied the role of 5-HT(2B) receptor in d...

journal_title：Pain

authors： Urtikova N,Berson N,Van Steenwinckel J,Doly S,Truchetto J,Maroteaux L,Pohl M,Conrath M

更新日期：2012-06-01 00:00:00

abstract：:Past research has shown that pain catastrophizing contributes to heightened pain experience. The hypothesis advanced in this study was that individuals who score high on measures of pain catastrophizing would also perceive more intense pain in others. The study also examined the role of pain behaviour as a determinant...

journal_title：Pain

authors： Sullivan MJ,Martel MO,Tripp DA,Savard A,Crombez G

更新日期：2006-07-01 00:00:00

abstract：:Extracellular adenosine triphosphate (ATP), acting at P2X ionotropic receptors, is implicated in numerous sensory processes. Exogenous ATP has been shown to be algogenic in both animals and humans. Research focus has been directed towards the P2X(3) receptor, as it is preferentially expressed on nociceptive C-fibers a...

journal_title：Pain

authors： Honore P,Kage K,Mikusa J,Watt AT,Johnston JF,Wyatt JR,Faltynek CR,Jarvis MF,Lynch K

更新日期：2002-09-01 00:00:00

abstract：:Sex differences for chronic back pain (cBP) have been reported, with females usually exhibiting greater morbidity, severity, and poorer response to treatment. Genetic factors acting in an age-specific manner have been implicated but never comprehensively explored. We performed sex- and age-stratified genome-wide assoc...

journal_title：Pain

authors： Freidin MB,Tsepilov YA,Stanaway IB,Meng W,Hayward C,Smith BH,Khoury S,Parisien M,Bortsov A,Diatchenko L,Børte S,Winsvold BS,Brumpton BM,Zwart JA,Aulchenko YS,Suri P,Williams FMK,HUNT All-In Pain.

更新日期：2020-09-30 00:00:00

abstract：:Neuropathic pain may be effectively relieved by electric stimulation of the spinal cord (SCS). However, the underlying mechanisms for the ensuing pain relief are poorly understood. In a rat model of neuropathy displaying hypersensitivity to innocuous tactile stimuli, (allodynia), we have earlier demonstrated that SCS ...

journal_title：Pain

authors： Cui JG,O'Connor WT,Ungerstedt U,Linderoth B,Meyerson BA

更新日期：1997-10-01 00:00:00

abstract：:This study determined preoperative predictors of movement and resting pain following total knee replacement (TKR). We hypothesized that younger patients with higher preoperative pain intensity, pain sensitivity, trait anxiety, pain catastrophizing, and depression would be more likely to experience higher postoperative...

journal_title：Pain

authors： Rakel BA,Blodgett NP,Zimmerman BM,Logsden-Sackett N,Clark C,Noiseux N,Callaghan J,Herr K,Geasland K,Yang X,Sluka KA

更新日期：2012-11-01 00:00:00

abstract：:Neuropathic pain behaviour is not observed in neonatal rats and tactile allodynia does not develop in the spared nerve injury (SNI) model until rats are 4 weeks of age at the time of surgery. Since activated spinal microglia are known to play a key role in neuropathic pain, we have investigated whether the microglial ...

journal_title：Pain

authors： Moss A,Beggs S,Vega-Avelaira D,Costigan M,Hathway GJ,Salter MW,Fitzgerald M

更新日期：2007-04-01 00:00:00

abstract：:Behavioral analgesic techniques such as distraction reduce pain in both clinical and experimental settings. Individuals differ in the magnitude of distraction-induced analgesia, and additional study is needed to identify the factors that influence the pain relieving effects of distraction. Catastrophizing, a set of ne...

journal_title：Pain

authors： Campbell CM,Witmer K,Simango M,Carteret A,Loggia ML,Campbell JN,Haythornthwaite JA,Edwards RR

