Thermoresponsive motor behavior is mediated by ring neuron circuits in the central complex of Drosophila.

abstract：:Incident myocardial infarction (MI) is a leading cause of adult mortality in the United States. However, because MI has a relatively low incidence in the young population, little information exists on the disease in younger adults. Because the retina has the unique quality that its vasculature is readily and noninvasi...

journal_title：Scientific reports

authors： Kromer R,Tigges E,Rashed N,Pein I,Klemm M,Blankenberg S

更新日期：2018-04-04 00:00:00

abstract：:Biosynthesis of sakuranetin, a flavonoid anti-fungal phytoalexin that occurs in rice, is highly dependent on jasmonic acid (JA) signalling and induced by a variety of environmental stimuli. We previously identified OsNOMT, which encodes naringenin 7-O-methyltransferase (NOMT); NOMT is a key enzyme for sakuranetin prod...

journal_title：Scientific reports

authors： Ogawa S,Miyamoto K,Nemoto K,Sawasaki T,Yamane H,Nojiri H,Okada K

更新日期：2017-01-09 00:00:00

abstract：:Dravet syndrome is the prototype of SCN1A-mutation associated epilepsies. It is characterised by prolonged seizures, typically provoked by fever. We describe the evaluation of an SCN1A mutation in a child with early-onset temperature-sensitive seizures. The patient carries a heterozygous missense variant (c3818C > T; ...

journal_title：Scientific reports

authors： Peters C,Rosch RE,Hughes E,Ruben PC

更新日期：2016-09-01 00:00:00

abstract：:Transverse-tubules (T-tubules) play pivotal roles in Ca2+-induced, Ca2+ release and excitation-contraction coupling in cardiomyocytes. The purpose of this study was to uncover mechanisms where sarco/endoplasmic reticulum Ca2+ ATPase (SERCA2a) improved cardiac function through T-tubule regulation during myocardial isch...

journal_title：Scientific reports

authors： Wang S,Zhou Y,Luo Y,Kan R,Chen J,Xuan H,Wang C,Chen J,Xu T,Li D

更新日期：2021-01-21 00:00:00

abstract：:Liver failure, whether arising directly from acute liver failure or from decompensated chronic liver disease is an increasing problem worldwide and results in many deaths. In the UK only 10% of individuals requiring a liver transplant receive one. Thus the need for alternative treatments is paramount. A BioArtificial ...

journal_title：Scientific reports

authors： Selden C,Bundy J,Erro E,Puschmann E,Miller M,Kahn D,Hodgson H,Fuller B,Gonzalez-Molina J,Le Lay A,Gibbons S,Chalmers S,Modi S,Thomas A,Kilbride P,Isaacs A,Ginsburg R,Ilsley H,Thomson D,Chinnery G,Mankahla N,Loo

更新日期：2017-11-06 00:00:00

abstract：:We propose an internal (on-chip) Wheatstone bridge configuration to evaluate the efficiency of near-field transducers (NFT) as used in heat-assisted magnetic recording (HAMR). The electric field enhancement between the transducer and the image plane is monitored by measuring the resistance of metal electrodes composin...

journal_title：Scientific reports

authors： Gosciniak J,Mooney M,Gubbins M,Corbett B

更新日期：2016-04-14 00:00:00

abstract：:The aims of this study were to explore whether DNA methylation at INSR and IGF2 mediated the association of prenatal exposure to the Chinese great famine with adulthood waist circumference (WC) and BMI. A total of 235 subjects were selected into the present study from severely affected province and a neighbor province...

journal_title：Scientific reports

authors： Wang Z,Song J,Li C,Li Y,Shen L,Dong B,Zou Z,Ma J

更新日期：2020-07-22 00:00:00

abstract：:We demonstrate the surface-plasmon-induced enhancement of Förster resonance energy transfer (FRET)using a model multilayer core-shell nanostructure consisting of an Au core and surrounding FRET pairs, i.e., CdSe quantum dot donors and S101 dye acceptors. The multilayer configuration was demonstrated to exhibit synergi...

journal_title：Scientific reports

authors： Kochuveedu ST,Son T,Lee Y,Lee M,Kim D,Kim DH

更新日期：2014-04-22 00:00:00

abstract：:The relationship between the cuprate pseudogap (Δ(p)) and superconducting gap (Δ(s)) remains an unsolved mystery. Here, we present a temperature- and doping-dependent tunneling study of submicron Bi(2)Sr(2)CaCu(2)O(8+δ) intrinsic Josephson junctions, which provides a clear evidence that Δ(s) closes at a temperature T(...

journal_title：Scientific reports

authors： Ren JK,Zhu XB,Yu HF,Tian Y,Yang HF,Gu CZ,Wang NL,Ren YF,Zhao SP

更新日期：2012-01-01 00:00:00

abstract：:B cells have been reported to promote graft rejection through alloantibody production. However, there is growing evidence that B cells can contribute to the maintenance of tolerance. Here, we used a mouse model of MHC-class I mismatched skin transplantation to investigate the contribution of B cells to graft survival....

