Chronic gynaecological pain: an exploration of medical attitudes.

abstract：:Topically applied norepinephrine, dopamine, serotonin, GABA and glycine, and systemically administered clonidine, L-DOPA (plus carbidopa) and 5-hydroxytryptophan completely suppressed the cutaneous hyper-irritability produced in the trigeminal sensory distribution by picrotoxin overlying the caudal medulla. Cholinergi...

journal_title：Pain

authors： Sakai Y,Nishijima Y,Mikuni N,Iwata N

更新日期：1981-08-01 00:00:00

abstract：:Recent meta-analyses have shown mindfulness-based interventions (MBIs) to be effective for chronic pain, but no pooled estimates of the effect of MBIs on acute pain are available. This meta-analysis was conducted to fill that gap. A literature search was conducted in 4 databases. Articles were eligible if they reporte...

journal_title：Pain

authors： Shires A,Sharpe L,Davies JN,Newton-John TRO

更新日期：2020-08-01 00:00:00

abstract：:An 82-year-old woman experienced generalized pruritus not due to skin or systemic disease. Scratching the skin with a needle induced a crisis of intense pruritus, insensitive to any drug. The pruritus had the characteristics of a central sensation. ...

journal_title：Pain

authors： Procacci P,Maresca M

更新日期：1991-06-01 00:00:00

abstract：:Phantom urinary phenomena are a relatively rare disease entity. Literature search has revealed only one case following cystectomy, seven cases following spinal cord injury and several other cases in hemodialysis patients. This report presents a case of painful phantom bladder following cystectomy for chronic kidney an...

journal_title：Pain

authors： Brena SF,Sammons EE

更新日期：1979-10-01 00:00:00

abstract：:Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the body. It has been suggested that such side bias results from corti...

journal_title：Pain

authors： Leite-Almeida H,Cerqueira JJ,Wei H,Ribeiro-Costa N,Anjos-Martins H,Sousa N,Pertovaara A,Almeida A

更新日期：2012-11-01 00:00:00

abstract：:Visceral inflammation is thought to play an important role in the sensitization of low and high threshold mechanosensory and polymodal afferents and to recruit silent nociceptors. Yet, little is known about the potential role of the mediators involved in nociceptor sensitization to mechanical stimulation as compared t...

journal_title：Pain

authors： Roza C,Reeh PW

更新日期：2001-09-01 00:00:00

abstract：:This study compared a remote-delivered pain management program, the Pain Course, when delivered in online and workbook formats. Participants (n = 178) were randomised into 2 groups: (1) an Internet Group (n = 84) who were provided with secure accounts to the program in an online format; or (2) a Workbook Group (n = 94...

journal_title：Pain

authors： Dear BF,Gandy M,Karin E,Ricciardi T,Fogliati VJ,McDonald S,Staples LG,Perry KN,Sharpe L,Nicholas MK,Titov N

更新日期：2017-07-01 00:00:00

abstract：:Test-retest reliability of a pain drawing instrument was investigated. Pain drawings of chronic pain patients (n = 51) were scored for percentage of total body surface in pain and location of pain. A test-retest reliability coefficient of r = 0.85 was calculated for a time interval that averaged 71 days. In addition, ...

journal_title：Pain

authors： Margolis RB,Chibnall JT,Tait RC

更新日期：1988-04-01 00:00:00

abstract：:Pain is processed in multiple cortical and subcortical brain areas. Subcortical structures are substantially involved in different processes that are closely linked to pain processing, e.g. motor preparation, autonomic responses, affective components and learning. However, it is unclear to which extent nociceptive inf...

journal_title：Pain

authors： Bingel U,Quante M,Knab R,Bromm B,Weiller C,Büchel C

更新日期：2002-09-01 00:00:00

abstract：:The social determinants of health (SDH) are known to differentially impact outcomes from many noncommunicable diseases; however, their potential role in low back pain (LBP) is poorly defined. This review endeavours to comprehensively inform the field of their relevance. Our research question was: "How do the broad ran...

journal_title：Pain

authors： Karran EL,Grant AR,Moseley GL

更新日期：2020-11-01 00:00:00

abstract：:Pain is a frequently observed non-motor symptom of patients with Parkinson's disease. In some patients, Parkinson's-related pain responds to dopaminergic treatment. In the present study, we aimed to elucidate whether subthalamic deep brain stimulation has a similar beneficial effect on pain in Parkinson's disease, and...

