Systematic evaluation of commercially available pain management apps examining behavior change techniques.

abstract：:Disabling neuropathic pain (NeuP) is a common sequel of diabetic peripheral neuropathy (DPN). We aimed to characterise the sensory phenotype of patients with and without NeuP, assess screening tools for NeuP, and relate DPN severity to NeuP. The Pain in Neuropathy Study (PiNS) is an observational cross-sectional multi...

journal_title：Pain

authors： Themistocleous AC,Ramirez JD,Shillo PR,Lees JG,Selvarajah D,Orengo C,Tesfaye S,Rice ASC,Bennett DLH

更新日期：2016-05-01 00:00:00

abstract：:Inflammation enhances release of neuropeptides from sensory nerve terminals in the spinal cord, and this may contribute to the development of hyperalgesia. In a similar manner, proinflammatory prostaglandins also augment peptide release from sensory neurons. To ascertain whether the inflammation-induced increase in pe...

journal_title：Pain

authors： Southall DM,Michael LR,Vasko RM

更新日期：1998-10-01 00:00:00

abstract：:Cannabinoids are emerging as potential options for neuropathic pain treatment. This study evaluated an oral cannabinoid, nabilone, in the treatment of refractory human diabetic peripheral neuropathic pain (DPN). We performed a single-center, randomized, double-blind, placebo-controlled, flexible-dose study with an enr...

journal_title：Pain

authors： Toth C,Mawani S,Brady S,Chan C,Liu C,Mehina E,Garven A,Bestard J,Korngut L

更新日期：2012-10-01 00:00:00

abstract：:The efficacy of intravenous acetaminophen (1000mg) in the treatment of acute migraine attacks as an alternative to parenteral application of lysine acetylsalicylate or triptans was investigated, using a multi-center, randomized, double-blind, placebo controlled study design. Migraine diagnosis was made according to th...

journal_title：Pain

authors： Leinisch E,Evers S,Kaempfe N,Kraemer C,Sostak P,Jürgens T,Straube A,May A

更新日期：2005-10-01 00:00:00

abstract：:Injection of bee venom into one hindpaw of rat can elicit acute inflammation together with spontaneous pain, heat hyperalgesia and mechanical hyperalgesia/allodynia in the injected paw. 5-hydroxytryptamine (5-HT)1A receptor is the predominant receptor subtype in the spinal dorsal horn mediating the function of 5-HT in...

journal_title：Pain

authors： Wang W,Wu SX,Wang YY,Liu XY,Li YQ

更新日期：2003-11-01 00:00:00

abstract：:Psychologic assessment and treatment of the family of the chronic pain patient has been thought to be of benefit in the outcome of pain therapy. The present study was designed to determine the presence of psychologic symptoms in the spouses of pain patients and the relationship of distress levels between the marital p...

journal_title：Pain

authors： Shanfield SB,Heiman EM,Cope N,Jones JR

更新日期：1979-12-01 00:00:00

abstract：:Twenty patients with chronic low back pain received 12 lumbar sympathetic injections, in a series of 6 with bupivacaine and a series of 6 with saline. Changes in subjective pain intensity, EMG from paravertebral muscles, joint ranges of mobility, and daily activity levels were measured at multiple intervals throughout...

journal_title：Pain

authors： Brena SF,Wolf SL,Chapman SL,Hammonds WD

更新日期：1980-02-01 00:00:00

abstract：:The M-current has been proposed as a potential target for analgesia under neuropathic pain conditions. M-currents and/or their molecular correlates, KCNQ proteins, have been demonstrated in key elements of the nociceptive system including spinal and dorsal root ganglion neurons. Here we demonstrate that retigabine, a ...

journal_title：Pain

authors： Roza C,Lopez-Garcia JA

更新日期：2008-09-15 00:00:00

abstract：:This laboratory-based study examined lagged associations between child pain behavior and maternal responses as a function of maternal catastrophizing (CAT). Mothers completed the parent version of the Pain Catastrophizing Scale. Children participated in a validated water ingestion procedure to induce abdominal discomf...

journal_title：Pain

authors： Langer SL,Romano J,Brown JD,Nielson H,Ou B,Rauch C,Zullo L,Levy RL

更新日期：2017-09-01 00:00:00

abstract：:Osteoarthritis (OA) is a major healthcare burden of increasing prevalence. It has been demonstrated that the relationship between pain and sleep produces changes in sleep patterns and pain perception. However, electrophysiological studies in animal models of pain are limited. The current study examined the effect of c...

