Isolation of microsatellite loci in the African tree species Staudtia kamerunensis (Myristicaceae) using high-throughput sequencing.

abstract：:The aim of this study was to determine whether the Glutathione S-transferase M1 (GSTM1) and P1 (GSTP1) polymorphisms confer susceptibility to rheumatoid arthritis (RA). Meta-analysis was performed on the associations between the GSTM1 and GSTP1 null genotypes and RA, and on the association between smoking or seroposit...

journal_title：Molecular biology reports

authors： Song GG,Bae SC,Lee YH

更新日期：2012-12-01 00:00:00

abstract：:Molecular DNA markers are used for detection of polymorphisms in individuals. As they are independent of developmental stage of the plant and environmental influences, they can be useful tools in taxonomy. The alleles of simple sequence repeat (SSR) markers (or microsatellites) are traditionally used to identify taxon...

journal_title：Molecular biology reports

authors： Tuler AC,Carrijo TT,Nóia LR,Ferreira A,Peixoto AL,da Silva Ferreira MF

更新日期：2015-11-01 00:00:00

abstract：:The response of the respiratory subsystem of oxidative phosphorylation to the environmental pollutant, 2,2',5,5'-tetrachlorobiphenyl (2,2',5,5'-TCB) was investigated by modular kinetic approach. The effects of 20 microM 2,2',5,5'-TCB on the activity of the respiratory chain modules in rat liver mitochondria oxidizing ...

journal_title：Molecular biology reports

authors： Mildaziene V,Nauciene Z,Krab K

更新日期：2002-01-01 00:00:00

abstract：:Recent evidence supports a role of Toll-like receptor (TLR) signaling in the development of atherosclerotic lesions. It was confirmed that the presence of functional TLR4 promotes a proinflammatory phenotype and proliferation of vascular smooth muscle cells (VSMCs). Here we tested whether designed TLR4 small interferi...

journal_title：Molecular biology reports

authors： Li H,Xu H,Liu S

更新日期：2011-02-01 00:00:00

abstract：:Although it is known that the hybrid male mouse is sterile just like any other animal's heterogametic sex, the reason why only the male germ cells are impaired has yet to be discovered. TdT-mediated dUTP nick end labeling assay using a confocal fluorescence microscope and DNA fragmentation assay of hybrid testis indic...

journal_title：Molecular biology reports

authors： Hayashida K,Kohno S

更新日期：2009-07-01 00:00:00

abstract：:Diabetes affects a variety of tissues including the central nervous system; moreover, some evidence indicates that memory and learning processes are disrupted. Also, oxidative stress triggers alterations in different tissues including the brain. Recent studies indicate mitochondria dysfunction is a pivotal factor for ...

journal_title：Molecular biology reports

authors： Osorio-Paz I,Ramírez-Pérez G,Hernández-Ramírez JE,Uribe-Carvajal S,Salceda R

更新日期：2018-10-01 00:00:00

abstract：:Several lines of evidence suggest that the ubiquitin-proteasome pathway is involved in sepsis-induced muscle catabolism. The gene expression of ubiquitin and several of the proteasome subunits was increased in muscle from both septic rats and patients. In other studies, the activity of isolated 20S proteasomes was sti...

journal_title：Molecular biology reports

authors： Hasselgren PO

更新日期：1999-04-01 00:00:00

abstract：:Lac insects are commercial scale insects with high economic value. The combined molecular phylogeny of 20 lac insect populations was generated using elongation factor 1 alpha, mitochondrial cytochrome c oxidase subunit I and the small subunit ribosomal RNA gene loci. The 20 populations of lac insects clustered into fo...

journal_title：Molecular biology reports

authors： Chen H,Chen X,Feng Y,Yang H,He R,Zhang W,Yang Z

更新日期：2013-10-01 00:00:00

abstract：:Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) plays a pivotal role in regulating T cell activation, which is believably critical for the outcome of hepatitis B virus (HBV) infection. The expression and function of CTLA-4 may be affected by gene polymorphisms. This study investigated the influence of CTLA-4 poly...

journal_title：Molecular biology reports

authors： Duan S,Zhang G,Han Q,Li Z,Liu Z,Chen J,Lv Y,Li N,Wang Y,Li M,Lou S,Yang M,Zhu Q,Xing F

更新日期：2011-11-01 00:00:00

abstract：:Bone abnormalities as a consequence of osteoblast deregulation are associated with several diseases such as diabetes and chronic kidney disease. Important role for oxidized low density lipoproteins (oxLDL) in the pathophysiology of bone disorders has been reported. However, little is known about the effects and mechan...