journal_title：Pain

authors： Sürücü O,Baumann-Vogel H,Uhl M,Imbach LL,Baumann CR

更新日期：2013-08-01 00:00:00

abstract：:Late-life depression and pain more often co-occur than can be explained by chance. Determinants of pain in late-life depression are unknown, even though knowledge on possible determinants of pain in depression is important for clinical practice. Therefore, the objectives of the present study were 1) to describe pain c...

journal_title：Pain

authors： Hanssen DJ,Naarding P,Collard RM,Comijs HC,Oude Voshaar RC

更新日期：2014-10-01 00:00:00

abstract：:Ninety-two knees in 46 patients were evaluated with regard to pain: in 51 of these knees, implantation of a hinged endoprosthesis had been performed. The reliability and validity of 2 pain evaluation methods were assessed: the knee-pain questionnaire method (standard version including 10 questions and modified version...

journal_title：Pain

authors： Boeckstyns MEH,Backer M

更新日期：1989-07-01 00:00:00

abstract：:Cognitive strategies have received considerable interest in pain management, alongside the traditional approaches of physical intervention and behavior modification. However, the literature on these strategies is ridden with inconsistencies of terminology that present major difficulties in the conceptualization and ev...

journal_title：Pain

authors： Fernandez E

更新日期：1986-08-01 00:00:00

abstract：:These experiments quantitatively analyzed effects of electrical midbrain stimulation on a nociceptive hind limb flexion reflex in rats anesthetized with sodium pentobarbital. We recorded the force of isometric hind limb flexion withdrawal, and related flexor electromyographic (EMG) activity, elicited by noxious heat (...

journal_title：Pain

authors： Carstens E,Campbell IG

更新日期：1988-05-01 00:00:00

abstract：:The efficacy of psychological treatments emphasising a self-management approach to chronic pain has been demonstrated by substantial empirical research. Nevertheless, high drop-out and relapse rates and low or unsuccessful engagement in self-management pain rehabilitation programs have prompted the suggestion that peo...

journal_title：Pain

authors： Strong J,Westbury K,Smith G,McKenzie I,Ryan W

更新日期：2002-05-01 00:00:00

abstract：:Postherpetic neuralgia (PHN) is a debilitating chronic pain condition, yet there is a lack of knowledge regarding underlying brain activity. Here we identify brain regions involved in spontaneous pain of PHN (n=11) and determine its modulation with Lidoderm therapy (patches of 5% lidocaine applied to the PHN affected ...

journal_title：Pain

authors： Geha PY,Baliki MN,Chialvo DR,Harden RN,Paice JA,Apkarian AV

更新日期：2007-03-01 00:00:00

abstract：:The purpose of this study was to examine racial/ethnic-related differences in a four-stage model of the processing of chronic pain. The subjects were 1557 chronic pain patients (White=1084, African American=473) evaluated at a pain management clinic at a large southeastern university medical center. Using an analysis ...

journal_title：Pain

authors： Riley JL 3rd,Wade JB,Myers CD,Sheffield D,Papas RK,Price DD

更新日期：2002-12-01 00:00:00

abstract：:A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression. Treatment was given, in randomized order, for periods of 4 weeks, separated by 1 week wash-o...

journal_title：Pain

authors： Leijon G,Boivie J

更新日期：1989-01-01 00:00:00

abstract：:In the spinal nerve ligation (SNL) model of neuropathic pain, synaptic plasticity shifts the excitation/inhibition balance toward excitation in the spinal dorsal horn. We investigated the deregulation of the synaptogenic neuroligin (NL) molecules, whose NL1 and NL2 isoforms are primarily encountered at excitatory and ...

journal_title：Pain

authors： Dolique T,Favereaux A,Roca-Lapirot O,Roques V,Léger C,Landry M,Nagy F

更新日期：2013-11-01 00:00:00

abstract：:Cognitions and beliefs appear important in predicting adjustment to chronic pain. The current study examines how cognitions and beliefs are related to psychosocial functioning. One hundred and sixty-three chronic pain out-patients were assessed. Regression analyses were performed using scores on the Pain Beliefs and P...

