The transcriptome of anterior regeneration in earthworm Eudrilus eugeniae.

abstract：:Apoptotic response in hepatocellular carcinoma (HCC) cells is impaired because of interconnectivity of proteins into complexes and signaling networks that are highly divergent in time and space. TNF-related apoptosis-inducing ligand (TRAIL) has emerged as an attractive anticancer agent reported to selectively induce a...

journal_title：Molecular biology reports

authors： Fayyaz S,Yaylim I,Turan S,Kanwal S,Farooqi AA

更新日期：2014-10-01 00:00:00

abstract：:Three members of Brassica napus TRANSPARENT TESTA 2 (BnTT2) gene family encoding potential R2R3-MYB regulatory proteins of proanthocyanidin biosynthesis were isolated. BnTT2-1, BnTT2-2, and BnTT2-3 are 1102 bp with two introns, and have a 938-bp full-length cDNA with a 260 amino acid open reading frame. They share 98....

journal_title：Molecular biology reports

authors： Wei YL,Li JN,Lu J,Tang ZL,Pu DC,Chai YR

更新日期：2007-06-01 00:00:00

abstract：:In this work, we identified a gene from Theobroma cacao L. genome and cDNA libraries, named TcGlu2, that encodes a β-1,3-1,4-glucanase. The TcGlu2 ORF was 720 bp in length and encoded a polypeptide of 239 amino acids with a molecular mass of 25.58 kDa. TcGlu2 contains a conserved domain characteristic of β-1,3-1,4-glu...

journal_title：Molecular biology reports

authors： Britto DS,Pirovani CP,Andrade BS,Dos Santos TP,Pungartnik C,Cascardo JC,Micheli F,Gesteira AS

更新日期：2013-09-01 00:00:00

abstract：:Vitiligo is an acquired pigmentary disorder characterized by loss of epidermal melanocytes. A strong association at a single nucleotide polymorphism (SNP) rs11966200 within MHC region had been identified in a recent genome-wide association study of generalized vitiligo in Chinese Han population. This study aims to inv...

journal_title：Molecular biology reports

authors： Tang J,Liu JL,Zhang C,Hu DY,He SM,Zuo XB,Wang PG,Sun LD,Zhang XJ,Yang S

更新日期：2013-06-01 00:00:00

abstract：:Hypertension is the most widespread disease in the world affecting humans and imparts a significant cardiovascular and renal risk to patients, and extensive research over the past few decades has enhanced our understanding of the underlying pathogenesis of hypertension. A growing number of studies have shown that miRN...

journal_title：Molecular biology reports

authors： Miao C,Chang J,Zhang G

更新日期：2018-12-01 00:00:00

abstract：:Immunity and inflammation are well established factors in the pathogenesis of pulmonary arterial hypertension (PAH). We aimed to investigate whether dexamethasone (Dex), a potent immunosuppressant, could prevent the development of monocrotaline (MCT)-induced PAH in rats as compared with pyrrolidine dithiocarbamate (PD...

journal_title：Molecular biology reports

authors： Wang W,Wang YL,Chen XY,Li YT,Hao W,Jin YP,Han B

更新日期：2011-06-01 00:00:00

abstract：:A novel 4-hydroxyphenylpyruvate dioxygenase gene (designated as Smhppd) was cloned from hairy roots of Salvia miltiorrhiza Bung. The full-length cDNA of Smhppd was 1,736 bp long with an ORF (open reading frame) that putatively encoded a polypeptide of 481 amino acids, with a predicted molecular mass of 52.54 kDa. The ...

journal_title：Molecular biology reports

authors： Xiao Y,Di P,Chen J,Liu Y,Chen W,Zhang L

更新日期：2009-09-01 00:00:00

abstract：:Iron may be implicated in the generation of oxidative stress by the catalyzing the Haber-Weiss or Fenton reaction. On the other hand, oxidative stress has been implicated in the pathogenesis of age-related macular degeneration (AMD) and heme oxygenase-1 (HO-1), encoded by the HMOX1 gene and heme oxygenase-2 (HO-2), en...

journal_title：Molecular biology reports

authors： Synowiec E,Szaflik J,Chmielewska M,Wozniak K,Sklodowska A,Waszczyk M,Dorecka M,Blasiak J,Szaflik JP

更新日期：2012-03-01 00:00:00

abstract：:Due to being stable in the circulatory system plasma miRNAs have been detected in various diseases including coronary artery disease (CAD) which is the major cause of mortality and morbidity worldwide. Atherosclerosis is the major cause of CAD. The first and most important event in the progression of atherosclerosis i...

