Immuno-electron-microscopic study of the prolactin cells in the pituitary gland of male Wistar rats during aging.

Abstract:

:Prolactin cells were identified by means of immunocytochemistry with protein-A gold as a marker on ultrathin sections of the pituitary gland of young (3-4 months), middle-aged (16-19 months), and aged (26-30 months) male Wistar rats. Point-counting volumetry revealed that the prolactin (PRL) cell-volume density in middle-aged rats was significantly increased in comparison to the volume densities in young and aged rats. Within the PRL-cell population, four types of PRL cells were distinguished on the basis of the shape and size of their secretory granules. During aging, dramatic changes occurred in the relative volumes of the four cell types. The volume percentage of cells with round granules (type I, granule diameter 150-250 nm, and type IIA, granule diameter 250-350 nm) increased from +/- 30% in young rats to +/- 90% in old rats. The volume percentage of cells with round and polymorphic granules (type IIB; granule diameter 350-400 nm and type III; granule diameter 500-600 nm) decreased from +/- 70% in young rats to +/- 7% in old rats. Age-related changes in serum PRL levels were not found. It is concluded that although during the life span of the male Wistar rat considerable changes in PRL-cell volume densities and in the ratios of PRL-cell types occur serum, PRL levels remain more or less constant.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

van Putten LJ,Kiliaan AJ

doi

10.1007/BF00215844

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

353-8

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

251

pub_type

杂志文章
  • Altered pattern of vasopressin distribution in the hypothalamus of rats subjected to immobilization stress. An immunohistochemical study.

    abstract::Generally, the CRF-like activity of vasopressin is studied in experiments involving adrenalectomy and corticosteroid replacement. In order to avoid this complex type of stress, male and female (diestrus, estrus) rats were exposed to 5 min to immobilization stress and sacrificed 5, 15, and 30 min thereafter. After a su...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00209276

    authors: Krisch B

    更新日期:1978-05-29 00:00:00

  • Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system.

    abstract::Whether an axon will regenerate after it is cut depends on the balance between the intrinisic ability of the axon to regrow and the permissiveness of the environment surrounding it. The permissiveness of the environment is determined by the glial cells at the site of injury, and in the CNS both oligodendrocytes and as...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s004410050943

    authors: Fawcett JW

    更新日期:1997-11-01 00:00:00

  • Binding of antibody to the gamma subunit of FCepsilonRI in rat basophilic leukemia cells results in morphological changes without inducing histamine release.

    abstract::The high affinity IgE receptor on mast cells and basophils is composed of 3 subunits, alpha, beta and gamma. A polyclonal antibody was raised in rabbits to a 13 amino acid synthetic peptide corresponding to the amino terminal portion of the gamma subunit. The antiserum was screened using Western blots of solubilized R...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410050575

    authors: Jamur MC,Oliver C

    更新日期:1996-04-01 00:00:00

  • Involvement of a gelsolin-related protein in spermatogenesis of the earthworm Lumbricus terrestris.

    abstract::A gelsolin-related protein was isolated from seminal vesicles of the annelid Lumbricus terrestris. Compared with the isoforms of the gelsolin-related protein previously found in the muscle of the annelid body wall, the isolated protein was assigned to the first isoform (EWAM-P1) because of its electrophoretic mobility...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-007-0561-9

    authors: Krüger E,Hinssen H,D'Haese J

    更新日期:2008-04-01 00:00:00

  • Primary culture of capillary endothelial cells from the spiral ligament and stria vascularis of bovine inner ear. Retention of several endothelial cell properties in vitro.

    abstract::Methods for isolation and culture of microvascular endothelial cells of the inner ear were devised to provide an in-vitro system for studying endothelial functions in this tissue. Capillaries from the stria vascularis and spiral ligament were treated enzymatically to free them from surrounding tissue. Contamination by...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214566

    authors: Bowman PD,Rarey K,Rogers C,Goldstein GW

    更新日期:1985-01-01 00:00:00

  • The ultrastructure of an olfactory sensillum on the maxillary palps of locusta migratoria (L.).

    abstract::The olfactory sensilla on the maxillary palp tip of Locusta migratoria (L.) resemble the surrounding contact chemoreceptors in general morphology. The perforated peg has a thicker wall than is commonly found in olfactory sensilla. The form and position of the sensilla are considered in relation of the olfactory functi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219899

    authors: Blaney WM

    更新日期:1977-11-07 00:00:00

  • Demonstration of a somatostatin-like activity in retinal cells of the rat.

