Racial/ethnic differences in the experience of chronic pain.

abstract：:Our previous studies in the Sprague-Dawley rat showed that the intrinsic antinociceptive effects of oxycodone are naloxone reversible in a manner analogous to morphine but that in contrast to morphine, oxycodone's antinociceptive effects have a rapid onset of maximum effect (approximately 5-7 min compared to 30-45 min...

journal_title：Pain

authors： Ross FB,Smith MT

更新日期：1997-11-01 00:00:00

abstract：:A secondary zone of cutaneous hyperalgesia in humans is characterized by increased pain to mechanical stimuli. In contrast, the perception of heat stimuli delivered to a secondary zone of hyperalgesia in humans often shows a paradoxical decrease in magnitude. A number of studies have shown that the responses of spinal...

journal_title：Pain

authors： Dougherty MP,Willis DW,Lenz AF

更新日期：1998-08-01 00:00:00

abstract：:Bradykinin is an endogenous peptide that is thought to be a chemical mediator of the hyperalgesia following inflammation. In rat, bradykinin has been postulated to cause hyperalgesia to mechanical stimuli by releasing prostaglandin from sympathetic post-ganglionic terminals. The aim of this study was to determine whet...

journal_title：Pain

authors： Meyer RA,Davis KD,Raja SN,Campbell JN

更新日期：1992-12-01 00:00:00

abstract：:The associative network theory of memory [2] is outlined along with the concepts of mood congruity and state dependent learning. Two experiments are reported which investigate the occurrence of these effects where memory for pain is concerned. In experiment 1 the performance of 25 chronic pain patients was compared wi...

journal_title：Pain

authors： Pearce SA,Isherwood S,Hrouda D,Richardson PH,Erskine A,Skinner J

更新日期：1990-11-01 00:00:00

abstract：:OnabotulinumtoxinA (onabotA) has shown efficacy in chronic migraine (CM). Its mechanism of action, however, remains obscure. We have analysed whether treatment with onabotA is able to induce changes in interictal plasma calcitonin gene-related peptide (CGRP) concentrations, which have been shown to be increased in pat...

journal_title：Pain

authors： Cernuda-Morollón E,Ramón C,Martínez-Camblor P,Serrano-Pertierra E,Larrosa D,Pascual J

更新日期：2015-05-01 00:00:00

abstract：:Extracellular signal-regulated kinase (ERK), a mitogen-activated protein kinases (MAPK), transduces a broad range of extracellular stimuli into diverse intracellular responses. Recent studies have showed that ERK activation in the supraspinal level involved in the development of drug dependence, especially in psycholo...

journal_title：Pain

authors： Cao JL,He JH,Ding HL,Zeng YM

更新日期：2005-12-05 00:00:00

abstract：:Pain evoked potentials (EPs) have been used in the last two decades as means of obtaining objective measures of pain, in clinical and experimental setups. The possibility that the pain EP wave contains elements of the endogenous P300 potential rather than being a neurophysiological correlate of pain has been raised by...

journal_title：Pain

authors： Zaslansky R,Sprecher E,Tenke EC,Hemli AJ,Yarnitsky D

更新日期：1996-07-01 00:00:00

abstract：:The effects of intrathecal administration of substance P and N-methyl-D-aspartate (NMDA) were studied in the formalin test in mice. Both substances were administered 5 min before injection of formalin into the hind paw. Co-administration of substance P and NMDA intensified the response in both the 1st (0-10 min) and t...

journal_title：Pain

authors： Mjellem-Joly N,Lund A,Berge OG,Hole K

更新日期：1992-11-01 00:00:00

abstract：:Migraine headache is one of the most common neurological disorders. The pathological conditions that directly initiate afferent pain signaling are poorly understood. In trigeminal neurons retrogradely labeled from the cranial meninges, we have recorded pH-evoked currents using whole-cell patch-clamp electrophysiology....

journal_title：Pain

authors： Yan J,Edelmayer RM,Wei X,De Felice M,Porreca F,Dussor G

更新日期：2011-01-01 00:00:00

abstract：:Changes in perception of pure thermal stimuli delivered to the hand at threshold intensity were observed during ischemic nerve block in 27 healthy subjects in order to study the significance of unmyelinated cutaneous cold receptors for thermal sensibility. Paresthesias and an increasing feeling of numbness were follow...