journal_title：Pain

authors： Stroud MW,Thorn BE,Jensen MP,Boothby JL

更新日期：2000-02-01 00:00:00

abstract：:The results of two experiments show that ratio scales of sensory and affective verbal pain descriptors are valid, reliable and objective. In the first experiment, 16 subjects rated 15 sensory and 15 affective verbal pain descriptors by numerical magnitude estimation and by cross-modality matching to handgrip force. Ra...

journal_title：Pain

authors： Gracely RH,McGrath P,Dubner R

更新日期：1978-06-01 00:00:00

abstract：:The purpose of this study was to determine if some commonly used admission variables could predict treatment outcome on a multidisciplinary pain center. Specifically, it was designed as a prospective study of an index proposed by Maruta et al. The subjects were 104 patients. The 4 outcome measures used were staff judg...

journal_title：Pain

authors： Aronoff GM,Evans WO

更新日期：1982-09-01 00:00:00

abstract：:The role of proinflammatory cytokines in neuropathic and inflammatory pain is well established. Recent studies suggest that cytokines such as tumor necrosis factor-alpha (TNF) may also be involved in the development of muscle pain. To investigate the pathophysiology of intramuscular TNF, exogenous TNF (0.1-10 microg),...

journal_title：Pain

authors： Schäfers M,Sorkin LS,Sommer C

更新日期：2003-08-01 00:00:00

abstract：:Pregnant women may take nonsteroidal antiinflammatory drugs (NSAIDs), selective cyclooxygenase (COX)-2 inhibitors, or biological agents to relieve symptoms or manage disease flares in late pregnancy. We aimed to quantify the risk of prematurity associated with late pregnancy exposure to nonselective NSAIDs, selective ...

journal_title：Pain

authors： Bérard A,Sheehy O,Girard S,Zhao JP,Bernatsky S

更新日期：2018-05-01 00:00:00

abstract：ABSTRACT:Morphine-induced alterations in sphingolipid metabolism in the spinal cord and increased formation of the bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P) have been implicated in the development of morphine-induced hyperalgesia (OIH; increased pain sensitivity) and antinociceptive tolerance. The...

journal_title：Pain

authors： Doyle TM,Janes K,Chen Z,Grace PM,Esposito E,Cuzzocrea S,Largent-Milnes TM,Neumann WL,Watkins LR,Spiegel S,Vanderah TW,Salvemini D

更新日期：2020-09-01 00:00:00

abstract：:Pain that interferes with daily life appears to be strongly age-related in cross-sectional studies, although the nature of this relationship over time has not been established. We have investigated the onset and persistence of pain and pain interference over a 3-year period to determine their association with age in o...

journal_title：Pain

authors： Thomas E,Mottram S,Peat G,Wilkie R,Croft P

更新日期：2007-05-01 00:00:00

abstract：:A visual analog scale (VAS) method of assessing headache pain was compared with a standard categorical four-grade scale (4GS) in a randomized, placebo-controlled, double-blind, clinical trial involving 792 treated migraine outpatients who received oral rizatriptan 5 mg, sumatriptan 50 mg, or placebo for a moderate or ...

journal_title：Pain

authors： Lines CR,Vandormael K,Malbecq W

更新日期：2001-08-01 00:00:00

abstract：:Bone is one of the leading sites of metastasis for frequently diagnosed malignancies, including those arising in the breast, prostate and lung. Although these cancers develop unnoticed and are painless in their primary sites, bone metastases result in debilitating pain. Deeper investigation of this pain may reveal eti...

journal_title：Pain

authors： Slosky LM,BassiriRad NM,Symons AM,Thompson M,Doyle T,Forte BL,Staatz WD,Bui L,Neumann WL,Mantyh PW,Salvemini D,Largent-Milnes TM,Vanderah TW

更新日期：2016-11-01 00:00:00

abstract：:Chronic dry eye disease (DE) is associated with an unstable tear film and symptoms of ocular discomfort. The characteristics of symptoms suggest a key role for central neural processing; however, little is known about central neuroplasticity and DE. We used a model for tear deficient DE and assessed effects on eye bli...

journal_title：Pain

authors： Rahman M,Okamoto K,Thompson R,Katagiri A,Bereiter DA

更新日期：2015-05-01 00:00:00