journal_title：Scientific reports

authors： Alhabbab R,Blair P,Elgueta R,Stolarczyk E,Marks E,Becker PD,Ratnasothy K,Smyth L,Safinia N,Sharif-Paghaleh E,O'Connell S,Noelle RJ,Lord GM,Howard JK,Spencer J,Lechler RI,Lombardi G

更新日期：2015-06-25 00:00:00

abstract：:The regeneration of WPAC through pyrolysis and its adsorption capacity of phosphorus were studied. The optimum conditions for WPAC regeneration were 650 °C and 2 h which resulted in a recovery of BET surface and total pore volume with a value of 1161.4 m2/g and 1.2176 m3/g. WPAC had a maximum PO43--P adsorption capaci...

journal_title：Scientific reports

authors： Li Y,Jin H,Liu W,Su H,Lu Y,Li J

更新日期：2018-01-15 00:00:00

abstract：:Grading of essential hypertension according to blood pressure (BP) level may not adequately reflect clinical heterogeneity of hypertensive patients. This study was carried out to explore clinical phenotypes in essential hypertensive patients using cluster analysis. This study recruited 513 hypertensive patients and ev...

journal_title：Scientific reports

authors： Guo Q,Lu X,Gao Y,Zhang J,Yan B,Su D,Song A,Zhao X,Wang G

更新日期：2017-03-07 00:00:00

abstract：:Inorganic semiconductors such as III-V materials are very important in our everyday life as they are used for manufacturing optoelectronic and microelectronic components with important applications span from energy harvesting to telecommunications. In some applications, these components are required to operate in hars...

journal_title：Scientific reports

authors： Ng WH,Lu Y,Liu H,Carmalt CJ,Parkin IP,Kenyon AJ

更新日期：2018-02-23 00:00:00

abstract：:Human motor skill learning is driven by the necessity to adapt to new situations. While supportive contacts are essential for many tasks, little is known about their impact on motor learning. To study the effect of contacts an innovative full-body experimental paradigm was established. The task of the subjects was to ...

journal_title：Scientific reports

authors： Rueckert E,Čamernik J,Peters J,Babič J

更新日期：2016-06-22 00:00:00

abstract：:Drug-induced cholestasis is a leading cause of drug withdrawal. However, the use of primary human hepatocytes (PHHs), the gold standard for predicting cholestasis in vitro, is limited by their high cost and batch-to-batch variability. Mature hepatocyte characteristics have been observed in human induced hepatocytes (h...

journal_title：Scientific reports

authors： Ni X,Gao Y,Wu Z,Ma L,Chen C,Wang L,Lin Y,Hui L,Pan G

更新日期：2016-12-09 00:00:00

abstract：:The nervous system controls most rhythmic behaviors, with a remarkable exception. In Caenorhabditis elegans periodic defecation rhythm does not appear to involve the nervous system. Such oscillations are studied in detail with genetic and molecular biology tools. The small size of C. elegans cells impairs the use of s...

journal_title：Scientific reports

authors： Kuznetsov VP,Slivko-Koltchik GA,Voronov DA,Panchin YV

更新日期：2017-12-19 00:00:00

abstract：:Mucosal associated invariant T (MAIT) cells are important for immune defense against infectious pathogens and regulate the pathogenesis of various inflammatory diseases. However, their roles in the development of colorectal cancer (CRC) are still unclear. This study examined the phenotype, distribution, clinical relev...

journal_title：Scientific reports

authors： Ling L,Lin Y,Zheng W,Hong S,Tang X,Zhao P,Li M,Ni J,Li C,Wang L,Jiang Y

更新日期：2016-02-03 00:00:00

abstract：:Postmortem diagnosis of cantharidin-induced myocardial injury and postmortem interval estimation (PMI) are the challenges in forensic science. Cardiac biomarkers play an important role in the prediction and diagnosis of myocardial injury and can be used to determine the PMI. Based on the evidence, we aimed to explore ...

journal_title：Scientific reports

authors： Zhang Y,Yu Y,Zhang J,Guan C,Liu L,Ren L

更新日期：2020-07-21 00:00:00

abstract：:The Lhasa terrane is a key region for understanding the paleoelevation of the southern Tibetan Plateau after India-Asia collision. The Gerze Basin, located in the northern part of the Lhasa terrane, is a shortening-related basin. We discovered Lagena laevis (Bandy) fossils in upper Eocene strata of the Gerze Basin. Th...

journal_title：Scientific reports

authors： Wei Y,Zhang K,Garzione CN,Xu Y,Song B,Ji J

更新日期：2016-06-08 00:00:00

abstract：:The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. This has important implic...

journal_title：Scientific reports

authors： Zhang H,Lim HS,Knapp B,Deane CM,Aleksic M,Dushek O,van der Merwe PA

更新日期：2016-10-13 00:00:00

abstract：:Loss of stromal Caveolin-1 (CAV1) expression is associated with poor prognosis in various cancers. We evaluated the prognostic value of CAV1 expression of both cancer cells and stromal cells in colorectal liver metastases (CRLM) in patients undergoing hepatectomy. In this retrospective study, 109 patients were enrolle...