更新日期：2010-05-01 00:00:00

abstract：:While a variety of cultural, psychological and physiological factors contribute to variability in both clinical and experimental contexts, the role of genetic factors in human pain sensitivity is increasingly recognized as an important element. This study was performed to evaluate genetic influences on variability in ...

journal_title：Pain

authors： Kim H,Neubert JK,San Miguel A,Xu K,Krishnaraju RK,Iadarola MJ,Goldman D,Dionne RA

更新日期：2004-06-01 00:00:00

abstract：:Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the body. It has been suggested that such side bias results from corti...

journal_title：Pain

authors： Leite-Almeida H,Cerqueira JJ,Wei H,Ribeiro-Costa N,Anjos-Martins H,Sousa N,Pertovaara A,Almeida A

更新日期：2012-11-01 00:00:00

abstract：:The antinociceptive effects of the serotonin (5-HT)1A/7 receptor agonist 8-hydroxy-dipropylaminotetralin (8-OH-DPAT) administered into the medial thalamus were evaluated. Pain behaviors organized at spinal (spinal motor reflexes, SMRs), medullary (vocalizations during shock, VDSs), and forebrain (vocalization after di...

journal_title：Pain

authors： Harte SE,Kender RG,Borszcz GS

更新日期：2005-02-01 00:00:00

abstract：:We know little about the safety or efficacy of pharmacological medicines for children and adolescents with chronic pain, despite their common use. Our aim was to conduct an overview review of systematic reviews of pharmacological interventions that purport to reduce pain in children with chronic noncancer pain (CNCP) ...

journal_title：Pain

authors： Eccleston C,Fisher E,Cooper TE,Grégoire MC,Heathcote LC,Krane E,Lord SM,Sethna NF,Anderson AK,Anderson B,Clinch J,Gray AL,Gold JI,Howard RF,Ljungman G,Moore RA,Schechter N,Wiffen PJ,Wilkinson NMR,Williams DG,Wood

更新日期：2019-08-01 00:00:00

abstract：:The present study investigated the role of micro, delta, and kappa receptors within the RVM in mediating expression of conditional hypoalgesia (CHA). Five groups of rats with RVM cannulae were given daily sessions of paired or unpaired presentations of an auditory CS (white noise) and foot shock across three consecuti...

journal_title：Pain

authors： Foo H,Helmstetter FJ

更新日期：1999-12-01 00:00:00

abstract：:The purpose of this study was to examine racial/ethnic-related differences in a four-stage model of the processing of chronic pain. The subjects were 1557 chronic pain patients (White=1084, African American=473) evaluated at a pain management clinic at a large southeastern university medical center. Using an analysis ...

journal_title：Pain

authors： Riley JL 3rd,Wade JB,Myers CD,Sheffield D,Papas RK,Price DD

更新日期：2002-12-01 00:00:00

abstract：:Endometriosis, an estrogen-dependent chronic inflammatory disease, is the most common cause of chronic pelvic pain. Here, we investigated the effects of linaclotide, a Food and Drug Administration-approved treatment for IBS-C, in a rat model of endometriosis. Eight weeks after endometrium transplantation into the inte...

journal_title：Pain

authors： Ge P,Ren J,Harrington AM,Grundy L,Castro J,Brierley SM,Hannig G

更新日期：2019-11-01 00:00:00

abstract：:Omega-3 and n-6 fatty acids are biosynthetic precursors to lipid mediators with antinociceptive and pronociceptive properties. We conducted a randomized, single-blinded, parallel-group clinical trial to assess clinical and biochemical effects of targeted alteration in dietary n-3 and n-6 fatty acids for treatment of c...

journal_title：Pain

authors： Ramsden CE,Faurot KR,Zamora D,Suchindran CM,MacIntosh BA,Gaylord S,Ringel A,Hibbeln JR,Feldstein AE,Mori TA,Barden A,Lynch C,Coble R,Mas E,Palsson O,Barrow DA,Mann DJ

更新日期：2013-11-01 00:00:00