journal_title：Molecular biology reports

authors： Dawodu D,Patecki M,Dumler I,Haller H,Kiyan Y

更新日期：2019-06-01 00:00:00

abstract：:Statins have shown pleiotropic effects, many of them independent of their impact on lipids. Angiogenesis can be beneficial in the acute myocardial infarction to improve circulation. However, it also can be harmful due to worsening of atherosclerosis. Here, we established a new minimal invasive rabbit model to study is...

journal_title：Molecular biology reports

authors： Shen W,Shi HM,Fan WH,Luo XP,Jin B,Li Y

更新日期：2011-08-01 00:00:00

abstract：:The aim of this work was to sequence the promoter region of β-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and align...

journal_title：Molecular biology reports

authors： Mastrangelo S,Sardina MT,Riggio V,Portolano B

更新日期：2012-01-01 00:00:00

abstract：:Hypertension is a risk factor for the cardiovascular diseases. Although, several drugs are used to treat hypertension, the success of the antihypertensive therapy is limited. Resveratrol decreases blood pressure in animal models of hypertension. This study researched the mechanisms behind the effects of resveratrol on...

journal_title：Molecular biology reports

authors： Han S,Uludag MO,Usanmaz SE,Ayaloglu-Butun F,Akcali KC,Demirel-Yilmaz E

更新日期：2015-01-01 00:00:00

abstract：:FK-506 binding proteins (FKBPs) belong to the peptidyl-prolyl cis/trans isomerase superfamily (PPIases, EC: 5.2.1.8) which catalyzes the interconversion of peptidyl-prolyl bonds while they can also act on polypeptides, as folding helper enzymes. Here, we biochemically characterize two recombinant FKBPs, AvfkbA1 and Av...

journal_title：Molecular biology reports

authors： Dimou M,Zografou C,Venieraki A,Katinakis P

更新日期：2012-12-01 00:00:00

abstract：:Familial hypercholesterolemia (FH) (OMIM 143890) is an autosomal dominantly inherited disease mainly caused by mutations of the gene encoding the low density lipoprotein receptor (LDLR) and Apolipoprotein (Apo) B. First the common mutation R3500Q in ApoB gene was determined using PCR/RFLP method. Then the LDLR gene wa...

journal_title：Molecular biology reports

authors： Cheng X,Ding J,Zheng F,Zhou X,Xiong C

更新日期：2009-11-01 00:00:00

abstract：:Two genes HPC/ELAC-2 and AAT were studied in north Indian population. HPC/ELAC-2 was studied in prostate cancer cases and AAT was studied in COPD patients. HPC/ELAC-2 is considered as an important cancer-susceptibility gene in prostate cancer. There are two common polymorphisms of this gene, i.e., Ser217Leu and Ala541...

journal_title：Molecular biology reports

authors： Sobti RC,Thakur H,Gupta L,Janmeja AK,Seth A,Singh SK

更新日期：2011-06-01 00:00:00

abstract：:DNA-, RNA- and protein synthesis have been studied in Mycobacterium smegmatis cells infected with phage I3. The macromolecular synthesis continued until the end of latent period. Early RNA and protein synthesis were necessary prior to the commencement of DNA replication. The infecting phage DNA sedimented as larger th...

journal_title：Molecular biology reports

authors： Nagaraja V,Gopinathan KP

更新日期：1981-11-30 00:00:00

abstract：:Groups of CBA mice were administered [35S] methionine (1 mCi/mouse). Non-histone proteins, H1 and H1(0) histones and nucleosomal core histones were isolated from different issues by selective extractions. The measurements of radioactivity of individual bands and autoradiography of dry gels were used to identify methio...

journal_title：Molecular biology reports

authors： Medvedev ZA,Medvedeva MN

更新日期：1988-01-01 00:00:00

abstract：:The difference in sensitivity of polyphenylalanine synthesis in extracts from Artemia salina and rabbit reticulocytes to inhibition by the Phytolacca americana protein (PAP) has been found to be linked to the source of the supernatant enzyme fraction and not the ribosomes. In the presence of reticulocyte supernatant e...

journal_title：Molecular biology reports

authors： Suits JP,Irvin JD

更新日期：1976-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) can be classified into six major genotypes. The HCV genotypes variability accounts for its geographical distribution, its responses to treatments and the clinical outcomes. The aim of this study was to determine the distribution of HCV genotypes among volunteer blood donors in Thailand. Samples...