journal_title：Pain

authors： Fruhstorfer H

更新日期：1984-12-01 00:00:00

abstract：:Two cases of reflex sympathetic dystrophy in the upper extremity of patients with traumatic cervical spinal cord injuries are reported. Both patients had very incomplete lesions with early neurological recovery, suggesting an underlying central cord syndrome. Although reflex sympathetic dystrophy is often seen followi...

journal_title：Pain

authors： Wainapel SF

更新日期：1984-04-01 00:00:00

abstract：:Neuropathic pain behaviour is not observed in neonatal rats and tactile allodynia does not develop in the spared nerve injury (SNI) model until rats are 4 weeks of age at the time of surgery. Since activated spinal microglia are known to play a key role in neuropathic pain, we have investigated whether the microglial ...

journal_title：Pain

authors： Moss A,Beggs S,Vega-Avelaira D,Costigan M,Hathway GJ,Salter MW,Fitzgerald M

更新日期：2007-04-01 00:00:00

abstract：:The presence of a trigger point is essential to the myofascial pain syndrome. This study centres on identifying clearer criteria for the presence of trigger points in the quadratus lumborum and gluteus medius muscle by investigating the occurrence and inter-rater reliability of trigger point symptoms. Using the sympto...

journal_title：Pain

authors： Hua NK,Van der Does E

更新日期：1994-09-01 00:00:00

abstract：:In the last decade, there has been burgeoning interest in the effectiveness of third-generation psychological therapies for managing fibromyalgia (FM) symptoms. The present study examined the effectiveness of acceptance and commitment therapy (ACT) on functional status as well as the role of pain acceptance as a media...

journal_title：Pain

authors： Luciano JV,Guallar JA,Aguado J,López-Del-Hoyo Y,Olivan B,Magallón R,Alda M,Serrano-Blanco A,Gili M,Garcia-Campayo J

更新日期：2014-04-01 00:00:00

abstract：:Nociceptive impulse activity was recorded extracellularly from single A delta and C primary afferents of the guinea pig's medial articular nerve after induction of an experimental osteoarthritis in the knee joint by partial medial menisectomy and transection of the anterior cruciate ligament (PMM+TACL). Also, the anal...

journal_title：Pain

authors： Gomis A,Miralles A,Schmidt RF,Belmonte C

更新日期：2007-07-01 00:00:00

abstract：:The present study observed the expression of the 5-hydroxytryptamine (5-HT) (1A) receptor mRNA in the lumbar spinal dorsal horn neurons following carrageenan inflammation using in situ hybridization (ISH). We also studied the co-localization of 5-HT(1A) receptor mRNA and gamma-amino butyric acid (GABA) or enkephalin (...

journal_title：Pain

authors： Zhang YQ,Gao X,Ji GC,Huang YL,Wu GC,Zhao ZQ

更新日期：2002-08-01 00:00:00

abstract：:Changes in pain produced by psychological factors (e.g., placebo analgesia) are thought to result from the activity of specific cortical regions. However, subcortical nuclei, including the periaqueductal gray and the rostroventral medulla, also show selective activation when subjects expect pain relief. These brainste...

journal_title：Pain

authors： Goffaux P,Redmond WJ,Rainville P,Marchand S

更新日期：2007-07-01 00:00:00

abstract：:A preliminary report of clinical study revealed that chronic discogenic low back pain could be treated by intradiscal methylene blue (MB) injection. We investigated the effect of intradiscal MB injection for the treatment of chronic discogenic low back pain in a randomized placebo-controlled trial. We recruited 136 pa...

journal_title：Pain

authors： Peng B,Pang X,Wu Y,Zhao C,Song X

更新日期：2010-04-01 00:00:00

abstract：:This preliminary study examined the self-efficacy of family caregivers with regard to helping cancer patients manage pain at end of life. A sample of 63 family caregivers of hospice-eligible cancer patients with pain provided ratings of their self-efficacy in assisting the patient in pain management and rated their ow...

journal_title：Pain

authors： Keefe FJ,Ahles TA,Porter LS,Sutton LM,McBride CM,Pope MS,McKinstry ET,Furstenberg CP,Dalton J,Baucom DH

更新日期：2003-05-01 00:00:00

abstract：:Below-level central neuropathic pain (CNP) affects a large proportion of spinal cord injured individuals. To better define the dynamic changes of the spinal cord neural network contributing to the development of CNP after spinal cord injury (SCI), we characterized the morphological and behavioral correlates of CNP in ...