    abstract::A somatostatin-like substance is demonstrated by light microscopic immunohistochemistry (PAP-method) in perikarya and cell processes of the retina of adult and infant rats. These perikarya are identified according to their size, arrangement and distribution. Each of the first two neuronal orders (receptors, bipolar ce...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00235169

    authors: Kirsch B,Leonhardt H

    更新日期:1979-01-01 00:00:00

  • Complex relationships between the pineal organ and the medial habenular nucleus-pretectal region of the mouse as revealed by S-antigen immunocytochemistry.

    abstract::S-antigen-immunoreactive pinealocytes located in the deep portion of the pineal organ of inbred and wild pigmented mice give rise to long, beaded processes penetrating into the habenular and pretectal regions. In addition, the medial habenular nuclei and the pretectal area contain S-antigen-immunoreactive perikarya, w...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00313528

    authors: Korf HW,Sato T,Oksche A

    更新日期:1990-09-01 00:00:00

  • Sequential expression of endothelial nitric oxide synthase, inducible nitric oxide synthase, and nitrotyrosine in odontoblasts and pulp cells during dentin repair after tooth preparation in rat molars.

    abstract::Nitric oxide (NO) stimulates osteoblast differentiation, but whether NO contributes to odontoblast differentiation during dentin repair is unknown. By using reverse transcription/polymerase chain reaction and immunostaining, we investigated the gene expression and/or immunolocalization of endothelial NO synthase (eNOS...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-005-0003-5

    authors: Mei YF,Yamaza T,Atsuta I,Danjo A,Yamashita Y,Kido MA,Goto M,Akamine A,Tanaka T

    更新日期:2007-04-01 00:00:00

  • Cotton rat (Sigmodon hispidus) develops metabolic disorders associated with visceral adipose inflammation and fatty pancreas without obesity.

    abstract::Obesity induces metabolic disorders such as type 2 diabetes, hypertension, and cardiovascular diseases and has become a global health concern. Recent studies imply that fat accumulation in nonadipose tissue correlates with metabolic disorders. However, there are no suitable animal models to evaluate this phenomenon. T...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-018-2908-9

    authors: Nakamura T,Ichii O,Irie T,Kouguchi H,Sotozaki K,Chihara M,Sunden Y,Nagasaki KI,Tatsumi O,Elewa YHA,Kon Y

    更新日期:2019-02-01 00:00:00

  • High affinity choline transporter immunoreactivity in rat ileum myenteric nerves.

    abstract::Recently, an antibody against the choline transporter (CHT), an essential molecule involved in ACh uptake, was used to label cholinergic nerves in the central nervous system; however, the enteric nervous system (ENS) was not examined. The present study localised CHT immunoreactivity (CHT-IR) within the rat ileum ENS a...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-006-0332-z

    authors: Harrington AM,Hutson JM,Southwell BR

    更新日期:2007-03-01 00:00:00

  • Morphological characterization of single fan-shaped body neurons in Drosophila melanogaster.

    abstract::The fan-shaped body is the largest substructure of the central complex in Drosophila melanogaster. Two groups of large-field neurons that innervate the fan-shaped body, viz., F1 and F5 neurons, have recently been found to be involved in visual pattern memory for "contour orientation" and "elevation" in a rut-dependent...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-009-0781-2

    authors: Li W,Pan Y,Wang Z,Gong H,Gong Z,Liu L

    更新日期:2009-06-01 00:00:00

  • Gomori-positive elementary granules in inner and outer layer of the infundibulum.

    abstract::With the gallocyanine technique (Wittkowski, Bock and Franken, 1970) Gomori-positive substances of the infundibulum can be stained for light- and electron-microscopic examination. In various mammalian species, the size of Gomori-positive elementary granules in the outer layer is markedly different from that in the inn...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00218495

    authors: Brinkmann H,Wittkowski W,Bock R

    更新日期:1975-11-19 00:00:00

  • Effect of synthetic peptides derived from SCO-spondin conserved domains on chick cortical and spinal-cord neurons in cell cultures.

