Orofacial pain onset predicts transition to head and neck cancer.

Abstract:

:Contrary to a clinical aphorism that early head and neck cancer is painless, we show that patients who develop head and neck cancer experience significant pain at the time of initial diagnosis. We compared orofacial pain sensitivity in groups of patients with normal oral mucosa, oral precancer, and newly diagnosed oral cancer. The University of California San Francisco Oral Cancer Pain Questionnaire was administered to these patients at their initial visit, before being prescribed analgesics for pain and before any treatment. In contrast to those with biopsy-proven normal oral mucosa and oral precancer, only oral cancer patients reported significant levels of spontaneous pain and functional restriction from pain. Moreover, oral cancer patients experienced significantly higher function-related, rather than spontaneous, pain qualities. These findings suggest an important predictor for the transition from oral precancer to cancer may be the onset of orofacial pain that is exacerbated during function. Screening patients who have new-onset orofacial pain may lead to a diagnosis of early resectable head and neck cancer and may improve quality of life and survival for head and neck cancer patients.

journal_name

Pain

journal_title

Pain

authors

Lam DK,Schmidt BL

doi

10.1016/j.pain.2011.02.009

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

1206-1209

issue

5

eissn

0304-3959

issn

1872-6623

pii

00006396-201105000-00036

journal_volume

152

pub_type

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