journal_title：Pain

authors： Nees TA,Tappe-Theodor A,Sliwinski C,Motsch M,Rupp R,Kuner R,Weidner N,Blesch A

更新日期：2016-03-01 00:00:00

abstract：:Fifty adult patients with chronic pain and substance dependence were admitted to an inpatient unit for treatment of addiction without primary emphasis on treatment of pain. As a group they had received considerable medical attention for their pain, but relatively little for their addictions. When compared with a group...

journal_title：Pain

authors： Finlayson RE,Maruta T,Morse RM,Swenson WM,Martin MA

更新日期：1986-08-01 00:00:00

abstract：:The use of long-term opioid therapy for chronic pain remains common, yet data on long-term outcomes, especially after dose escalation, are sparse. This study examined potential benefits and harms associated with prescription opioid dose escalation. Participants from 2 institutions were enrolled in a 2-year prospective...

journal_title：Pain

authors： Morasco BJ,Smith N,Dobscha SK,Deyo RA,Hyde S,Yarborough BJH

更新日期：2020-06-01 00:00:00

abstract：:Abnormal endogenous pain modulation was suggested as a potential mechanism for chronic pain, ie, increased pain facilitation and/or impaired pain inhibition underlying symptoms manifestation. Endogenous pain modulation function can be tested using psychophysical methods such as temporal summation of pain (TSP) and con...

journal_title：Pain

authors： Moana-Filho EJ,Herrero Babiloni A,Theis-Mahon NR

更新日期：2018-08-01 00:00:00

abstract：:Tricyclic antidepressants (TCAs) have been found to be useful in the management of a variety of chronic pain conditions, although there is little published regarding the potential efficacy of this class of drug as an adjunct for the control of acute postoperative pain and related symptoms. Twenty-eight patients underg...

journal_title：Pain

authors： Kerrick JM,Fine PG,Lipman AG,Love G

更新日期：1993-03-01 00:00:00

abstract：:Chronic pain is associated with large societal costs, but few studies have investigated the total costs of chronic pain with respect to elderly subjects. The elderly usually require informal care, care performed by municipalities, and care for chronic diseases, all factors that can result in extensive financial burden...

journal_title：Pain

authors： Bernfort L,Gerdle B,Rahmqvist M,Husberg M,Levin LÅ

更新日期：2015-03-01 00:00:00

abstract：:To address the lack of appropriate patient-defined quality indicators (QIs) for assessment of pain clinic care in the Netherlands, we developed the "Quality Indicators Pain Patients' Perspective" (QiPPP) questionnaire. Quality indicators are widely used to measure the quality of the structure, process, and outcome of ...

journal_title：Pain

authors： de Meij N,Köke A,Thomassen I,Kallewaard JW,van Kleef M,van der Weijden T

更新日期：2018-12-01 00:00:00

abstract：:Ten healthy subjects (four male) of mean age 31 years (range 25-40) took part in a randomized double-blind four-way crossover study to examine the cognitive and psychomotor effects of repeated oral doses of dextropropoxyphene and morphine. Four treatments were compared: dextropropoxyphene napsylate 100 mg, morphine su...

journal_title：Pain

authors： O'Neill WM,Hanks GW,Simpson P,Fallon MT,Jenkins E,Wesnes K

更新日期：2000-03-01 00:00:00

abstract：:Thirty subjects were given a placebo (intravenous saline), which was described as a known pain killer, once a week for 3 consecutive weeks. Experimental ischemic arm pain was produced prior to the placebo and again 1 h later. In a double blind procedure, half of the subjects received 10 mg of naloxone after placebo; t...

journal_title：Pain

authors： Grevert P,Albert LH,Goldstein A

更新日期：1983-06-01 00:00:00

abstract：:The present study examined the relationship between depression and a constellation of pain-related variables that describe the experience of chronic pain patients. Thirty-seven depressed and 32 non-depressed heterogeneous chronic pain patients were identified through structured interviews, use of standardized criteria...

journal_title：Pain

authors： Haythornthwaite JA,Sieber WJ,Kerns RD

更新日期：1991-08-01 00:00:00

abstract：:The purpose of this study was to determine if some commonly used admission variables could predict treatment outcome on a multidisciplinary pain center. Specifically, it was designed as a prospective study of an index proposed by Maruta et al. The subjects were 104 patients. The 4 outcome measures used were staff judg...

journal_title：Pain

authors： Aronoff GM,Evans WO

更新日期：1982-09-01 00:00:00