Abstract:
:The Lhasa terrane is a key region for understanding the paleoelevation of the southern Tibetan Plateau after India-Asia collision. The Gerze Basin, located in the northern part of the Lhasa terrane, is a shortening-related basin. We discovered Lagena laevis (Bandy) fossils in upper Eocene strata of the Gerze Basin. This type of foraminifera is associated with lagoon and estuarine environments, indicating that the northern part of the Lhasa terrane was near sea level during the late Eocene. We speculate that these foraminifera were transported inland by storm surges to low elevation freshwater lakes during times of marine transgressions. This inference is consistent with the relatively positive δ(18)O values in carbonate from the same deposits that indicate low palaeoelevations close to sea level. Considering the palaeoelevation results from the nearby Oligocene basins at a similar latitude and the volcanic history of the Lhasa terrane, we infer that large-magnitude surface uplift of the northern Lhasa terrane occurred between late Eocene and late Oligocene time.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Wei Y,Zhang K,Garzione CN,Xu Y,Song B,Ji Jdoi
10.1038/srep27508subject
Has Abstractpub_date
2016-06-08 00:00:00pages
27508issn
2045-2322pii
srep27508journal_volume
6pub_type
杂志文章abstract::Little is known about the effects of posterior tethers on the development of proximal junctional kyphosis (PJK). We evaluated the ability of posterior tethers to the proximal motion segment stiffness in long instrumented spinal instrumentation and fusion using a whole body human FE model. A series of finite element (F...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59179-w
更新日期:2020-02-26 00:00:00
abstract::The high neutron detection efficiency, good gamma-ray discrimination and non-toxicity of 3He made of proportional counters filled with this gas the obvious choice for neutron detection, particularly in radiation portal monitors (RPM), used to control the illicit transport of nuclear material, of which neutron detector...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41699
更新日期:2017-02-09 00:00:00
abstract::The role of miRNAs in mediating insecticide resistance remains largely unknown, even for the model species Drosophila melanogaster. Building on prior research, this study used microinjection of synthetic miR-310s mimics into DDT-resistant 91-R flies and observed both a significant transcriptional repression of computa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71250-0
更新日期:2020-09-01 00:00:00
abstract::Measurement techniques that allow the global analysis of cellular responses while retaining single-cell sensitivity are increasingly needed in order to understand complex and dynamic biological processes. In this context, compromises between sensitivity, degree of multiplexing, throughput, and invasiveness are often u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53428-3
更新日期:2019-11-19 00:00:00
abstract::Increasingly, in vivo imaging holds a strategic position in bio-pharmaceutical innovation. We will present the implementation of an integrated multimodal imaging setup enabling the assessment of multiple, complementary parameters. The system allows the fusion of information provided by: Near infrared fluorescent bioma...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59561-8
更新日期:2020-02-14 00:00:00
abstract::Food webs in high-latitude oceans are dominated by relatively few species. Future ocean and sea-ice changes affecting the distribution of such species will impact the structure and functioning of whole ecosystems. Antarctic krill (Euphausia superba) is a key species in Southern Ocean food webs, but there is little und...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07205-9
更新日期:2017-07-31 00:00:00
abstract::Autophagy is a lysosomal degradation pathway that plays an essential role in neuronal homeostasis and is perturbed in many neurological diseases. Transcriptional downregulation of fat was previously observed in a Drosophila model of the polyglutamine disease Dentatorubral-pallidoluysian atrophy (DRPLA) and this was sh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52684-7
更新日期:2019-11-06 00:00:00
abstract::Mesenchymal stem cells (MSCs) are multi-potent cells that are self-renewable and possess the potential to differentiate into multiple lineages. Several studies demonstrated that MSCs could regulate a Th17/Treg balance and could be a potential therapeutic target for Rheumatoid Arthritis (RA). A20 is highly expressed in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18693-0
更新日期:2018-01-11 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-67129-9
更新日期:2020-06-17 00:00:00
abstract::Worldwide variation in human stature and limb proportions is widely accepted to reflect thermal adaptation, but the contribution of population history to this variation is unknown. Furthermore, stature and relative lower limb length (LLL) show substantial plastic responses to environmental stressors, e.g., nutrition, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79501-w
更新日期:2021-01-11 00:00:00
abstract::The Centiloid (CL) is a method for standardizing amyloid beta (Aβ) quantification through different ligands and methods. To find the most appropriate reference region to reduce the variance in the Aβ CL unit between 18F-florbetaben (FBB) and 18F-flutemetamol (FMM), we conducted head-to-head comparisons from 56 partici...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70978-z
更新日期:2020-09-11 00:00:00
abstract::Aggressive interactions between groups are frequent in human societies and can bear significant fitness costs and benefits (e.g. death or access to resources). During between-group competitive interactions, more cohesive groups (i.e. groups formed by individuals who cooperate in group defence) should out-perform less ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43277
更新日期:2017-02-24 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-72921-8
更新日期:2020-09-24 00:00:00
abstract::Because of the lack of cell wall, Micoplasma species require a fine control of membrane fluidity and integrity. mg517 is an essential gene of Mycoplasma genitalium responsible for the biosynthesis of membrane glycoglycerolipids. It encodes for a unique glycosyltransferase (MG517) with processive activity, transferring...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42970-9