journal_title：Pain

authors： Silva A,Andersen ML,Tufik S

更新日期：2008-12-01 00:00:00

abstract：:Primary afferent sensory neurons are incredibly long cells, often traversing distances of over 1 m in humans. Cutaneous sensory stimuli are transduced in the periphery by specialised end organs or free nerve endings, which code the stimulus into electrical action potentials that propagate towards the central nervous s...

journal_title：Pain

authors： Clark AJ,Menendez G,AlQatari M,Patel N,Arstad E,Schiavo G,Koltzenburg M

更新日期：2018-07-01 00:00:00

abstract：:The present study examined the role of catastrophizing in predicting levels of pain and disability in a sample of individuals who had sustained soft-tissue injuries to the neck, shoulders or back following work or motor vehicle accidents. Participants were 86 (27 men, 59 women) consecutive referrals to the Atlantic Pa...

journal_title：Pain

authors： Sullivan MJL,Stanish W,Waite H,Sullivan M,Tripp DA

更新日期：1998-09-01 00:00:00

abstract：:Our previous studies in the Sprague-Dawley rat showed that the intrinsic antinociceptive effects of oxycodone are naloxone reversible in a manner analogous to morphine but that in contrast to morphine, oxycodone's antinociceptive effects have a rapid onset of maximum effect (approximately 5-7 min compared to 30-45 min...

journal_title：Pain

authors： Ross FB,Smith MT

更新日期：1997-11-01 00:00:00

abstract：:Anxiety is almost inevitably present in patients facing surgery. The optimal management of postoperative pain requires the acknowledgement of perioperative anxiety and the inclusion of pharmacological and/or non-pharmacological means of alleviating the fear and worry inherent in the surgical experience. In a double-bl...

journal_title：Pain

authors： Egan KJ,Ready LB,Nessly M,Greer BE

更新日期：1992-04-01 00:00:00

abstract：:Patients with acute whiplash trauma were followed to examine if post-trauma ratings of pre-collision pain and psychological distress were associated with reduced work capability and neck pain at 12 months follow-up. The study included 740 consecutive patients (474 females, 266 males) referred from emergency department...

journal_title：Pain

authors： Carstensen TBW,Frostholm L,Oernboel E,Kongsted A,Kasch H,Jensen TS,Fink P

更新日期：2008-10-15 00:00:00

abstract：:The local anesthetic lidocaine was injected into the dentate gyrus (DG) of alert, unrestrained rats 10 min prior to investigation within the formalin test. Regional anesthesia of the DG resulted in a reduction of pain scores when administered contralateral to the site of subcutaneous formalin injection. The analgesic ...

journal_title：Pain

authors： McKenna JE,Melzack R

更新日期：1992-04-01 00:00:00

abstract：:Pain scales using faces are commonly used tools for assessing pain in children capable of communicating. However, some children require other types of pain scales because they have difficulties in understanding faces pain scales. The goal of this study was to develop and validate the "Pain Block" concrete ordinal scal...

journal_title：Pain

authors： Jung JH,Lee JH,Kim DK,Jung JY,Chang I,Kwon H,Shin J,Paek SH,Oh S,Kwak YH

更新日期：2018-04-01 00:00:00

abstract：:Intradermal injection of capsaicin induces primary hyperalgesia at the injection site and secondary hyperalgesia in the surrounding undamaged skin. The secondary hyperalgesia is thought to be due to central sensitization of the dorsal horn neurons while primary hyperalgesia is caused by sensitization of nociceptors in...

journal_title：Pain

authors： Kim HT,Park SK,Lee SE,Chung JM,Lee DH

更新日期：2001-11-01 00:00:00

abstract：:Adolescents with chronic pain are at risk for impairment in their friendships. They miss out on leisure activities, have increased school absence, may have fewer friends, are at an increased risk for victimization, and may be perceived by peers as less likeable. To help determine the source of these problems, the Soci...

journal_title：Pain

authors： Forgeron PA,McGrath P,Stevens B,Evans J,Dick B,Finley AG,Carlson T

更新日期：2011-12-01 00:00:00

abstract：:Although EMLA is known to be an effective topical anesthetic, its rate of success is unknown. Indeed, researchers have suggested that EMLA may fail with young and apprehensive children. Therefore, the objectives of this study were to assess EMLA's rate of success as well as factors which predict success. A double-blin...

journal_title：Pain

authors： Lander J,Hodgins M,Nazarali S,McTavish J,Ouellette J,Friesen E

更新日期：1996-01-01 00:00:00

abstract：:Interactions between the input from cutaneous and nociceptive muscle afferents in polysynaptic reflex pathways were investigated in man. Interaction was tested by evoking reflexes before, during, and after a period of muscle pain induced by intramuscular injection of hypertonic saline. Muscle pain was induced either i...

