Abstract：
:This study reports a 9-18 month follow-up of a randomised controlled trial of pain management programmes for chronic, non-malignant pain. Twenty-two inpatients, 18 outpatients and 12 control subjects completed the follow-up assessments. Significant treatment effects were demonstrated by the inpatient group on pain ratings, the Pain Behaviour Checklist, and General Health Questionnaire, with similar effects demonstrated by the outpatient group on the former 2 measures. The findings were confounded by higher inpatient scores at pretreatment, in comparison with the 2 other conditions. There was a high drop-out rate of subjects, particularly from the control condition which illustrates the limitations of controlled group designs in this area. Analgesic use, activity levels and pain ratings were also evaluated using the criteria for 'success' described by Malec et al. (1981). Results indicated that 68% of inpatients, 61% of outpatients and 21% of control subjects met all 3 criteria. Both treatment programmes were effective in returning patients to paid employment, whilst 3 control group patients gave up work. The cost-benefit implications of these changes are discussed. We conclude that pain management programmes contribute substantially to the rehabilitation of chronic pain sufferers.
journal_name
Painjournal_title
Painauthors
Peters J,G Large R,Elkind Gdoi
10.1016/0304-3959(92)90110-Wkeywords:
subject
Has Abstractpub_date
1992-07-01 00:00:00pages
41-50issue
1eissn
0304-3959issn
1872-6623pii
00006396-199207000-00006journal_volume
50pub_type
临床试验,杂志文章,随机对照试验相关文献
PAIN文献大全abstract：:Pain and thermal sensitivity thresholds in healthy volunteers were examined for diurnal variations. The subjects were 11 men aged between 22 and 27 years (means = 23.5, S.D. = 1.5). Data were collected for 2 days, with 7 measurements per day. To ensure the pain specificity of the results the subliminal modality, i.e.,...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90120-6
更新日期：1989-01-01 00:00:00
abstract：:Although the administration of opioids is the most effective treatment for pain, their efficacy is limited by the development of tolerance. The midbrain periaqueductal gray matter (PAG) participates in opioid analgesia and tolerance. Microinjection of morphine into PAG produces antinociception, probably through neuron...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(00)00367-5
更新日期：2001-01-01 00:00:00
abstract：:This study compared a remote-delivered pain management program, the Pain Course, when delivered in online and workbook formats. Participants (n = 178) were randomised into 2 groups: (1) an Internet Group (n = 84) who were provided with secure accounts to the program in an online format; or (2) a Workbook Group (n = 94...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1097/j.pain.0000000000000916
更新日期：2017-07-01 00:00:00
abstract：:The present study observed the expression of the 5-hydroxytryptamine (5-HT) (1A) receptor mRNA in the lumbar spinal dorsal horn neurons following carrageenan inflammation using in situ hybridization (ISH). We also studied the co-localization of 5-HT(1A) receptor mRNA and gamma-amino butyric acid (GABA) or enkephalin (...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(02)00026-X
更新日期：2002-08-01 00:00:00
abstract：:There is evidence that serotonin may be implicated in the pathophysiology of myofascial pain (MFP). Because of this, we used oral sumatriptan (Imitrex, Glaxo), a peripherally acting agonist of 5-HT1D receptors, in a double-blind, randomized, placebo-controlled double crossover pilot study of 7 patients with episodic M...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(95)00025-N
更新日期：1995-08-01 00:00:00
abstract：:Altogether 553 children (195 first graders, mean age 6.8 years, and 358 third graders, mean age 8.7 years) participated in the development of a self-report measure to assess the intensity of children's pain. The first step was the derivation, from children's drawings of facial expressions of pain, of 5 sets of 7 schem...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(90)90018-9
更新日期：1990-05-01 00:00:00
abstract：:Inflammation enhances release of neuropeptides from sensory nerve terminals in the spinal cord, and this may contribute to the development of hyperalgesia. In a similar manner, proinflammatory prostaglandins also augment peptide release from sensory neurons. To ascertain whether the inflammation-induced increase in pe...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(98)00113-4
更新日期：1998-10-01 00:00:00