更新日期:2019-05-08 00:00:00
abstract::Nonalcoholic fibrosing steatohepatitis is a uniform process throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been suggested to modulate cellular processes in liver diseases. However, the functional role of miRNAs in nonalcoholic fibrosing steatohepatitis is largely unclear. In this study, w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16163
更新日期:2015-11-05 00:00:00
abstract::Obesity involves alterations in transcriptional programs that can change in response to genetic and environmental signals through chromatin modifications. Since chromatin modifications involve different biochemical, neurological and molecular signaling pathways related to energy homeostasis, we hypothesize that geneti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22231-x
更新日期:2018-03-02 00:00:00
abstract::The evolution of cooperation is a fundamental problem in biology, especially for non-relatives, where indirect fitness benefits cannot counter within-group inequalities. Multilevel selection models show how cooperation can evolve if it generates a group-level advantage, even when cooperators are disadvantaged within t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29828
更新日期:2016-07-28 00:00:00
abstract::Low intensity transcranial focused ultrasound (LIFU) is a promising method of non-invasive neuromodulation that uses mechanical energy to affect neuronal excitability. LIFU confers high spatial resolution and adjustable focal lengths for precise neuromodulation of discrete regions in the human brain. Before the full p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62265-8
更新日期:2020-03-27 00:00:00
abstract::Fast volumetric microscopy is required to monitor large-scale neural ensembles with high spatio-temporal resolution. Widefield fluorescence microscopy can image large 2D fields of view at high resolution and speed while remaining simple and costeffective. A focal sweep add-on can further extend the capacity of widefie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26240-8
更新日期:2018-05-21 00:00:00
abstract::Fungal endophytes isolated from mountain-cultivated ginseng (MCG, Panax ginseng Meyer) were explored for their diversity and biocontrol activity against ginseng pathogens (Alternaria panax, Botrytis cinerea, Cylindrocarpon destructans, Pythium sp. and Rhizoctonia solani). A total of 1,300 isolates were isolated from t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16181-z
更新日期:2017-11-24 00:00:00
abstract::Arachidonic acid (AA) is metabolized to diverse bioactive lipid mediators. Whereas the 5-lipoxygenase-activating protein (FLAP) facilitates AA conversion by 5-lipoxygenase (5-LOX) to pro-inflammatory leukotrienes (LTs), the soluble epoxide hydrolase (sEH) degrades anti-inflammatory epoxyeicosatrienoic acids (EETs). Ac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09795-w
更新日期:2017-08-24 00:00:00
abstract::Emergence of new molecules acting directly on the hepatitic C virus (HCV) has improved treatment outcomes. However, there is a risk of selecting viral escape mutants, so a new combination is needed using different inhibitors that target different steps of the HCV infectious cycle. Novel single tablet formulations were...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49973-6
更新日期:2019-09-19 00:00:00
abstract::Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36700-w
更新日期:2019-01-23 00:00:00
abstract::Glaulactams A-C (1-3), which possess a novel skeleton, as well as the known compound daphmanidin B (4), were isolated from the leaves of Daphniphyllum glaucescens and separated using ion-exchange chromatography aided by NMR fingerprinting. Their structures, including their absolute configurations, were elucidated by s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33748-6
更新日期:2018-10-18 00:00:00
abstract::The human pathogen Legionella pneumophila delivers a large array of the effector proteins into host cells using the Dot/Icm type IVB secretion system. Among the proteins composing the Dot/Icm system, an inner membrane protein DotI is known to be crucial for the secretion function but its structure and role in type IV ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10912
更新日期:2015-06-03 00:00:00
abstract::Beneficial effects of CO2 on photosynthetic organisms will be a key driver of ecosystem change under ocean acidification. Predicting the responses of macroalgal species to ocean acidification is complex, but we demonstrate that the response of assemblages to elevated CO2 are correlated with inorganic carbon physiology...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46297
更新日期:2017-04-18 00:00:00
abstract::To evaluate crop rotation effects on maize seedling performance and its associated microbiome, maize plants were grown in the greenhouse in soils preceded by either maize, pea, soybean or sunflower. Soils originated from a replicated field experiment evaluating different four-year rotation combinations. In the greenho...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15955-9
更新日期:2017-11-16 00:00:00
abstract::This study examines the analytical and numerical solution of electromagnetic surface waves supported by a resistive metasurface-covered grounded metamaterial structure. To simulate the metamaterial, the Kramers-Kronig relation based on the causality principle is used, while the modeling of the resistive metasurface ha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72396-7
更新日期:2020-09-23 00:00:00
abstract::Many real networks feature the property of nestedness, i.e. the neighbours of nodes with a few connections are hierarchically nested within the neighbours of nodes with more connections. Despite the abstract simplicity of this notion, various mathematical definitions of nestedness have been proposed, sometimes giving ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76300-1
更新日期:2020-11-16 00:00:00
abstract::In this work, cerium-diethyldithiocarbamate (Ce-DEDTC) complex was synthesized as a novel anti-corrosion pigment. The structure of the synthesized pigment was characterized by employing Fourier transfer infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, inductively coupled plasma optical emission sp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61946-8
更新日期:2020-03-19 00:00:00