journal_title：Pain

authors： Andersen OK,Graven-Nielsen T,Matre D,Arendt-Nielsen L,Schomburg ED

更新日期：2000-01-01 00:00:00

abstract：:Women with chronic pelvic pain experience serious distress and lifestyle disruption. Confronted with a difficult condition to diagnose and treat effectively, doctors express a negative perception of this group of 'heartsink' patients. This study aimed to characterise medical attitudes towards the treatment of women wi...

journal_title：Pain

authors： Selfe SA,Van Vugt M,Stones WR

更新日期：1998-08-01 00:00:00

abstract：:In male rats, carrageenan (CAR)-induced inflammation or exposure to a selective protein kinase C epsilon (PKC epsilon ) agonist (psi epsilon RACK) produces prolongation of the hyperalgesia induced by a subsequent exposure to an inflammatory mediator, a phenomenon referred to as hyperalgesic priming. Since many chronic...

journal_title：Pain

authors： Joseph EK,Parada CA,Levine JD

更新日期：2003-09-01 00:00:00

abstract：:Two cases of reflex sympathetic dystrophy in the upper extremity of patients with traumatic cervical spinal cord injuries are reported. Both patients had very incomplete lesions with early neurological recovery, suggesting an underlying central cord syndrome. Although reflex sympathetic dystrophy is often seen followi...

journal_title：Pain

authors： Wainapel SF

更新日期：1984-04-01 00:00:00

abstract：:Mental stress induces endothelial dysfunction, that is a reduction of the post-occlusion brachial artery flow-mediated vasodilation (FMD). This does not occur in subjects highly susceptible to hypnosis (Highs) in either the waking or hypnotic state. The aim of the present experiment was to assess whether endothelial d...

journal_title：Pain

authors： Jambrik Z,Santarcangelo EL,Rudisch T,Varga A,Forster T,Carli G

更新日期：2005-08-01 00:00:00

abstract：:Anti-nerve growth factor (anti-NGF) therapy has shown significant promise in attenuating several types of skeletal pain. However, whether anti-NGF therapy changes the level of physical activity in individuals with or without skeletal pain is largely unknown. Here, automated day/night activity boxes monitored the effec...

journal_title：Pain

authors： Majuta LA,Mitchell SAT,Kuskowski MA,Mantyh PW

更新日期：2018-11-01 00:00:00

abstract：:Many malignant cancers, including breast cancer, have a propensity to invade bones, leading to excruciating bone pain. Opioids are the primary analgesics used to alleviate this cancer-induced bone pain (CIBP) but are associated with numerous severe side effects, including enhanced bone degradation, which significantly...

journal_title：Pain

authors： Zhang H,Lund DM,Ciccone HA,Staatz WD,Ibrahim MM,Largent-Milnes TM,Seltzman HH,Spigelman I,Vanderah TW

更新日期：2018-09-01 00:00:00

abstract：:A large body of evidence indicates that nitric oxide (NO)/cGMP signaling essentially contributes to the processing of chronic pain. In general, NO-induced cGMP formation is catalyzed by 2 isoforms of guanylyl cyclase, NO-sensitive guanylyl cyclase 1 (NO-GC1) and 2 (NO-GC2). However, the specific functions of the 2 iso...

journal_title：Pain

authors： Petersen J,Mergia E,Kennel L,Drees O,Steubing RD,Real CI,Kallenborn-Gerhardt W,Lu R,Friebe A,Koesling D,Schmidtko A

更新日期：2019-03-01 00:00:00

abstract：:Data from daily diaries were used to analyze pain coping processes in rheumatoid arthritis patients. For 30 consecutive days, 53 individuals described the pain coping strategies they used that day and rated the efficacy of their coping, joint pain, and positive and negative mood. Relations among variables were examine...

journal_title：Pain

authors： Keefe FJ,Affleck G,Lefebvre JC,Starr K,Caldwell DS,Tennen H

更新日期：1997-01-01 00:00:00

abstract：:Facial expressions of pain and emotions provide powerful social signals, which impart information about a person's state. Unfortunately, research on pain and emotion expression has been conducted largely in parallel with few bridges allowing for direct comparison of the expressive displays and their impact on observer...

journal_title：Pain

authors： Simon D,Craig KD,Gosselin F,Belin P,Rainville P

更新日期：2008-03-01 00:00:00