abstract：:The aims of this study were threefold. Firstly, to investigate the effect of increasing threat-expectancy on attentional biases towards pain-related words. Secondly, to determine the interaction between threat-expectancy and the effectiveness of two coping strategies on pain threshold and tolerance. Thirdly, to invest...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2005.09.032
更新日期：2005-12-15 00:00:00
abstract：:Tricyclic antidepressants (TCAs) have been found to be useful in the management of a variety of chronic pain conditions, although there is little published regarding the potential efficacy of this class of drug as an adjunct for the control of acute postoperative pain and related symptoms. Twenty-eight patients underg...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(93)90166-M
更新日期：1993-03-01 00:00:00
abstract：:This study investigated the effects of a single administration of 6-(4-methoxyphenyl)-5-methyl-3-pyridinyl-4-isoxazolo[4,5-c]pyridin-4(5H)-one (MMPIP), a negative allosteric modulator (NAM) of metabotropic glutamate receptor 7 (mGluR7), on pain and on affective and cognitive behavior in neuropathic mice. The activity ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000000150
更新日期：2015-06-01 00:00:00
abstract：:No research to date has descriptively catalogued what parents of healthy infants are naturalistically doing to manage their infant's pain over immunization appointments during the first year of life. This knowledge, in conjunction with an understanding of the relationships different parental techniques have with infan...
journal_title：Pain
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pain.2013.03.036
更新日期：2013-08-01 00:00:00
abstract：:To investigate the pathways of noxious information in the spinal cord in humans, we recorded cortical potentials following the stimulation of A-delta fibers using a YAG laser applied to two cutaneous points on the back at the C7 and Th10 level, 4cm to the right of the vertebral spinous process. A multiple source analy...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.03.009
更新日期：2006-08-01 00:00:00
abstract：:Previous evidence supports the utility of the newly developed pain attitudes questionnaire (PAQ) for assessing pain-related stoicism and cautiousness in community-dwelling pain-free adults (Yong et al., 2001). A revised questionnaire (PAQ-R) was examined in the present study to determine the generalizability of psycho...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(03)00140-4
更新日期：2003-08-01 00:00:00
abstract：:Our aim was to assess the discriminative capacity of the McGill Pain Questionnaire (MPQ) in patients with temporomandibular joint (TMJ) disorders or with myogenous facial pain (MP). The MPQ was administered to 57 TMJ and 28 MP patients who were also asked to assess the level of pain using the Visual Analog Scale (VAS)...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(00)00461-9
更新日期：2001-04-01 00:00:00
abstract：:Self-hypnosis was taught to 5 highly hypnotisable patients referred to Auckland Hospital Pain Clinic. Evaluation included the Illness Self-Concept Repertory Grid (ISCRG) and follow-up was at 1 and 6 months post treatment. Consensus grids indicated the subjects initially identified with physical illness but this associ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90223-0
更新日期：1988-11-01 00:00:00
abstract：:The aim of this study was to investigate how exercise influenced endogenous pain modulation in healthy controls, shoulder myalgia patients and fibromyalgia (FM) patients. Twenty-one healthy subjects, 20 shoulder myalgia patients and 20 FM patients, all females, participated. They performed standardized static contract...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2010.06.021
更新日期：2010-10-01 00:00:00
abstract：:Do contrasting neuropathic pain diagnoses share common pathophysiological mechanisms? Selective breeding was used to derive rat lines with a common genetic background but a striking difference in the degree of spontaneous pain behavior expressed in the neuroma model of neuropathic pain (HA rats (high autotomy) and LA ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.07.020
更新日期：2009-11-01 00:00:00
abstract：:Fibromyalgia (FM) is a prevalent and disabling chronic disease. Recent studies have found elevated levels of glutamate in several brain regions, leading to hypotheses about the usefulness of glutamate-blocking drugs such as memantine in the treatment of FM. The aim of this study was to evaluate the efficacy of memanti...