    abstract::SCO-spondin is a newly identified protein, strongly expressed in the subcommissural organ (SCO), an ependymal differentiation of the brain. When secreted into the cerebrospinal fluid at the entrance to the Sylvian aqueduct, it condenses and forms Reissner's fiber. Several conserved domains have previously been charact...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051132

    authors: Monnerie H,Dastugue B,Meiniel A

    更新日期:1998-09-01 00:00:00

  • Absolute volume of differentiating cells in the epithelium of the human hard palate.

    abstract::In previous studies the differentiation of the epithelium in the human hard palate has been described stereologically using parameters expressed per unit tissue volume. Since single epithelial cells represent the true biological units of this tissue, it became necessary to estimate the absolute size of such cells in o...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00216577

    authors: Müller-Glauser W

    更新日期:1981-01-01 00:00:00

  • Embryonic and postnatal development of masticatory and tongue muscles.

    abstract::This review summarizes findings concerning the unique developmental characteristics of mouse head muscles (mainly the masticatory and tongue muscles) and compares their characteristics with those of other muscles. The developmental origin of the masticatory muscles is the somitomeres, whereas the tongue and other musc...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-005-0019-x

    authors: Yamane A

    更新日期:2005-11-01 00:00:00

  • Annexins in rat enterocyte and hepatocyte: an immunogold electron-microscope study.

    abstract::In the present study, immunogold labeling of ultrathin sections of rat small intestine and liver has been used to obtain insights into the ultrastructural localization and possible functions of annexins. In enterocytes, annexins II, IV, and VI are found at the periphery of the core of each microvillus and of the rootl...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00414181

    authors: Weinman JS,Feinberg JM,Rainteau DP,Gaspera BD,Weinman SJ

    更新日期:1994-11-01 00:00:00

  • The effect of colchicine on protein secretion by differentiating odontoblasts and ameloblasts in the hamster tooth in vitro as shown by radioautography with 3H-proline.

    abstract::We have examined radioautographically the protein synthetic and secretory activity of differentiating odontoblasts and ameloblasts, exposed for 9 h in vitro to various concentrations of colchicine in the presence of 3H-proline. Colchicine impairs the cytodifferentiation of the dental epithelium into ameloblasts and of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00216651

    authors: Bronckers AL,Lyaruu DM,Bervoets TJ,Wöltgens JH

    更新日期:1988-06-01 00:00:00

  • Effects of colchicine on the ultrastructure of mouse taste buds.

    abstract::Effect of colchicine on the ultrastructure of taste bud cells was studied in the mouse. In untreated mice microtubules were abundant throughout the entire cytoplasm of type-III cells, but only in the apical cytoplasm of type-I cells. After 2 h of colchicine treatment, no microtubules were observed in any taste bud cel...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214555

    authors: Takeda M,Suzuki Y,Shishido Y

    更新日期:1985-01-01 00:00:00

  • Histochemical and radioautographic study of glycoprotein secretion in the epithelium lining the uterine tubes of mice.

    abstract::Two-month-old female Swiss mice that had come into estrus were injected intravenously with L-3H-fucose and killed at 5, 15, 40 min, and 4 h after injection. Pieces of the isthmus and of the ampulla of the uterine tubes were processed for light- and electron-microscopic radioautography. Incorporation of 3H-fucose was m...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00220036

    authors: Teixeira ML,Haddad A

    更新日期:1988-10-01 00:00:00

  • Histone methylation during neural development.

    abstract::Post-translational modification of histone proteins, such as the methylation of lysine and arginine residues, influences the higher order of chromatin and leads to gene activation or silencing. Histone methyltransferases or demethylases actively add or remove various methylation marks in a cell-type-specific and conte...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-014-1842-8

    authors: Roidl D,Hacker C

    更新日期:2014-06-01 00:00:00

  • Distribution of PACAP (pituitary adenylate cyclase-activating polypeptide)-like and helospectin-like peptides in the teleost gut.

    abstract::Pituitary adenylate cyclase-activating polypeptide (PACAP) and helospectin are two vasoactive intestinal polypeptide (VIP)-related neuropeptides that have recently been demonstrated in the mammalian gut; the aim of this study was to reveal their occurrence and localisation in the gastrointestinal tract, swimbladder, u...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00300227

    authors: Olsson C,Holmgren S

    更新日期:1994-09-01 00:00:00

  • An electron microscopic, enzyme cytochemical study on the localization of lactate dehydrogenase (LDH) in osteoclasts and peritoneal macrophages of the rat and its implication for the process of bone resorption and the origin of osteoclasts.