journal_title：Molecular biology reports

authors： Gorur A,Celik A,Yildirim DD,Gundes A,Tamer L

更新日期：2019-02-01 00:00:00

abstract：:Purified cucumber mosaic virus (CMV) RNA was reacted with NaIO4 and then [3H]KBH4 to label ends containing exposed 2',3'-hydroxyls. The four major RNA species were then fractionated by polyacrylamide gel electrophoresis. Analysis of digests of these RNAs by ribonucleases T1 plus T2, alkaline phosphatease, snake venom ...

journal_title：Molecular biology reports

authors： Symons RH

更新日期：1975-12-01 00:00:00

abstract：:Diabetes affects a variety of tissues including the central nervous system; moreover, some evidence indicates that memory and learning processes are disrupted. Also, oxidative stress triggers alterations in different tissues including the brain. Recent studies indicate mitochondria dysfunction is a pivotal factor for ...

journal_title：Molecular biology reports

authors： Osorio-Paz I,Ramírez-Pérez G,Hernández-Ramírez JE,Uribe-Carvajal S,Salceda R

更新日期：2018-10-01 00:00:00

abstract：:With an aim at detecting the ultra-low concentration of avian influenza virus (AIV), a highly sensitive hybrid assay based on immunology and polymerase chain reaction was developed. The TopYield microtiter plates were coated with ten-fold serial dilutions of H5N1 subtype AIV ranging from 10 EID(50 )ml(-1)~10(-4) EID(5...

journal_title：Molecular biology reports

authors： Deng MJ,Xiao XZ,Zhang YM,Wu XH,Zhu LH,Xin XQ,Wu DL

更新日期：2011-03-01 00:00:00

abstract：:Echinococcus granulosus is a parasitic helminth which affects both man and animals. During infection with larval stage of the organism secretory and membrane-bound (S/M) proteins play a meaningful role for evasion of immune system. Antigen B (AgB) is one of them. Present investigation has defined sequence diversity of...

journal_title：Molecular biology reports

authors： Pan D,Bera AK,Bandyopadhyay S,Das S,Rana T,Das SK,Bandyopadhyay S,Manna B,Bhattacharya D

更新日期：2011-03-01 00:00:00

abstract：:The recombinant catalytic subunit of human protein kinase CK2 bas been mutagenised at the C-terminal region in an attempt to induce this tail to fold. We suppose in fact that this unstructured C-terminus just might be responsible for the high degradability of the human enzyme. On the basis of theoretical calculations ...

journal_title：Molecular biology reports

authors： Grasselli E,Noviello G,Rando C,Nicolini C,Vergani L

更新日期：2003-06-01 00:00:00

abstract：:1-Deoxynojirimycin (DNJ), the main alkaloid in mulberry leaves, was recognized to treat patients with type 2 diabetes mellitus (T2DM). However, the regulatory mechanism of DNJ on glucose homeostasis was still unclear. In the present study, a safe concentration of 0.1-10 μmol/L for DNJ was incubated with mature 3T3-L1 ...

journal_title：Molecular biology reports

authors： Li Q,Wang Y,Dai Y,Shen W,Liao S,Zou Y

更新日期：2019-12-01 00:00:00

abstract：:RNA polymerase III in an extract of HeLa cells transcribes RNA 5S in size from genomic bovine DNA template. This RNA represents a major fraction of the RNA synthesized. 5S RNA is not transcribed from bovine chromatin at equivalent concentrations and RNA the size of tRNA or tRNA precursor is not detected. At low UTP co...

journal_title：Molecular biology reports

authors： Furth JJ,Su CY

更新日期：1983-08-01 00:00:00

abstract：:The multidrug and toxic compound extrusion (MATE) protein family is a newly discovered family of secondary transporters that extrude metabolic waste and a variety of antibiotics out of the cell using an electrochemical gradient of H+ or Na+ across the membrane. The main function of MATE gene family is to participate i...

journal_title：Molecular biology reports

authors： Li Y,He H,He LF

更新日期：2019-02-01 00:00:00

abstract：:Staudtia kamerunensis (Myristicaceae) or 'Niové' is an evergreen tree widespread in Central African moist forests. The bark and seeds are used in traditional medicine, yet the tree is mainly harvested for its high quality, multi-purpose timber. To facilitate sustainable harvesting and conservation of the species, we a...