journal_title：Pain
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.pain.2014.09.004
更新日期：2014-12-01 00:00:00
abstract：:The purpose of this study was to examine the relationship between a mother's rating of her own and her child's anxiety and their observed behavior during an immunization. Eighty-three preschool children and their mothers were observed in a health screening clinic while the child received an immunization. Each mother w...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90156-5
更新日期：1989-04-01 00:00:00
abstract：:Chronic pain was induced in rats by daily injections of complete Freund's adjuvant into hind paws. Daily changes of pain threshold and endorphin (ED) content and their receptors in 4 divided parts: cortex, diencephalon-mesencephalon containing striatum (D-M), pons-medulla (P-M) and spinal cord, were measured. Decrease...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(83)90131-8
更新日期：1983-09-01 00:00:00
abstract：:In the present study, we evaluated the relationship between hypertension and the antinociceptive effect of clonidine in genetically hypertensive rats. Intraperitoneal (i.p.) administration of clonidine (0.69 mg/kg) produced hypoalgesia without lowering blood pressure in conscious spontaneously hypertensive (SH), spont...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(93)90055-T
更新日期：1993-04-01 00:00:00
abstract：:Sendide is a selective and extremely potent antagonist of neurokinin-1 (NK1) receptors in the mouse spinal cord. The antinociceptive activities of sendide, an antagonist of NK1 receptors, and its analogue, [D-Trp7]sendide have been examined after intrathecal (i.t.) administrations in the mouse paw formalin test. Intra...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(94)00107-P
更新日期：1995-02-01 00:00:00
abstract：:The effect of PF-04457845, a potent and selective fatty acid amide hydrolase-1 (FAAH1) inhibitor, on pain due to osteoarthritis of the knee was investigated in a randomised placebo and active-controlled clinical trial. The trial involved 2 periods (separated by a 2-week washout) consisting of a 1-week wash-in phase fo...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2012.04.020
更新日期：2012-09-01 00:00:00
abstract：:Histamine, substance P, serotonin and bradykinin were applied by iontophoresis to lesional and visually non-lesional skin of 14 patients with atopic dermatitis, and normal skin of 15 healthy volunteers. Itch could be evoked by light stroking of skin with a cotton swab (alloknesis) in all lesional skin sites, but not i...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.06.003
更新日期：2006-12-15 00:00:00
abstract：:An electrophysiological study was carried out in anesthetized rats to characterize the properties of single neurons in trigeminal (V) subnucleus caudalis. Each neuron was functionally classified in terms of its cutaneous mechanoreceptive field properties as low-threshold mechanoreceptive (LTM), wide dynamic range (WDR...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(90)90010-B
更新日期：1990-06-01 00:00:00
abstract：:An indentical questionnaire are administered separately to 100 chronic pain patients and a close family member of each. The majority of patients and relatives agreed on the answers to these questions about the pain problem. Highest congruency between patient and relative was associated with cases in which there were m...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90003-6
更新日期：1980-04-01 00:00:00
abstract：:Formalin injection into the hindpaw of rats produces many neurons with c-fos protein-like immunoreactivity (fos-neurons) in the medial 3/4 of the ipsilateral dorsal horn laminae I and II at the junction of 4th and 5th lumbar segments (the sciatic territory). The tibial nerve transection 2 or 3 days earlier resulted in...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00014-J
更新日期：1995-10-01 00:00:00
abstract：:This was a multicenter, double-blind (DB), placebo-controlled, randomized discontinuation trial to evaluate the efficacy of pregabalin monotherapy for durability of effect on fibromyalgia (FM) pain. The trial included a 6-week open-label (OL) pregabalin-treatment period followed by 26-week DB treatment with placebo or...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2008.02.027
更新日期：2008-06-01 00:00:00
abstract：:Intrusive pain is likely to have a serious impact on older people with limited ability to respond to additional stressors. Frailty is conceptualised as a functional and biological pattern of decline accumulating across multiple physiological systems, resulting in a decreased capacity to respond to additional stressors...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2008.08.011
更新日期：2008-11-15 00:00:00
abstract：:Movement is changed in pain, but the mechanisms remain unclear. Key questions are unresolved such as whether activation can be inhomogeneously distributed within a muscle in a manner that is specific to the location of noxious input. This study addressed this question using high-density electromyography (EMG) to study...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001317
更新日期：2018-11-01 00:00:00