journal_title：Molecular biology reports

authors： Sistayanarain A,Kunthalert D,Vipsoongnern Y

更新日期：2011-10-01 00:00:00

abstract：:Studies of the refractive properties of Gramicidin A in absolute ethanol and in ethanol water mixtures showed that this peptide in solution undergoes a conformational transition resulting in species with different refractivity. Accordingly, the folded form of this peptide shows a lower specific refractive index increm...

journal_title：Molecular biology reports

authors： Derechin M,Jordan BE

更新日期：1975-07-01 00:00:00

abstract：:ColE1 DNA replication is initiated by RNA II and inhibited by RNA I. Control of the replication occurs through the interaction between RNA I and RNA II. Therefore, RNases involved in the metabolism of RNA I and RNA II are expected to play a key role in the control of the ColE1 plasmid replication. RNase H, RNase E, RN...

journal_title：Molecular biology reports

authors： Jung YH,Lee Y

更新日期：1995-01-01 00:00:00

abstract：:Combined treatment with niacin and chromium has been found to have a protective effect against oxidative damage to different tissues of hyperlipidemic rats. But its effects on vascular endothelial dysfunction are less clear. This study was performed to investigate the effect of combined treatment with niacin and chrom...

journal_title：Molecular biology reports

authors： Niu N,Yu YH,Wang Y,Wang LJ,Li Q,Guo LM

更新日期：2009-07-01 00:00:00

abstract：:Heparan sulfate proteoglycans (HSPGs) located at the cell surface and in the extracellular matrix of most animal tissues are proteoglycan coreceptors that carry heparan sulfate chains, and play a vital role in infections of many diseases. HSPGs are classified as glypican, syndecan, perlecan and agrin according to diff...

journal_title：Molecular biology reports

authors： Wang W,Tao C,Zhou P,Zhou X,Zhang Q,Liu B

更新日期：2013-03-01 00:00:00

abstract：:Purified cucumber mosaic virus (CMV) RNA was reacted with NaIO4 and then [3H]KBH4 to label ends containing exposed 2',3'-hydroxyls. The four major RNA species were then fractionated by polyacrylamide gel electrophoresis. Analysis of digests of these RNAs by ribonucleases T1 plus T2, alkaline phosphatease, snake venom ...

journal_title：Molecular biology reports

authors： Symons RH

更新日期：1975-12-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) has been investigated extensively at the molecular level. Nevertheless, genome wide study on the temporal and spatial dynamics of the virus is non-existed. To explore this topic, we determined complete coding genome sequences for four PRRSV isolates and analy...

journal_title：Molecular biology reports

authors： Yoon SH,Kim H,Kim J,Lee HK,Park B,Kim H

更新日期：2013-10-12 00:00:00

abstract：:GASA-like genes form multigene families in diverse plant species and encode the proteins with a unique cysteine-rich domain (GASA domain). In our previously work, we cloned a GASA-like gene PRGL (Proline-rich GASA-like) from gerbera. Here we report the expression profiles of PRGL and the subcellular localization of PR...

journal_title：Molecular biology reports

authors： Peng J,Lai L,Wang X

更新日期：2010-10-01 00:00:00

abstract：:A cDNA encoding an O-methyltransferase (namely FGCOMT1) was identified from the medicinal plant Trigonella foenum-graecum L. The FGCOMT1 enzyme is a functional caffeic acid O-methyltransferase (COMT) and is localized in the cytosol. Kinetic analysis indicated that FGCOMT1 protein exhibited the highest catalyzing effic...

journal_title：Molecular biology reports

authors： Qin JC,Zhang YM,Lang CY,Yao YH,Pan HY,Li X

更新日期：2012-02-01 00:00:00

abstract：:Complexity is one of the hallmarks that applies to C2H2 type zinc finger proteins (ZFPs). Structurally distinct clusters of zinc finger modules define an extremely large superfamily of nucleic acid binding proteins with several hundred, perhaps thousands of different members in vertebrates. Recent discoveries have pro...

journal_title：Molecular biology reports

authors： Pieler T,Bellefroid E

更新日期：1994-07-01 00:00:00

abstract：:Transcription factor RBP-J-mediated Notch signaling has been implicated in several inherited cardiovascular diseases including aortic valve diseases (AVD). But whether Notch signal plays a role in AVD in adults has been unclear. This study aims to test whether the deletion of RBP-J in adult mice would lead to AVD and ...

journal_title：Molecular biology reports

authors： Li Z,Feng L,Wang CM,Zheng QJ,Zhao BJ,Yi W,Zhang JZ,Wang YM,Guo HT,Yi DH,Han H

更新日期：2012-04-01 00:00:00