journal_title：Molecular biology reports

authors： Vanden Abeele S,Hardy OJ,Janssens SB

更新日期：2018-10-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:By measuring the permeability across the lipid bilayer in the presence and absence of membrane-bound protein or glycoprotein it should be possible to get an impression concerning their ability to penetrate into the membrane bilayer. Proteins such as phospholipase A2 and acetylcholinesterase markedly increase the perme...

journal_title：Molecular biology reports

authors： Neitchev VZ,Bideaud FA

更新日期：1982-04-16 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:Tumor angiogenesis, a major requirement for tumor growth and metastasis, is regulated by pro- and anti-angiogenic factors. The aim of this study was to quantify the expression of angiogenic (VEGF, HIF-1α, Angiopiotein-2) and anti-angiogenic (endostatin, angiostatin and Thrombospondin-1) factors and to discern their cl...

journal_title：Molecular biology reports

authors： Sharma BK,Srinivasan R,Kapil S,Singla B,Chawla YK,Chakraborti A,Saini N,Duseja A,Das A,Kalra N,Dhiman RK

更新日期：2013-10-01 00:00:00

abstract：:As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, sc...

journal_title：Molecular biology reports

authors： Chen B,Pan W,Zhang L,Liu J,Ouyang H,Nie Q,Zhang X

更新日期：2014-10-01 00:00:00

abstract：:Caspases have been demonstrated to possess important functions in apoptosis and immune system in vertebrate. But there is less information reported on the oyster larval development. In the present work, two full-length molluscan caspase genes, named Cacaspase-2 and Cacaspase-3, were characterized for the first time fr...

journal_title：Molecular biology reports

authors： Yang B,Li L,Pu F,You W,Huang H,Ke C

更新日期：2015-05-01 00:00:00

abstract：:The Giant Panda is an endangered and valuable gene pool in genetic, its important functional gene POLR2H encodes an essential shared peptide H of RNA polymerases. The genomic DNA and cDNA sequences were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) adopting touchdown-PCR and reve...

journal_title：Molecular biology reports

authors： Du YJ,Hou YL,Hou WR

更新日期：2013-02-01 00:00:00

abstract：:Transgenic doubled haploid rapeseed (Brassica napus L. cvs. Global and PF(704)) plants were obtained from microspore-derived embryo (MDE) hypocotyls using the microprojectile bombardment. The binary vector pCAMBIA3301 containing the gus and bar genes under control of CaMV 35S promoter was used for bombardment experime...

journal_title：Molecular biology reports

authors： Abdollahi MR,Moieni A,Mousavi A,Salmanian AH

更新日期：2011-02-01 00:00:00

abstract：:Protein profile of the skeletal muscle of Takifugu rubripes, a kind of pufferfish, was carried out with two-dimensional polyacrylamide gel electrophoresis (2-DE). Among the 112 protein spots detected in a silver-stained 2-D polyacrylamide gel, 33 were analyzed by Matrix Assisted Laser Desorption Ionisation tandem time...

journal_title：Molecular biology reports

authors： Lu J,Zheng J,Liu H,Li J,Chen H,Chen K

更新日期：2010-06-01 00:00:00

abstract：:Circulating long noncoding RNAs as biomarkers of diseases have attracted increasing attention recently. However, circulating lncRNAs in hypertension is still unexplored niche. The levels of lncRNAs GAS5, NR024118, MRAK134679, AX765700 and MRNR026574 were measured in the serum and myocardium of hypertensive rats and no...

journal_title：Molecular biology reports

authors： Wu Y,Zhang Z,Ren S,Li K,Ning Q,Jiang X

更新日期：2019-12-01 00:00:00

abstract：:The complete mitochondrial genome of Pseudochauhanea macrorchis was determined and compared with other monogenean mitochondrial genomes from GenBank. The circular genome was 15,031 bp in length and encoded 36 genes (12 protein-coding genes, two ribosomal RNAs, and 22 transfer RNAs) typically found in flatworms. Struct...

journal_title：Molecular biology reports

authors： Zhang J,Wu X,Xie M,Li A

更新日期：2012-08-01 00:00:00

abstract：:The novel dipstick DNA extraction method was tested for its reliability and usability for biological barcoding in comparison to a commercial kit and to a simplified isopropanol precipitation method using crayfish gill tissue. Following DNA extraction, the mitochondrial COI-gene was amplified in a PCR-reaction using a ...

journal_title：Molecular biology reports

authors： Martello A,Lambert B,Johnston C,Cutler J,Stumpf CF

更新日期：2019-12-01 00:00:00