journal_title：Scientific reports

authors： Neofytou K,Pikoulis E,Petrou A,Agrogiannis G,Petrides C,Papakonstandinou I,Papalambros A,Aggelou A,Kavatzas N,Liakakos T,Felekouras E

更新日期：2017-05-17 00:00:00

abstract：:Keratoconus (KC) is an ectatic corneal disease characterized by progressive thinning and irregular astigmatism, and a leading indication for corneal transplantation. KC-associated changes have been demonstrated for the entire cornea, but the pathological thinning and mechanical weakening is usually localized. We perfo...

journal_title：Scientific reports

authors： Yam GH,Fuest M,Zhou L,Liu YC,Deng L,Chan AS,Ong HS,Khor WB,Ang M,Mehta JS

更新日期：2019-02-27 00:00:00

abstract：:Organochlorine (OC) pesticides and the more persistent polychlorinated biphenyls (PCBs) have well-established dose-dependent toxicities to birds, fish and mammals in experimental studies, but the actual impact of OC pollutants on European marine top predators remains unknown. Here we show that several cetacean species...

journal_title：Scientific reports

authors： Jepson PD,Deaville R,Barber JL,Aguilar À,Borrell A,Murphy S,Barry J,Brownlow A,Barnett J,Berrow S,Cunningham AA,Davison NJ,Ten Doeschate M,Esteban R,Ferreira M,Foote AD,Genov T,Giménez J,Loveridge J,Llavona Á,Mart

更新日期：2016-01-14 00:00:00

abstract：:The ultrathin SmCo5 nanoflakes with average thickness smaller than 50 nm are prepared by a novel method of solid particle (NaCl) and surfactant co-assisted ball milling. The as-prepared nanoflakes exhibit a narrower thickness distribution of 10-50 nm and high coercivity of 23 kOe. The possible formation mechanism of n...

journal_title：Scientific reports

authors： Zuo WL,Zhao X,Zhao TY,Hu FX,Sun JR,Shen BG

更新日期：2016-05-13 00:00:00

abstract：:Functional DNA sub-sequences and genome elements are spatially clustered through the genome just as keywords in literary texts. Therefore, some of the methods for ranking words in texts can also be used to compare different DNA sub-sequences. In analogy with the literary texts, here we claim that the distribution of d...

journal_title：Scientific reports

authors： Moghaddasi H,Khalifeh K,Darooneh AH

更新日期：2017-01-27 00:00:00

abstract：:A unique combination of useful properties in boron-carbide, such as extreme hardness, excellent fracture toughness, a low density, a high melting point, thermoelectricity, semi-conducting behavior, catalytic activity and a remarkably good chemical stability, makes it an ideal material for a wide range of technological...

journal_title：Scientific reports

authors： Mondal S,Bykova E,Dey S,Ali SI,Dubrovinskaia N,Dubrovinsky L,Parakhonskiy G,van Smaalen S

更新日期：2016-01-18 00:00:00

abstract：:Ecological adaptations to seasonal changes are often observed in the phenotypic traits of plants and animals, and these adaptations are usually expressed through the production of different biochemical end products. In this study, ecological adaptations are observed in a biochemical pathway without alteration of the e...

journal_title：Scientific reports

authors： Hirata H,Ohnishi T,Tomida K,Ishida H,Kanda M,Sakai M,Yoshimura J,Suzuki H,Ishikawa T,Dohra H,Watanabe N

更新日期：2016-02-01 00:00:00

abstract：:We here investigated whether the unique capacity of mesenchymal stem cells (MSCs) to re-establish tissue homeostasis depends on their potential to sense danger associated molecular pattern (DAMP) and to mount an adaptive response in the interest of tissue repair. Unexpectedly, after injection of MSCs which had been pr...

journal_title：Scientific reports

authors： Basu A,Munir S,Mulaw MA,Singh K,Crisan D,Sindrilaru A,Treiber N,Wlaschek M,Huber-Lang M,Gebhard F,Scharffetter-Kochanek K

更新日期：2018-04-18 00:00:00

abstract：:O antigen (O-Ag) in many bacteria is synthesized via the Wzx/Wzy-dependent pathway in which Wzy polymerizes lipid-linked O-Ag subunits to modal lengths regulated by Wzz. Characterization of 83 site-directed mutants of Wzy from Pseudomonas aeruginosa PAO1 (WzyPa) in topologically-mapped periplasmic (PL) and cytoplasmic...

journal_title：Scientific reports

authors： Islam ST,Huszczynski SM,Nugent T,Gold AC,Lam JS

更新日期：2013-12-06 00:00:00

abstract：:Among abundant reconstructions of Holocene climate in Europe, only a handful has addressed winter conditions, and most of these are restricted in length and/or resolution. Here we present a record of late autumn through early winter air temperature and moisture source changes in East-Central Europe for the Holocene, b...

journal_title：Scientific reports

authors： Perșoiu A,Onac BP,Wynn JG,Blaauw M,Ionita M,Hansson M

更新日期：2017-04-26 00:00:00