    abstract::LDH is localized along various intracytoplasmatic membranes of osteoclasts. Macrophages show membrane-bound LDH only after phagocytosis of calcium hydroxylapatite, the main mineral constituent of bone. The localization of LDH in these macrophages is almost the same as in osteoclasts. The significance of this finding, ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219927

    authors: Touw JJ,Hemrika-Wagner AM,Vermeiden JP

    更新日期:1980-01-01 00:00:00

  • Movement of villi induces endocytosis of NK1 receptors in myenteric neurons from guinea-pig ileum.

    abstract::Agitation of villi evokes reflexes that affect the motility of the guinea-pig small intestine. NK1 receptor endocytosis was used to investigate the possible involvement of tachykinins acting on neuronal NK1 receptors in these reflexes. Segments of guinea-pig ileum were incubated at 37 degrees C in Krebs physiological ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051032

    authors: Southwell BR,Woodman HL,Royal SJ,Furness JB

    更新日期:1998-04-01 00:00:00

  • The effect of l-thyroxine on the metamorphosis of Ascidia malaca.

    abstract::Larvae of Ascidia malaca, both before and after hatching, were treated with L-thyroxine solutions. The effect of the thyroid hormone was to induce the onset of metamorphosis and then to cause the rate at which body reorganization occurred to increase. In treated larvae the resorption of the tail occurred only few hour...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00249213

    authors: Patricolo E,Ortolani G,Cascio A

    更新日期:1981-01-01 00:00:00

  • Apoptotic and antiapoptotic mechanisms in stroke.

    abstract::Apoptosis is a form of programmed cell death that occurs in neurons during development of the nervous system and may also be a prominent form of neuronal death in chronic neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Recent findings also implicate apoptosis in neuronal degeneration after is...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s004419900154

    authors: Mattson MP,Culmsee C,Yu ZF

    更新日期:2000-07-01 00:00:00

  • Musculoskeletal tissue engineering by endogenous stem/progenitor cells.

    abstract::From its inception, tissue engineering has had three tenets: cells, biomaterial scaffolds and signaling molecules. Among the triad, cells are the center piece, because cells are the building blocks of tissues. For decades, cell therapies have focused on the procurement, manipulation and delivery of healthy cells for t...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-012-1339-2

    authors: Nie H,Lee CH,Tan J,Lu C,Mendelson A,Chen M,Embree MC,Kong K,Shah B,Wang S,Cho S,Mao JJ

    更新日期:2012-03-01 00:00:00

  • Localization of VIP-immunoreactive nerves in airways and pulmonary vessels of dogs, cat, and human subjects.

    abstract::VIP-containing neurons were localized in lungs from dogs, cat, and human subjects by means of the indirect immunofluorescence technique. Nerve fibers and terminals were observed in the smooth muscle layer and glands of airways, and within the walls of pulmonary and bronchial vessels, especially at the medial-adventiti...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00210505

    authors: Dey RD,Shannon WA Jr,Said SI

    更新日期:1981-01-01 00:00:00

  • DNA methylation levels in porcine fetal fibroblasts induced by an inhibitor of methylation, 5-azacytidine.

    abstract::Removal of the somatic DNA methylation pattern from donor cells and remodeling of embryonic status have been suggested as integral processes for successful nuclear transfer (NT) reprogramming. This study has investigated the effects of 5-azacytidine (5-azaC), a DNA methylation inhibitor, on global methylation changes ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-006-0201-9

    authors: Mohana Kumar B,Jin HF,Kim JG,Song HJ,Hong Y,Balasubramanian S,Choe SY,Rho GJ

    更新日期:2006-09-01 00:00:00

  • Extracellular glycosaminoglycans (GAG) released by chick embryonic fibroblasts. A possible involvement of surface receptors.

    abstract::Administration of Concanavalin A (Con A) to cultured skin fibroblasts derived from chick embryos at two developmental stages produce variations in the relative concentration of individual glycosaminoglycan (GAG) secreted by the cells. This effect is different: at 7 days (increase of hyaluronic acid and dermatan sulpha...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00217295

    authors: Evangelisti R,Bodo M,Caruso A,Becchetti E,Carinci P

    更新日期:1984-01-01 00:00:00