Abstract：
:Head and neck cancer (HNC), the seventh most common form of cancer worldwide, is a group of epithelial malignancies affecting sites in the upper aerodigestive tract. The 5-year overall survival for patients with HNC has stayed around 40-50% for decades, with mortality being attributable mainly to late diagnosis and recurrence. Recently, non-coding RNAs, including tRNA halves, YRNA fragments, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), have been identified in the blood and saliva of patients diagnosed with HNC. These observations have recently fueled the study of their potential use in early detection, diagnosis, and risk assessment. The present review focuses on recent insights and the potential impact that circulating non-coding RNA evaluation may have on clinical decision-making in the management of HNC.
journal_name
Cellsjournal_title
Cellsauthors
Diez-Fraile A,Ceulaer J,Derpoorter C,Spaas C,Backer T,Lamoral P,Abeloos J,Lammens Tdoi
10.3390/cells10010048subject
Has Abstractpub_date
2020-12-31 00:00:00issue
1issn
2073-4409pii
cells10010048journal_volume
10pub_type
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